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Health

Biden Picks Biotech Government to Lead New Biomedical Analysis Company

WASHINGTON — President Biden, who outlined a vision for “bold approaches” to fighting cancer and other diseases, announced Monday that he was recruiting Dr. Renee Wegrzyn, a Boston-based biotech executive with government experience, was selected to serve as director of a new federal agency in pursuit of risky, far-reaching ideas that drive biomedical innovation.

Mr. Biden made the announcement at the John F. Kennedy Presidential Library and Museum in Boston on the 60th anniversary of the former president’s “moonshot” speech, which ushered in an era of space travel. He took the opportunity to reiterate his call to “End Cancer As We Know It” – the slogan for his own “Cancer Moonshot” initiative.

“Imagine the possibilities — vaccines that could prevent cancer, as HPV does,” the president said, referring to the human papillomavirus, which can cause cervical cancer. “Imagine molecular zip codes that could precisely deliver drugs and gene therapies to the right tissues. Imagine simple blood tests during an annual checkup that could detect cancer early.”

Mr. Biden, whose son Beau died of brain cancer in 2015, has a deep personal commitment to advancing cancer research, and the Kennedy Library was a reminder of that. Another Kennedy, former Senator Edward M. Kennedy, whom Mr. Biden described as “one of my dearest friends,” died in 2009 from the same type of cancer — glioblastoma — as Beau Biden.

Mr. Biden helped create the Cancer Moonshot when he was Vice President. His goal, which he described as “quite feasible,” is to reduce cancer death rates by at least 50 percent over the next 25 years while “converting death sentences into chronic diseases.”

With the midterm elections approaching, here stands President Biden.

He proposed the new biomedical research agency earlier this year as part of efforts to revitalize the initiative.

Modeled on the Defense Advanced Research Projects Agency, the new agency is known as the Advanced Research Projects Agency for Health. (In Washington argot, where each agency has an acronym, the Defense Research Agency is called DARPA and the Health Agency is ARPA-H.)

The agency aims to be nimble and flexible — a kind of “shark tank” for biomedical research, populated by “brilliant visionary talents” who will invest in untested approaches, knowing that “a significant proportion of projects are likely to fail,” said Dr . Francis Collins, the former director of the National Institutes of Health who now serves as Mr Biden’s acting scientific adviser and helped find the new director.

dr Wegrzyn is vice president of business development at Ginkgo Bioworks and leads innovation at Concentric by Ginkgo, the company’s initiative to promote coronavirus testing and track the spread of the virus. She also worked at DARPA and its sister agency, the Intelligence Advanced Research Projects Activity.

“Some of the problems we face every day — particularly when it comes to health and disease — are so vast that they can seem insurmountable,” said Dr. Wegrzyn in a White House statement. “I’ve seen firsthand the tremendous expertise and energy the US biomedical and biotechnology company can bring to solve some of the toughest challenges in healthcare.”

Congress has approved $1 billion for ARPA-H, which is housed at the National Institutes of Health but reports directly to Xavier Becerra, Secretary of Health and Human Services – an agreement intended to prevent the new agency too busy with the federal bureaucracy. While its director is not a Senate-approved position, Mr. Biden could be pushed back by Republicans, some of whom have argued that the agency is duplicating the NIH’s efforts.

The agency already has an acting associate director, Adam H. Russell, also a DARPA alumnus, who provided the technical infrastructure and other foundations to get the new agency off the ground. dr Collins said Dr. Wegrzyn will start work on October 1st. Her primary goal will be to hire program managers who will bring bold ideas that the agency wants to pursue, and will spend a limited time, perhaps three years, with the agency, he said.

“They’ll arrive, they’ll do a little due diligence, and then they’ll have to get the idea of ​​Dr. suggest Wegrzyn,” said Dr. Collins. “If she says ‘thumbs up,’ they’ll go off with whatever money they can spend to figure out how to put together the right partners to get the job done.”

The emergence of successful new innovations, he said, will take time. But Steve Brozak, an investment banker whose firm WBB Securities specializes in biotechnology, said if the agency is to be a success, Dr. Wegrzyn acted quickly to differentiate their work from the rest of the federal bureaucracy.

“What she needs to do is get a win on the board right away,” he said. “It doesn’t mean money. This means something that can be seen outside of the current paradigm in promoting health care for all.”

Mr. Biden’s selection was commended by Ellen V. Sigal, chair of Friends of Cancer Research, a nonprofit organization that works with industry and government to advance new therapies. Mrs. Sigal called Dr. Wegrzyn “an inspired choice,” adding that “she is a proven innovator and leader who knows science, knows how to make governments work and understands the urgency for patients across the country.”

In addition to announcing his intention to have Dr. Wegrzyn, Mr. Biden on Monday issued an executive order establishing a biotechnology and biomanufacturing initiative that aims to position the United States as a leader in the field and center drug manufacturing in the country. The coronavirus pandemic has exposed critical vulnerabilities in the supply chain for medicines and life-saving therapies.

“The United States has relied heavily on foreign materials for biomanufacturing for too long,” the White House said in a statement, “and our past outsourcing of critical industries, including biotechnology, poses a threat to our ability to access key materials such as including the active pharmaceutical ingredients for life-saving medicines.”

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World News

Ford poaches high tech govt Doug Subject who helped lead Apple’s top-secret automobile mission

Ford Motor Co. displays a new 2021 Ford F-150 pickup truck at the Rouge Complex in Dearborn, Michigan, September 17, 2020.

Rebecca Cook | Reuters

DETROIT – Ford Motor has hired former Tesla and Apple executive Doug Field to lead its emerging technology efforts, a key focus for the automaker under its new Ford+ turnaround plan.

Field, who led development of Tesla’s Model 3, most recently served as vice president of special projects at Apple, which reportedly included the tech giant’s Titan car project.

The hire is a major new addition for Ford, while a big hit to Apple and its secret car project, which the company has yet to confirm exists.

“I think any time you lose a well-respected, experienced executive who, as best we can tell, was really directing the automotive efforts at Apple, it’s a blow to any company,” Bernstein analyst Toni Sacconaghi, who covers the iPhone maker, said Tuesday on CNBC’s “Closing Bell.” 

Ford on Tuesday said Field will serve in the new position of chief advanced technology and embedded systems officer. He will lead Ford’s vehicle controls, enterprise connectivity, features, integration and validation, architecture and platform, driver assistance technology and digital engineering tools.

“His talent and commitment to innovation that improves customers’ lives will be invaluable as we build out our Ford+ plan to deliver awesome products, always-on customer relationships and ever-improving user experiences,” Ford CEO Jim Farley said in a statement. “We are thrilled Doug chose to join Ford and help write the next amazing chapter of this great company.” 

Field, who will report to Farley, actually began his professional career at Ford in 1987, according to his LinkedIn profile. He then held positions at Johnson & Johnson, Deka Research & Development and Segway before starting at Apple in 2008. After more than five years with the tech giant, he moved to Tesla before returning to Apple in 2018.

– CNBC’s Kevin Stankiewicz contributed to this report

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Politics

Trump shouldn’t lead GOP ticket in 2024, retiring Sen. Pat Toomey says

Senator Pat Toomey will speak to CNBC at the Ambrosetti Forum in Italy on September 3, 2021.

Mike Green | CNBC

Senator Pat Toomey has urged his party not to nominate former President Donald Trump as a presidential candidate in 2024 and described his behavior after the 2020 elections as “totally unacceptable”.

The Pennsylvania Republican voted to have Trump impeached for his role in fueling his supporters’ Sept. 6 attack on the Capitol.

Speaking to CNBC at the Ambrosetti Forum in Italy on Friday, Toomey, who does not intend to seek re-election in 2022, suggested his party consider other presidential candidates in 2024.

“I think the future of our party is to be a party of ideas, not a party about a single person, and I think we will learn a lot from the next primaries,” he said.

“I think after what happened after the 2020 elections, I think the president’s behavior was completely unacceptable, so I don’t think he should be the candidate for the party leadership in 2024.”

Despite his staunch conservative track record of a two-decade long Congress career, Toomey has broken away from the unwavering allegiance to the former president that now serves as the litmus test in the GOP. The Pennsylvania Republican Party narrowly voted against formally reprimanding Toomey for his vote in condemnation of Trump in March, issuing a “strong reprimand” instead.

“I’m a Conservative Republican in every objective way when I look at the election results by comparing my views with those of a traditional Conservative Republican,” Toomey told CNBC Steve Sedgwick.

“It is President Trump who has deviated from Republican and Conservative orthodoxy in various ways. I stuck to the conservative views I’ve had for a long time, he had a different view on issues like trade and sometimes immigration.” And other things.”

Trump’s loyalty and a dispute over the investigation into the deadly storming of the Capitol have become focal points in a battle for the soul of the Republican Party in recent months.

The right-wing House Freedom Caucus has launched a print campaign urging House Minority Leader Kevin McCarthy to expel Reps Liz Cheney and Adam Kinzinger from the Republican conference for agreeing to stand on the Capitol Special Committee on Dec. January to work with.

The former president still has significant power over the GOP, with loyal candidates aiming to oust incumbent and established Republicans in regional primaries across the country, while Trump continues to spread lies about the theft of the 2020 elections.

Toomey also criticized Trump’s agreement with the Taliban to completely withdraw US forces from Afghanistan.

“I think we were at a point and we could have maintained a very modest presence on the ground, an extremely low casualty rate, and we had not had a death in Afghanistan for well over a year, and at a modest financial cost . ” ,” he said.

“For this price we would have supported the Afghans, who were actually the spearheads who fight, and could have prevented the reappearance of terrorists from a state controlled by the Taliban.”

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Health

Covid delta will result in improve in breakthrough infections: Moderna

The highly contagious Delta variant will lead to an increase in breakthrough infections in those who are fully vaccinated as people begin to exercise indoors after the summer, Moderna said Thursday.

While Moderna’s two-dose vaccine remains “stable” six months after the second vaccination, immunity to the coronavirus will continue to decline and ultimately reduce the vaccine’s effectiveness, the company said in the slides accompanying its second quarter earnings report were attached.

The company said its vaccine was 93% effective six months after the second dose. By comparison, Pfizer and BioNTech reported that their vaccine effectiveness decreased to about 84% after six months.

“Given this overlap, we believe a dose 3 refresh will likely be needed before the winter season,” wrote Moderna.

Moderna’s warning comes as the Delta variant becomes more widespread in more than 100 countries, including the United States. Delta, the predominant form of the disease in the United States, is more transmissible than the common cold, 1918 Spanish flu, smallpox, Ebola, MERS, and SARS, according to the Centers for Disease Control and Prevention.

A healthcare worker treats a patient in a negative pressure room in the Covid-19 Intensive Care Unit (ICU) at Freeman Hospital West in Joplin, Missouri, Tuesday, August 3, 2021.

Angus seed dressings | Bloomberg | Getty Images

For some Americans, concerns about the effectiveness of the vaccine have grown with the advent of the variant, which can cause more serious illnesses than the original coronavirus. Some people have even gone so far as to look for an extra dose not yet recommended by the CDC. This week, San Francisco health officials announced that they would allow patients who received the Johnson & Johnson vaccine to have a second vaccination from Pfizer-BioNTech or Moderna.

Drug makers have been saying for months that they expect people to need booster shots and perhaps additional doses annually at some point, just like they did with seasonal flu.

Moderna said Thursday that results from a Phase 2 study showed that a booster dose of its vaccine elicited a “robust” antibody response against three variants, including Delta.

The CDC and World Health Organization say booster doses are not currently required due to a lack of data. In fact, on Wednesday the WHO called on wealthy nations to stop distributing Covid booster vaccinations to give the world a chance to meet the WHO’s goal of vaccinating 10% of each country’s population by October.

“We need an urgent turnaround from moving the majority of vaccines to high-income countries and the majority to low-income countries,” said WHO Director-General Tedros Adhanom Ghebreyesus.

The move comes after Israel announced that the country will be giving booster doses to its elderly population. The Dominican Republic has also given its population booster doses, while neighboring Haiti recently secured its first vaccine doses.

People in the US are also finding ways to get booster vaccinations.

– CNBC’s Rich Mendez contributed to this report.

Categories
Entertainment

As New York Reopens, It Appears for Tradition to Lead the Approach

Broadway is planning to start performances of at least three dozen shows before the end of the year, but producers do not know if there will be enough tourists — who typically make up two-thirds of the audience — to support all of them.

The Metropolitan Opera is planning a September return, but only if its musicians agree to pay cuts.

And New York’s vaunted nightlife scene — the dance clubs and live venues that give the city its reputation for never sleeping — has been stymied by the slow, glitchy rollout of a federal aid program that mistakenly declared some of the city’s best-known nightclub impresarios to be dead.

The return of arts and entertainment is crucial to New York’s economy, and not just because it is a major industry that employed some 93,500 people before the pandemic and paid them $7.4 billion in wages, according to the state comptroller’s office. Culture is also part of the lifeblood of New York — a magnet for visitors and residents alike that will play a key role if the city is to remain vital in an era when shops are battling e-commerce, the ease of remote work has businesses rethinking the need to stay in central business districts and the exurbs are booming.

“What is a city without social, cultural and creative synergies?” Gov. Andrew M. Cuomo asked earlier this year in an address on the importance of the arts to the city’s recovery. “New York City is not New York without Broadway. And with Zoom, many people have learned they can do business from anywhere. Compound this situation with growing crime and homelessness and we have a national urban crisis.”

And Mayor Bill de Blasio — who could seem indifferent to the arts earlier in his tenure — has become a cultural cheerleader in the waning days of his administration, starting a $25 million program to put artists back to work, creating a Broadway vaccination site for theater industry workers and planning a “homecoming concert” in Central Park next month featuring Bruce Springsteen, Jennifer Hudson and Paul Simon to herald the city’s return.

Eli Dvorkin, editorial and policy director at the Center for an Urban Future, said, “The way I look at it, there is not going to be a strong recovery for New York City without the performing arts’ leading the way.” He added, “People gravitate here because of the city’s cultural life.”

There are signs of hope everywhere, as vaccinated New Yorkers re-emerge this summer. Destinations like the Whitney and the Brooklyn Museum are crowded again, although timed reservations are still required. Bruce Springsteen is playing to sold-out crowds on Broadway and Foo Fighters brought rock back to Madison Square Garden.

Shakespeare in the Park and the Classical Theater of Harlem are staging contemporary adaptations of classic plays in city parks; the Park Avenue Armory, the Brooklyn Academy of Music, and a number of commercial Off Broadway theaters have been presenting productions indoors; and a new outdoor amphitheater is drawing crowds for shows on Little Island, the new Hudson River venue.

Haley Gibbs, 25, an administrative aide who lives in Brooklyn, said she felt the city’s pulse returning as she waited to attend “Drunk Shakespeare,” an Off Off Broadway fixture that has resumed performances in Midtown.

“I feel like it’s our soul that’s been given back to us, in a way,” Gibbs said, “which is super dramatic, but it is kind of like that.”

But some of the greatest tests for the city’s cultural scene lie ahead.

Hunkering down — cutting staff, slashing programming — turned out to be a brutal but effective survival strategy. Arts workers faced record unemployment, and some have yet to return to work, but many businesses and organizations were able to slash expenses and wait until it was safe to reopen. Now that it’s time to start hiring and spending again, many cultural leaders are worried: Can they thrive with fewer tourists and commuters? How much will safety protocols cost? Will the donors who stepped up during the emergency stick around for a less glamorous period of rebuilding?

“Next year may prove to be our most financially challenging,” said Bernie Telsey, one of the three artistic directors at MCC Theater, an Off Broadway nonprofit. “In many ways, it’s like a start-up now — it’s not just turning the lights on. Everything is a little uncertain. It’s like starting all over again.”

The fall season is shaping up to be the big test. “Springsteen on Broadway” began last month, but the rest of Broadway has yet to resume: The first post-shutdown play, a drama about two existentially trapped Black men called “Pass Over,” is to start performances Aug. 4, while the first musicals are aiming for September, starting with “Hadestown” and “Waitress,” followed by war horses that include “The Lion King,” “Chicago,” “Wicked” and “Hamilton.”

The looming question is whether there will be enough theatergoers to support all those shows. Although there have been signs that some visitors are returning to the city, tourism is not expected to rebound to its prepandemic levels for four years. So some of the returning Broadway shows will initially start with reduced schedules — performing fewer than the customary eight shows a week — as producers gauge ticket demand.

And “Harry Potter and the Cursed Child,” a big-budget, Tony-winning play that was staged in two parts before the pandemic, will be cut down to a single show when it returns to Broadway on Nov. 12; its producers cited “the commercial challenges faced by the theater and tourism industries emerging from the global shutdowns.”

“What we need to do, which has never been done before, is open all of Broadway over a single season,” said Tali Pelman, the lead producer of “Tina — The Tina Turner Musical.”

A City Stirs

As N.Y.C. begins its post-pandemic life, we explore Covid’s long-lasting impact on the city.

Safety protocols have been changing rapidly, as more people get vaccinated, but there is still apprehension about moving too fast. In Australia, reopened shows have periodically been halted by lockdowns, while in England, several shows have been forced to cancel performances to comply with isolation protocols that some view as overly restrictive.

“On a fundamental level, our health is at stake,” said Lin-Manuel Miranda, the creator of “Hamilton,” which is planning to resume performances on Broadway on Sept. 14. “You get this wrong, and we open too soon, and then we re-spike and we close again — that’s almost unthinkable.”

Some presenters worry that, with fewer tourists, arts organizations will be battling one another to win the attention of New Yorkers and people from the region.

“There’s going to be a lot of competition for a smaller audience at the beginning, and that’s scary,” said Todd Haimes, artistic director of the Roundabout Theater Company, a nonprofit that operates three theaters on Broadway and two Off Broadway.

Another looming challenge: concerns about public safety. Bystanders were struck by stray bullets during shooting incidents in Times Square in May and June, prompting Mayor de Blasio to promise additional officers to protect and reassure the public in that tourist-and-theater-dense neighborhood.

The city’s tourism organization, NYC & Company, has developed a $30 million marketing campaign to draw visitors back to the city. The Broadway League, a trade organization representing producers and theater owners, is planning its own campaign. The Tony Awards are planning a fall special on CBS that will focus on performances in an effort to boost ticket sales. And comeback come-ons are finding their way into advertising: “We’ve been waiting for you,” “Wicked” declares in a direct mail piece.

The economic stakes for the city are high. Broadway shows give work to actors and singers and dancers and ushers, but also, indirectly, to waiters and bartenders and hotel clerks and taxi drivers, who then go on to spend a portion of their paychecks on goods and services. The Broadway League says that during the 2018-2019 season Broadway generated $14.7 billion in economic activity and supported 96,900 jobs, when factoring in the direct and indirect spending of tourists who cited Broadway as a major reason for visiting the city.

“We’ve pushed through a really tough time, and now you have this new variant, which is kind of scary, but I still hope we’re on the right track,” said Shane Hathaway, the co-owner of Hold Fast, a Restaurant Row bar and eatery whose website asks “Do you miss the Performing Arts?? So do we!!” “We’re already seeing a lot more tourists than last year,” Hathaway said, “and my hope is that we continue.”

At the tourist-dependent Met Museum, attendance is back, but not all the way: it’s now open five days a week, and has drawn 10,000 people many days, while before the pandemic it was open seven days a week and averaged 14,000 daily visitors. Plus: more of the visitors now are local, and they don’t have to pay admission; the Met continues to project a $150 million revenue loss due to the pandemic.

If the Met, the largest museum in the country, is struggling, that means smaller arts institutions are hurting even more, particularly those outside Manhattan, which tend to have less foot traffic and fewer big donors. The Brooklyn Academy of Music, for example, is trying to recover from a pandemic period without when it lost millions in revenue, reduced staff and had to raid its endowment to pay the bills.

The city’s music scene has faced its own challenges — from the diviest bars to nightclubs to the plush Metropolitan Opera.

According to a study commissioned by the mayor’s office, some 2,400 concert and entertainment venues in New York City supported nearly 20,000 jobs in 2016. But the sector has had a hard time.

Many are waiting to see if they will get help from a $16 billion federal grant fund intended to preserve music clubs, theaters and other live-event businesses devastated by the pandemic. But the rollout of the program, the Shuttered Venue Operators Grant initiative, has been slow and bumpy. Some owners, including Michael Swier, the founder of the Bowery Ballroom and the Mercury Lounge in New York, were initially denied aid because the program mistakenly believed they were dead.

Elsewhere, a music and arts space with a 1,600-person capacity in the heart of hipster Brooklyn, cut its staff from 120 people to 5 when the pandemic arrived. After the state lifted restrictions on smaller venues in June, it reopened and began hiring back some workers, but its owners fear it could take a year or two to return to profitability.

The club got help in the form of a $4.9 million shuttered venue grant from the federal government, which it said would be used to pay its debts — including for rent, utilities, and loans — and to fix up the space and pay staff. “Every dollar will be used just to dig ourselves out from Covid,” said one of the venue’s partners, Dhruv Chopra.

And the Met Opera is still not sure if it can raise its gilded curtain in September, as planned, after the longest shutdown in its history. The company, which lost $150 million in earned revenues during the pandemic, recently struck deals to cut the pay of its choristers, soloists and stagehands. The company is now in tense negotiations with the musicians in its orchestra, who were furloughed without pay for nearly a year. If they fail to reach a deal, the Met, the largest performing arts organization in the nation, risks missing being part of the initial burst of reopening energy.

Some cultural leaders are already looking past the fall, at the challenge of sustaining demand for tickets after the initial enthusiasm of reopening fades.

“We have a lot of work to do to make sure that people know that we’re open,” said Thomas Schumacher, president of Disney Theatrical Productions, “to make people comfortable coming in, to keep the shows solid, and to get through the holidays and get through the winter.”

Laura Zornosa contributed reporting.

Categories
Health

Asia Struggles to Forged Off the Pandemic Regardless of its Early Lead

SYDNEY, Australia – Across the Asia-Pacific region, the countries that led the world in containing the coronavirus are now languishing in the race to leave it behind.

As the US, which has suffered far worse outbreaks, now crampers stadiums with vaccinated fans and planes with summer vacationers, the pandemic champions of the east are still caught in a cycle of uncertainty, restriction and isolation.

In southern China, the spread of the Delta variant led to a sudden lockdown in Guangzhou, a major industrial capital. Taiwan, Vietnam, Thailand and Australia have also cracked down on the recent outbreaks, while Japan is grappling with its own fatigue from a fourth round of infections riddled with fears of a virus disaster from the Olympics.

Wherever they can, people move on with their lives, with masks and social distancing and outings near their home. Economically, the region weathered the pandemic relatively well, as most countries successfully mastered their first phase.

But with hundreds of millions of people from China to New Zealand still unvaccinated – and with concerned leaders keeping international borders closed for the foreseeable future – tolerance for restricted lives is getting thinner, even though the new varieties add to the threat.

Put simply, people are fed up with asking themselves: Why are we behind us and when will the pandemic routine for the love of the good finally come to an end?

“When we’re not stuck, it’s like we’re waiting in the glue or mud,” said Terry Nolan, director of the vaccines and immunization research group at the Doherty Institute in Melbourne, Australia, a city of five million people barely out of his last lockdown. “Everyone is trying to get out to find a sense of urgency.”

While languishing varies from country to country, it is generally due to a lack of vaccines.

In some places, such as Vietnam, Taiwan and Thailand, there are hardly any vaccination campaigns. Others, like China, Japan, South Korea, and Australia, have seen a sharp surge in vaccinations in recent weeks, but are far from offering vaccines to anyone who wants one.

But almost everywhere in the region, the trend lines point to a trend reversal. While Americans celebrate what feels like a new dawn for many of the 4.6 billion people in Asia, the rest of this year will be very similar to last, with extreme suffering for some and others in a limbo of subdued normalcy.

Or there could be more volatility. Companies around the world are monitoring whether the new outbreak in southern China affects the port terminals there. Across Asia, sluggish vaccine rollouts could also open the door to spiraling barriers that are inflicting new damage on economies, ousting political leaders and changing the dynamics of power between nations.

The risks are rooted in decisions made months ago, before the pandemic caused the worst of the carnage.

Since the spring of last year, the United States and several countries in Europe have been betting heavily on vaccines, accelerated approval, and spending billions to secure the first batches. The need was urgent. In the United States alone, thousands of people died each day at the height of its outbreak when the country’s epidemic was catastrophically failed to manage.

But in countries like Australia, Japan, South Korea, and Taiwan, infection rates and deaths have been kept relatively low by border restrictions, public compliance with antivirus measures, and widespread testing and contact tracing. With the virus situation largely under control and the ability to develop vaccines domestically limited, there was less of a need to place huge orders or believe in solutions that were not yet proven at the time.

“The perceived threat to the public was low,” said Dr. C. Jason Wang, Associate Professor at Stanford University School of Medicine who studied Covid-19 Policy. “And governments have responded to the public perception of the threat.”

As a virus control strategy, border controls – a preferred method across Asia – only go so far, added Dr. Wang added: “To end the pandemic, you need both defensive and offensive strategies. The offensive strategy is vaccines. “

Their introduction to Asia was defined by humanitarian logic (which nations around the world needed vaccines), local complacency, and raw power over pharmaceutical production and export.

Earlier this year, contract announcements with the companies and countries that control the vaccines appeared to be more frequent than actual shipments. In March Italy blocked the export of 250,000 doses of the AstraZeneca vaccine, which Australia had designated to control its own angry outbreak. Other deliveries were delayed due to manufacturing issues.

“Shipments of the vaccine you buy actually end up on the docks – it’s fair to say they don’t come close to meeting the purchase commitments,” said Richard Maude, senior fellow at the Asia Society Policy Institute in Australia.

Peter Collignon, a doctor and professor of microbiology at the Australian National University who worked for the World Health Organization, put it more simply: “The reality is that vaccine makers keep them to themselves.”

In response to this reality and the rare blood clot complications that have arisen with the AstraZeneca vaccine, many politicians in the Asia-Pacific region have tried early on to stress that there is little rush.

The result is now a huge gap between the United States and Europe.

In Asia, around 20 percent of people have received at least one dose of a vaccine; in Japan, for example, only 14 percent. In France, on the other hand, it is almost 45 percent, in the USA more than 50 percent and in Great Britain more than 60 percent.

Instagram, on which Americans once scolded Hollywood stars for enjoying a mask-free life in Zero Covid Australia, is now littered with images of grinning New Yorkers hugging their vaccinated friends. While snapshots from Paris show smiling guests in cafes wooing summer tourists, people in Seoul are obsessive about refreshing apps that locate leftover cans and usually can’t find anything.

“Does the leftover vaccine exist?” a Twitter user recently asked. “Or did it disappear in 0.001 seconds because it’s like a ticket for the front row seat at a K-Pop Idol concert?”

Demand has increased as some of the supply bottlenecks have started to ease.

China, struggling with hesitation about its own vaccines after months of controlling the virus, administered 22 million vaccinations on June 2, a record for the country. Overall, China has reported having administered nearly 900 million doses in a country of 1.4 billion people.

Japan has also stepped up its efforts and relaxed the rules that only allowed select medical professionals to give vaccinations. The Japanese authorities opened large vaccination centers in Tokyo and Osaka and expanded vaccination programs to workplaces and universities. Prime Minister Yoshihide Suga now says all adults will have access to a vaccine by November.

In Taiwan, too, vaccination efforts recently got a boost when the Japanese government donated around 1.2 million doses of the AstraZeneca vaccine.

But all in all, Taiwan’s experience is somewhat typical: it has still only received enough doses to vaccinate less than 10 percent of its 23.5 million residents. A Buddhist association recently offered to buy Covid-19 vaccines to expedite the island’s anemic vaccination efforts, but it was told that only governments can make such purchases.

And with vaccinations lagging across Asia, so will any robust international reopening. Australia has signaled that it will keep its borders closed for another year. Japan is currently banning almost all non-residents from entering the country, and an intensive review of overseas arrivals in China has left multinational corporations without key workers.

The immediate future of many places in Asia seems likely to be one of hectic optimization.

China’s response to the Guangzhou outbreak – testing millions of people within days, closing entire neighborhoods – is a quick replay of dealing with previous outbreaks. Few in the country expect this approach to change anytime soon, especially since the Delta variant that devastated India is now in circulation.

At the same time, vaccine holdouts are facing increased pressure to get vaccinated before the available doses are up, and not just in mainland China.

Indonesia has threatened residents with fines of around $ 450 for refusing vaccines. Vietnam has responded to its recent surge in infections by soliciting donations from the public to a Covid-19 vaccine fund. And in Hong Kong, officials and business leaders are offering a range of incentives to alleviate severe vaccination hesitation.

Still, the prognosis for much of Asia this year is obvious: the disease has not been defeated and will not be in the foreseeable future. Even those lucky enough to get a vaccine often leave with mixed feelings.

“This is the way out of the pandemic,” said Kate Tebbutt, 41, a lawyer who received her first shot of the Pfizer vaccine last week at the Royal Exhibition Building near Melbourne’s central business district. “I think we should be further ahead than we are.”

Coverage was contributed by Raymond Zhong in Taipei, Taiwan, Ben Dooley in Tokyo, Sui-Lee Wee in Singapore, Youmi Kim in Seoul, and Yan Zhuang in Melbourne, Australia.

Categories
Politics

Biden’s Decide to Lead ATF Seems Earlier than Senate Panel

David Chipman, President Biden’s election to head the Alcohol, Tobacco, Firearms and Explosives Bureau, faced waning criticism from Republicans during his confirmation hearing Wednesday of his history of scathing comments on gun ownership.

Mr. Chipman, a two-decade veteran of the ATF who advised gun control groups, was selected in part because of his willingness to face an industry that has handcuffed the agency that enforces gun laws.

But his comments – including an interview last year in which he jokingly compared frantic gun purchases during the coronavirus pandemic to a zombie apocalypse – have been the subject of repeated questions from Republicans on the Senate Judiciary Committee.

“Many see it as a dedicated gun control advocate like David Chipman, who is in charge of ATF, a tobacco manager who is in charge of the Department of Health and Human Services, or Antifa, who is in charge of the Portland Police Department “said Senator Charles E. Grassley, Republican of Iowa and the senior committee member.

As the hearing began, news reports of a fatal shooting in San Jose, California began pinging on lawmakers’ phones. “I’m not lost that there is another mass shooting,” said Senator Amy Klobuchar, a Minnesota Democrat.

The National Rifle Association launched a coordinated campaign against Mr. Chipman’s nomination, citing his promises to regulate automatic weapons and his support for universal background checks.

The organization has effectively exercised a veto power over the appointment of stable leadership at the ATF and blocked several potential directors, including a conservative police union official who was tapped by President Donald J. Trump. The gun lobby has also waged a decades-long campaign to fight the ATF, fighting against fund increases and efforts to modernize their paper-based firearms tracking system.

Republicans said Mr. Chipman’s penchant for provocation made him an unacceptable choice in hopes of sinking his nomination, just as a story of inflammatory Twitter posts doomed Neera Tanden’s nomination, Mr. Biden’s first choice, to be his Head of household office.

Senator Mike Lee, Republican of Utah, barbecued Mr. Chipman for jokingly said in an interview last year that some first-time gun buyers were “preparing for end-time scenarios and zombie apocalypses.”

Mr Chipman, who appeared to be trying to avoid back and forth with Republicans, said the statements were “self-deprecating”. He also diverted questions about his advocacy of progressive politics by saying he considers himself a “policeman”.

Minutes later, after Texas Republican Senator Ted Cruz criticized him for calling for restrictions on AR-15-style rifles, Mr. Chipman thanked the Senator for telling me “me a Dr. Pepper offered ”.

Mr Biden elected Mr Chipman after a lobbying campaign by gun safety organizations led by former representative Gabrielle Giffords. For the past several years, Mr. Chipman has worked with groups led by Ms. Giffords and Michael R. Bloomberg, former Mayor of New York City, who also urged his selection.

The White House was initially reluctant to nominate anyone who would provoke such fierce opposition, but Mr Biden decided he had to take a risk after the mass murders in Atlanta and Boulder, White House officials said.

White House officials believe Mr Chipman has just enough votes – they estimate 50-52 – to overcome near-unanimous Republican opposition.

Two critical Democrats, Senators Joe Manchin III from West Virginia and Kyrsten Sinema from Arizona, have told Democratic leaders that if the hearings go well, they will likely vote for him. Two Republicans, Senators Susan Collins from Maine and Patrick J. Toomey from Pennsylvania, haven’t ruled out their support.

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Gustavo Dudamel, Celebrity Conductor, Is to Lead Paris Opera

Neef pointed out that Yannick Nézet-Séguin, 46, music director of the Met since 2018, did not start with an enormous repertoire there either. “The question isn’t about the crowd,” Neef said. “And these things are a bit deceiving: if you look at the list of operas that Gustavo has conducted, then from Mozart to John Adams. He conducts opera as long as he conducts symphonic music. “

When asked which works he was looking forward to the most, Dudamel replied: “Everything.” In Paris this autumn he is to conduct Puccini’s “Turandot” and Mozart’s “Le Nozze di Figaro”. In addition to the mainstream repertoire, he hoped to work with living composers from Europe and North and South America, including Adams, Thomas Adès and Gabriela Ortiz.

He added that he would like to direct the Paris Opera Ballet, the company’s in-house dance company. Dudamel said his mentor, José Antonio Abreu, the founder of El Sistema, often took him to ballet to learn about conducting.

“It was part of my training,” he said. “Also for my way of seeing the music.”

His appointment will include significant travel between Paris and Los Angeles, but his engagement with the Philharmonic is one that Dudamel said he has no intention of limiting. “I will share my time between the two families,” he said. What he will be limiting is guest conducting, a process he started a few years ago to shift his focus to longer-term projects.

“We’ll organize it the way he works in LA,” said Neef. “Long periods that stick together instead of traveling a lot.”

Neef added that Dudamel would provide a charismatic and visible link between the company’s main productions and its educational endeavors. In Los Angeles, Dudamel has contributed to the solid educational offering of the Philharmonic, particularly the Youth Orchestra Los Angeles, a program inspired by El Sistema and founded in 2007.

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World News

India shares lead losses in Asia-Pacific; Alibaba shares in Hong Kong surge

SINGAPORE – Stocks in India fell as stocks in Asia Pacific traded lower on Monday.

Both the Nifty 50 and BSE Sensex in India fell more than 2% each on Monday morning.

The losses came when the Covid-19 situation in the country remained severe. Reuters reported that the hardest-hit state of Maharashtra is considering a lockdown.

Meanwhile, stocks in mainland China also fell as the Shanghai compound fell 0.81% while the Shenzhen component fell 1.72%. Hong Kong’s Hang Seng Index fell 0.98%.

In Japan, the Nikkei 225 fell 0.52% while the Topix index was below the flatline. South Korea’s Kospi bucked the trend, rising 0.03%.

Australian stocks were down as the S & P / ASX 200 lost 0.45%.

The broadest MSCI index for stocks in the Asia-Pacific region outside Japan fell 1.19%.

Stocks in motion

Currencies and oil

The US dollar index, which tracks the greenback versus a basket of its peers, stood at 92.251 after falling above 92.8 earlier this month.

The Japanese yen was trading at 109.54 per dollar, stronger than above 110.5 against the greenback last week. The Australian dollar changed hands at $ 0.7608 after last week’s turbulent trading as it rose from over $ 0.765 to around $ 0.759.

Oil prices barely changed on the morning of trading hours in Asia. The international reference Brent crude oil futures rose slightly to $ 62.99 per barrel. The US crude oil futures were slightly higher at $ 59.37 a barrel.

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Business

Carl Icahn names former GE exec Kekedjian to guide Icahn Enterprises: WSJ

Carl Icahn speaks at Delivering Alpha in New York on September 13, 2016.

David A. Grogan | CNBC

Carl Icahn has named former General Electric CEO Aris Kekedjian to head his eponymous investment firm Icahn Enterprises, the billionaire businessman told the Wall Street Journal in an interview published on Sunday.

Kekedjian, GE’s chief investment officer until 2019, will take over as chief executive and chief operating officer of Icahn Enterprises on Monday, Icahn said.

Keith Cozza, the company’s current CEO, and SungHwan Cho, the company’s chief financial officer, are leaving, Icahn said. One reason for the departure is the company’s move from New York to Florida. The newspaper reported that Icahn Enterprises will appoint a new CFO at an unspecified date in the future.

Icahn Enterprises and Kekedjian did not immediately return requests for comments from CNBC.

Icahn Enterprises is a holding company with significant investments in energy, automobiles, real estate, and other sectors.

The company is publicly traded and has a market capitalization of more than $ 13 billion. Icahn, 85, chairman of Icahn Enterprises, is expected to eventually hand over the reins of the company to his son Brett.