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Health

Pfizer begins early stage scientific trial testing oral antiviral drug

Pfizer said Tuesday it had started an early clinical trial of an experimental oral antiviral drug for Covid-19.

The New York-based company announced that the Phase 1 study of the drug PF-07321332 will be conducted in the United States. The drug belongs to a class of drugs called protease inhibitors, and it works by blocking an enzyme that the virus needs to replicate in human cells.

Protease inhibitors are used to treat other viral pathogens such as HIV and hepatitis C.

“Fighting the COVID-19 pandemic requires both preventive vaccination and targeted treatment of those who become infected with the virus,” Pfizer’s chief scientist Mikael Dolsten said in a press release. “Given the way SARS-CoV-2 is mutating and the ongoing global impact of COVID-19, it is likely that access to therapeutic options will be critical both now and after the pandemic.”

The study comes as Pfizer is also working on an intravenously administered protease inhibitor known as PF-07304814. This drug is currently in a Phase 1b clinical trial in patients hospitalized with Covid-19.

A person walks past the Pfizer building in New York City on March 2, 2021.

Carlo Allegri | Reuters

Pfizer already has an approved vaccine in the US with German drug maker BioNTech, but health experts say the world will need a slew of drugs and vaccines to end the pandemic that is infecting more than 29.8 million Americans and is coming soon Has killed at least 542,991 people over a year, according to the Johns Hopkins University.

Preclinical studies have shown that the oral drug, the first orally ingested protease inhibitor for Covid-19 to be studied in clinical trials, has “strong” antiviral activity against the virus.

Because the drug is taken orally, it can be used outside of hospitals for people newly infected with the virus. The researchers hope the drugs will prevent the disease from getting worse and keep people out of the hospital.

Pfizer said it will provide more details on the drug at the Spring American Chemical Society meeting on April 6.

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Business

How Anti-Asian Exercise On-line Set the Stage for Actual-World Violence

Negative Asian American tropics have long existed online, but increased in March last year when parts of the United States were locked down due to the coronavirus. This month, politicians like Republican Paul Gosar of Arizona and Republican Kevin McCarthy of California used the terms “Wuhan virus” and “Chinese coronavirus” to refer to Covid-19 in their tweets.

Then, according to a study by the University of California at Berkeley, those terms started trending online. On the day Mr. Gosar posted his tweet, the use of the term “Chinese virus” on Twitter increased 650 percent. A day later, consumption in conservative news articles rose 800 percent, the study found.

Mr. Trump posted eight times on Twitter in March last year about the “Chinese virus,” which is causing life-threatening reactions. In the response area of ​​one of his posts, a Trump supporter replied, “U caused the virus” and forwarded the comment to an Asian Twitter user who had quoted the US death statistics for Covid-19. The Trump fan added an arc about Asians.

In a study by the University of California at San Francisco this week, researchers who examined 700,000 tweets before and after Trump’s March 2020 posts found that people who posted the hashtag #chinesevirus were more likely to use racist hashtags, including #bateatingchinese.

“There has been a lot of discussion that the Chinese virus is not racist and can be used,” said Yulin Hswen, assistant professor of epidemiology at the University of California at San Francisco who conducted the research. But the term, she said, has evolved into a “rallying call to rally and motivate people who have these feelings and to normalize racist beliefs”.

Representatives from Mr. Trump, Mr. McCarthy and Mr. Gosar did not respond to requests for comment.

The misinformation linking the coronavirus to anti-Asian beliefs has also increased over the past year. According to Zignal Labs, a media literacy company, nearly eight million speeches against Asia have been published online since March last year, many of which are false.

Increasing attacks against Americans from Asia

    • Eight people, including six women of Asian origin, were killed in the gunfight at the Atlanta massage parlor. The suspect’s motives are being investigated, but Asian communities in the United States are on high alert as attacks against Asian-American citizens have increased over the past year.
    • In the early days of the coronavirus pandemic, a stream of hatred and violence against Americans from Asia began in the United States last spring. Community leaders say the bigotry was fueled by the rhetoric of former President Trump, who called the coronavirus the “China virus”.
    • A wave of xenophobia and violence in New York has been compounded by the economic fallout from the pandemic that dealt a severe blow to the Asian-American communities in New York. Many community leaders say racist abuse is overlooked by the authorities.
    • In January, an 84-year-old man from Thailand was violently beaten to the ground in San Francisco, leading to his death in a hospital two days later. The videotaped attack has turned into a rally.

In one example, an April article by Fox News that went viral for no reason indicated that the coronavirus was created and deliberately released in a laboratory in the city of Wuhan, China. The article was liked and shared more than a million times on Facebook and retweeted 78,800 times on Twitter. This is based on data from Zignal and CrowdTangle, a Facebook-owned tool for analyzing social media.

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Health

WHO scientist warns world is at ‘very dangerous’ stage as Covid instances rise

The world needs to step up its efforts to fight Covid-19 – and countries must not give up their vigilance, the World Health Organization’s chief scientist warned on Monday as coronavirus cases rise around the world.

“We are in a very risky phase,” said Dr. Soumya Swaminathan from the World Health Organization. “We have to double up, this is not the time to slack off.”

The WHO warned last week that the number of new Covid-19 cases is increasing with declines worldwide after six consecutive weeks. More than 2.6 million new cases were reported in the last week of February, a 7% increase from the previous week, according to the health department.

The Eastern Mediterranean, Southeast Asia, Europe and America all recorded increases of between 6% and 14%.

Although vaccines are on the rise for us in the nation, we cannot give up our vigilance.

Julie Morita

Robert Wood Johnson Foundation

“This is partly due to lockdown fatigue, you know. It’s because people … may loosen up believing vaccines are on the way,” Swaminathan told CNBC’s Squawk Box Asia on Monday. New variants could also play a role, she added.

“We have to … do everything we know to keep these viruses under control, keep transmission under control until we have enough vaccines,” she said, warning health systems could become overloaded again.

“Health workers around the world are exhausted, they have been battling it for over a year now,” she added.

Other health professionals have also suggested that it is not time to get complacent.

Julie Morita, executive vice president of the Robert Wood Johnson Foundation, said it was important to realize that infections, hospitalizations and deaths are still high even after falling from their peaks in the US

“It is still necessary that we wear our masks, social distance, avoid large crowds while we are vaccinated,” she told CNBC’s Street Signs Asia on Monday.

“Although vaccines are on the rise for us in the nation, we cannot give up our vigilance,” she said. “It’s way too early to relax.”

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Politics

For Biden, Deliberation and Warning, Perhaps Overcaution, on the World Stage

However, the first signs indicate that Mr Biden is moving more slowly on the world stage than he is at home. And that’s partly based on his belief, his national security adviser Jake Sullivan said in an interview, that the United States will only regain its global influence after taming the pandemic, restoring economic growth and resetting its relations with allies.

The most telling of his decisions concerns Saudi Arabia. After banning arms sales to stop what he described as a “catastrophic” war in Yemen, Mr Biden released an intelligence report on Prince Mohammed’s role in the assassination of dissident Jamal Khashoggi and imposed new sentences on the personal king of the Crown Prince Guard, the so-called Rapid Intervention Force. But Mr Biden stopped at the next step – apart from travel or the threat of criminal prosecution of the 35-year-old Crown Prince.

The president had not told staff in advance whether he would be in favor of direct action, despite saying in the campaign that the Saudi leadership had “no redeeming social value”.

Mr. Sullivan said he and his staff went to Mr. Biden with “a broad recommendation that recalibrating the relationship rather than breaking the relationship is the right course of action.”

Mr Biden, Mr Sullivan, said, “pushed us into our assumptions as he worked through the pros and cons of all aspects of the policy,” including the staff’s conclusion that the best way to do this was to keep a channel open for the Crown Prince . solve the war in Yemen. “

But the final decision was a reminder, other aides said, that Mr. Biden emerged from his three decades in the Senate with a belief in cultivating even the toughest of alliances – and a dose of realism that the United States couldn’t prevent the Crown Prince from doing, to become the next king.

“Unfortunately, every day we deal with heads of state and government who are responsible for actions that we find either offensive or disgusting, whether it is Vladimir Putin or Xi Jinping,” said Antony J. Blinken, undersecretary of state and the longest serving foreign policy advisor to Mr Biden, said on PBS NewsHour on Wednesday.

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World News

Biden Declares ‘America Is Again’ on Worldwide Stage: Dwell Updates

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Biden Returns to the International Stage

On Friday, President Biden spoke about the struggles of democracy and the importance of building close alliances with foreign leaders.

When I last spoke in Munich, I was a private citizen. I was a professor, not an elected official, but I said at that time, we will be back. And I’m a man of my word — America is back. I speak to you today as president of the United States at the very start of my administration, and I’m sending a clear message to the world: America is back, the trans-Atlantic alliance is back, and we are not looking backward. We are looking forward together. The global dynamics have shifted. New crises demand our attention. We cannot focus only on the competition among countries that threaten to divide the world or only on global challenges that threaten to sink us all together if we fail to cooperate. We must do both, working in lockstep with our allies and partners. So let me erase any lingering doubt. The United States will work closely with our European Union partners and the capitals across the continent.

On Friday, President Biden spoke about the struggles of democracy and the importance of building close alliances with foreign leaders.CreditCredit…Anna Moneymaker for The New York Times

For anyone looking for evidence that boasts about “America First” — and the need for America to go-it-alone — are over, President Biden’s speech to the Munich Security Conference was meant as an opening argument.

“America is back, the trans-Atlantic alliance is back,” Mr. Biden declared. Trying to expunge the last four years without ever once naming his predecessor, Donald J. Trump, Mr. Biden said “we are not looking backward.”

And then he went on to offer a 15-minute ode to the power of alliances.

He talked about an America that was itself overcoming challenges to the democratic experiment.

“We have to prove that our model isn’t a relic of history,” he said, a clear reference to the critique that China and Russia have been helping to push. “We must demonstrate that democracies can still deliver for our people in this changed world. That is our galvanizing mission. Democracy doesn’t happen by accident. We have to defend it. Strengthen it. Renew it.”

In sharp contrast to Mr. Trump, who declined on several occasions to acknowledge the United States’ responsibilities under Article V of NATO to come to the aid of allies, he said “We will keep the faith” with the obligation. “An attack on one is an attack on all.”

But he also pressed Europe to think about challenges in a new way — one that differs from the Cold War, even if the two biggest adversaries were familiar from that period.

“We must prepare together for long-term strategic competition with China,” he said, naming “Cyberspace, artificial intelligence and biotechnology” as the new subjects of competition, which he said he welcomed. The West must again be setting the rules of how these technologies are used, he argued, rather than ceding those forums to Beijing.

And he argued for pushing back against Russia — he called Vladimir V. Putin only by his last name, with no title attached — mentioning in particular the need to respond to the SolarWinds attack that was aimed at federal and corporate computer networks. “Addressing Russian recklessness and hacking into computer networks in the United States and across Europe and the world has become critical to protect collective security.”

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Boris Johnson Calls for G7 Cooperation on Global Threats

Boris Johnson, the British prime minister, hosted a virtual meeting with leaders of the Group of 7 nations on Friday and outlined the need for a multilateral approach to global vaccinations and the fight against climate change.

Around the world, make sure everybody gets the vaccines that they need so that the whole world can come through this pandemic together. I know that several colleagues have already announced that idea, and we in the U.K. strongly, strongly support it. And of course, we also want to work together on building back better from the pandemic, a slogan that I think that Joe has used several times. I think he may have nicked it from us, but I certainly nicked it from somewhere else — I think probably some U.N. disaster relief program — but we want to build back better from the pandemic. I think what we want to do with our plan is to ensure that the building back better, the green technology that we are going to use to tackle climate change, delivers the hundreds of thousands, if not millions, of new green-collar jobs that we know it can produce. Jobs and growth is what we’re going to need after this pandemic, and I think that the build back better operation offers the right way forward.

Video player loadingBoris Johnson, the British prime minister, hosted a virtual meeting with leaders of the Group of 7 nations on Friday and outlined the need for a multilateral approach to global vaccinations and the fight against climate change.CreditCredit…Daniel Leal-Olivas/Agence France-Presse — Getty Images

LONDON — Prime Minister Boris Johnson convened a video call of the leaders of the Group of 7 nations on Friday afternoon, seizing on the transition to a post-Trump world to push for greater global support and coordination to deliver coronavirus vaccines to billions of people in developing countries.

The call was part of a busy, if virtual, day of trans-Atlantic diplomacy that also featured the international debut of President Biden, who was set to deliver a foreign-policy address to the Munich Security Conference on Friday. Mr. Johnson and several other European leaders were also on the speaker lineup.

Multilateral cooperation — on the pandemic, climate change, and the Iran nuclear deal — was likely to be the watchword.

Whatever their lingering differences over Brexit or how to handle Russia and China, Mr. Johnson and other European leaders are eager to take advantage of an American president who wants to banish the “America First” policy of his predecessor, Donald J. Trump.

On the call, Mr. Johnson pledged that Britain would donate surplus supplies of vaccines to a program that will distribute doses in the developing world. Mr. Biden also confirmed that the United States will donate $4 billion to that effort over two years.

But even as the leaders pledged international cooperation, they faced very difficult situations at home. Mr. Johnson acknowledged as much in the video call, noting the Mr. Biden’s slogan — “Build Back Better” — had a familiar ring.

“I think he may have nicked it from us,” Mr. Johnson said laughing, “but I certainly nicked it from somewhere else — probably some U.N. disaster relief program.”

While Mr. Biden is clearly the star attraction, the video call was a major opportunity for Mr. Johnson, who vaulted himself into power by promising to deliver Britain’s departure from the European Union, to fashion a post-Brexit identity for his country as well.

In addition to Mr. Biden, the callers included Chancellor Angela Merkel of Germany, President Emmanuel Macron of France, Prime Minister Mario Draghi of Italy, Prime Minister Justin Trudeau of Canada, and Prime Minister Yoshihide Suga of Japan.

Mr. Johnson will play host to a summit meeting of the leaders in June at a seaside resort in Cornwall, in what would be their first face-to-face meeting in two years. The United States chaired the Group of 7 last year and was scheduled to host the meeting, but it was canceled because of the pandemic.

Even before the virus disrupted the gathering, Mr. Trump’s handling of it sowed dissent at home and abroad. He antagonized other leaders by inviting President Vladimir V. Putin of Russia to attend. And he kicked up a domestic political storm by steering the summit to his Trump National Doral golf resort in Miami.

Mr. Trump backed down, moving the meeting to Camp David, before it was scrapped entirely. His aides further inflamed matters by insisting that climate change would have no place on the agenda during Mr. Trump’s chairmanship.

Mr. Johnson, by contrast, was expected to make climate change a major theme in Friday’s call. Britain is also playing host to the United Nations’ climate change conference in Glasgow in November. It has announced ambitious emissions reduction targets that Mr. Johnson hopes will set the tone for the Glasgow conference.

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Merkel Calls for ‘Joint Strategy’ in Response to China and Russia

On Friday, Chancellor Angela Merkel of Germany called for the United States and Europe to reach a “joint agenda” for solving relations with China and Russia.

The trans-Atlantic partnership has two major tasks ahead of it, and we need a joint strategy to tackle that, and one of them is our relationship with Russia. When it comes to the sovereignty and territorial integrity of Ukraine, we have not really made any progress in recent years. The Minsk process is a diplomatic instrument that can be used, but it has not been successful. Russia has repeatedly caused hybrid conflicts that your states have been involved in. So we need a Russian agenda on Russia, a joint agenda. We must offer cooperation on the one hand. But on the other hand, we must be clear about the differences we have. And I can only agree with the U.S. president about the question of a strong European Union. The second thing, and that is more complex, we need a joint agenda with regard to China. China, on the one hand, is a competitor. But on the other hand, we need China to settle global problems such as climate change, biodiversity and others. In recent years, China has gained more power on the international stage. And we as a trans-Atlantic alliance and as Democratic countries need to react to that.

Video player loadingOn Friday, Chancellor Angela Merkel of Germany called for the United States and Europe to reach a “joint agenda” for solving relations with China and Russia.CreditCredit…Pool photo by Markus Schreiber

BERLIN — Chancellor Angela Merkel called for the United States and Europe to find a common approach to China and Russia, adding that she had “no illusions” that interests from either side of the Atlantic will always line up.

She made it clear that even though she welcomed President Biden’s overtures, Germany is no longer willing to simply follow Washington on the world stage.

Speaking after Mr. Biden on Friday, in what will most likely be her final appearance at the Munich Security Conference as German chancellor, Ms. Merkel welcomed the United States’ return to multilateral organizations after four years of former President Trump’s antagonism.

But as she listed the issues she viewed as the most pressing — from fighting terrorism in Africa to reviving stalled diplomatic talks in Ukraine — the German chancellor stressed that words alone will not be sufficient.

“It’s only actually good if you follow through,” Ms. Merkel said.

She called for Europe and the U.S. to align in dealing with Russia and China, which she said was “perhaps more complicated,” given China’s dual role as competitor and necessary partner for the West.

“In recent years, China has gained global clout, and as trans-Atlantic partners and democracies, we must do something to counter this,” Ms. Merkel said, stressing the pledges by both Germany and the U.S. to distribute vaccines in the developing world.

On Russia, she was more pointed.

“Russia continually entangles European Union members in hybrid conflicts,” she said. “Consequently it is important that we come up with a trans-Atlantic agenda toward Russia that makes cooperative offers on the one hand, but on the other very clearly names the differences.”

Ms. Merkel has been a regular at the conference since the early 2000s, before she was elected as Germany’s first female chancellor. In an uncharacteristically impassioned speech at the event in 2019, she rejected the demands of the Trump administration for Europeans to pull out of the Iran nuclear deal.

Germany remained in the agreement after the United States pulled out in 2018. Recent weeks have seen Iran grow increasingly bold, and in a call with President Hassan Rouhani of Iran on Wednesday, the chancellor made her government’s position clear that the deal should be preserved.

She “expressed concern that Iran was continuing to fail to meet its obligations under the nuclear agreement,” her office said in a statement and called on Iran to produce “positive signals that would build confidence and increase the chances of a diplomatic solution.”

On Friday she welcomed Mr. Biden’s decision to return to the agreement. “I hope that this agreement can be given another chance,” the chancellor said.

VideoVideo player loadingAt the Munich Security Conference on Friday, President Emmanuel Macron of France said Europeans and Americans need ‘effective multilateralism’ for climate, preserving democracies and protecting freedom of speech.CreditCredit…/EPA, via Shutterstock

PARIS — President Emmanuel Macron of France used a virtual appearance at the Munich Security Conference to make an impassioned defense of his concept of European “strategic autonomy,” arguing that it should not alarm the United States but would ultimately make NATO “even stronger than before.”

Speaking by video link after President Biden had addressed an upbeat “America-is-back” message to the conference, Mr. Macron made clear the postwar American-dominated world order needs to yield to new realities. He said Europe should be “much more in charge of its own security,” increasing its commitments to spending on defense to “rebalance” the trans-Atlantic relationship.

Speaking in English in answer to a question, he said the United States had spent decades “totally focused” on Europe but this had changed with the rising importance of Asia. “We must take more of the burden of our own protection,” the president said.

In practice, it will take many years for Europe to build up a defense arm that would make it more self-reliant. But Mr. Macron is determined to start now, just as he is determined to increase the European Union’s technological capacities so that it depends less on the United States or China.

Mr. Macron, who faces a presidential election in France next year, has made the need for “a sovereign Europe” a core theme. Other European countries, including Germany and Poland, worry about a weakening of the trans-Atlantic bond, which Mr. Biden clearly wants to restore and reinforce after the difficulties and provocations of the Trump years.

The rebuilding of NATO’S security architecture to face new challenges should involve “a dialogue with Russia,” Mr. Macron said. Given Mr. Biden’s firm tone on confronting President Vladimir V. Putin and restoring the territorial integrity of Ukraine, this apparently softer French line on relations with Russia suggested possible future tensions.

While France, like other European allies, has been delighted to see the end of the Trump era and has welcomed Mr. Biden, it has concluded that complete trust in the reliability of the United States is no longer a viable strategic option.

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U.S. Rejoins Paris Climate Agreement

President Biden told leaders of the Group of 7 nations that climate change was a priority for his administration as the United States formally rejoined the Paris climate agreement on Friday.

We can no longer delay or do the bare minimum to address climate change. This is a global existential crisis. And we’ll all suffer, we’ll all suffer the consequences if we fail. We have to rapidly accelerate our commitments to aggressively curb our emissions and to hold one another accountable for meeting our goals and increasing our ambitions. That’s why, as president, I immediately rejoined the Paris agreement. And as of today, the United States is officially, once again, a party to the Paris agreement, which we helped put together. On Earth Day, I will host a Leaders Summit to help drive a more ambitious actions among the top emitters, including domestic climate action here in the United States. I am grateful, I’m grateful for Europe’s continued leadership on climate issues over the last four years. Together, we need to invest in the technological innovations that are going to power our clean energy futures and enable us to build clean energy solutions to global markets.

Video player loadingPresident Biden told leaders of the Group of 7 nations that climate change was a priority for his administration as the United States formally rejoined the Paris climate agreement on Friday.CreditCredit…Stefani Reynolds for The New York Times

The United States on Friday formally rejoined the Paris climate agreement, the international accord designed to avert catastrophic global warming.

President Biden has said tackling the climate crisis is among his highest priorities and he signed an executive order recommitting the United States to the accord only hours after he was sworn into office last month.

“We can no longer delay or do the bare minimum to address climate change,” Mr. Biden said on Friday. “This is a global, existential crisis. And we’ll all suffer the consequences if we fail.”

It was a sharp repudiation of the Trump administration, which had pulled the country out of the pact and seemed eager to undercut regulations aimed at protecting the environment.

“The Paris Agreement is an unprecedented framework for global action,” Secretary of State Antony J. Blinken said in a statement on Friday. “We know because we helped design it and make it a reality.”

With some 189 countries joining the pact in 2016, it had broad international support and Mr. Biden’s move to rejoin the effort was welcomed by foreign leaders.

“Welcome back to the Paris Agreement!” Emmanuel Macron, the president of France, said in a Twitter message at the time.

The galvanizing idea of the Paris climate accord is that only global solidarity and collective action can prevent the ravages of climate change: hotter temperatures, rising sea levels, more powerful storms, or droughts leading to food shortages.

President Biden has announced a plan to spend $2 trillion over four years to increase the use of clean energies in transportation, electricity and building sectors, while rapidly moving away from coal, oil and gas. He has set a goal of eliminating fossil fuel emissions from electricity generation by 2035 and has vowed to put the entire United States economy on track to become carbon neutral by midcentury.

Former President Trump had announced in 2017 that the United States would withdraw from the Paris agreement, but the exit could not be made official until Nov. 4 last year.

The United States was officially out of the agreement for 107 days.

On Friday, Mr. Blinken said fighting climate change would be once again at the center of U.S. domestic and foreign policy priorities.

“Climate change and science diplomacy can never again be ‘add-ons’ in our foreign policy discussions,” Mr. Blinken said.

But, he added, “as momentous as our joining the agreement was in 2016 — and as momentous as our rejoining is today — what we do in the coming weeks, months, and years is even more important.”

Since the start of the industrial era, the United States has emitted more greenhouse gases than any other country. And so, how the United States uses its money and power has both a symbolic and real bearing on whether the world’s roughly 7.6 billion people, and especially its poorest, will be able to avert climate catastrophes.

There are two immediate signals to watch for. First, how ambitious will the Biden administration be in its emissions reductions targets? It is under pressure from advocacy groups to reduce emissions by 50 percent by 2030, compared to 2005 levels.

And second, how much money will the United States provide to help poor countries adapt to the calamities of global warming and shift their economies away from fossil fuels?

The answers to both are expected in the next few weeks, in time for the April 22 virtual climate summit that President Biden has said he will host.

President Joe Biden’s speech to the Munich security forum is expected to be broad in scope, those who have seen it say.Credit…Doug Mills/The New York Times

As a senator and as vice president, Joe Biden was one of the few people in Washington who actually enjoyed summit meetings — and was eager to show up at the Munich Security Conference, the meeting of Europe’s diplomatic and defense elites.

Two years ago he even showed up in Munich as a private citizen — one who was already running for president — backslapping his way through the jammed Hotel Bayerischer Hof, where the event is always held, and assuring allies that the Trump era would end, some day.

On his return on Friday, there was no glad-handing as the event was being held virtually and Mr. Biden spoke by video link. But his message was clear. The Trump era of “America first” diplomacy is over.

For all the violence and tumult in Washington in recent months, autocracies will never outperform democracies, and restored alliances are the West’s pathway to restored influence. He chastised China and warned Europe about the need to push back hard on Vladimir V. Putin’s Russia.

For the Europeans, dealing with Mr. Biden will be like putting on a pair of well-worn shoes — they know just what it will feel like. But Mr. Biden, some aides acknowledge, will also face more than a few doubters, who wonder whether his presidency will be just a brief alliance-friendly interregnum, and that the era of America First has not been extinguished.

His speech to the Munich security forum was broad in scope, arguing that the United States and its European allies can take on China without descending into a Cold War, and that the only way to deal with Russia is to push back hard against Mr. Putin.

He listed the treaties and multinational institutions that the United States has re-entered or re-engaged with in recent weeks, from the Paris agreement on climate change to the World Health Organization to Covax, the public-private effort to distribute vaccines around the world equitably.

On Thursday night, just before the speech, the State Department issued its first road map for re-entering talks with Iran for the first time in four years. It marked the first time since early 2018 that Europe and the United States were on the same page on an Iran strategy.

In public this will all generate applause; European leaders are just happy, they say, to go to a meeting without fear that the United States will be hinting it is getting ready to depart from the NATO alliance.

But Europeans, Mr. Biden’s aides concede, do not have the same view of China and the threat posed by its economic dominance and political influence. And the dependence of European countries on Russian energy supplies limits their enthusiasm for joining Mr. Biden in declaring that Mr. Putin will pay a price for undermining democracies.

Ursula von der Leyen, a top European Union’s official, speaks on Friday by video link during the Munich Security Conference.Credit…EPA, via Shutterstock

BRUSSELS — The European Union has largely set the regulatory framework for the chaos of the internet.

On Friday, a top official of the bloc, Ursula von der Leyen, president of the European Commission, called for the United States to join Europe “in creating a digital economy rule book valid worldwide, a set of rules based on our values.”

Ms. von der Leyen, speaking at the Munich Security Conference, cited the storming of the United States Capitol on Jan. 6 as “a turning point for our discussion of the impact social media has on our democracies.”

It was only a “short step from crude conspiracy theories to the death of police officers,” she said.

Regulating the power of big tech companies would be “an important step” in stopping political violence, she insisted, adding: “We want clear requirements that internet firms take responsibility for the content they distribute, promote and remove.”

Decisions on content must not be left to computer programs or to “the boardrooms of Silicon Valley,” she said. They must be made by democratically elected legislators, an argument France has consistently made.

GLOBAL ROUNDUP

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W.H.O. Warns of Unequal Vaccine Distribution

The World Health Organization on Friday warned that the unequal distribution of vaccines across the globe could further the spread of the coronavirus.

We need a new treaty if we’re serious enough about pandemics. And that will really help and prepare the world for the future. But the key is working together, considering the world as a small village, very much interconnected, and looking inwards wouldn’t help. And we should cooperate. And we have learned this lesson the hard way, by the way. And it’s a must to cooperate and it’s a must to take attention, to give attention to solidarity. Vaccine equity is not just the right thing to do. It’s also the smart thing to do. The longer it takes to suppress the virus everywhere, the more opportunity it has to change in ways that could make vaccines less effective and opportunity to mutate. We could end up back at square one.

Video player loadingThe World Health Organization on Friday warned that the unequal distribution of vaccines across the globe could further the spread of the coronavirus.CreditCredit…Christopher Black/Agence France-Presse — Getty Images

Dr. Tedros Adhanom Ghebreyesus, the director general of the W. H.O., on Friday urged countries and drugmakers to help speed up the manufacture and distribution of vaccines across the globe, warning that the world could be “back at square one” if some countries went ahead with their vaccination campaigns and left others behind.

“Vaccine equity is not just the right thing to do, it’s also the smartest to do,” Dr. Tedros said at the Munich Security Conference, arguing that the longer it would take to vaccinate populations in every country, the longer the pandemic would remain out of control.

Wealthy countries have come under increased criticism in recent weeks for stockpiling doses, and keeping them away from low- and middle-income countries. Dr. Tedros used his comments to condemn the approach to public health in many countries, which he called “a failure even in the most advanced economies in our world.”

“It affects everything, and the whole world is now taken hostage by a small virus,” he said.

Speaking before Mr. Ghebreyesus, Bill Gates, the billionaire philanthropist, said that the tragedy now unfolding across the world because of the pandemic could have been largely avoided.

“It is a tragedy that the modest steps that would have been required to contain this epidemic were not taken in advance,” he said.

While Dr. Tedros welcomed new commitments from wealthy countries to fund international vaccine efforts, he said more needed to be done, and faster.

United Nations Secretary General António Guterres, who also spoke before Mr. Ghebreyesus, said more than 100 countries had not received a single dose, and humanitarian groups have urged the public-private health partnership leading the international vaccine effort, known as Gavi, the Vaccine Alliance, to start delivering on its promises.

“While the Covax mechanism is designed specifically for equitable distribution and vaccine development, it has yet to deliver a single vaccine to a country,” says Claire Waterhouse, a South Africa-based advocacy coordinator for Doctors Without Borders.

More than 190 million people have been vaccinated worldwide, but almost none in Africa. Bodies have piled up on the streets in Bolivia, while in Mexico, oxygen shortage has led many to die at home.

In other news around the world:

  • The authorities in Madrid announced on Friday the lifting of travel restrictions in 31 areas of Spain’s capital region, as coronavirus cases fall. The decision means that, as of Monday, just over one-tenth of the almost 7 million residents of the Madrid region will remain in areas where they are not allowed to leave, except under special circumstances. Antonio Zapatero, a Madrid health official, said on Friday that the daily number of registered cases in Madrid was now down 35 percent from a week earlier and over 50 percent from two weeks earlier. Madrid is also easing its nighttime curfew, with bars and restaurants allowed to stay open until 11 p.m. rather than 9 p.m.

  • In recent months, Russia has scored a sweeping diplomatic win from an unexpected source: the success of its coronavirus vaccine, Sputnik V. So far, more than 50 countries from Latin America to Asia have ordered 1.2 billion doses of the Russian vaccine, buffing the image of Russian science and lifting Moscow’s influence around the world. Yet in Russia things are not always what they seem, and this apparent triumph of soft-power diplomacy may not be all that the Kremlin would like the world to think. While Sputnik V is unquestionably effective, production is lagging, raising questions about whether Moscow may be promising far more vaccine exports than it can supply, and doing so at the expense of its own citizens.

  • The Vatican has clarified that employees who refuse a coronavirus vaccine will not be punished, after pushback over an internal decree suggesting that those who did not get vaccinated could be dismissed. Vatican City State said in a statement on Thursday that “alternative solutions” would be found for employees who did not want to be vaccinated. That came in response to a heated debate over a Feb. 8 directive signed by Cardinal Giuseppe Bertello, the governor of the world’s smallest state. It referred to provisions in a 2011 law for Vatican employees stating that any who refuse preventive health measures can be punished, up to “the interruption of the relationship of employment.”

  • A Thailand hotel guest who posted complaints online faces the threat of a defamation charge. Topp Dunyawit Phadungsaeng spent 14 days in coronavirus quarantine at the Ambassador City Jomtien Hotel after arriving last month from San Francisco. On Monday, after checking out, he posted on Facebook about his stay, including 46 photographs and four videos that he took of the hotel, a government-designated quarantine facility. His posts were widely shared, especially a photo of what he said were the legs of a cockroach in his stir-fried meal. A day after his post appeared, the hotel issued a statement calling on a “certain group of people” to stop posting “false information” with the intent of damaging the hotel’s reputation. Otherwise, the hotel said, it had the right to pursue civil and criminal charges “to the utmost.”

President Biden delivering remarks at the White House last month on the fight to contain the pandemic. Credit…Doug Mills/The New York Times

An international effort to speed up the manufacture and distribution of coronavirus vaccines around the globe has gotten a boost.

On Friday, during a virtual meeting with other leaders from the Group of 7 nations, President Biden said that his administration would make good on a U.S. promise to donate $4 billion to the global vaccination campaign over the next two years. Other leaders also announced pledges, and at the end of the meeting, the European Union’s chief executive said that new commitments from the E.U., Japan, Germany and Canada had more than doubled the G7’s total support to $7.5 billion.

The World Health Organization released a statement welcoming the additional pledges for the campaign, known as Covax, and noting that commitments for the program now total $10.3 billion — but also saying that a funding gap of $22.9 billion remained for the campaign’s work this year.

The Covax effort has been led by the public-private health partnership known as Gavi, the Vaccine Alliance, as well as the Coalition for Epidemic Preparedness Innovations and the World Health Organization. It aims to distribute vaccines that have been deemed safe and effective by the W.H.O., with a special emphasis on providing them to low- and middle-income countries.

Public health experts often say that unless everyone is vaccinated, it’s as if no one is vaccinated.

So far, the United States has pledged more money than any other nation, with at least one official noting that diminishing the pandemic’s global impact would benefit the country’s own economy and security. White House officials said the money would be delivered in multiple tranches: an initial donation of $500 million right away, followed shortly by an additional $1.5 billion. The remaining $2 billion will delivered by the end of 2022. The funds were approved last year by a Republican-led Senate when President Donald J. Trump was still in office.

President Biden’s engagement in the global fight against the pandemic stands in stark contrast to the approach of Mr. Trump, who withdrew from the World Health Organization and disdained foreign assistance, pursuing a foreign policy he called “America First.” Mr. Biden rejoined the World Health Organization immediately after taking office in January.

National security experts have said the United States should consider donating vaccine doses to poorer countries, as India and China are already doing in an effort to expand their global influence. But an official said that the U.S. would not be able to share vaccines while the American vaccination campaign is still continuing to expand.

The global vaccination effort also stands to benefit from a commitment by the pharmaceutical company Novavax, whose coronavirus vaccine is still in trials.

Under a memorandum of understanding between Gavi and Novavax, the company agreed to provide “1.1 billion cumulative doses,” though it did not specify a time frame. The vaccine will be manufactured and distributed globally by Novavax and the Serum Institute of India, the world’s largest vaccine manufacturer.

Novavax is expected to provide vaccines primarily to high-income countries, the company said in its announcement, while the Serum Institute will supply “low-, middle, and upper-middle-income countries,” using “a tiered pricing schedule.”

Novovax recently reported that its vaccine showed robust protection in a large British trial, but was less effective against the variant of the virus first identified in South Africa. Trials are also underway in the United States, Mexico and the United Kingdom.

President Emmanuel Macron is shown speaking via video link at the Munich Security Conference.Credit…Pool photo by Thibault Camus

Two weeks after President Biden’s inauguration, Emmanuel Macron, his French counterpart, spoke publicly about the importance of dialogue with Moscow, saying that Russia is a part of Europe that cannot simply be shunned and that Europe must be strong enough to defend its own interests.

On Dec. 30, just weeks before the inauguration, the European Union clinched an important investment agreement with China, days after a tweet by Mr. Biden’s national security adviser, Jake Sullivan, asking for “early consultations” with Europe on China and seeming to caution against a quick deal.

So even as the United States resets under new White House leadership, Europe is charting its own course on Russia and China in ways that do not necessarily align with Mr. Biden’s goals, posing a challenge as the new American president sets out to rebuild a post-Trump alliance with the continent.

Speaking at the Munich Security conference two years ago, Mr. Biden lamented the damage the Trump administration had inflicted on the once-sturdy postwar relationship between Washington and Europe’s major capitals. “This too shall pass,” Mr. Biden said. “We will be back.” He promised that the United States would again “shoulder our responsibility of leadership.”

The president’s remarks on Friday are sure to repeat that promise and spotlight his now-familiar call for a more unified Western front against the anti-democratic threats posed by Russia and China. In many ways, such talk is sure to be received like a warm massage by European leaders shellshocked by four years of President Donald J. Trump’s mercurial and often contemptuous diplomacy.

But if by “leadership” Mr. Biden means a return to the traditional American assumption — we decide and you follow — many Europeans feel that world is gone, and that Europe must not behave like America’s junior wingman in fights defined by Washington.

Demonstrated by the European Union’s trade deal with China, and conciliatory talk about Moscow from leaders like Mr. Macron and Germany’s likely next chancellor, Armin Laschet, Europe has its own set of interests and ideas about how to manage the United States’ two main rivals, ones that will complicate Mr. Biden’s diplomacy.

“Biden is signaling an incredibly hawkish approach to Russia, lumping it in with China, and defining a new global Cold War against authoritarianism,” said Jeremy Shapiro, the research director at the European Council on Foreign Relations.

That makes many European leaders nervous, he said. And other regional experts said they had seen fewer signs of overt enthusiasm from the continent than Biden administration officials might have hoped for.

“There was always a cleareyed recognition that we weren’t just going to be able to show up and say, ‘Hey guys, we’re back!’” said Andrea Kendall-Taylor, who was in line to become the National Security Council director for Russia but who did not take the job for personal reasons.

Iran’s economy has been severely damaged by Trump era sanctions, and Tehran is insisting on their removal before negotiations can begin.Credit…Majid Asgaripour/Wana News Agency, via Reuters

On the eve of a virtual summit of world leaders on Friday, the United States took a major step toward restoring the Iran nuclear deal that the Trump administration abandoned, offering to join European nations in what would be the first substantial diplomacy with Tehran in more than four years, Biden administration officials said.

In a series of moves intended to make good on one of President Biden’s most significant campaign promises, the administration also backed away from a Trump administration effort to restore United Nations sanctions on Iran. That effort had divided Washington from its European allies.

And at the same time, Secretary of State Antony J. Blinken told European foreign ministers in a call on Thursday morning that the United States would join them in seeking to restore the 2015 nuclear accord with Iran, which he said “was a key achievement of multilateral diplomacy.”

Hours later, Enrique Mora, the European Union’s deputy secretary general for political affairs, appealed to the original signers of the nuclear deal — Britain, France, Germany, Russia and China — to salvage it at “a critical moment.”

“Intense talks with all participants and the US,” Mr. Mora said on Twitter. “I am ready to invite them to an informal meeting to discuss the way forward.”

While it was unclear whether the Iranians would agree to join discussions, three people familiar with the internal debate said it was likely Iran would accept. The officials said Iran would probably be more open to a meeting with the European Union, where the United States was a guest or observer, rather than direct formal talks with Washington as a participant.

In recent days, the Iranian foreign minister, Mohammad Javad Zarif, and President Hassan Rouhani have suggested they were open to discussing some kind of synchronized approach, in which both sides would act on a certain date. That has an appeal inside the White House, one senior American official said, noting it was how key steps for carrying out the original 2015 deal were coordinated.

But with an Iranian presidential election only four months away, it was not clear if the country’s supreme leader, Ayatollah Ali Khamenei, and the nation’s political and military leadership would fully support re-engagement with the United States.

Categories
Politics

Biden Takes Middle Stage With Bold Agenda as Trump’s Trial Ends

WASHINGTON – President Biden’s allies say that after the impeachment process of his predecessor is distracted, he will be quick to press for the passage of his $ 1.9 trillion coronavirus relief plan before moving on to an even bigger agenda in Congress that is Infrastructure, immigration and crime includes judicial reform, climate change and health care.

Mr Biden has so far been able to move his agenda forward amid the whirlwind of impeachment, trial and acquittal of former President Donald J. Trump. House committees are already debating parts of the coronavirus relief laws he calls the American Rescue Plan. Despite the Trump drama, several president’s cabinet members were confirmed. And Mr Biden’s team urges lawmakers to act swiftly when the senators return from a week-long hiatus.

Without the spectacle of constitutional conflict, the new president “is now center stage in a way the first few weeks did not allow,” said Jennifer Palmieri, who served as communications director for President Barack Obama. She said the end of the process means “2021 can finally begin”.

In a post-trial statement, Mr. Biden reiterated his hopes for bipartisan support and pledged to work bipartisan to “heal the soul of the nation.” However, Mr Biden’s outlook is compounded by the fact that much of his agenda is aimed at dismantling Mr Trump’s policies or addressing what Democrats have viewed as his failure, especially the fiddled response to the pandemic.

And the 43 “not guilty” Senate Republican votes on Saturday have greatly eased both political opportunities and challenges for Mr Biden: a small minority of Republican senators willing to brave the wrath of Mr Trump’s powerful political movement by voting condemn him while Mr Trump continues to rule most of his party.

The reality is that Mr Trump’s influence over Republicans will be an obstacle to Mr Biden’s priorities even if the former President leaves Washington. Even with control of both Houses of Congress, the Democrats will still need Republican support on many of Mr Biden’s agenda items to overcome a filibuster in the Senate.

“Trump will certainly continue to be a force in the Republican Party. They have to decide whether or not they are trapped, ”said Winnie Stachelberg, executive vice president at the Center for American Progress, a liberal think tank. “President Biden is focused on the welfare of the American people. He will not be derailed and distracted from this main mission, whatever the sideshow former President Trump does. “

In the past few days, senior members of Mr Biden’s team have started internal meetings at the White House to discuss what the next phase of his agenda will be and how it will be implemented, according to two senior White House advisers. Some of this could be publicly announced in March, if Mr Biden is expected to deliver a joint address to Congress, as is the custom in the first year of a president’s office.

Administration officials acknowledge that Mr Biden will now receive more public attention, a reality they plan to capitalize on with the President’s first substantive trip outside Washington earlier this week. Mr Biden will attend a CNN town hall-style event in Milwaukee on Tuesday and travel to another part of the country on Thursday.

“For understandable reasons, it will be more of a spotlight than it was last week,” said Jen Psaki, White House press secretary. “Now there may be a focus on the president’s agenda again, getting relief into the hands of the American people.”

Public polls show that the president’s agenda is widespread even among some Republicans. This has added pressure from Democratic progressives to refrain from compromising with Republicans that could water down Mr Biden’s political proposals. And the Republicans, still bracing for the loss of the Senate and White House, have not yet banded together in a rigorous substantive assault on the president’s agenda.

“He might be able to get more country on his side when it comes to supporting the agenda as there is no cohesive Republican argument,” said Ms Palmieri of Mr Biden.

Given the razor-thin margins in Congress, the president’s hopes for a swift implementation of an ambitious agenda are more likely if he can at least count on the support of Republicans. And Mr Trump’s influence on the party threatens the prospect of cross-party cooperation.

For the first 24 days of Mr Biden’s presidency, Mr Trump had a constant presence – not on the Twitter account he is banned from using, but as an impeachment target to spark a riot to prevent his own fall. Reporters encamped in Palm Beach, Florida as wall-to-wall cable networks covered the Senate trial that would determine its fate.

Mr Biden tried to distance himself from the debate over whether Mr Trump should be held accountable for the January 6 uprising in the Capitol for fear it would lose momentum on his agenda.

Even when the process is over, Mr Trump seems unwilling to lose sight of the nation’s psyche. Former President aides say Mr Trump plans to hold a press conference from Mar-a-Lago, his home in Florida, in the coming days. In a statement immediately after the trial ended, Trump, who has expressed an interest in running for president again in 2024, indicated that he had no plans to disappear from television screens or from the political life of Republicans in Congress.

“Our historic, patriotic and beautiful movement to make America great again has only just begun,” wrote the former president. “I have a lot to share with you in the months ahead, and I look forward to continuing our incredible journey together to achieve American greatness for all of our people. There has never been anything like it! “

Ms Psaki said the president, who steadfastly refused to comment on the ongoing impeachment process, is not focusing on Mr Trump. She said that mentions of his comments or activities were very rare in private conversations between the president and his aides.

“The political campaign is over,” she said. “He hit Donald Trump. He and we don’t want to get involved in this fight again. “

Presidents often refer to their predecessors long after leaving the world’s largest bullying pulpit.

When Mr. Obama took office in 2009, he vowed to end his predecessor George W. Bush’s “cowboy diplomacy” and blamed him for the country’s economic problems. In 2017, Mr Trump repeatedly downgraded Mr Obama’s performance to encourage the change he felt was necessary.

But perhaps more than any other past president, Mr Biden has used Mr Trump as an effective political slide, constructing his agenda almost entirely as a rejection of Mr Trump’s politics and personal conduct during his turbulent four years in office.

Mr Biden’s first actions on Day 1 were a flash of executive orders designed to undo many of Mr Trump’s policies in a single day. And he often sees his broader agenda as the necessary response to actions his predecessor took or not taken. Late last week, he said again that Mr Trump’s administration had failed to provide the government with tools to fight the coronavirus pandemic.

“What we thought was available, from vaccine to vaccine, was not the case,” Biden told a non-partisan group of mayors and governors.

Joe Lockhart, who served as press secretary for President Bill Clinton, said the most important thing Mr Biden can do to advance his broad agenda is successfully fighting the pandemic and working to repair the troubled economy.

“Where he will gain political capital is to compare his handling of the pandemic to the disastrous efforts of the Trump administration,” Lockhart said. The end of impeachment, he said, “paves the way for people to focus on it.”

The question for Mr Biden is whether he can use the political space to build support for his proposals. And if he can, will public pressure be enough to convince Republicans in Congress to oppose Mr. Trump’s influence?

Senator Chris Coons, Democrat of Delaware and a close ally of the president, said Mr Biden would continue to push for bipartisan collaboration on coronavirus relief law and other priorities. But he said he was confident the president would not be put off by the Republican opposition.

“He’s making strides in the relief backed by three-quarters of the American people,” Coons said on ABC’s This Week on Sunday. “And from the way he spoke when he was inaugurated, to the actions he took in the first few weeks, he shows us what real presidential leadership looks like in sharp contrast to his predecessor.”

Categories
Health

‘Zero Covid’? We’re not at that stage but, WHO says

A nurse prepares the Pfizer BioNTech Covid-19 vaccine on January 10, 2021 at a vaccination center in Sarcelles near Paris.

ALAIN JOCARD | AFP | Getty Images

LONDON – As coronavirus vaccines continue to roll out in major economies around the world, attention is again turning to current lockdown strategies to eradicate new cases of the virus.

Some experts have called for a “zero-covid” strategy that advocates very strict lockdowns, social restrictions and travel bans to eradicate all cases of the virus before public and business life can be reopened.

Countries like New Zealand and Australia have adopted this approach, closing their countries early in the pandemic to prevent new cases. Citing their success in containing the pandemic, some experts in Ireland are also advocating a “zero-covid” approach, although given Northern Ireland’s open border with the rest of the UK, there is disagreement on whether such a policy would work there

On Thursday, World Health Organization experts said it was too early and difficult in practice to consider a “zero-covid” approach.

“Elimination is basically something we want for every disease, for every pathogen, and it can be a very powerful incentive to work. But whether we’re at the stage now – setting goals for a zero-covid strategy – is still open another ball game, “said Dr. Hans Henri P. Kluge, WHO Regional Director for Europe, at a press conference on Thursday.

“First and foremost, we need to see how people’s behavior, how they adhere to non-pharmaceutical interventions, adds up to the timing of policy decisions when vaccination is introduced, and how the pandemic is brought under control.”

Zero Covid strategies were based on banning inbound travel, but some countries were easier to restrict or “isolate from international travel” than others, Kluge said. Many countries in Europe have banned all but essential travel during the lockdown. Forced hotel quarantines for travelers to the UK are now on the horizon, despite critics saying the move is too little and too late.

The introduction of vaccinations is creating a silver lining for lockdowns and, along with restrictions on public life, has slowly seen a decline in new cases and hospital admissions.

Kluge said the European region, which includes 53 countries for WHO, has seen a decrease in new cases in the past four weeks and deaths in the past fourteen days. Still, more than 1 million cases have been reported in the European region every week, Kluge said, and the spread of new variants remains a major problem.

Vaccine manufacturers are already working on second generation footage to target variants of the virus. Concern and caution about mutations are causing governments to be on the alert when it comes to lifting bans.

On the one hand, Germany extended its lockdown until the beginning of March amid concerns about the spread of a variant first discovered in Great Britain. With this variant, which according to the WHO has now been reported in more than 80 countries, a leading British scientist said it was on the right track, “most likely to sweep the world”.

Unlocking “must be gradual and safe,” said Kluge, adding, “the biggest mistake is lowering our guard (too early).”

Dr. Catherine Smallwood, chief emergency officer on WHO’s Europe team, said the virus would take advantage of easing restrictions too early.

“This virus is going to take every chance we give it to spread quickly, and it’s going to spread much faster than we think. … Every time we lift a restriction, every time we do, it will open a part of our society that balance towards the favor of the virus. “

She warned that transmission rates would remain high and that lowering the transmission rates would aid vaccination programs.

Categories
Business

The New Yorker Journal Union Workers Stage Daylong Walkout

The New Yorker’s union employees didn’t go to work Thursday.

The New York Union’s 100+ employees, which include fact checkers, web producers and a few other editorial staff, opted for the full-day strike after recent rounds of negotiations with management failed, said Natalie Meade, chairwoman of the union.

The problem is the payment. Ms. Meade, a fact-checker for the magazine, said the union wants to raise the minimum wage to $ 65,000. In recent negotiations, The New Yorker executives failed to hit that number and instead offered pay hikes that they described as “offensive”.

“They already know they are underpaying us,” said Ms. Meade.

The union, which does not represent the authors of the New York employees, has been working on a collective agreement since 2018. The strike started at 6 a.m. on Thursday and was supposed to last 24 hours.

Before the negotiations, the union conducted a salary study based on data from Condé Nast, the magazine’s parent company. The survey found that union workers at The New Yorker had an average salary of $ 64,000 and that the company’s editorial assistants received an average salary of $ 42,000.

In a statement on Thursday, a New York spokesman said that salary proposals made during recent rounds of negotiations were “initial offers”.

“We hope that, contrary to measures like this, the union will negotiate in good faith and return a counter-proposal, as is customary in negotiations,” the statement said. “This way we can work productively together to get a final contract as quickly as possible.”

The New York spokesman also criticized the union’s wage study, adding, “We are committed to fair pay. We dispute certain conclusions of this study and are determined to reach a fair agreement. “

In September, Senator Elizabeth Warren, Democrat of Massachusetts, and Representative Alexandria Ocasio-Cortez, Democrat of New York, withdrew from the New York Festival’s keynote speaker slots in solidarity with union workers planning a digital picket line for print management for a “just cause” to be included in their agreement.

“Just Reason” is a provision often found in union contracts that sets a standard that employers must adhere to in order to discipline disciplinary or fire service workers. New York management eventually agreed to include it.

The New York Union is part of the NewsGuild of New York, which represents employees of the New York Times, Reuters, The Daily Beast, and other news outlets.

Categories
World News

E.U. Company Approves Pfizer Vaccine, Setting Stage for Excessive-Stakes Rollout

BRÜSSEL – Von Stockholm bis Athen und von Lissabon bis Warschau bereiten sich die Regierungen der Europäischen Union darauf vor, später in dieser Woche einen Coronavirus-Impfstoff zu erhalten, auch wenn in einigen Teilen des Kontinents immer mehr Fälle auftreten.

Die Drogenbehörde des Blocks, die Europäische Arzneimittel-Agentur, genehmigte am Montag den Pfizer-BioNTech-Impfstoff und startete einen logistischen Marathon, mit dem sich die meisten Behörden in der Region bisher nicht auseinandersetzen mussten.

Die Operation zum Kauf, zur Genehmigung und zur Verteilung der Schüsse in der gesamten Europäischen Union war komplex und politisch aufgeladen, und die Einsätze könnten nicht höher sein. Die zweite Welle der Pandemie tobt immer noch in Teilen der Region, die meisten Europäer verbringen die Ferien in einer Art Sperrung, und die Volkswirtschaften des Blocks sind in Trümmern.

Um die Sache noch komplizierter zu machen, führte eine hoch ansteckende Variante in England viele europäische Länder am Wochenende dazu, Reisende aus Großbritannien zu blockieren, obwohl Wissenschaftler sagen, dass sie den Kontinent bereits erreicht haben.

Wenn die Impfstoffmission erfolgreich ist, kann sie die Glaubwürdigkeit der Europäischen Union stärken und ihre Verwaltung als eine echte Kraft mit Exekutivbefugnissen und Fähigkeiten etablieren, die wichtige Aufgaben im Namen ihrer Mitglieder übernehmen können. Wenn nicht, kann der Fehler Schärfe und Unzufriedenheit verbreiten.

Die Europäische Arzneimittel-Agentur wurde eingehend auf das Tempo geprüft, mit dem sie den Pfizer-BioNTech-Impfstoff überprüfte. Großbritannien erteilte vor Wochen die Impfstoff-Notfallgenehmigung und begann dann mit der Einführung seines Impfprogramms, wobei die Vereinigten Staaten nicht weit dahinter folgten.

Am Ende beschloss die Europäische Agentur, den Prozess zu beschleunigen und ein für den 29. Dezember angesetztes Zulassungstreffen voranzutreiben. Die Vereinigten Staaten haben auch einen Impfstoff von Moderna zugelassen, aber die Europäische Agentur wird den Antrag auf Zulassung nicht bearbeiten von den Aufnahmen dieser Firma bis zum 6. Januar.

Nachdem die Agentur den Pfizer-BioNTech-Impfstoff zugelassen hat, wird erwartet, dass die Europäische Kommission, die Exekutive der Europäischen Union, die Entscheidung innerhalb von 48 Stunden stempelt. Dies wäre grünes Licht für Pfizer, um Impfstoffe in der Region zu verteilen.

Die Kommission übernimmt die Verantwortung für diese erste Ladung, da die Fracht die Pfizer-Fabriken in Puurs (Belgien) und Mainz (Deutschland) verlässt und höchstwahrscheinlich am Donnerstag in Richtung europäischer Hauptstädte fährt. Das Unternehmen, das sich aus Sicherheitsgründen weigerte, detaillierte Fragen zu Transportplänen zu beantworten, wird in jedem Land eine aktive Rolle beim Transport und der Lagerung von Impfstoffen spielen.

Von diesem Zeitpunkt an wird jede der 27 Mitgliedsregierungen des Blocks dafür verantwortlich sein, den Impfstoff auf eine Weise an die Bevölkerung zu verteilen, die den Bedürfnissen, Prioritäten und Fähigkeiten jedes Landes entspricht.

Die ersten Europäer werden voraussichtlich am 27., 28. und 29. Dezember geimpft.

Der Druck, dies richtig zu machen und dies schnell zu tun, hat zugenommen, als die Europäische Union und ihre Mitglieder einen kollektiven Ansatz in einem kritischen Knotenpunkt im Kampf gegen die Pandemie versuchen. Die meisten Länder waren nationalistischer.

Der europäische Ansatz begann mit der Entscheidung in diesem Sommer, das Verhandlungskapital zu bündeln und die Europäische Kommission und einen Vorstand aus allen Mitgliedsländern zu ermächtigen, Vereinbarungen mit Pharmaunternehmen zu treffen, die an Impfstoffen arbeiten.

Es wurde kritisiert, dass die Europäische Union wie die Vereinigten Staaten nicht genügend Dosen des Pfizer-BioNTech-Impfstoffs bestellt hat, als ihnen eine Chance gegeben wurde. Aus finanzieller Sicht scheint der Ansatz jedoch dem Block zugute gekommen zu sein: Der Pfizer-BioNTech-Impfstoff zahlt weniger als die USA.

In Deutschland, der größten Volkswirtschaft des Blocks und Heimat von BioNTech, wurde die Entscheidung, die Europäische Kommission zur Aushandlung eines Abkommens zu ermächtigen, kritisiert, und einige argumentierten, dass das Land besser dran gewesen wäre, es alleine zu machen. Aber die meisten Blockmitglieder sind mittelgroße Länder oder kleiner, und für sie war der Ansatz sinnvoll. (Wenn die Zeit bis zum Brexit läuft, sehen einige hier möglicherweise auch eine starke politische Botschaft, wobei der Block zeigt, dass die Einheit stark ist.)

Wenn der Prozess bis zu diesem Punkt vereinheitlicht wurde, sieht der Rollout nun von Land zu Land ganz anders aus.

Covid19 Impfungen >

Antworten auf Ihre Impfstofffragen

Mit der Verbreitung eines Coronavirus-Impfstoffs ab den USA finden Sie hier Antworten auf einige Fragen, über die Sie sich möglicherweise wundern:

    • Wenn ich in den USA lebe, wann kann ich den Impfstoff bekommen? Während die genaue Reihenfolge der Impfstoffempfänger von Staat zu Staat unterschiedlich sein kann, werden die meisten Ärzte und Bewohner von Langzeitpflegeeinrichtungen an erster Stelle stehen. Wenn Sie verstehen möchten, wie diese Entscheidung getroffen wird, hilft dieser Artikel.
    • Wann kann ich nach der Impfung wieder zum normalen Leben zurückkehren? Das Leben wird erst wieder normal, wenn die Gesellschaft als Ganzes ausreichend Schutz gegen das Coronavirus erhält. Sobald die Länder einen Impfstoff zugelassen haben, können sie in den ersten Monaten höchstens einige Prozent ihrer Bürger impfen. Die nicht geimpfte Mehrheit bleibt weiterhin anfällig für Infektionen. Eine wachsende Anzahl von Coronavirus-Impfstoffen zeigt einen robusten Schutz vor Krankheit. Es ist aber auch möglich, dass Menschen das Virus verbreiten, ohne zu wissen, dass sie infiziert sind, weil sie nur leichte oder gar keine Symptome haben. Wissenschaftler wissen noch nicht, ob die Impfstoffe auch die Übertragung des Coronavirus blockieren. Selbst geimpfte Menschen müssen vorerst Masken tragen, Menschenmassen in Innenräumen meiden und so weiter. Sobald genügend Menschen geimpft sind, wird es für das Coronavirus sehr schwierig, gefährdete Personen zu finden, die infiziert werden können. Je nachdem, wie schnell wir als Gesellschaft dieses Ziel erreichen, könnte sich das Leben im Herbst 2021 einem normalen Zustand nähern.
    • Muss ich nach der Impfung noch eine Maske tragen? Ja, aber nicht für immer. Hier ist der Grund. Die Coronavirus-Impfstoffe werden tief in die Muskeln injiziert und stimulieren das Immunsystem zur Produktion von Antikörpern. Dies scheint ein ausreichender Schutz zu sein, um die geimpfte Person vor einer Krankheit zu bewahren. Was jedoch nicht klar ist, ist, ob es möglich ist, dass das Virus in der Nase blüht – und geniest oder ausgeatmet wird, um andere zu infizieren -, selbst wenn Antikörper an anderer Stelle im Körper mobilisiert wurden, um zu verhindern, dass die geimpfte Person krank wird. Die klinischen Impfstoffstudien sollten feststellen, ob geimpfte Menschen vor Krankheiten geschützt sind – und nicht herausfinden, ob sie das Coronavirus noch verbreiten können. Basierend auf Studien zu Grippeimpfstoffen und sogar mit Covid-19 infizierten Patienten haben Forscher Grund zu der Hoffnung, dass geimpfte Menschen das Virus nicht verbreiten, aber weitere Forschung ist erforderlich. In der Zwischenzeit müssen sich alle – auch geimpfte Menschen – als mögliche stille Streuer vorstellen und weiterhin eine Maske tragen. Lesen Sie hier mehr.
    • Wird es wehtun? Was sind die Nebenwirkungen? Der Impfstoff gegen Pfizer und BioNTech wird wie andere typische Impfstoffe als Schuss in den Arm abgegeben. Die Injektion in Ihren Arm fühlt sich nicht anders an als bei jedem anderen Impfstoff, aber die Rate kurzlebiger Nebenwirkungen scheint höher zu sein als bei einer Grippeschutzimpfung. Zehntausende Menschen haben die Impfstoffe bereits erhalten, und keiner von ihnen hat ernsthafte gesundheitliche Probleme gemeldet. Die Nebenwirkungen, die den Symptomen von Covid-19 ähneln können, dauern etwa einen Tag und treten nach der zweiten Dosis wahrscheinlicher auf. Frühe Berichte aus Impfstoffversuchen deuten darauf hin, dass einige Menschen möglicherweise einen Tag frei nehmen müssen, weil sie sich nach Erhalt der zweiten Dosis mies fühlen. In der Pfizer-Studie entwickelte etwa die Hälfte Müdigkeit. Andere Nebenwirkungen traten bei mindestens 25 bis 33 Prozent der Patienten auf, manchmal mehr, einschließlich Kopfschmerzen, Schüttelfrost und Muskelschmerzen. Obwohl diese Erfahrungen nicht angenehm sind, sind sie ein gutes Zeichen dafür, dass Ihr eigenes Immunsystem eine starke Reaktion auf den Impfstoff zeigt, die eine dauerhafte Immunität bietet.
    • Werden mRNA-Impfstoffe meine Gene verändern? Nein. Die Impfstoffe von Moderna und Pfizer verwenden ein genetisches Molekül, um das Immunsystem zu stärken. Dieses als mRNA bekannte Molekül wird schließlich vom Körper zerstört. Die mRNA ist in einer öligen Blase verpackt, die mit einer Zelle verschmelzen kann, so dass das Molekül hineinrutschen kann. Die Zelle verwendet die mRNA, um Proteine ​​aus dem Coronavirus herzustellen, die das Immunsystem stimulieren können. Zu jedem Zeitpunkt kann jede unserer Zellen Hunderttausende von mRNA-Molekülen enthalten, die sie produzieren, um eigene Proteine ​​herzustellen. Sobald diese Proteine ​​hergestellt sind, zerkleinern unsere Zellen die mRNA mit speziellen Enzymen. Die mRNA-Moleküle, die unsere Zellen herstellen, können nur wenige Minuten überleben. Die mRNA in Impfstoffen ist so konstruiert, dass sie den Enzymen der Zelle etwas länger standhält, sodass die Zellen zusätzliche Virusproteine ​​bilden und eine stärkere Immunantwort auslösen können. Die mRNA kann jedoch höchstens einige Tage halten, bevor sie zerstört wird.

Deutschland plant, am 27. Dezember mit der Immunisierung von Menschen über 80 Jahren und anderen Personen zu beginnen, die in Pflegeheimen leben, ein oder zwei Tage nach den voraussichtlich 400.000 Dosen, die es bestellt hat. Es ist geplant, die ersten Impfungen von Ärzteteams durchzuführen, die Pflegeheime besuchen. In den ersten Januarwochen werden Hunderte von Impfzentren in Hallen, Turnhallen und Theatern eröffnet.

Für viele Deutsche war es schwierig zu sehen, dass ein von ihren eigenen Bürgern entwickelter Impfstoff die Zulassung erhält und Wochen vor seiner geplanten Ankunft in ihrem eigenen Land in Großbritannien verabreicht wird.

Doch der Gesundheitsminister des Landes, Jens Spahn, hat sich gegen die Kritik gewehrt.

“Es gibt dem Vertrauen und der Verantwortung in ganz Europa viel Glauben, dass wir dies gemeinsam tun”, sagte Spahn letzte Woche gegenüber Reportern. “‘Wir’ sind stärker als ‘Ich'”, sagte er.

Frankreich, die zweitgrößte Volkswirtschaft der Region, wird Ende des Monats ebenfalls mit den Aufnahmen beginnen. Die Behörden dort stehen jedoch vor einer zusätzlichen Herausforderung: der Impfskepsis. Eine kürzlich durchgeführte Umfrage ergab, dass nur 41 Prozent der Befragten die Injektionen planen.

Italien und Spanien, zwei der am stärksten betroffenen europäischen Länder, bewegen sich ebenfalls schnell. Bis Ende dieses Monats finden zumindest einige Impfungen gegen die am stärksten gefährdeten Personen statt. Der Großteil wird im Januar beginnen.

Es ist den Gesundheitsbeamten in ganz Europa nicht entgangen, dass die ersten Impfungen einen übergroßen symbolischen Wert in der Kampagne gegen müde und manchmal skeptische Bevölkerungsgruppen haben könnten.

In Griechenland wurde die Impfaktion von einer Regierung, die darauf aus ist, widerstrebende Bürger für sich zu gewinnen, als Operation Freedom bezeichnet. Eine kürzlich dort durchgeführte Meinungsumfrage ergab, dass drei von zehn Griechen nicht beabsichtigten, sich impfen zu lassen, und Bedenken hinsichtlich Wirksamkeit und Sicherheit äußerten. Weitere drei von zehn Befragten äußerten sich skeptisch.

In Italien sagte Alessio D’Amato, der oberste Gesundheitsbeamte in der Region Latium, zu der auch Rom gehört, der italienischen Zeitung Corriere della Sera, dass die erste Person, die dort geimpft wird, „eine Krankenschwester und eine Frau sein wird – genau wie in New York. “

Bisher hat kein EU-Land Pläne angekündigt, den Impfstoff verbindlich zu machen.

Und obwohl der Druck besteht, die meisten Menschen in kürzester Zeit zu impfen, warnen Experten, dass die Behörden nicht zu schnell vorgehen sollten, insbesondere wenn sie nicht zuversichtlich in die Infrastruktur ihres Landes sind.

“Der beste Ansatz, insbesondere wenn Bedenken hinsichtlich der Logistik bestehen, besteht darin, langsam und stetig vorzugehen”, sagte Prof. Jean-Michel Dogné von der Universität Namur, Belgien, ein Berater der Europäischen Arzneimittel-Agentur.

“Nichts Schlimmeres kann passieren, als jemanden mit einem Impfstoff zu impfen, für den wir die Qualität nicht garantieren können”, sagte er.

Laut Professor Dogné besteht die größte Herausforderung für jedes Land darin, die Temperatur des Pfizer-BioNTech-Impfstoffs auf seinem Weg von der Fabrik bis zur Injektion zu verfolgen.

Die Impfkampagne wird im ersten Quartal 2021 in der Europäischen Union ernsthaft in Gang kommen, und die meisten Regierungen hoffen, dass bis Juni große Teile ihrer Bevölkerung geimpft werden.

Pfizer und die Europäische Kommission geben an, an einem spezifischen Zeitplan für künftige Impfstofflieferungen zu arbeiten, haben jedoch keine Einzelheiten mitgeteilt. Die Steigerung der Produktion ist eine Herausforderung für das Unternehmen, das mehrere Kunden bedient, und die europäischen Regierungen haben Bedenken geäußert, dass das Angebot zu einem Rinnsal werden könnte.

Professor Dogné sagte, dies sei umso mehr ein Grund, es richtig zu machen und sicherzustellen, dass keine der kostbaren Dosen verschwendet werde.

“Dies ist eine beispiellose Operation”, sagte er. “Wir dürfen keinen Tropfen verschwenden.”

Die Berichterstattung wurde von Melissa Eddy aus Berlin beigesteuert; Aurelien Breeden aus Paris; Emma Bubola aus Rom; Monika Pronczuk aus Warschau; Niki Kitsantonis aus Athen; und Raphael Minder aus Madrid.