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Health

The Delta Variant Is the Symptom of a Larger Menace: Vaccine Refusal

Of the 39 percent of unvaccinated adults, around half say they are not vaccinated at all. But even within this group, some say they would do it if asked to.

Understand the state of vaccine mandates in the United States

Some are hesitant and may come with the right conviction from people they trust, while still others plan to get vaccinated but say they just didn’t stand a chance.

Politics is only a driver for some of these people, noted Dr. Richard Besser, a former director of the Centers for Disease Control and Prevention. In New Jersey, where he lives, rates fluctuate dramatically due to socio-economic factors. In the predominantly white Princeton, 75 percent of adults are vaccinated, compared to 45 percent in Trenton, only 22 kilometers away, which is very black and Latin American.

“Both are strong democratic areas so it’s really important to break things down and address the issues that are hindering vaccination progress in every segment of the unvaccinated population,” said Dr. Better.

However, there is no doubt that the political divide is playing a role in the rising infection rates. From the start, vaccinations in counties that voted for Donald J. Trump have lagged behind those in counties that voted for Joseph R. Biden, and the gap has only widened – from two percentage points in April to now almost 12 points, according to a recent survey by the Kaiser Family Foundation.

According to another poll nationwide, 86 percent of Democrats got at least one shot, compared with 52 percent of Republicans. Even the national goal of getting 70 percent of adults vaccinated by July 4th somehow became “Biden’s goal,” said Dr. Nahid Bhadelia, director of the Center for Emerging Infectious Diseases Policy and Research at Boston University.

“Suddenly, even getting out of the pandemic became a left-versus-right problem.”

As of May, fewer than half of Republicans in the House of Representatives are vaccinated, compared with 100 percent of Democrats in Congress. For months, several Republican lawmakers, including Senators Ron Johnson from Wisconsin and Rand Paul from Kentucky, as well as conservative news commentators like Tucker Carlson, have voiced their skepticism about vaccines.

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Health

Israeli Knowledge Suggests Potential Waning in Effectiveness of Pfizer Vaccine

As Israel struggles with a new surge of coronavirus cases, its health ministry reported on Thursday that although effectiveness of the Pfizer-BioNTech vaccine remains high against severe illness, its protection against infection by the coronavirus may have diminished significantly compared with this winter and early spring.

Analyzing the government’s national health statistics, researchers estimated that the Pfizer shot was just 39 percent effective against preventing infection in the country in late June and early July, compared with 95 percent from January to early April. In both time periods, however, the shot was more than 90 percent effective in preventing severe disease.

Israeli scientists cautioned that the new study is much smaller than the first and that it measured cases in a narrower window of time. As a result, a much larger range of uncertainties flank their estimates, which could also be skewed by a variety of other factors.

Dr. Ran Balicer, the chairman of Israel’s Covid-19 National Expert Advisory Panel, said that the challenges of making accurate estimates of vaccine effectiveness were “immense.” He said that more careful analysis of the raw data was needed to understand what is going on.

“I think that data should be taken very cautiously because of small numbers,” said Eran Segal, a biologist at the Weizmann Institute of Science who is a consultant to the Israeli government on vaccines.

Nevertheless, the new estimates are raising concern both in Israel and elsewhere, including the United States, that the vaccine might be losing some of its effectiveness. Possible reasons include the rise of the highly contagious Delta variant or a waning of protection from the shots over time.

Israel launched an aggressive campaign with the Pfizer vaccine in January, and the country has achieved one of the highest vaccination rates in the world, with 58 percent of the population fully vaccinated. At the start of the campaign, government researchers began estimating how much the shot reduced people’s risk of getting Covid-19.

They published their results in May, based on records from Jan. 24 to April 3: They estimated that the vaccine was 95 percent effective in preventing infection from the coronavirus in the country. In other words, the risk of getting Covid-19 was nearly 100 percent reduced in vaccinated people compared to unvaccinated ones. The researchers also estimated that the vaccine was 97.5 percent effective against severe disease.

From a peak of over 8,600 cases a day in January, cases plummeted in the following months until only a few dozen people were testing positive on a daily basis across Israel. The vaccine most likely played a part in that drop, along with the tight restrictions that the government imposed on travel and meetings.

Israel began relaxing its restrictions in the spring. In late June, the cases surged again. Now, over a thousand people are testing positive each day, leading Israel to restore some restrictions this week.

Updated 

July 23, 2021, 2:47 p.m. ET

Some of the people that tested positive for the coronavirus in the new surge were fully vaccinated. Epidemiologists had expected such breakthrough infections, as they do with all vaccines.

Researchers at the Ministry of Health took another look at the effectiveness of the vaccine, limiting their analysis to the surge from June 6 to July 3. In that period, they estimated, the effectiveness of the vaccine at preventing infections was down to 64 percent.

More recently, they ran another analysis. This time, they looked at cases between June 20 and July 17. In that period, they estimated, the vaccine’s effectiveness was even lower: just 39 percent against infection.

Still, they estimated that the vaccine’s effectiveness against serious disease remained high, at 91.4 percent.

If a vaccine has an effectiveness of 39 percent that does not mean that 61 percent of people who got vaccinated were infected by the coronavirus. Instead, it means the risk of getting infected is 39 percent less among vaccinated people compared to unvaccinated. So even at that lower percentage, the data shows that vaccinated people have significantly less risk of getting infected than unvaccinated people.

The small number of people in the latest study means that the true effectiveness might be lower or higher. Making the numbers even more uncertain is the fact that the new surge has not yet spread evenly across the whole country. Travelers who have picked up the highly contagious Delta variant have brought it back to neighborhoods where vaccination rates are relatively high.

Understand the State of Vaccine Mandates in the U.S.

The new outbreaks have yet to swamp communities of Orthodox Jews or Arab Israelis, where vaccination rates are lower. That imbalance may make the vaccine seem less effective than it really is.

Also, the ages of people vaccinated vary significantly during the different time periods studied. For example, the people who got their vaccines in January were different than those who got them in April in one major respect: They were over 60. If more people who got vaccinated in January are now getting infected, it may not have to do with the vaccine itself, but with their advanced age — or some other factor that researchers have yet to take into consideration.

Still, the new estimates have prompted some researchers to ponder what might be happening to the vaccines. The Delta variant grew more common in Israel in June, raising the possibility that it might be good at evading the vaccine.

In Britain, where Delta began surging earlier in the year, researchers estimated the effectiveness of the Pfizer-BioNTech vaccine against the variant, based on a review of everyone in the United Kingdom who got vaccinated up till May 16. On Wednesday, they reported in the New England Journal of Medicine that it is 88 percent effective against symptomatic Covid-19.

Another possibility is that the Pfizer-BioNTech vaccine is gradually becoming less potent. The Ministry of Health researchers found that people who were inoculated in January were having breakthrough infections at a greater rate than people vaccinated in April.

If the vaccine is indeed waning after six months, the implications can be enormous. It can influence the Israeli government’s current deliberations about whether to give people a third shot. Dr. Segal says that if the vaccines are indeed losing some of their potency, then it might be wise to roll out boosters to fight the Delta-driven outbreak.

“If a third booster is safe and if it seems that it really would give a benefit, I think this is something we should definitely do as quickly as possible,” he said.

Dr. Balicer, who is also the chief innovation officer at Clalit Health Services, said that he and his colleagues are working on their own study on the effectiveness of the vaccine in Israel, using Clalit’s health care records to take into account such confounding factors.

“I think there is definitely some waning, but not as much as hypothesized based on the crude data, and it’s not just waning to blame,” Dr. Balicer said. “We are now trying to figure it out in a clean way.”

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Health

Pfizer Covid vaccine 39% efficient in Israel, prevents extreme sickness

People will be given a dose of the Pfizer BioNTech Covid-19 vaccine at a Covid-19 mass vaccination center on Rabin Square in Tel Aviv, Israel on Monday January 4, 2020.

Kobi Wolf | Bloomberg | Getty Images

Pfizer and BioNTech’s Covid-19 vaccine is only 39% effective in Israel, where the Delta variant is the dominant strain, but still offers strong protection against serious illness and hospitalization, according to a new report from the country’s health ministry.

The efficacy figure, based on an unspecified number of people between June 20 and July 17, is down from a previous estimate of 64% two weeks ago and is in conflict with data from the UK that showed the Vaccination was 88% effective against symptoms, disease caused by the variant.

However, the two-dose vaccine still works very well in preventing serious illness, showing 88% effectiveness against hospitalization and 91% effectiveness against serious illness, according to Israeli data released Thursday.

“We have to keep in mind that these vaccines can become less effective over time,” said Dr. Isaac Bogoch, professor of infectious diseases at the University of Toronto.

He stressed that the syringes are still highly effective in preventing serious infections and helping hospital systems not get overwhelmed in the colder months. “We are still in the Covid era and anything can happen,” he said.

“We have to be prepared and we have to be agile that at some point people will need a booster,” he added. “This close monitoring, which is happening in places like Israel, the UK and other parts of the world, will be very helpful in moving policy forward when and when we need boosters.”

The Delta variant, which is already present in more than 104 countries, worries US health officials as they detect more breakthrough infections in fully vaccinated people, even though they are milder.

The Chief Medical Officer of the White House, Dr. Anthony Fauci said people who are fully vaccinated should consider wearing masks indoors as a precaution against the rapidly spreading variant in the US

“Of course we don’t want to see that,” said Fauci on Wednesday, referring to the so-called breakthrough infections. “This virus is very different from the viruses and variants that we have previously experienced. It has an exceptional ability to transmit from person to person.”

Dr. Paul Offit, who advises the FDA on Covid vaccines, said that while the vaccines still offer great protection against serious illness and death, they may not work as well against mild cases or the transmission of the disease to others.

He urged more Americans to get vaccinated, saying Delta was a highly contagious virus and the vaccinations would help people get seriously ill. Currently, less than half of the US population is fully vaccinated, according to data compiled by the CDC.

“This is rich and fertile soil for the virus to continue to reproduce and keep creating variants that may become increasingly resistant to vaccines or natural infections,” he said.

The report from Israel, which began vaccinating its people before many other countries, is likely to back up the arguments made by drug manufacturers that people will eventually need to be given a booster to protect themselves from new variants.

Pfizer said earlier this month that immunity is waning from its two-dose vaccine and is now planning to seek approval from the Food and Drug Administration for a booster dose. However, federal officials say that fully vaccinated Americans do not currently require additional vaccinations.

In a statement to CNBC, Pfizer said it remains confident that its two-dose regimen will protect against the coronavirus and its variants.

Still, it said a third dose might help after analysis from its Phase III study showed a decrease in effectiveness against symptomatic infections after four to six months.

“Initial data from a third dose of the current vaccine shows that a booster dose given at least 6 months after the second dose induces high neutralization titers against wild-type and beta that are 5 to 10 times higher than after two primary doses. “Said the company.

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Health

Ought to Folks Who Took The Covid-19 Vaccine Begin Sporting Masks Once more?

Since the delta variant is spreading among the unvaccinated, many fully vaccinated people also worry. Is it time to mask again?

While there is no one-size-fits-all answer to the question, most experts agree that masks remain a wise precaution in certain situations for both vaccinated and unvaccinated people. How often you use a mask depends on your personal health tolerance and risk, the infection and vaccination rates in your community, and who you spend time with.

The bottom line is this: while a full vaccination protects against serious illness and hospitalization from Covid-19, no vaccine offers 100 percent protection. As long as large numbers of people remain unvaccinated and the coronavirus continues to spread, those vaccinated will be exposed to the Delta variant and a small percentage of them will develop what are known as breakthrough infections. Here you will find answers to frequently asked questions about how to protect yourself and reduce your risk of a breakthrough infection.

To decide if a mask is needed, first ask yourself these questions.

  • Are the people I am with also vaccinated?

  • What is the fall and vaccination rate in my community?

  • Will I be in a poorly ventilated indoor or outdoor area? Will the increased risk of exposure last a few minutes or hours?

  • How high is my personal risk (or the risk to my fellow human beings) for complications from Covid-19?

Experts agree that you don’t need to wear a mask if everyone you are with is vaccinated and symptom-free.

“I don’t wear a mask when hanging out with other people who have been vaccinated,” said Dr. Ashish K. Jha, Dean of Brown University School of Public Health. “I don’t even think about it. I go to the office with a few people and they are all vaccinated. I’m not worried. “

But once you venture into closed public spaces, where the chances of encountering unvaccinated people are greater, a mask is probably a good idea. A full vaccination remains the strongest protection against Covid-19, but the risk is cumulative. The more opportunities you give the virus to challenge the antibodies you made with your vaccine, the higher your risk of exposure to exposure so great that the virus breaks the protective barrier of your immune system.

Because of this, your community’s fall and vaccination rate is one of the most important factors influencing mask needs. For example, in Vermont, Massachusetts, Connecticut, and Rhode Island, more than 70 percent of adults are fully vaccinated. In Alabama, Mississippi, and Arkansas, fewer than 45 percent of adults are vaccinated. In some counties, overall vaccination rates are far lower.

“We are currently two Covid nations,” said Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine and co-director of the Center for Vaccine Development at Texas Children’s Hospital. In Harris County, Texas, where Dr. Hotez is alive, case numbers are up 114 percent in the past two weeks, and only 44 percent of the community is fully vaccinated. “I wear a mask indoors most of the time,” said Dr. Hotez.

Finally, masking is more important in poorly ventilated indoor spaces than outdoors, where the risk of infection is extremely low. Dr. Jah notices that he recently stormed into a cafe, exposed because vaccination rates are high in his area, and was only there for a few minutes.

Your personal risk also counts. If you are elderly or have immunocompromised your antibody response to the vaccine may not be as strong as a young person’s response. It is a good idea to avoid crowded rooms and wear a mask if you are indoors and do not know the vaccination status of those around you.

Use the Times tracker to find vaccination rates and case numbers in your area.

When the US Centers for Disease Control and Prevention announced that people who had been vaccinated could forego wearing masks, the number of cases declined, vaccinations increased, and the highly contagious Delta variant had not yet caught on. Since then, Delta has spread rapidly and now accounts for more than 83 percent of cases in the United States.

It is known that people infected with the Delta variant shed much higher amounts of the virus over longer periods of time compared to previous lines of the coronavirus. A preliminary study estimated that viral loads are 1,000 times higher in people with the delta variant. These high viral loads give the virus more opportunities to challenge your antibodies and breach your vaccine protection.

“This is twice as transferable as the original line from Covid,” said Dr. Hotez. “The reproductive number of the virus is around 6,” he said, referring to the number of people a virus carrier is likely to infect. “That means that 85 percent of the population must be vaccinated. Only a few areas of the country achieve that. “

Updated

July 22, 2021, 1:43 p.m. ET

The answer depends on your personal risk tolerance and the level of vaccinations and Covid-19 cases in your community. The more time you spend with unvaccinated people in closed rooms for a long time, the higher the risk of crossbreeding with the Delta variant or other variants that may appear.

Large gatherings, by definition, offer more opportunities to contract the coronavirus, even if you are vaccinated. Scientists have documented breakthrough infections at a recent Oklahoma wedding and July 4th celebrations in Provincetown, Massachusetts.

But even with the Delta variant, a full vaccination seems to be around 90 percent effective to prevent serious illnesses and hospital stays caused by Covid-19. However, if you are at a very high risk of complications from Covid-19, you should consider avoiding risky situations and wearing a mask if the vaccination status is unknown to those around you.

Healthy vaccinated people with a low risk of complications have to decide what personal risk they want to accept. Wearing a mask at large indoor gatherings will reduce the risk of infection. If you are healthy and vaccinated but are caring for an aging parent or spending time with others at high risk, you should also consider their risk when deciding whether to attend an event or wear a mask.

“When I go into a public area, I usually wear a mask,” said Dr. Hotez. “Until recently, I used to take my son and his girlfriend out to a restaurant for dinner and I wouldn’t wear a mask because the broadcast was so advanced. Now I’m not so sure. I can change the way I think about restaurants while Delta is getting faster. “

Breakthrough infections get a lot of attention because people who have been vaccinated talk about them on social media. If breakthrough infection clusters occur, it is also reported in science journals or in the media.

However, it’s important to remember that while breakthrough cases are relatively rare, they can still happen no matter what vaccine you’re given.

“No vaccine is 100 percent effective at preventing disease in vaccinated people,” says its CDC website. “There will be a small percentage of fully vaccinated people who will still get sick, hospitalized, or die of Covid-19.”

A breakthrough case doesn’t mean your vaccine isn’t working. In fact, most breakthrough infection cases result in no symptoms or only mild illness, which shows that the vaccines are working well to prevent serious illness from Covid-19.

As of July 12, more than 159 million people in the United States were fully vaccinated against Covid-19. Of these, only 5,492 had breakthrough cases that resulted in serious illness. including 1,063 who died. That’s less than 0.0007 percent of the vaccinated population. Now 99 percent of Covid-19 deaths are among the unvaccinated.

Many infectious disease experts are frustrated that the CDC only documents cases where a vaccinated person with Covid-19 is hospitalized or dies. But many breakthrough infections are still being discovered in asymptomatic people who are frequently tested, such as baseball players and Olympic athletes. Many of these people travel or spend long periods of time in close quarters with others.

“Sports figures are different,” said Dr. Yeh. “Part of the problem is that they also encounter a lot of unvaccinated people, even in their own small circle.”

If you’re fully vaccinated and know you’ve been exposed to someone with Covid-19, it’s a good idea to get tested even if you don’t have symptoms.

And if you have cold symptoms or other signs of infection, experts agree that you should be tested. Many vaccinated people who do not wear masks have caught colds in the summer, which lead to runny nose, fever and cough. But it’s impossible to tell the difference between a summer cold and Covid-19. Anyone with cough or cold symptoms should wear a mask to protect their surroundings and get tested to rule out Covid-19. It’s a good idea to have a few Covid tests on hand at home as well.

“If I woke up one morning and had symptoms of a cold, I would put on a mask at home and get tested,” said Dr. Yeh. “I don’t want to cause breakthrough infections in other members of my family, and I don’t want to give it to my 9 year old child.”

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Politics

Home Republicans Use Vaccine Press Convention to Bash Democrats

House Republican leaders and doctors rallied for a news conference Thursday morning allegedly to urge Americans to get the coronavirus vaccine amid rising infections in the United States, but they used the event to attack Democrats, from whom they are said they had misrepresented the origins of the virus with no evidence.

The appearance of second- and third-tier Republicans in the House of Representatives, Reps Steve Scalise from Louisiana and Elise Stefanik from New York, along with a dozen doctors suggested that a resurgence in the spread of the virus fueled by the more contagious Delta variant was not had taken place called on the party to change its tone. Instead, Mr. Scalise and Ms. Stefanik beat up the Democrats for what they called a cover-up on behalf of the Chinese Communist Party.

Only at the urging of reporters did the leaders mention vaccinations.

“I would encourage people to get the vaccine,” said Mr. Scalise towards the end of the event, when his position pushed him to do so. “I have great confidence in that. I got it myself. “

He and other Republicans spent most of Thursday discussing unsubstantiated claims that the Chinese released a virulent, man-made virus in the world, accusing Democrats of ignoring it.

The event in front of the Capitol was planned as a “press conference to discuss the need for vaccinations for individuals, uncover the origins of the pandemic and keep schools and businesses open”. Yet the Republicans who attended, many of whom represent constituencies that have refused to get the vaccine, seem unable to bring themselves to stress the importance of the move.

Even the doctors who emphasized vaccinations, Rep. Andy Harris from Maryland and Senator Roger Marshall from Kansas, quieter and narrowed their statements.

“If you are at risk you should get this vaccine,” said Dr. Harris, adding, “We urge all Americans to speak to their doctors about the risks of Covid, speak to their doctors about the benefits of vaccination, and” then make a decision that is right for them. “

The Centers for Disease Control and Prevention recommend that everyone aged 12 and over – not just those at higher risk – get the coronavirus vaccine as soon as possible.

North Carolina Republican Rep. Greg Murphy countered, “This vaccine is a medicine and, like any other medicine, there are side effects and this is a personal choice.”

The emphasis on the so-called lab leak theory was surprising given the surge in infections that were concentrated in rural, heavily Republican regions of the country.

Nationally, the average of new coronavirus infections in 14 days is up 171 percent to more than 41,300 a day on Wednesday, and the death toll – a delayed figure – is up 42 percent from two weeks ago to nearly 250, so a New York time database. Still, new cases, hospital admissions and deaths remain at a fraction of their previous devastating highs.

Vaccines remain effective against the worst effects of Covid-19, including the Delta variant. Experts say that breakthrough infections are still relatively rare in vaccinated people. The delta variant accounts for an estimated 83 percent of new cases in the United States, the CDC said earlier this week.

The Kaiser Family Foundation reported in late June that 86 percent of Democrats had at least one shot, compared to 52 percent of Republicans. An April analysis by the Times found that the country’s least vaccinated counties had one thing in common: they voted for Mr Trump.

But dr. Murphy said the notion that conservatives are reluctant to get the vaccine “isn’t just insincere; It is a lie.”

As for the theory of the laboratory leak, the Republicans successively presented the issue as practically done: Research in a virus laboratory in Wuhan, China, created the novel coronavirus through risky experiments to “gain functionality” and then released it into the world.

“Criminals have been convicted on less evidence than is currently the case, and more evidence is being revealed every day,” said Iowa representative Mariannette Miller-Meeks.

Recently, some scientists have urged the possibility of a laboratory leak to be taken seriously, along with the possibility that the coronavirus emerged naturally, most likely from an animal. But they are mainly testing the possibility that a naturally developed virus was present in the laboratory and escaped, not that the virus was created on purpose. Even some of the most vocal scientific proponents of a laboratory leak do not claim that there is definitive evidence as to the origin of the virus.

Instead of covering up the matter, President Biden ordered U.S. intelligence services in late May to investigate the origins of the coronavirus and report back in 90 days.

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Politics

Biden predicts the F.D.A. will give ultimate approval to a Covid vaccine by the autumn.

President Biden told a town hall audience in Ohio on Wednesday evening that he expected the Food and Drug Administration would give final approval “quickly” for Covid-19 vaccines, as he pressed for skeptical Americans to get vaccinated and stop another surge of the pandemic.

Mr. Biden said he was not intervening in the decision of government scientists, but pointed toward a potential decision soon from the F.D.A. to give final approval for the vaccines, which are currently authorized for emergency use. Many medical professionals have pushed for the final approval, saying it could help increase uptake of the vaccines.

“My expectation talking to the group of scientists we put together, over 20 of them plus others in the field, is that sometime maybe in the beginning of the school year, at the end of August, beginning of September, October, they’ll get a final approval” for the vaccines at the F.D.A., Mr. Biden said.

The president also said he expected children under the age of 12, who are not currently eligible to receive the vaccine, would be approved to get it on an emergency basis “soon, I believe.”

The president’s comments at the town hall came as the spread of the Delta variant has led to a national rise in coronavirus cases. Over the past week, an average of roughly 41,300 cases has been reported each day across the country, an increase of 171 percent from two weeks ago. The number of new deaths reported is up by 42 percent, to an average of 249 a day for the past week.

In some states, such as Missouri, Arkansas, Louisiana and Florida, new infections have increased sharply, also driving an increase in hospitalizations. Cases are increasing more rapidly in states where vaccination rates are low.

In Ohio, where Mr. Biden traveled on Wednesday to talk up what he pitched as the good-paying union jobs that his infrastructure plan would create, the president found himself fielding questions from audience members concerned about low vaccination rates in their communities.

“This is simple, basic proposition,” he said. “If you’re vaccinated, you’re not going to be hospitalized. You’re not going to be in an I.C.U. unit. And you are not going to die.”

Later, Mr. Biden exaggerated the efficacy of the vaccine, even as some vaccinated staffers in the West Wing have recently tested positive for the coronavirus. “You’re not going to get Covid if you have these vaccinations,” he said.

In response to a move by Speaker Nancy Pelosi earlier Wednesday to bar two of former President Donald J. Trump’s most vociferous Republican defenders in Congress from joining a select committee to investigate the Jan. 6 riot at the Capitol, Mr. Biden was unequivocal about what happened that day.

“I don’t care if you think I’m Satan reincarnated, the fact is you can’t look at that television and say nothing happened on the sixth,” he said. “You can’t listen to people who say this was a peaceful march.”

But speaking in a red state that Mr. Trump won in the 2020 election, as he tries to build support for his infrastructure plans, Mr. Biden kept his criticism to some of the lawmakers elected to office, rather than Republican voters who got them there.

“I have faith in the American people, I do, to ultimately get to the right place,” he said. “Many times Republicans are in the right place.”

Jesus Jiménez contributed reporting.

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Health

Extra Hospitals Impose Vaccine Mandates for Staff

More and more hospitals and large health systems are requiring their employees to receive the Covid-19 vaccine, due to rising case numbers due to the Delta variant and persistently low vaccination rates in their communities and even within their workforce.

Many hospitals say their efforts to vaccinate their staff have stalled, just as the country’s overall vaccination rates remain below 60 percent, behind many European countries and Canada. While more than 96 percent of doctors say they are fully vaccinated, health workers, especially in rural areas, have been shown to be more resistant, according to the American Medical Association, although thousands of workers have died from the virus and countless more contracted.

A recent estimate suggests that one in four hospital workers had not been vaccinated by the end of May, with some facilities reporting that fewer than half of their staff had received the vaccination.

Some hospitals, from academic medical centers like New York-Presbyterian and Yale New Haven to big chains like Trinity Health, carry out a mandate because they realize that the only way to stop the virus is to have as many people as possible possible to vaccinate as soon as possible. A major Arizona-based chain, Banner Health, announced Tuesday that it would be issuing a mandate, and New York City said that all health care workers in city hospitals or clinics should be vaccinated or tested weekly.

The surge in cases led Trinity Health, a Catholic system with hospitals in 22 states, to become one of the first large groups to decide earlier this month to require vaccinations. “We believed the vaccine could save lives,” said Dr. Daniel Roth, Trinity’s Chief Clinical Officer. “These are preventable deaths.”

At UF Health Jacksonville, Florida, the number of Covid patients treated has increased to levels not seen since January, and only half of health care workers are vaccinated, said Chad Neilsen, director of infection prevention. 75 employees have contracted the virus, the vast majority of them unvaccinated, while others are waiting for test results. “We are currently having major problems with the staff,” he said.

“It’s like déjà vu,” said Neilsen, describing the growing frustration at colleagues’ refusal to get the recordings. “We have reason to believe that this could be over when people are vaccinated.”

Despite dozens of virtual town halls, question-and-answer sessions, and instructional videos, many employees are suspicious. “We are still stagnant,” said Mr Neilsen.

Some employees want more data, others think the process is too rushed. Much of the same conspiracy theories and misinformation – that the vaccines make women sterile or contain microchips – prevail among the staff. “Our healthcare workers are a reflection of the general population,” he said.

Hospital directors and others plan to meet with state officials in the coming weeks about the option to mandate, he said.

Unvaccinated workers continue to care for even the sickest patients, raising concerns that they are spreading the infection, especially now that the highly contagious Delta variant accounts for more than 80 percent of cases in the country.

“Nowhere is this more important than in hospitals where health workers – who were heroic during this pandemic – care for patients with a variety of health problems on the assumption that the healthcare professionals treating them are not at risk or transmission of Covid-19,” said Dr. David J. Skorton, chairman of the board of the Association of American Medical Colleges, which represents teaching hospitals, in a statement last Friday calling for a mandate.

On Wednesday, two more groups, including the American Hospital Association, joined the growing call for vaccine mandates. “We lost too many of our caregivers to Covid-19,” said Dr. Bruce Siegel, the executive director of America’s Essential Hospitals, which represents hospitals in underserved communities. “Vaccination can reduce the risk of losing more.”

With the formal approval of the vaccines by the Food and Drug Administration may still be months away, hospitals are at the center of the national mandate debate. While the vaccines are offered under an emergency license, proponents argue that there is ample evidence that the vaccines available in the United States are both safe and effective.

There is a new urgency in states like Missouri, which have reported a surge in cases. “We felt we couldn’t wait,” said Dr. Shephali Wulff, the director of infectious diseases at SSM Health, a Catholic hospital system headquartered in St. Louis. SSM, which now has about two-thirds of its employees vaccinated, requires everyone to get their first dose by September 1st.

SSM’s decision was also motivated by concerns that Covid infections could rise this fall when other respiratory infections could also rise. “We need healthy workers for the flu season,” said Dr. Wulff. “We don’t have time to wait for approval.”

However, some systems already fear staff shortages due to departures during the pandemic, as many employees quit because of stress and burnout in the care of Covid patients. Hospitals are reluctant to lose more staff when forcing the problem.

Updated

July 22, 2021, 1:43 p.m. ET

“They fear this could be a turning point,” said Ann Marie Pettis, president of the Association for Professionals in Infection Control and Epidemiology, one of the professional organizations calling on hospitals to request the vaccine.

At Mosaic Life Care, a small hospital group in Missouri, executives are reluctant to take on mandates when other hospitals fail. “We have the potential to lose some caregivers to other systems,” said Joey Austin, a spokeswoman for Mosaic, which has vaccinated about 62 percent of its employees.

Many hospitals already require their staff to have a flu shot, which has been around for over a decade. Although this met with resistance from employees who were skeptical about the safety of the vaccines, it is now widely accepted. Individuals can apply for a medical or religious exemption, which is typically a small portion of the workforce that hospitals say would also apply to the Covid vaccines.

Mandates “impose a social norm and say it is an institutional priority,” said Saad B. Omer, director of the Yale Institute for Global Health, who stressed that hospitals must strongly encourage their workers to receive the vaccines voluntarily, in order to be successful.

Unions like National Nurses United and 1199 SEIU say they want their members to be vaccinated but refuse to make it a condition of employment. At the first mandated hospital, the Houston Methodist, a group of staff sued to challenge the request, but the lawsuit was recently dismissed. Of a total workforce of around 26,000 people, around 150 left or were made redundant because they could not meet the vaccination deadline.

Hospitals say they are working hard to dispel much of the widespread misinformation surrounding the vaccines, even among doctors and nurses.

“I have to remind them that serious scientists do not post their results on YouTube,” said Dr. Wulff. She and her colleagues at SSM not only present hard data on the vaccine, but also share their personal experiences, such as being vaccinated while trying to get pregnant. “I find that stories and anecdotes move people,” she said.

“In general, you listen a lot and focus on what drives your fear,” said Dr. Wulff.

Some high profile systems like Intermountain Healthcare and the Cleveland Clinic are waiting. The clinic, which has an extensive network of 18 hospitals across the United States, said existing policies like masking and tracking infections protect patients and workers.

“We know that we can continue to protect our patients and caregivers by ensuring these safety precautions are in place,” said K. Kelly Hancock, chief caregiver officer, Cleveland Clinic.

About three-quarters of the staff are now vaccinated and efforts are continuing “at full speed,” she said.

At Intermountain Healthcare, based in Utah, “a good majority” of employees have been vaccinated, said Dr. Kristin Dascomb, medical director for infection prevention and control and employee health.

If more safety data is required and the FDA approves the vaccines, Intermountain, along with other hospitals in the state, can request a vaccination. “We’re starting the conversation in Utah now,” she said.

The lack of full FDA approval has affected other hospitals as well. Mass General Brigham, who vaccinated more than 85 percent of his workforce, said he would adopt the requirement once the vaccines are approved.

Some hospitals argue that a mandate is not required. “I don’t think there is one right answer,” said Suresh Gunasekaran, general manager of the University of Iowa Hospitals & Clinics. About 90 percent of workers are now vaccinated, he said, adding he was confident that virtually everyone will be vaccinated by the end of the year.

The system was “successful in eliminating vaccine hesitation,” Gunasekaran said, in part because Iowa was involved in clinical trials for the Pfizer BioNTech vaccine.

Northwell Health, the large New York hospital group, doesn’t require workers to be vaccinated against the flu, but about 90 percent of their workforce is vaccinated, said Maxine Carrington, Northwell’s chief human resources officer. The same applies to Covid.

“We want people to be believers,” said Ms. Carrington, so that they can better convince the entire ward to get vaccinated. She described the system as “beating the pavement on education, education, education”. Around 76 percent of the workforce are currently vaccinated against Covid. Northwell will reconsider the idea of ​​a mandate after the FDA approves the vaccines, she said.

Yale New Haven Health is now requiring employees to be vaccinated, as are the other Connecticut hospitals.

“From the beginning we pointed out that this is not mandatory – not yet. We emphasized that, ”said Dr. Thomas Balcezak, Yale’s chief clinical officer.

“The health system has to lead,” he said.

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Health

One Dose of J.&J. Vaccine Is Ineffective Towards Delta, Examine Suggests

The coronavirus vaccine manufactured by Johnson & Johnson is much less effective against the Delta and Lambda variants than against the original virus, according to a new study published online on Tuesday.

The results show that the 13 million people who used the J. & J. The vaccine may need to be given a second dose – ideally one of the Pfizer-BioNTech or Moderna mRNA vaccines, the authors said.

However, the conclusions contradict those from smaller studies published earlier this month by Johnson & Johnson, which suggest that a single dose of the vaccine is effective against the variant even eight months after being vaccinated.

The new study had not yet been peer-reviewed or published in a scientific journal and was based on laboratory experiments. However, it is consistent with observations that a single dose of the AstraZeneca vaccine – which has a similar architecture to the J. & J. Vaccine – only shows about 33 percent effectiveness against symptomatic diseases caused by the Delta variant.

“The message we wanted to get across wasn’t that people were making the J. & J. Vaccine, but we hope it will be reinforced with in the future either another dose of J. & J. or a boost with Pfizer or Moderna, ”said Nathaniel Landau, a virologist at NYU’s Grossman School of Medicine who led the study.

Other experts said the results are what they expected as all vaccines seem to work better when given in two doses. “I have always thought and often said that J. & J. Vaccine is a two-dose vaccine, ”said John Moore, a virologist at Weill Cornell Medicine in New York.

Dr. Moore pointed to several studies in monkeys and humans that showed greater effectiveness with two doses of the J. & J. Vaccine compared to a dose. He said the new study was particularly credible because it was published by a team with no ties to any of the vaccine manufacturers.

But the data from the new study “doesn’t speak about the whole nature of immune protection,” said Seema Kumar, a spokeswoman for J. & J. Company-sponsored studies suggest that the vaccine “produces strong, sustained activity against the rapidly spreading Delta variant,” she said.

The delta variant is the most contagious version of the coronavirus to date. It accounts for 83 percent of infections in the United States, said Dr. Rochelle Walensky, director of the Centers for Disease Control and Prevention, at a Senate hearing on Tuesday.

The variant could also be responsible for a recent surge in infections: although they’re still low compared to last winter, cases are increasing in all 50 states and hospital admissions are increasing in almost all. In the two weeks ended Tuesday, there were an average of 268 deaths per day in the nation.

Delta can cause more breakthrough infections than previous forms of the virus, but more than 99 percent of hospitalizations and deaths occur in unvaccinated people. The vaccination rates in the country have stalled, almost 60 percent of adults are fully protected against the virus.

Several studies have shown that Pfizer-BioNTech and Moderna’s mRNA vaccines retain their effectiveness against the coronavirus, including all variants identified so far. For example, a recent study showed that the vaccines trigger a sustained immune response in the body that can protect against the coronavirus for years.

Updated

July 20, 2021, 4:10 p.m. ET

But evidence for the J. & J. The vaccine was limited as it was introduced later than the mRNA vaccines. Most of the studies on the effectiveness of the coronavirus vaccines were conducted in medical centers and hospitals, based on samples from staff who had received the mRNA vaccines.

The J. & J. The vaccine has also been followed by reports of blood clots and a rare neurological syndrome, as well as contamination problems at a Baltimore manufacturing facility.

Small studies published by researchers associated with J. & J. suggested that the vaccine against the Delta variant was only slightly less effective than against the original virus and that the antibodies stimulated by the vaccine grew in strength within eight months.

Dr. Landau would likely have seen a similar increase in the vaccine’s effectiveness if they looked at the data over time, said Dr. Dan Barouch, a virologist at Beth Israel Deaconess Medical Center in Boston. The data for the J. & J. The strength of the vaccine against the Delta variant on day 29 is not much different from what was reported in his own study, said Dr. Barouch.

“Basically, I don’t see any discrepancies,” he said. “The question is that of kinetics, it’s not just size, because immune responses are not static over time.” The new study does not consider other components of the immune system either, he added.

Dr. Landau and colleagues examined blood samples from 17 people who received two doses of an mRNA vaccine and 10 people who received one dose of the J. & J. Vaccination.

The J. & J. Vaccine started with less potency than the mRNA vaccines and showed a greater potency drop against the Delta and Lambda variants. “The lower baseline means that what is left against Delta is very weak,” said Dr. Moors. “That is a major concern.”

Very few vaccines are given as a single dose because the second dose is needed to raise antibody levels, noted Akiko Iwasaki, an immunologist at Yale University. Persons familiar with the J. & J. Vaccines “rely on this primary response to maintain high levels of antibody, which is particularly difficult against the variants,” she said.

Boosting immunity with a second dose should raise antibody levels high enough to counter the variants, she said.

For the second shot, let’s turn to an mRNA vaccine rather than another J. & J. Shot, Possibly Better: Several studies have shown that combining a dose of the AstraZeneca vaccine with a dose of the Pfizer BioNTech or Moderna vaccine is more effective than two doses of AstraZeneca.

The Food and Drug Administration has said, “Americans who have been fully vaccinated don’t need a booster right now,” and the agency is unlikely to change its recommendations based on laboratory studies. But the new data should cause the FDA to reconsider its recommendations, said Dr. Landau: “I hope you read our paper and think about it.”

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Health

Infectious illness knowledgeable says Covid vaccine misinformation is ‘killing individuals’

Dr. Nahid Bhadelia, founding director of the Center for Emerging Infectious Diseases at Boston University, expressed concern about the spread of misinformation about Covid vaccines on social media.

“I think social media plays a huge role in amplifying misinformation that is leading people not to take the vaccine, which is killing them,” Bhadelia told CNBC on Friday. “It’s the honest truth. Covid is a vaccine-preventable disease at the moment.”

President Joe Biden said Friday that platforms like Facebook are killing people by allowing misinformation about Covid-19 vaccines through their services. He went back those comments on Monday, mainly accusing the platform’s users of sharing misinformation.

Bhadelia cited results from the Kaiser Family Fund poll, which found that 54% of Americans either believe or cannot tell whether a common Covid vaccine myth is fact or fiction.

The US is struggling with a drop in vaccination rates and an increase in infections. All 50 states have reported an increase in Covid cases over the past week, according to Johns Hopkins University. The US has an average of more than 26,000 new cases a day, and that’s the highest number in two months, according to Johns Hopkins.

Bhadelia told CNBC The News with Shepard Smith that she believes social media companies can do a lot more to stop the spread of disinformation.

“You have to invest a lot more resources and improve your balance to clear that information faster, invest more resources in changing your matrix, because right now what is on top of your page is not right, but what it is is popular, “said Bhadelia, a medical worker for NBC News.

She also suggested that social media companies should partner with public health officials more to get the right information out to the people.

Facebook spoke out against the White House claims.

“We will not be distracted by allegations that are not supported by the facts,” said a spokesman. “The fact is, more than 2 billion people have viewed authoritative information about COVID-19 and vaccines on Facebook, more than any other place on the internet. More than 3.3 million Americans have also used our vaccine finder tool to find out where and how to get a vaccine. The facts show that Facebook helps save lives. Point.”

Correction: This article has been updated to include Dr. Nahid Bhadelia’s view that “social media plays a huge role in amplifying misinformation” about Covid vaccines. An earlier version misinterpreted your quote.

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Politics

‘They’re killing individuals’ with vaccine misinformation

President Joe Biden said Friday that platforms like Facebook are killing people by allowing misinformation about Covid-19 vaccines through their services.

When asked what his message was regarding Covid disinformation on platforms like Facebook, Biden said: “They kill people”.

“I mean, they really, you see, the only pandemic we have is among the unvaccinated, and that is – they kill people,” said Biden on the South Lawn of the White House.

Biden echoed previous comments made by White House Press Secretary Jen Psaki.

“We are dealing with life or death here, so everyone has a role to play in making sure there is accurate information,” said Psaki. “They are a private sector company. They will make decisions about additional steps they can take. It is clear that more can be done.”

Psaki’s comments come a day after she said the Biden government reported problematic posts for Facebook that spread misinformation.

“We regularly make sure social media platforms are aware of the latest dangerous public health narratives that we and many other Americans see on all social and traditional media,” she said. “We are working to work with them to better understand the enforcement of the guidelines for social media platforms.”

An example highlighted by Psaki is the spread of a false narrative that coronavirus vaccines cause infertility.

“This is disturbing, but an ongoing narrative that we and many have seen, and we want to know that social media platforms are taking steps to address it,” said Psaki. “This is inaccurate, incorrect information.”

Psaki noted that Facebook and other social media services can take additional steps to combat misinformation. This includes publicly sharing the impact of misinformation on their services, promoting quality information, and taking faster action against harmful posts.

“As you all know, information travels pretty quickly,” she said. “If it’s up there for days, when people see it, it’s hard to put that back in a box.”

Facebook spoke out against the White House claims.

“We will not be distracted by allegations that are not supported by the facts,” said a spokesman. “The fact is, more than 2 billion people have viewed authoritative information about COVID-19 and vaccines on Facebook, more than any other place on the internet. More than 3.3 million Americans have also used our vaccine finder tool to find out where and how to get a vaccine. The facts show that Facebook helps save lives. Point.”