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Health

Kids’s Display Time Has Soared within the Pandemic, Alarming Mother and father and Researchers

Overall, children’s screen time had doubled year over year by May, according to Qustodio, a company that tracks usage on tens of thousands of devices used by children ages 4-15 worldwide. The data showed that usage increased over time: in the US, for example, children spent an average of 97 minutes a day on YouTube in March and April, compared with 57 minutes in February, and almost twice as much as a year earlier – with similar ones Trends in the UK and Spain. The company calls the monthly increase “The Covid Effect”.

Children turn to screens because they say they have no alternative activities or entertainment options – this is where they meet up with friends and go to school – while technology platforms take advantage of it by gaining loyalty through tactics like virtual money rewards or perks in “Limited Edition” seduce you for maintaining the daily “streak” of use.

“This was a gift for them – we gave them a captive audience: our children,” said Dr. Dimitri Christakis, director of the Center for Child Health, Behavior, and Development at Seattle Children’s Research Institute. The costs are borne by the families, said Dr. Christakis, since increased online use is linked to anxiety, depression, obesity and aggression – “and the dependence on the medium itself”.

Crucially, the research only shows associations, which means heavy internet use doesn’t necessarily cause these problems. What concerns the researchers, at least, is that the use of devices is a poor substitute for activities known to be central to health, social, and physical development, including physical games and other interactions with which Children learn to deal with challenging social situations.

Yet parents express a kind of hopelessness with their options. Adhering to the pre-pandemic rules doesn’t just seem impractical, it can feel downright mean to keep children away from an important source of socializing.

Updated

Jan. 15, 2021, 8:45 p.m. ET

“So I take it away and you do what? A puzzle? Learn to sew? Knit? I don’t know what the expectations are, ”said Paraskevi Briasouli, a corporate writer who is raising four children, ages 8, 6, 3, and 1 in a two-bedroom Manhattan apartment with her husband. Device time has replaced sport on weekday afternoons and is up 70 percent on weekends, she said.

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Business

Aid Therapeutics shares have soared 38,000% in 2020

Medical staff examine a patient in the Covid-19 intensive care unit at the United Memorial Medical Center in Houston on November 16, 2020.

Go Nakamura | Getty Images

LONDON – Swiss biotech company Relief Therapeutics saw its share price jump 38,000% this year as it develops a drug that focuses on respiratory failure due to severe Covid-19.

Last week, the company, together with US partner NeuroRx, achieved the target agreed with the US Food and Drug Administration of 165 patients in the ongoing Phase 2b / 3 study with RLF-100, a patented version of Aviptadil.

Aviptadil is a synthetic formulation of a naturally occurring peptide called Vasoactive Intestinal Polypeptide (VIP), which is primarily concentrated in the lungs and resets the immune system’s response, acts as a vasodilator, and promotes the production of surfactant in the lungs allowing the transfer of blood oxygen.

RLF-100 has been around since 2000, when it was developed to treat acute respiratory distress and other lung diseases and was subsequently acquired by Biogen. Earlier this year, Relief scientists discovered that it could protect the cell attacked by the Covid-19 virus.

Ram Selvaraju, chairman of Relief Therapeutics, spoke to CNBC from New York by phone that the ongoing study is expected to provide topline data in the first half of January, and attributed the company’s stock price surge in part to evidence of effectiveness in ” otherwise untreatable patients. “

“Where other people have mainly focused on lightly infected or moderately infected people, we have tried carefully to see if our drug can benefit the seriously ill and the terminally ill,” he said.

Early results of extended access use of RLF-100 in patients with critical Covid-19 and severe comorbidities showed that 72% of patients admitted to the ICU survived.

Relief Therapeutics had a market cap of less than 100 million Swiss Francs ($ 113 million) in late July and surpassed the first 21 patients treated with RLF-100 under the FDA Expanded Access Protocol on August 10 after promising results 1.6 billion Swiss people. Since then, it has flattened to just under CHF 1 billion.

The 38,000% increase largely corresponds to the low level of the original share price, which was just under 0.40 Swiss francs per share on Friday afternoon. Shares in the multinational Roche, on the other hand, are worth 306 francs.

Other therapeutics that have been tested on patients with more moderate symptoms have been purchased by government agencies to help fight the pandemic. The US government’s Operation Warp Speed ​​ordered Gileads Remdesivir and Eli Lillys Bamlanivimab.

Selvaraju announced that Relief Therapeutics and NeuroRx were in contact with Operation Warp Speed, and said that if the drug successfully proves its effectiveness in critically ill patients after phase three randomized tests, the company expects to see stock orders on a scale similar to that Gilead and Eli Lilly. A US Department of Health spokesman was not immediately available for comment when contacted CNBC.

Covid the “tip of the iceberg”

In June, the FDA granted RLF-100 fast-track designation and also received orphan drug designation for the treatment of acute respiratory distress syndrome (ARDS).

Since the drug is not an antiviral drug specifically designed to fight the coronavirus, Relief Therapeutics hopes the current pandemic is “a chance for this drug to shine” if it turns out to be a therapeutic one clinical benefit in the treatment of respiratory disease due to Covid- hat. 19th

“Covid-19 is really the tip of the iceberg, the head of the spear. If we can prove this drug works for Covid-19-related respiratory distress, we will assume that we can use these results to further develop the drug testing.” in other forms of acute respiratory distress syndrome unrelated to Covid-19, “Selvaraju said, adding that this puts Relief Therapeutics in a” pretty unique position “.

“While many other experimental therapeutics will either live or die due to the development of the pandemic, on the contrary, we believe that once we have established the therapeutic benefits of this drug in the context of Covid-19, hopefully we should have our long-term vision for this drug too a kind of workhorse for emergency rooms and intensive care units as well as hospitals and hospital systems everywhere. “