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Health

Moderna says Covid vaccine exhibits promise in a lab setting towards variants, together with delta

A healthcare worker prepares a dose of Moderna Inc.’s Covid-19 vaccine on Tuesday February 9, 2021 at the Pacheco Vaccination Center in Brussels, Belgium.

Geert Vanden Wijngaert | Bloomberg | Getty Images

Moderna said Tuesday that its Covid-19 vaccine showed promise against coronavirus variants, including the highly contagious Delta variant, first identified in India in a laboratory setting.

The two-dose mRNA vaccine produced neutralizing antibodies against Delta as well as Beta and Eta, variants that Moderna said were first found in South Africa and Nigeria, respectively.

The company said the results were based on blood serum from eight participants one week after receiving the second dose of the vaccine. The data has not yet been reviewed by experts. The results, while promising, may not reflect how the vaccines actually perform against the variants in real-world scenarios.

Moderna shares rose more than 4% in intraday trading after the lab results were announced.

“We continue to strive to investigate new variants, generate data and share them as they become available,” said Stephane Bancel, CEO of Moderna, in a press release. “These new data are encouraging and reinforce our belief that the Moderna COVID-19 vaccine should continue to protect against newly discovered variants.”

Moderna’s update comes days after World Health Organization officials urged fully vaccinated people to continue wearing masks, maintain social distance, and practice other pandemic safety measures as the delta spreads rapidly across the world.

Delta, now present in at least 92 countries including the United States, is expected to become the predominant variant of the disease worldwide. In the US, the prevalence of the variant doubles about every two weeks.

WHO officials said Friday that they are urging fully vaccinated people to continue to “play it safe” as much of the world remains unvaccinated and highly contagious variants like Delta spread in many countries and cause outbreaks.

The comments were a departure from the Centers for Disease Control and Prevention, which said fully vaccinated Americans can be maskless in most environments.

“People can’t feel safe just because they got the two doses. They still need to protect themselves,” said Dr. Mariangela Simao, WHO Deputy Director General for Access to Medicines and Health Products, during a press conference.

Approved vaccines from Moderna, Pfizer-BioNTech, and Johnson & Johnson have been shown to be highly effective in preventing Covid, particularly against serious illness and death.

Some variants, including Delta, have shown the vaccines to be slightly less effective, and WHO officials said they fear people vaccinated could become part of the chains of transmission.

The Wall Street Journal reported Friday that about half of the adults infected in a Delta variant outbreak in Israel were fully vaccinated with the Pfizer vaccine, prompting the local government to reintroduce indoor masking and other measures.

In the United States, President Joe Biden warned that unvaccinated people are particularly at risk of contracting Delta.

He said the number of Covid deaths would continue to increase across the country due to the spread of the “dangerous” variant, calling this a “serious concern”.

“More than six hundred thousand Americans have died, and with this variant of the Delta, you know there will be others too. You know it will happen. We need to vaccinate young people,” Biden said Thursday at a community center in Raleigh, NC

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World News

Outages at Reddit and international information websites together with FT, New York Occasions and Bloomberg

Reddit co-founder Alexis Ohanian.

Jerod Harris | Getty Images

Reddit and global news sites like the Financial Times, New York Times and Bloomberg experienced intermittent outages Tuesday morning that left some users unable to access the sites.

Some visitors to the UK and US websites received an “Error 503 Service Unavailable” message.

Amazon, Twitter, PayPal, Spotify, Twitch, the BBC and The Guardian were also reportedly affected. Tech site The Verge is using an open Google Doc to cover the story, even though they forgot to turn off editing.

Initial reports of the outage began around 6 a.m. ET, but the sites were mostly back online to users an hour later. However, some websites, including the UK government website, gov.uk and the New York Times, experienced slow load times and graphics issues.

US cloud computing service provider Fastly said on its website at 5:58 a.m. ET that it is investigating a technical problem. At 6:44 am ET, Fastly said the problem had been identified and “a fix will be implemented”. At 8:41 a.m. ET, Fastly said the problem was resolved. Fastly stock lost 1.6% in pre-trading hours after the default began. At one point it was down about 3%.

Fastly operates a content delivery network. A CDN is a network of servers and data centers around the world that enables the transfer of assets necessary to load Internet content such as HTML pages, JavaScript files, images, and videos.

The infrastructure that underlies much of the Internet is operated by relatively few companies. If either of them has a problem, it can lead to widespread global outages affecting billions of people.

“That happens when half of the internet relies on Goliaths like Amazon, Google and Fastly for all servers and web services,” said Gaz Jones, technical director of digital agency Think3, in a statement. “The entire internet is dangerously aimed at just a few players.”

When Amazon’s cloud computing division, Amazon Web Services, ran into a problem in 2017, some of the world’s largest websites across the US east coast went offline for hours. In 2019, Cloudflare, another CDN company, had an issue that lasted about an hour and affected sites like the chat service Discord and the dating site OKCupid.

Toby Stephenson, chief technology officer for IT and cybersecurity firm Neuways, agreed that the incident “underscores the dependence of many of the world’s largest websites on content delivery networks.”

“Because there are so few of these CDN services, these outages can happen from time to time,” he said. “Using these CDNs to deliver content to readers makes these sites usually fast and responsive, but on that occasion they were left with an egg in their face. The tech backends of these large sites are probably fine, but they are Front ends that cannot be accessed and content cannot be transferred because the network has failed. “

Categories
Politics

Nationwide Guard mobilized for 30 days, together with Biden inauguration

DC National Guard Guardsmen stand in front of the U.S. Capitol in Washington, DC on January 7, 2021.

John Moore | Getty Images

WASHINGTON – Army Secretary Ryan McCarthy said Thursday that intelligence law and defense officials were “everywhere” prior to the uprising that rocked Washington.

“There were estimates of 80,000, there were estimates of 20-25. So back to sheer intelligence. It was all across the board,” McCarthy explained when asked about crowd control preparations.

“It has been very difficult to make that decision about what you’re up against,” he told reporters on a phone call, adding that the Department of Defense relies on law enforcement threat assessments.

By the weekend, 6,200 National Guard employees will be stationed in the country’s capital and will stay in the region for at least 30 days. The month-long mobilization ensures that members of the National Guard will be present for President-elect Joe Biden’s inauguration on January 20.

The unarmed forces will monitor traffic checkpoints and assist in law enforcement, while authorities work to secure the perimeter of the Capitol the day after the storm by a mob supporting President Donald Trump.

Pro-Trump supporters storm the U.S. Capitol following a rally with President Donald Trump on January 6, 2021 in Washington, DC.

Samuel Corum | Getty Images

The mobilization comes as the nation processes Wednesday’s surprise uprising that killed at least four people. All four living former presidents have condemned the day’s events, where a violent mob discouraged lawmakers from the typically superficial process of formally confirming Biden’s victory.

The DC National Guard was mobilized during the riot and about 1,100 soldiers were deployed to assist local police in containing the insurgency, the Pentagon said. The operation came after Washington DC, Mayor Muriel Bowser and House Speaker Nancy Pelosi requested the force, two sources told NBC News.

Virginia Governor Ralph Northam, Maryland Governor Larry Hogan, and New York Governor Andrew Cuomo announced all plans to send National Guard troops to DC as well.

Trump, who spoke at a rally to protest the election results just before his supporters infiltrated Congress, has still not condemned the unrest or defeat.

He encouraged protesters to be peaceful after storming the Capitol.

Pro-Trump protesters storm the U.S. Capitol to contest the certification of the 2020 U.S. presidential election results at the U.S. Capitol in Washington, DC on January 6, 2021.

Ahmed Gaber | Reuters

The President continued to raise unsubstantiated allegations of electoral fraud, despite the findings of the Justice and Homeland Security Ministries to the contrary.

It is typical for the National Guard to be present at the inaugurations, and in 2017 more than 7,000 soldiers were mobilized for Trump’s inauguration.

Biden’s inauguration is expected to look very different from previous ceremonies due to public health precautions.

Biden and Vice President-elect Kamala Harris will take their oath of office at the Capitol on Jan. 20, but have otherwise changed tradition to adapt to the spreading coronavirus pandemic.

The Biden transition team has said it is reinterpreting the typical National Mall gathering and opening parade from the Capitol to the White House so that Americans can attend from home.

Biden condemned the riot on Wednesday in a national televised address.

“At this hour, our democracy is under unprecedented attack,” said the former vice president.

“It is chaos, it verges on turmoil and it has to end now. I call on this mob to pull back and do this democratic work,” added Biden.

The rioters’ success in breaking police barriers has raised questions about the security precautions being taken for the inauguration.

Senator Amy Klobuchar, D-Minn., Who is on the committee planning Biden’s inauguration, said on CBS News, “There needs to be big, thorough reviews of what happened and what changes have been made.”

Klobuchar added that the inauguration is a major security event every four years compared to the electoral college vote count, which generally takes place without incident.

“Here they had an event that normally has little historical note,” said Klobuchar.

CNBC’s Tucker Higgins reported from New York.

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Categories
Politics

Trump pardons 15, together with folks convicted in Mueller probe

President Donald Trump on Tuesday apologized to 15 people, including two men convicted in the investigation by Special Envoy Robert Mueller and four former Blackwater US guards convicted of the 2007 murders of 14 unarmed Iraqi civilians in Baghdad.

Others who received pardons included two former Republican congressmen who admitted to having committed financial crimes.

Trump also commuted all or some of the criminal convictions of five other people as the president is nearing his final month in office.

One such person, Philip Esformes, owner of a health facility in South Florida, was sentenced to 20 years in prison in September 2019 for “the largest healthcare fraud ever indicted by the Justice Department”. Esformes, 52, is now being released from prison for Trump’s action.

Trump, who has sharply criticized Muller’s investigation into his 2016 campaign and its contacts with Russians, apologized to his former campaign foreign policy advisor, George Papadopoulos, who was convicted of making false statements during the investigation.

George Papadopoulos, former member of the foreign affairs committee of Donald Trump’s 2016 presidential campaign, poses for a picture before a television interview in New York, New York, the United States, on March 26, 2019.

Carlo Allegri | Reuters

“Today’s apology helps correct the injustice that Mueller’s team has done to so many people,” Trump’s press secretary Kayleigh McEnany said in a statement to Papadopoulous.

The president also pardoned Alex van der Zwaan, an attorney and Dutch national who pleaded guilty to lying to the FBI during the Mueller investigation. Van der Zwaan was the first person convicted in the investigation and was sentenced to 30 days in prison in 2018.

Alex van der Zwaan leaves the U.S. District Court after his conviction in Washington on April 3, 2018.

Leah Millis | Reuters

Four former Blackwater security companies, Nicholas Slatten, Paul Slough, Evan Liberty and Dustin Heard, who received pardons, opened fire on and around Nisur Square in Baghdad on September 16, 2007. According to the Justice Department, 14 civilians were killed, including two women and two boys, ages 11 and 9. At least 17 other victims were injured.

Slatten, who was convicted of murder, was released “without provocation,” according to the Justice Department. He has served a life sentence.

The other three men were convicted of manslaughter and other charges and were sentenced to 15 years in prison again last year, half of their original sentences.

In a statement, McEnany said that “the pardon for these four veterans has broad support from the public, including Pete Hegseth, a Fox News employee and a number of GOP Congressmen.

“In addition, prosecutors recently announced – more than 10 years after the incident – that the leading Iraqi investigator was heavily relied on by prosecutors to verify that there were no insurgent victims and to gather evidence , possibly had ties to insurgent groups herself, “McEnany said in her statement.

Other pardons include former California Congressman Duncan Hunter and New Yorker Chris Collins.

Former U.S. Representative Chris Collins (R-NY) is leaving federal court in New York City on October 1, 2019.

Drew Angerer | Getty Images

Collins, who last year pleaded guilty to crimes related to his son pointing to nonpublic information about a pharmaceutical company’s failed drug trial, was the first member of Congress to endorse Trump’s campaign as president in 2015. He served a 26-month sentence in October.

Hunter pleaded guilty to misusing campaign funds in 2019 along with his wife, who together converted and stole more than $ 250,000 over several years. He was due to serve an 11 month sentence next month.

Another fallen GOP member of Congress, Steve Stockman of Texas, had the remainder of his 10-year prison sentence for misusing donations that were converted by the President. Stockman, 64, had served more than two years in that tenure and signed Covid-19 that year.

Senator Richard Blumenthal, D-Conn., Condemned many of the pardons in a damning statement.

“I doubt government contractors who slaughtered civilians or slaughtered corrupt friends of Congress had the founders in mind when drafting the pardon,” said Blumenthal, a member of the Senate Judiciary Committee.

“Most despicable is that President Trump is twisting that presidential power to reward allies who have broken the law about his conduct,” he said. “Donald Trump is leaving the presidency as he accepted it: without a hint of respect for the constitution and as a complete shame for his office.”

Trump also pardoned two former U.S. border guards, Ignacio Ramos and Jose Compean, for their convictions for shooting and wounding an unarmed illegal alien who traded 700 pounds of marijuana in 2005. President George W. Bush had their sentences converted from 11 and 11 years to 12 years in 2009.

The pardons come after Trump refused to admit he lost the presidential election to Joe Biden, whose victory was confirmed by the electoral college last week. Trump’s loss sparked immediate speculation that he would reward allies and others with executive grace actions in his final weeks at the White House.

Trump has been particularly stingy when it comes to granting executive grace, which includes pardons and commutations, compared to previous presidents.

As of Tuesday, Trump had issued just 28 pardons and commuted the criminal convictions of 16 other people, a significantly lower rate than other one-year presidents, according to the Justice Department.

Trump’s pardons included those on financial scammer Michael Milken; Press Baron Conrad Black; former Arizona Sheriff Joe Arapaio, convicted of contempt of court; Lewis “Scooter” Libby, former advisor to ex-Vice President Dick Cheney on obstruction of justice; Conservative Gadfly Dinesh D’Souza for Campaign Submission Fraud; and Ex-New York Police Commissioner Bernie Kerik for Tax and Other Crimes.

In November, Trump apologized to his first national security adviser, Michael Flynn, for making false statements to FBI agents.

In July, Trump commuted the 40-month sentence of Republican adviser Roger Stone, who was convicted of lying to Congress.

Among the beneficiaries of his commutation was former Illinois Governor Rod Blagojevich, who tried to sell an appointment to the Senate seat vacated by Barack Obama when that president became president.

Trump previously apologized for several deaths, including early 20th century black boxing champion Jack Johnson for the crime of crossing the state line with his white girlfriend and Susan B. Anthony, the 19th suffragette, who was charged with illegal elections was convicted.

Trump also pardoned the late scientist Zay Jeffries, who was convicted of anticompetitive behavior by Sherman in 1948 for violating the antitrust law. That year, President Harry Truman awarded him the President’s Medal of Merit for his work during World War II, which included contributions to the Manhattan Project.

Trump pardoned Alice Marie Johnson, a woman convicted of conspiracy to distribute cocaine, in August. The president had commuted Johnson’s life sentence two years earlier after lobbying reality TV star Kim Kardashian West on her behalf.

The only other president with a term in office in the past 30 years, Trump’s Republican compatriot George HW Bush, pardoned 74 people by comparison and issued commutations for three more.

Obama, who served two terms before Trump, pardoned 212 people, or more than six times the number Trump pardoned in half that time. Obama commuted the sentences of more than 1,700 people.

The last Republican to serve two terms, George W. Bush, pardoned 189 people and commuted 11 sentences.