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Excessive Turnover at Nursing Properties Threatens Residents’ Care

Exceptionally high turnover among nursing home workers likely contributed to the shocking number of deaths in facilities during the pandemic, the authors of a new study suggested.

The study, published Monday in Health Affairs, a health policy journal, provides a comprehensive overview of turnover rates in 15,645 nursing homes across the country, taking into account nearly all federal government certified facilities. The researchers found that the average annual rate was 128 percent, with some facilities having sales in excess of 300 percent.

“It was really breathtaking,” said David Grabowski, professor of health policy at Harvard Medical School and one of the study’s authors. Researchers pointed to the results to urge Medicare to publish staff turnover rates at individual locations in nursing homes to highlight substandard conditions and pressure owners to make improvements.

Inadequate staffing – and low wages – have long plagued nursing homes and the quality of care for the more than one million residents who live in these facilities. However, the pandemic has exposed these issues even more sharply. Investigations are ongoing by some states to monitor the facilities as cases in Covid are uncontrolled and deaths have skyrocketed.

The high turnover rate likely made it harder for nursing homes to conduct strong infection controls during the pandemic and led to widespread spread of the coronavirus, said Ashvin Gandhi, lead author and health economist and assistant professor at the University of California Los Angeles Anderson School of Management.

Nursing home owners blame Medicaid, the state’s program for the care of the skilled elderly, for the inadequate reimbursement.

“Recruiting and retaining workers is one of the most pressing challenges facing long-term carers and we have been calling for help for years,” said Dr. David Gifford, chief medical officer of the American Health Care Association and the National Center for Assisted Living Trading Group, said in an email statement.

“It is high time providers were given the right resources to invest in our frontline caregivers to improve the quality of care,” he said.

At least 172,000 deaths from the virus had been reported among residents or employees of nursing homes and other long-term care facilities by the end of February, according to a database compiled by the New York Times. The death toll in nursing homes alone has caused more than a third of all Covid deaths in the United States, although mortality and case rates have fallen sharply as more than 70 percent of residents have received vaccinations.

Industry criticism has also centered on the decade-long ownership of nursing homes by private equity and other private investment firms, where profits for investors took precedence over residents’ welfare. These owners have long been accused of under-staffing their facilities and underpaid workers.

Updated

March 1, 2021, 9:49 p.m. ET

Labor is one of the primary costs of running a nursing home, said Dr. Gandhi. “It’s generally not a very high-margin industry,” he said. “Any institution trying to maximize its profits will think carefully about its staffing costs.”

Nursing home staff have also shown resistance to being vaccinated against the coronavirus, making it difficult for public health officials and nursing homes to provide comprehensive vaccination coverage for a single facility. If a vaccinated nurse leaves the hospital and is replaced, the facility must ensure that the new employee is vaccinated as well, especially given the reluctance of some workers to receive a coronavirus shot.

“Trying to get a single shot is not enough,” said Dr. Gandhi. “You need continuous vaccination work.”

Registered nurses, who are the most skilled workers, had the highest turnover rates, and turnover varied widely across institutions. The states with the highest rates included Oklahoma, Montana, and Kansas. Facilities with low star ratings on the Medicare website that compared nursing homes had the highest average sales and nursing homes with high ratings had the lowest sales. Revenue was also higher at for-profit organizations owned by chains that serve Medicaid beneficiaries, according to the study.

Melissa Unger, the executive director of SEIU 503, a division of the Service Employees International Union in Oregon, said nurses have difficulty working in facilities with too few employees to adequately care for residents.

“You don’t feel good about the work you do,” said Ms. Unger, noting that many of the employees are women and people of color. “They’re doing all of this for shitty benefits and low wages.”

Summer Trosko, a union member who works at a nursing home in Oregon, said she was used to colleagues leaving burnout because of under-staffing and lack of funds. “You get tired and just can’t take it anymore and stop,” she said. Many are being replaced with people who have just graduated from high school with little education, she said.

In addition to making turnover rates available to the public, the authors point out a number of steps lawmakers could take to improve retention. Medicare could include sales in its star rating system, and Medicare and Medicaid could reward nursing homes with higher rates when they had lower sales. “If we want to change nursing homes, we have to start with the staff,” said Dr. Grabowski.

Researchers used newly available payroll-based data collected by the Centers for Medicare and Medicaid Services for Registered Nurses, Licensed Practical Nurses, and Certified Nursing Aides to calculate turnover rates in 2017 and 2018. They looked at the percentage of hours a care worker worked in a given year and calculated higher rates if the person who left the company had done more care.

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New York well being chief defends state’s choice to make nursing houses take Covid sufferers

New York Health Commissioner Dr. Howard Zucker on Friday defended the state’s decision in March to force nursing homes to admit hospital residents with the coronavirus, blaming staff for spreading the virus.

The guideline, enacted on March 25, banned nursing homes from refusing admission or readmission to residents infected with Covid-19. The policy also banned nursing homes from testing patients prior to entry, NBC News reported. The policy was reversed later in May.

Zucker said Friday that at the time, the coronavirus hospitalization rate in New York was increasing “at an astounding rate” and capacity in the state’s intensive care units was running low. By allowing residents to return to the nursing homes, it helped protect the health system from collapse, he said.

“You can only verify a decision based on the facts you had at the time,” Zucker said during a press conference next to New York Governor Andrew Cuomo. “And with the facts we had at the time, it was the right decision from a public health perspective.”

Zucker said the decision was based on recommendations from the Centers for Disease Control and Prevention, issued at the time, that nursing homes should accept all residents who would normally accept them, including those diagnosed with Covid-19, for as long Precautions have been taken.

A CDC spokesman was not immediately available to comment on Zucker’s remarks.

“What if we hadn’t done it on March 25? Hospital beds, which ultimately saved lives, would not have been available because they would have been occupied by someone who could have been discharged,” Zucker said. “We made the right public health decision then and, given the same facts, we would make the same decisions again.”

The Covid-19 patients who returned to the nursing homes were likely not contagious according to the CDC’s guidelines at the time and were separated from other residents. Zucker added that state law requires nursing homes to refuse residents if they are unable to properly care for them.

“We simply said that you cannot refuse admission because of the Covid status,” he said. “We never said you had to accept, we said you couldn’t deny.”

The state’s top health official comes as the Cuomo government faces bipartisan criticism of the treatment of Covid-19 deaths in the nursing home. An investigation by New York Attorney General Letitia James published in late January found that the New York Department of Health signed up to 50% of deaths from Covid-19 in nursing homes.

On Friday, Cuomo and Zucker said most of the spread of the virus was not due to the Covid-positive resident, but from the staff who look after them.

“Covid came from the staff in the nursing homes. They got it at home, they got it at the supermarket, they went to work and they brought Covid with them,” Cuomo said.

However, Cuomo has aggressively defended the state’s census, stating that these deaths were counted as part of hospital deaths rather than nursing homes. The Democratic governor has apologized for “creating a void” by not providing enough information quickly enough and by not fighting against misinformation.

“Twitter, false reports, will eventually become a reality,” said Cuomo. “Social media, 24-hour news network, if you don’t correct it, it’ll repeat … and then people will think it’s true.”

In August, prosecutors under the Trump administration requested information about the deaths in New York nursing homes that Cuomo has criticized as politically motivated. The state legislature also asked for similar information, but the Cuomo government postponed that request to focus on that of the Justice Department, the governor said.

One of Cuomo’s top advisors, Melissa DeRosa, reportedly told Democratic lawmakers that the governor’s administration was “frozen” at their request because they feared the data would be used against them by the Justice Department, Associated Press reported.

DeRosa has since tried to clarify her comments, stating in a statement last week that she was trying to tell lawmakers that they need to focus on the Justice Department’s request first.

“We were comprehensive and transparent in our responses to the DOJ and had to immediately focus our resources on the introduction of the second wave and the vaccine,” DeRosa said in the statement. “As I said when I called the legislature, we weren’t able to respond to your request as quickly as anyone would have liked.”

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Business

Some use Ford F-150 hybrid vans to energy properties

Randy Jones, of Katy, Texas, was using his 2021 Ford F-150 to power space heaters and other appliances throughout his home when it lost power during the winter storm earlier this week.

Source: Randy Jones

When Randy Jones of Katy, Texas bought his new Ford F-150 pickup a few weeks ago, he didn’t think he’d use it to turn on the lights in his home during a historic winter storm that left millions without power.

The on-board generator of the 2021 Hybrid “gives you the opportunity to use your truck like a mobile generator”, which according to Ford can generate an output of up to 7.2 kW.

In a phone interview with CNBC on Thursday, 66-year-old Jones said he bought the truck due in part to that feature, adding that it frequently loses power due to hurricanes and other storms. When he lost power on Sunday evening, he decided to take out a couple of extension cords and put the generator to the test.

“Without them, I would have been in the dark and cold like everyone else in the neighborhood,” said the retired refinery worker, adding that he was helping the neighbors charge their phones and laptops. “Quite a few neighbors said, ‘Hey, I’ll get one’, like ‘I’ll trade my Dodge or GMC’ because we always have power in South Texas with hurricanes and things like outages.”

Jones said he used the truck’s on-board generator for three days to power appliances in his home until electricity was restored on Wednesday.

He is not alone. Jerry Hall, 73, bought his new F-150 in late January. It turned out to be perfect timing, he said.

“The truck saved the day,” the Kerrville, Texas resident said in a telephone interview Thursday. Hall said his house lost power from Sunday evening through early Thursday. “Without the truck it would have been three miserable days.”

Hall said he and his wife still spent those days without a heater, but they were able to run extension cords from the truck into the house to power lights, the refrigerator, television, and other luxuries.

“It connected us to the outside world,” he said.

Hall said “the main reason” he bought the truck was because of its on-board generator. He said last spring’s harsh weather had resulted in power outages in his part of the state, and he knew he wanted some kind of generator. It just makes sense to get a new truck with a built-in generator.

Other truck owners have posted similar stories on an online F-150 owner forum. Photos from the forum were posted on Twitter, where Ford CEO Jim Farley commented and tweeted: “The situation in the American Southwest is so difficult. I wish everyone in Texas had a new F150 with a PowerBoost generator on board …”

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Health

Scientific Trials Are Shifting Out of the Lab and Into Individuals’s Houses

When the pandemic hit last year, clinical trials were affected. Universities closed and hospitals focused on fighting the new disease. Many studies that required repeated personal visits to volunteers have been delayed or canceled.

However, some scientists found creative ways to continue their research even when the personal interaction was inherently risky. They sent medicines Tests conducted via video chat and asked patients to monitor their own vital signs at home.

Many scientists say this shift towards virtual studies is long overdue. If these practices persist, they could make clinical trials cheaper, more efficient and fairer, and provide cutting-edge research opportunities to people who otherwise would not have the time or resources to use them.

“We’ve found that we can do things differently and I don’t think we’ll be going back to the way we used to know,” said Dr. Mustafa Khasraw, a Medical oncologist and clinical trial specialist at Duke University.

According to one analysis, nearly 6,000 studies have been registered on ClinicalTrials.gov stopped between January 1 and May 31, roughly twice as many as in times without a pandemic.

For example, at Johns Hopkins University, researchers delayed their study of how adults ages 65 to 80 metabolized tenofovir, a drug used to prevent and treat HIV

“The idea of ​​recruiting older people who we know are at particular risk – recruiting them to answer a fundamental question that doesn’t immediately change care or affect their health – just didn’t seem like it what we should do, “said Dr. Namandje Bumpus, the pharmacologist leading the study, which is on hold.

In Flint, Michigan, researchers had to stop admitting emergency patients for a hypertension study. Other volunteers dropped out or were difficult to contact.

“Their phone service is down, or they have very different schedules, or they are harder to reach because they care about someone,” said Dr. Lesli Skolarus, a stroke neurologist at the University of Michigan who is leading the study.

Dr. Skolarus and her colleagues have continued the process, albeit with a few changes. Most importantly, they canceled their personal follow-up exams and instead asked participants to take blood pressure cuffs with them and send photos of the readings via SMS.

Other research teams made similar adjustments. Neurologists at Massachusetts General Hospital in Boston revised a pilot study of methylphenidate, the active ingredient in Ritalin, in seniors with mild dementia or cognitive impairment. Instead of going to the hospital every two weeks, study participants now receive their medication in the mail, take cognitive assessments via video conferencing, play brain games on their computers, and conduct daily surveys at home.

“In essence, it is now an entirely virtual study,” said Dr. Steven Arnold, the neurologist who led the study.

Updated

Apr. 18, 2021, 12:04 p.m. ET

Even when scientists can’t eliminate personal visits, they find ways to reduce them. When Lorraine Wilner, a 78-year-old retiree with metastatic breast cancer, first started a clinical trial at Duke University last summer, she had to take a three-hour drive to the Durham, NC campus every four weeks for blood tests and occasionally other tests. She said she always left with a full gas tank. “So I don’t have to stop at a gas station or touch things or go to places where half of the people don’t wear a mask,” she said.

She can now have her blood drawn at a laboratory near her home in Lancaster, SC. The researchers then review the results with her over a video call. She still has to drive to Duke for regular scans, but the reduced travel has been a huge relief. “It makes it a lot more convenient,” she said.

Distance learning is likely to continue in a post-pandemic period, researchers say. Reducing face-to-face visits could make patient recruitment easier and lower dropout rates, which could lead to faster and cheaper clinical trials, said Dr. Ray Dorsey, a neurologist at the University of Rochester who has done remote research for years.

In fact, its inclusion in one of his recent virtual studies tracking people with a genetic predisposition to Parkinson’s actually spike this past spring. “While most clinical trials were suspended or delayed, ours accelerated amid the pandemic,” he said.

Moving to virtual trials could also help diversify clinical research and encourage low-income and rural patients to enroll, said Dr. Hala Borno, oncologist at the University of California at San Francisco. The pandemic, she said, “really allows us to step back and reflect on the burdens we have placed on patients for a long time.”

Virtual trials are not a panacea. Researchers need to ensure that they can thoroughly monitor the volunteer’s health without personal visits and be aware of the fact that not all patients have access to or are familiar with technology.

In some cases, scientists have yet to demonstrate that remote testing is reliable. While Dr. Arnold is optimistic that home cognitive testing could offer a better window into how his patients work on a daily basis, he noted that environments at home are uncontrolled. “Maybe a cat is crawling on you or grandchildren in the next room,” he said.

There is also the unpredictable nature of human behavior. Dr. Brennan Spiegel, gastroenterologist and director of health research at Cedars-Sinai Health System, often uses Fitbits to remotely monitor subjects. But one participant once put the device on a dog. A few others sent their Fitbits through the laundry. “You suddenly get a lot of steps – thousands and thousands of steps,” he said.

And some treatments may not work as well remotely. Last January, Clay Coleman Jr., a 61-year-old Chicago resident, took part in a clinical trial to treat his peripheral artery disease, which caused severe pain with every attempt to walk. “It was very difficult,” said Mr. Coleman, who is not driving. “My legs are very important to me because this is how I get around.”

He hoped the study of taking blood pressure medication and participating in a supervised exercise program could get him back in shape. Three times a week he traveled to a local gym for a structured treadmill workout with an instructor. “I was there maybe six weeks before this virus thing came up,” he said.

Suddenly the gym was out. Instead, Mr. Coleman’s trainer called him regularly and encouraged him to keep moving.

Dr. Mary McDermott, a The general internist at Northwestern University running the study isn’t sure how effective this type of remote coaching will be. “We cannot assume that remote intervention will be the same,” she said. “Or that remote measurements replace everything we have personally done.”

Still, the pandemic has shown that there is room for reform. Dr. Deepak Bhatt, a cardiologist at Brigham and Women’s Hospital in Boston, is part of a team that will start a study of an injectable blood thinner later this year. After the first personal visit to the doctor, the appointments are virtual.

“I’m pretty sure if Covid hadn’t occurred we would have done things the usual way,” he said. Sometimes he added, “It takes a crisis to provoke change.”

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Health

Nursing properties with extra minority residents had extra Covid deaths: Examine

Derede McAlpin is holding a photo of her mother, Sara McAlpin, 92, who was diagnosed with Covid-19 in Rockville, MD.

Katherine Frey | The Washington Post | Getty Images

Nursing homes with more minority residents reported more than three times as many deaths in Covid as those with more white residents, a large study published on Wednesday found.

The University of Chicago researchers examined 13,312 U.S. nursing homes and analyzed Covid data reported to the Centers for Disease Control and Prevention from May through December. They found that nursing homes where more than 40% of their residents were black or Spanish reported 3.3 times as many deaths and cases in Covid as nursing homes with more white residents.

Nursing homes and other long-term care facilities are hardest hit by the pandemic. Less than 1% of Americans live in such facilities, according to the CDC, but they have caused nearly 40% of all deaths in the United States, according to the COVID Tracking Project.

It is well documented that the pandemic has disproportionately affected the ethnic and racial minorities in the United States. President Joe Biden and his administration have vowed to ensure justice throughout the vaccine distribution process and to prioritize color communities disproportionately affected by the pandemic.

The new study, published on JAMA Network Open, shows how these differences affect nursing homes and has policy implications for vaccine distribution.

The differences were due to some historical factors, the researchers said. For example, minority residents in nursing homes are more likely to live in large facilities that are for-profit, rely more on Medicaid, and “have shortcomings in care,” the researchers said. They added that “Nursing homes in the US are very segregated”

An Empress EMS paramedic loads a suspected COVID-19 patient into an ambulance on April 7, 2020 in Yonkers, New York.

John Moore | Getty Images

“Before the COVID-19 pandemic began, racial differences in the quality of home care were known to be common,” the authors wrote. “Compared to whites, blacks are more likely to be admitted to the lowest quality nursing homes that have lower nursing staffing rates, more serious regulatory deficiencies, and a higher likelihood of being excluded from the Medicaid program.”

The researchers, health economists Rebecca Gorges and Tamara Konetzka, added that the pandemic is a “perfect storm” for residents of nursing homes.

“With minority communities having the highest COVID-19 infection rates and nursing homes in these communities generally being of lower quality, non-white nursing home residents are in the eye of this perfect storm,” they wrote.

The study finds that the death toll of Covid in U.S. nursing homes is likely to decline soon with the introduction of the vaccine. The CDC recommends that states give the vaccine to residents and long-term care workers as a priority before moving on to other segments of the population.

The Federal Pharmacy Partnership for Long-Term Care program allowed states to tap into pharmacies like CVS and Walgreens to help distribute the vaccine. As part of that program, more than 5 million doses have been given to residents and long-term care workers since Tuesday, according to the CDC.

“As vaccination progresses, it will be important for policy makers to consider existing inequalities to ensure that the vaccine distribution process includes a special effort to reach color communities,” the researchers wrote in the study.

They noted some limitations to their study. Institution-level data is publicly available through the CDC, but comprehensive individual-level data is not available. Such data “is needed to understand whether there are intra-facility differences in addition to differences between facilities,” they said.

They added that as of May, the data they analyzed were reported by nursing homes themselves, omitting many of the cases and deaths that had previously occurred. And they said the federal data “didn’t allow any racial classifications other than white, black, and Hispanic.” More detailed data would have enabled further analysis of the data across different racial groups.

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States within the US are Pulling Again Vaccine Doses from Federal Program for Nursing Houses

It wasn’t long before Keith Reed, an assistant health commissioner in Oklahoma, discovered a major logistical problem with the introduction of state vaccination. Week after week, Oklahoma allocated thousands of valuable doses to a federal program for nursing home patients who did not all use them. Indeed, Tens of thousands of cans sat untouched in freezers.

So his department rang an acoustic signal. It was decided to stop allocating vaccines from Oklahoma to the federal program, a partnership with private pharmacies like CVS and Walgreens to immunize residents of long-term care facilities. Instead, they would go to distribution channels that would get them into people’s arms faster.

A number of states have taken similar steps to divert care from the federal effort known as the Pharmacy Partnership for Long-Term Care Program. This is a vivid example of how chaotic the US vaccination effort has been. Some of the other states are Minnesota, Maine, Michigan, Missouri, and Ohio.

Reed said moving to Oklahoma would do no harm: Walgreens and CVS have assured him that all nursing home residents in the state who needed and wanted to be vaccinated would have the first of their two shots by the end of the week.

The federal program used a formula that made it clear how many shots would be required for long-term care facilities like nursing homes, whose residents are particularly vulnerable to the coronavirus. Another problem has arisen: a significant number of residents, and particularly workers in the facilities, are reluctant to be vaccinated.

A study published Monday by the Centers for Disease Control and Prevention found that 77.8 percent of residents and 37.5 percent of workers received the vaccine in an average long-term care facility in the first month of the program. The study says the real rate may be higher for workers as some may have been vaccinated in different settings. Even so, federal officials are particularly concerned about how many workers oppose vaccination and have stepped up efforts to change their minds.

Mr Reed said the doses Oklahoma took away from the federal program will go to thousands of Oklahomans who are 65 years or older and do not live in nursing homes.

“Our goal is to get the vaccine into someone else’s arms within seven days of receiving it from the freezer,” Reed said in an interview last week. “We just had a tough time with this amount of vaccines that were earmarked for this program when we could use this vaccine to go straight to Oklahomans.”

Nursing home residents’ advocates are watching closely for signs that the moves will hamper their vaccinations.

“If we find older adults are not getting the vaccines they need, that’s our business,” said Lisa Sanders, a spokeswoman for LeadingAge, which represents more than 5,000 nonprofit aging service providers.

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Cuomo administration underreported Covid deaths in nursing houses, report says

A view of a patient being rolled out of a nursing home in Flushing Queens New York USA during the coronavirus pandemic on April 22, 2020.

John Nacion | NurPhoto | Getty Images

The New York Department of Health reported Covid-19 deaths in nursing homes by up to 50%, according to a new report released Thursday by New York Attorney General Letitia James.

The 76-page report comes from a month-long investigation by the Attorney General’s office into allegations that nursing homes have failed to follow coronavirus safety protocols. Her office also investigated discrepancies between the number of deaths reported by the state Department of Health in nursing homes and the number of deaths reported by the facilities themselves.

The investigation found that the number of Covid deaths among nursing home residents in some facilities has increased by more than 50% after counting residents who died in the hospital. The official Covid-19 state death toll in nursing homes excludes patients who have died after being transported to hospital.

Democratic Governor Andrew Cuomo has been criticized for failing to disclose the total number of nursing home residents who have died from Covid-19. In her comprehensive report, James, also a Democrat, noted that “many nursing home residents in hospitals died of Covid-19 after being transferred from their nursing homes, which is not reflected in the overall data on nursing home deaths published by DOH . “

Cuomo representatives did not immediately respond to CNBC’s request to comment on the results. Representatives from the state Department of Health also did not respond to CNBC’s request for comment.

The attorney general’s findings put them directly in conflict with the governor, who often boasted of the state’s response to the coronavirus. Cuomo has also dismissed criticism of a policy by the Ministry of Health that directed nursing homes to accept residents who tested positive for the coronavirus. The governor has repeatedly defended his government’s response to the pandemic, stating that the state was poorly supported by an inept federal government that was caught by surprise by importing the virus.

In May, the federal government asked nursing homes to provide weekly data on deaths from the coronavirus, including those who died at the facility and in hospitals. However, that guideline came after the first peak of the New York outbreak, making the data available from the state nursing homes barely available. An Associated Press analysis of federal data released in August found the state could underestimate deaths by up to 65%.

James’ results are based on a survey of 62 nursing homes, or approximately 10% of nursing homes in the state. She said her law firm is continuing to investigate inconsistencies in the data reported by the Ministry of Health and the numbers reported to the Attorney General.

The investigation also found that a number of nursing homes did not adhere to “Critical Infection Control Guidelines”; B. Failing to isolate residents who test positive for the virus.

“As the pandemic and our investigation continue, it is imperative that we understand why New York nursing home residents have suffered needlessly so alarmingly,” James said in a statement. “While we cannot bring back the people we lost to this crisis, this report aims to provide transparency the public deserves and encourage increased action to protect our most vulnerable residents.”

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Eli Lilly Claims Drug Prevents Coronavirus An infection in Nursing Houses

An unusual experiment to prevent nursing home employees and residents from being infected with the coronavirus is successful, drug manufacturer Eli Lilly announced on Thursday.

A drug containing monoclonal antibodies – laboratory-bred virus fighters – prevented symptomatic infections in residents who have been exposed to the virus, even in the frail elderly, who are most vulnerable. This is based on preliminary results from a study conducted in collaboration with the National Institutes of Health.

The researchers found an 80 percent reduction in infections in residents who received the drug compared to those who received a placebo and a 60 percent reduction in staff, results that were very statistically meaningful, Eli Lilly said.

The data has not yet been reviewed or published by experts. The company expects to present the results at a future medical meeting and publish them in a peer-reviewed journal, but did not say when.

The study included 965 participants in nursing homes: 666 employees and 299 residents. (The company had hoped more residents would attend, but it proved difficult to enroll. Many had dementia and others were suspicious of intravenous medication.)

There were four deaths from Covid-19 among study participants. All of them were among those living in nursing homes who were given a placebo, not the drug.

The drug Bamlanivimab already has an emergency approval from the Food and Drug Administration, which enables Eli Lilly to make it available to symptomatic patients early in the course of their infection.

However, this study asked if the drug could stop infections before they started. It was an unusual experiment: medical staff rushed to nursing homes in trucks equipped with mobile laboratories as soon as a single infection was found there. Once the workers arrived, they set up temporary infusion centers to administer the drug.

The research ended that weekend with an emergency meeting of the Data Protection and Monitoring Committee, an independent group that oversees the incoming results. The data was strong and convincing enough to bring the placebos to a halt.

Covid19 vaccinations>

Answers to your vaccine questions

If I live in the US, when can I get the vaccine?

While the exact order of vaccine recipients may vary from state to state, most doctors and residents of long-term care facilities will come first. If you want to understand how this decision is made, this article will help.

When can I get back to normal life after vaccination?

Life will only get back to normal once society as a whole receives adequate protection against the coronavirus. Once countries have approved a vaccine, they can only vaccinate a few percent of their citizens in the first few months. The unvaccinated majority remain susceptible to infection. A growing number of coronavirus vaccines show robust protection against disease. However, it is also possible that people spread the virus without knowing they are infected because they have mild symptoms or no symptoms at all. Scientists don’t yet know whether the vaccines will also block the transmission of the coronavirus. Even vaccinated people have to wear masks for the time being, avoid the crowds indoors and so on. Once enough people are vaccinated, it becomes very difficult for the coronavirus to find people at risk to become infected. Depending on how quickly we as a society achieve this goal, life could approach a normal state in autumn 2021.

Do I still have to wear a mask after the vaccination?

Yeah, but not forever. The two vaccines that may be approved this month clearly protect people from contracting Covid-19. However, the clinical trials that produced these results were not designed to determine whether vaccinated people could still spread the coronavirus without developing symptoms. That remains a possibility. We know that people who are naturally infected with the coronavirus can spread it without experiencing a cough or other symptoms. Researchers will study this question intensively when the vaccines are introduced. In the meantime, self-vaccinated people need to think of themselves as potential spreaders.

Will it hurt What are the side effects?

The vaccine against Pfizer and BioNTech, like other typical vaccines, is delivered as a shot in the arm. The injection is no different from the ones you received before. Tens of thousands of people have already received the vaccines, and none of them have reported serious health problems. However, some of them have experienced short-lived symptoms, including pain and flu-like symptoms that usually last a day. It is possible that people will have to plan to take a day off or go to school after the second shot. While these experiences are not pleasant, they are a good sign: they are the result of your own immune system’s encounter with the vaccine and a strong response that ensures lasting immunity.

Will mRNA vaccines change my genes?

No. Moderna and Pfizer vaccines use a genetic molecule to boost the immune system. This molecule, known as mRNA, is eventually destroyed by the body. The mRNA is packaged in an oily bubble that can fuse with a cell, allowing the molecule to slide inside. The cell uses the mRNA to make proteins from the coronavirus that can stimulate the immune system. At any given point in time, each of our cells can contain hundreds of thousands of mRNA molecules that they produce to make their own proteins. As soon as these proteins are made, our cells use special enzymes to break down the mRNA. The mRNA molecules that our cells make can only survive a few minutes. The mRNA in vaccines is engineered to withstand the cell’s enzymes a little longer, so the cells can make extra viral proteins and trigger a stronger immune response. However, the mRNA can hold for a few days at most before it is destroyed.

“When I saw the results table, my jaw dropped,” said Dr. Myron Cohen, professor of medicine at the University of North Carolina at Chapel Hill and principal researcher who helped design and conduct the study.

Although the study has ended, Dr. Daniel Skovronsky, Eli Lilly’s chief scientist, said the company would continue to rush to nursing homes on its study network if an outbreak is detected. “Everyone will get the drug,” he said.

Experts who did not take part in the study were delighted, but emphasized that they had not yet seen complete data. “I only see positive results here,” said Dr. Ofer Levy, director of the Precision Vaccination Program at Boston Children’s Hospital. “That’s a win.”

Dr. Kathleen Neuzil, director of the Center for Vaccine Development and Global Health at the University of Maryland Medical School, was also encouraged.

“The mortality effect is remarkable,” she said, adding that the drug should be used more widely to prevent and treat Covid-19, “especially in populations such as nursing home residents who have high mortality rates and may not respond optimally to vaccines . ” ”

Vaccines also protect people from contracting the virus, of course, and nursing home staff and residents were among the first group to be prioritized for the shots. But supplies are inadequate, and many nursing home workers who fear the vaccines have refused to get them.

And after vaccination, it can take six weeks for the body to produce enough antibodies for maximum protection, said Dr. Srilatha Edupuganti, vaccine researcher at Emory University in Atlanta and study researcher.

Treatment with monoclonal antibodies could provide almost equivalent protection immediately, although it does not last as long as the protection offered by a vaccine.

Eli Lilly plans to reach out to the FDA for an emergency clearance to use the drug to help prevent infection in frail elderly populations, especially in nursing homes or long-term care facilities, said Dr. Skovronsky.

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Business

Walmart will check grocery deliveries to clients’ properties

The Walmart + home screen on a laptop placed in the Brooklyn borough in New York, United States on Wednesday, November 18, 2020.

Gabby Jones | Bloomberg | Getty Images

Walmart is already bringing groceries to customers’ doors and putting them straight in the fridge in some cities. The company announced Tuesday that it will soon be testing another hands-on approach: deliveries to a smart cooler on customer porches or near their front door.

Starting earlier this spring, the big box dealer announced that it would be launching a pilot in its hometown of Bentonville, Arkansas. The participating customers receive a temperature-controlled smart cooler called HomeValet. The cooler is placed outside of the house so that safe and contactless food deliveries are possible around the clock.

“The prospect for this technology is fascinating for both customers and Walmart’s last mile delivery efforts,” said Tom Ward, senior vice president of customer products for Walmart US, in a post on the company’s website. “Customers don’t have to schedule their day to have their groceries delivered. Walmart has the ability to deliver items 24 hours a day, seven days a week.”

However, he said the retailer has no plans for 24/7 deliveries.

Walmart is testing the delivery of groceries to a HomeValet, a smart cooler that is placed outside of customers’ homes.

Walmart is the largest grocer in the United States and has made free unlimited grocery deliveries a key benefit of its new subscription-based service, Walmart +. The service started in September costs $ 98 per year or $ 12.95 per month compared to Amazon Prime which costs $ 119 per year or $ 12.99 per month. It includes other benefits such as: B. Fuel discounts and access to a smartphone app that allows buyers to skip the checkout.

The retail giant launched its grocery delivery service in 2018. During the Covid-19 pandemic, Walmart and other retailers have noticed that online grocery shopping is becoming increasingly popular. Customers are looking for convenient and contactless ways to store their pantries and refrigerators, from home deliveries to services like Instacart to roadside pickup outside of a retail store.

Even before the global health crisis, Walmart was experimenting with new food delivery options. In 2019, a membership program called InHome Grocery Delivery was launched in select cities, which brings fresh fruit, meat and other groceries straight to customers’ fridges for $ 19.95 per month. It requires additional security measures, including a smart door lock kit or smart garage door kit in buyers’ homes, as well as a background check and additional training for employees.

The service continues to operate in select cities: Pittsburgh, Kansas City, Vero Beach, Florida and West Palm Beach, Florida. During the pandemic, the company changed its approach to accommodate local restrictions, a company spokeswoman said: It only delivers in the Pittsburgh kitchen. In the other cities, objects are placed directly in the door of houses or in garages.

With the new HomeValet pilot, food is left in rectangular coolers developed by a start-up. You have three zones in which food can be kept at different temperatures – frozen, refrigerated or kept at room temperature like in a pantry. To make a delivery, a Walmart employee can lock and unlock the Smart Cooler with a device.

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The houses of Mitch McConnell and Nancy Pelosi had been reportedly vandalized.

It has been reported that the homes of political opponents and the two most powerful members of Congress, Mitch McConnell and Nancy Pelosi, have been destroyed as their stalemate continues over a stimulus package criticized by left and right as inadequate – including President Trump.

In a statement on Saturday, McConnell, a Kentucky Republican and Senate majority leader, lamented what he called a “radical tantrum” that came from a “toxic playbook.” The Louisville broadcaster WDRB-TV reported that the Senator’s house was marked with red and white spray paint overnight. Photos show the letter on the front of Mr. McConnell’s house, including a message saying “Weres my money” on the front door. The Louisville Metro Police Department did not immediately respond to a request for comment on Saturday.

“I’ve spent my career fighting for the first change and advocating peaceful protest,” McConnell said in the statement. “I appreciate every Kentuckian who has participated in the democratic process, whether they agree with me or not. That is different. Vandalism and fear politics have no place in our society. “

At around 2 a.m. on Friday, San Francisco police responded to a report of vandalism in a house in Pacific Heights. Graffiti had been sprayed on the garage door and “a pig’s head” was left on the sidewalk in front of the house, a police spokesman said. The San Francisco Chronicle reported that the house belonged to Ms. Pelosi, a Democrat who serves as the house’s spokeswoman.

Police did not answer any other questions, including whether the pig’s head discovered on the property was real or fake. The Speaker’s Office did not respond to a request for comment on Saturday.

President Trump signed a bill last Sunday that included an incentive of $ 900 billion but called for payments to individuals to be increased from $ 600 to $ 2,000. Ms. Pelosi rallied support for the postponement and the House voted on Monday to increase payments. Mr. McConnell blocked efforts the next day.

Mr McConnell said Tuesday that the Senate would “initiate a process” to consider larger payments along with Mr Trump’s other demands, including investigations into his unfounded allegations of election fraud in the 2020 election and the repeal of certain legal protections for Technology giants like Facebook, Google and Twitter.