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Britain Authorizes Covid-19 Vaccine From Oxford and AstraZeneca

These setbacks have not dampened the UK craze for the country’s leading homegrown vaccine. According to analysts, this could improve Prime Minister Boris Johnson’s tenure if rolled out quickly.

The UK has made AstraZeneca the linchpin of its vaccination strategy by ordering 100 million doses, 40 million of which should be available by March. The UK has vaccinated hundreds of thousands of people since the Pfizer vaccine was approved on December 2nd. However, the country has struggled to manage it beyond hospitals and doctor’s offices, and some of its highest priority recipients, like nursing home residents, are still at risk.

A small number of volunteers in the UK clinical trial received their first dose at half strength due to a measurement problem. Oxford had hired an outside manufacturer to manufacture the vaccine for the trial. When the researchers received a sample of the vaccine, they found that its strength was twice what the manufacturer had found using a different measuring technique. Unsure of which measurement to trust, the researchers decided to cut the dose in half to make sure the volunteers didn’t get double the intended dose. The Oxford researchers later confirmed their reading was too high and switched back to the originally planned dose for the second shot.

In the smaller group of 2,741 people who received the first half-strength dose or a meningococcal vaccine as a control, the vaccine was found to be 90 percent effective. However, none of these participants were over 55 years of age, making it difficult to know if these results would apply to the elderly.

Scientists at AstraZeneca and Oxford have said they don’t know why the half-strength starting dose was so much more effective. However, they have expressed confidence in their results, particularly in finding that no one who received the vaccine in the clinical trials has developed severe Covid-19 or has been hospitalized.

“We think we’ve figured out the formula for success and figured out how to get the effectiveness that everyone else has after two doses,” Pascal Soriot, managing director of AstraZeneca, told The Times of London in an interview published on Saturday. The company has not released any evidence of efficacy rates as high as Pfizer or Moderna. “I can’t tell you more because we will eventually publish,” Soriot told the Times.

The Oxford scientists published interim results from clinical trials of the vaccine in The Lancet earlier this month. The upcoming final results of these studies are not expected to differ significantly from the interim data, as is typical in clinical research.

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World News

A congressman-elect from Louisiana died from Covid-19 problems.

Luke Letlow, a Republican who was elected to the House of Representatives this month to represent Louisiana’s Fifth Congressional District, died Tuesday night of complications from Covid-19, a spokesman said. He was 41 years old.

Mr. Letlow was due to take office on Sunday. His death was confirmed by several politicians, including Louisiana representative Garret Graves, who said in a Facebook post that the death of his friend and “former employee” was “a great loss to Louisiana and America.” Mr Letlow died at the Ochsner LSU Health Hospital in Shreveport, La., Said spokesman Andrew Bautsch.

Mr Letlow said on December 18 that he was isolating at home after testing positive for the coronavirus. He was later hospitalized in Monroe, La., Before being rushed to the Shreveport hospital, Mr Bautsch said on Dec. 23. Mr Letlow was given the antiviral drug remdesivir and steroids to treat his infection, Mr Bautsch said.

On December 21, when he was hospitalized in Monroe, Mr Letlow urged people who had recovered from Covid-19 to donate their plasma. “Your plasma is especially needed by those who suffer,” he wrote in a tweet. “I cannot stress this enough. Please remember to save lives by going out and donating at your local blood bank. ”

Dr. GE Ghali, a doctor at Shreveport Hospital, told The Advocate in Baton Rouge, La that he had no underlying medical conditions that would have increased his chances of dying from Covid-19.

Mr. Letlow was elected to replace Rep. Ralph Abraham, whom Mr. Letlow had appointed as chief of staff, in a runoff earlier this month against another Republican.

Mr. Letlow is survived by his wife Julia and their two children Jeremiah and Jacqueline.

Spokeswoman Nancy Pelosi said in a statement: “Tonight the United States House of Representatives is sadly mourning the death of Congressman-elect Luke Letlow.

“Congressman-elect Letlow was a ninth generation Louisian who fought passionately for his point of view and dedicated his life to public service,” she said.

Kevin McCarthy, the House minority leader, said: “Our hearts break tonight as we process the news of the death of Congressman-elect Luke Letlow.”

Louisiana Governor John Bel Edwards said Tuesday evening that Covid-19 had “taken Congressman-elect Letlow from us far too early”. Mr. Edwards, a Democrat, said he had ordered flags to be hoisted halfway on the day of Mr. Letlow’s funeral.

Representative Mike Johnson, a Republican representing the state’s fourth congressional district, made a statement on behalf of the state’s six-member Congressional delegation: “We are devastated to hear of Luke Letlow’s death. Luke had such a positive mind and he had an incredibly bright future ahead of him. He looked forward to serving the people of Louisiana in Congress, and we were pleased to welcome him to our delegation where he was ready to make an even greater impact on our state and nation. “

Bobby Jindal, the former Louisiana governor for whom Mr. Letlow had previously worked when Mr. Jindal was a Congressional candidate, agent and governor, said the congressman-elect had “spoken in recent days about his excitement about being able to serve him “Circle.

“I first met Luke when he was a student and spent countless hours with him in his truck driving the back streets of Louisiana,” said Jindal. “His passion for service has been constant throughout his life.”

Ballotopedia says Mr. Letlow is the first federal elected official to die of Covid. The first member of the federal government to die from it was a judge.

Other elected officials to die from Covid include multiple lawmakers: a Republican Senator from Minnesota, New Hampshire’s new Republican House Speaker, and in North Dakota, David Dean Andahl, a Republican named “Dakota Dave” was posthumously elected to the House after he died from the virus.

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World News

Gross sales plummeted 80%, lowest haul in many years attributable to Covid-19

A Cinemark employee serves popcorn to a customer at a concession booth in Cinemark’s Century 16 at the South Point Hotel & Casino on August 14, 2020 in Las Vegas, Nevada.

Ethan Miller | Getty Images News | Getty Images

Just days before the end of the year, the effects of the coronavirus pandemic on the film industry in 2020 are clear and devastating.

According to data from Comscore, ticket sales fell 80% to $ 2.28 billion, a far cry from the second-best box office ever of $ 11.4 billion in 2019.

“To say this has been a challenging year for cinemas is an understatement,” said Paul Dergarabedian, senior media analyst at Comscore.

The year got off to a strong start: the industry raised more than $ 900 million in January, an increase of 10% over the same month last year. Much of its success was thanks to films like “Jumanji: The Next Level” and “Star Wars: The Rise of Skywalker,” which released in December 2019 and are still in theaters in January.

Ticket sales in February were over $ 651 million, up 4% year over year.

However, in March the film industry entered a period of forced hibernation when the US was locked down to contain the coronavirus pandemic.

In March 2019, the domestic box office achieved sales of 967 million US dollars thanks to blockbuster titles such as “Captain Marvel”, “Us” and “How to Train Your Dragon: The Hidden World”. With theaters suddenly closing, the box office dropped 73% to just $ 258 million in March 2020.

Even after the cinemas reopened, the largest chains remained closed until the end of August. As a result, the domestic box office has not seen more than $ 100 million in revenue in any month since March.

“The full year North American cash register numbers will obviously be a fraction of the pre-pandemic market, but the fact that it had over $ 2 billion in sales in 2020 is certainly impressive,” Dergarabedian said.

Ticket sales of nearly $ 2.3 billion in 2020 is an estimate and could change slightly before January 1. However, analysts do not expect this number to fluctuate much as less than 40% of domestic and international cinemas are open to the public which are capable of operating must do so with limited capacity. Not to mention that there are no more weekends in the year. This is the most popular time for moviegoers to go to the theater.

Assuming this number is correct, it will be the lowest number the domestic box office has collected in nearly 40 years, according to Comscore. According to Dergarabedian, it wasn’t until the early 1980s that cash tracking became coherent, making it difficult to trace the data any further.

On the way into 2021, analysts and cinema operators are more optimistic about the box office. While there won’t be any major movie releases through March, the recent opening of Wonder Woman 1984 in the US and Canada is building confidence in an industry-wide recovery.

“We are cautiously optimistic as long as needles go into our arms,” ​​said a cinema operator with locations in the southern United States about the introduction of vaccines in the country.

The hope for these companies is that enough people will be vaccinated by mid-2021 so that the cinemas will be fully occupied again and moviegoers will feel good again when they return to big blockbusters.

The list of films is especially robust considering how many films have been postponed as of 2020. These include Marvel’s “Black Widow”, the ninth “Fast and Furious” film, “Jungle Cruise”, a new “Minions” film and the James Bond film “No Time to Die.”

“Wonder Woman 1984 showed that the power and excitement of cinema still exist amid a pandemic, and that’s at least some good news in a year that the industry would like to take a back seat,” Dergarabedian said .

Disclosure: Comcast is the parent company of NBCUniversal and CNBC. NBCUniversal is the studio behind the “Fast and Furious” films and has international distribution rights for “No Time to Die”.

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World News

Australia’s economic system after Covid-19 pandemic

The national flags of Australia and China are displayed in front of a portrait of Mao Zedong overlooking Tiananmen Square.

Frederic J. Brown | AFP via Getty Images

Australia’s economy has been hit hard by escalating trade tensions with China – and it is possible that even after the pandemic ends, growth “will never return to pre-virus levels,” according to research firm Capital Economics.

China is by far Australia’s largest trading partner, accounting for 39.4% of goods exports and 17.6% of services exports between 2019 and 2020.

But Beijing has been targeting a growing list of imported products from Down Under for months – tariffs on wine and barley and suspension of beef imports.

Australia’s gross domestic product (GDP) could continue to shrink if Beijing continues to pile tariffs on more Australian imports, its chief economist Marcel Thieliant said in a note last week.

Goods and services already “in the line of fire” are worth almost a quarter of Australia’s exports to China – 1.8% of economic output, according to the research company.

But it can’t end there.

“That number could climb to around 2.8% of GDP if China targets other products for which it does not depend heavily on Australian imports,” Thieliant said.

While Australia should be able to reroute some shipments to other countries, the escalating trade war is another reason why the Australian economy will never return to its pre-virus path, even after controlling the pandemic.

Marcel Thieliant

Economist, capital economy

Canberra-Beijing bilateral relations deteriorated earlier this year after Australia backed a growing demand for an international investigation into China’s handling of the coronavirus pandemic.

Other restrictions from Beijing could come, including exports of gold, aluminum oxide – a type of material for industrial use – and “a wide variety of smaller goods,” the report said.

“While Australia should be able to reroute some shipments to other countries, the escalating trade war is another reason the Australian economy will never return to its pre-virus path even after the pandemic is controlled,” Thieliant said.

Overall, the country’s gross domestic product could lag its pre-virus level by about 1.5 percentage points by the end of 2022 – and additional trade restrictions from China could exacerbate this shortage, Capital Economics said.

The pain could be alleviated, however, as “Australia may find other destinations for its exports,” said the economist.

A ray of hope for Australia

Australia is the world’s largest iron ore producer, another commodity that has been in the spotlight as tensions between Australia and China increased.

But there is a ray of hope for Australia: iron ore exports would likely continue to be spared as Australia supplies half of China’s needs.

China imports 60% of its iron ore from Australia and is heavily dependent on the commodity from which steel is made.

Analysts say the lack of available alternatives could be the reason iron ore has so far been spared the tariff war.

Iron ore prices recently rose as demand from China increased and were further fueled by dwindling supply and disruption caused by storms in Australia.

“We still believe that iron ore exports will be spared … Without Australia, China would not be able to meet all of its current needs,” Thieliant wrote.

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Health

What to Know of Covid-19 Antibody Medication: Price, Availability and Extra

Two new antibody treatments have shown promise in keeping high-risk Covid-19 patients out of the hospital.

Although President Trump, who received Regeneron treatment in October and lauded it as a “cure,” received a boost in advertising, the drugs have not been widely distributed since they were approved for emergency use by the Food and Drug Administration last month.

Now federal and state health authorities are calling on patients and doctors to seek treatments.

Here’s what you need to know.

The two treatments by Eli Lilly and Regeneron are the first drugs specifically designed for Covid-19 and approved by the FDA. They are made from artificially synthesized copies of the antibodies that humans naturally produce when their immune systems fight off an infection. Eli Lilly’s drug consists of an antibody. Regeneron’s is a cocktail of two.

Early data showed that it can prevent hospitalization in people at high risk of serious complications from the disease. Clinical studies continue. The treatments are believed to help turn the virus off shortly after infection.

Treatments can be given to anyone who tests positive for the coronavirus, is at high risk of developing a severe form of the disease, and occurs within 10 days of symptoms first appearing.

This includes people who are at least 65 years old and those who are obese or have diseases such as diabetes.

The treatments are not approved for people who have already been hospitalized or need oxygen, as studies in these groups have not shown the drugs to work well.

Under agreements each company has made with the federal government, the doses are free, although some patients may have to pay for the administration of the drug, which must be infused by a healthcare provider, depending on insurance coverage.

Monoclonal antibody treatments are difficult and time consuming to manufacture, which has limited the number of doses made by drug manufacturers.

The federal government has bought 950,000 cans from Eli Lilly and 300,000 cans from Regeneron. Pharmaceutical companies have already dispensed hundreds of thousands of these doses, with the rest expected in late January.

Nobody knows, but many of the cans that have been distributed so far have remained unused and are sitting in hospital refrigerators.

While the federal government has nearly 532,000 doses of the two drugs available and nearly 291,000 doses have been shipped, neither the government nor the drug companies have complete data on how many of these doses have been given to patients.

The subset of hospitals that report data to the government on the number of doses administered has, on average, used only 20 percent of their supply, according to the Department of Health and Human Services.

The drugs are used unevenly across the country. Some hospitals cannot get enough doses. Others haven’t even used much of what they got so far.

Several factors have contributed to the underutilization: Hospitals are overwhelmed by the virus flood and are focusing on the first vaccines. And they need to be housed in their crowded facilities where the treatments can be infused over a period of hours without spreading the virus to others.

Some patients have been reluctant to engage in treatments, be it because they are unwilling to go to a clinic while feeling sick, lack of transportation, or because they perceive the drugs as connected people only for patients who are felt to be good. And the scarcity of treatments adds to their underuse as some hospitals withhold supplies for fear of leakage.

There is no single hotline or website that patients can use to find a provider who offers the treatments.

Many health systems have put in place ways to identify and contact eligible patients who have tested positive for the coronavirus at test sites or in doctor’s offices. However, these referral systems vary from municipality to municipality.

Eli Lilly’s support line for treatment is 1-855-545-5921. A Regeneron spokeswoman recommended that patients or doctors contact the state health department.

Dr. Daniel Skovronsky, Eli Lilly’s chief scientist, said he advises friends and family members to call the company’s hotline. “If you are persistent and you qualify, you will get it,” he said.

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Health

Who Ought to Get the Covid-19 Vaccine Subsequent? A Debate

Bazelon: We need them!

Ezike: Law. However, I think there is a possible problem with the long-term care population. Many of these people may still die for other reasons, but then the conclusion might be, “Grandma got the vaccine and died in the next week.” These are elderly people with comorbidities and their death coincides with time after vaccination but is not caused by the vaccine. However, I think this is going to be confusing for a lot of people. If health care workers get vaccinated and survive, people can gain the confidence to say, “OK, I’m ready now. I stand in line. “I think there will be this big push in the end when people say,” So far, so good. “

Gonsalves: If you follow Peter’s age-based utilitarianism, we should prioritize immunizing the people of the global south. Most of the young people on this planet live there.

Singer: I totally agree. Getting vaccines to the global south should be a very high priority.

Gonsalves: However, for now, most vaccinations are given in Europe, Australia, New Zealand, the UK, the US and Canada. The People’s Vaccine Alliance, which includes Amnesty International and Oxfam, just released a report that says that in 70 lower-income countries, only 1 in 10 people will have access to the vaccine by 2021. We are setting up some sort of medical apartheid in the next few months and even a few years where the virus will be under control in the US, Europe and some other places, but if you come from another country with no proof of immunity and trying to get a student visa to the US, good luck.

Ezike: Think more globally when I think of Nigeria, my father’s birthplace – access to vaccines, access to tests, all of that is limited there. We are not seeing a significant number of deaths in Nigeria and that is a godsend. But if broadcast were widespread, considering how many Nigerians travel overseas, there would be serious repercussions across national borders.

Bazelon: The rich countries seem to be planning to hoard vaccines. The European Union has ordered enough to immunize its residents twice. The UK and United States could each vaccinate four times if the supplies they set up are delivered, and Canada six times, according to a New York Times analysis of data on vaccination contracts. The World Health Organization and others have led an international initiative called Covax, which is providing a billion doses to less wealthy countries. But that’s not enough for a fair distribution.

Gonsalves: Here we go again, right? I mean, I am an epidemiologist. I am also an AIDS activist. And in 1996 a highly active antiretroviral therapy came out, and where did it go? It went to the industrialized north. And within a few years everyone around the world has been asking for it.

Mukherjee: Companies in India manufacture hundreds of millions of doses of Covid vaccines. China and Russia also have vaccines. However, we don’t know if any of these vaccines were tested with the same accuracy as the Pfizer and Moderna vaccines. For me, this is the most unfortunate thing about vaccine testing that has happened by far. The only data we have on the Chinese vaccine is from the United Arab Emirates and Bahrain, and we don’t know its effectiveness. They say it’s 86 percent; We don’t know real numbers. The Russian vaccine also released very little information. Then there is the AstraZeneca vaccine which has had data problems.

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Health

U.S. to Require Adverse Covid-19 Check for All Vacationers From U.Okay.

The United States will require all passengers arriving from the UK to test negative for the coronavirus within 72 hours of their departure, the Centers for Disease Control and Prevention said Thursday.

The move comes as a new highly transmissible variant of the virus, which first appeared in the UK, has led countries to seal their borders to travelers from there.

The new rule, which goes into effect on Monday, applies to both Americans and foreign nationals and requires passengers to provide evidence of a negative result in a genetic test known as a PCR or antigen test.

“This additional test requirement will strengthen our protection of the American public to improve their health and safety and to ensure responsible international travel,” the CDC said in a statement.

Passengers are required to provide the airline with “written documentation of their laboratory test result (in print or electronic form),” the CDC said, adding, “If a passenger does not take a test, the airline must refuse to board the passenger.”

The new rules were a reversal for the Trump administration, which initially told American airliners that the government would not require testing for travelers from the UK.

United Airlines, Virgin Atlantic and Delta Air Lines had already announced similar guidelines requiring all passengers on their flights between the UK and the United States to provide evidence of a negative test result within 72 hours of departure. British Airways also requested negative test results for passengers arriving in New York.

Several of the airlines announced their policies after New York Governor Andrew M. Cuomo requested that passengers coming from London to John F. Kennedy International Airport must document a negative test result.

“We cannot allow history to repeat itself with this new variant,” Mr Cuomo wrote on Twitter.

Also on Thursday, New Jersey Governor Phil Murphy said that passengers arriving at Newark Airport would require negative tests within 72 hours of departure to enter.

American travel requirements are less draconian than those of other countries in Europe and Asia, which excluded all travelers from the UK after the advent of the new coronavirus variant. Experts are skeptical that travel bans can stop the spread of the variant. Dr. Anthony S. Fauci, the leading U.S. infectious disease expert, said there was a good chance the variant was already in the country.

“I don’t think such a draconian approach is necessary,” he said of a travel ban for PBS NewsHour. “I think we should give serious thought to the possibility of requiring people to be tested before they come here from the UK.”

A recent study by British scientists found no evidence that the variant was more lethal than others. However, the researchers estimated that it was 56 percent more contagious. The country also announced a travel ban from South Africa after Health Secretary Matt Hancock said two people were discovered with another variant that had surfaced in the African country. Another variant has also appeared in Nigeria.

The UK authorities this week put much of England under renewed restrictions on travel and socializing, warning that schools and universities may have to close soon.

Vivian Wang contributed to the coverage.

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Health

How Midwives Have Stepped in in Mexico as Covid-19 Overshadows Childbirth

Rafaela López Juárez was determined that if she ever had another child, she would try to give birth at home with a trusted midwife who is surrounded by family. Her first hospital birth had been a traumatic ordeal, and her perspective changed drastically afterwards when she trained as a professional midwife.

“What women want is a birthing experience that is centered on respect and dignity,” she said. She believes low risk births should take place outside of hospitals, at home, or in dedicated birthing centers where women can choose how to give birth.

In late February, Ms. López and her family awaited the arrival of their second child at their home in Xalapa, Mexico as they followed the threatening news of the coronavirus pandemic invading. She gave birth to Joshua, a healthy boy, on February 28, the day Mexico confirmed its first case of Covid-19. Ms. López wondered how the pandemic would affect her job.

About 96 percent of births in Mexico occur in hospitals, which are often overcrowded and poorly equipped. Many women describe being treated badly or disrespectfully. The pandemic outbreak raised concerns that pregnant women in hospitals could be exposed to the virus, and women’s health advocates in Mexico expressed hope around the world that the crisis could become a catalyst for lasting changes to the system.

A national movement has made determined but uneven progress in integrating midwives into Mexico’s public health system. Some authorities argue that well-trained midwives would be of great value, particularly in rural areas, but also in small non-surgical clinics across the country. However, until now there has not been enough political will to provide the regulation, infrastructure and budgets necessary to employ enough midwives to make a significant difference.

In the first few months of the pandemic, there was isolated evidence that midwives were gaining importance in the country. Midwives across Mexico have been inundated with requests for home births. The government encouraged state agencies to set up alternative health centers that focus exclusively on childbirth and could be staffed with nurses and midwives.

As the outbreaks of Covid spread, health officials across the country saw a sharp drop in prenatal consultations and hospital births. At Acapulco General Hospital in the Mexican state of Guerrero, Dr. Juan Carlos Luna, the director of maternal health, found a 50 percent decrease in births. Since skeleton workers sometimes worked in double shifts, doctors and nurses were enforced under difficult conditions. “Almost everyone on my team has tested positive for the virus at some point,” said Dr. Luna.

In the intensive care unit Covid-19 in Acapulco General, doctors treated María de Jesús Maroquín Hernández. She had developed breathing problems in the 36th week of pregnancy and asked her family to drive her to the hospital for four hours. Doctors isolated Ms. Maroquín while her family waited outside as funeral directors carried away the dead Covid patients, worrying that she would be next. She was released five days later and soon gave birth via a caesarean section in a hospital near her home. She and her husband decided to name their little girl Milagro – miracle.

In Mexico’s indigenous communities, women have long relied on traditional midwives, who are becoming even more important today. In Guerrero, some women have given birth to midwives in special indigenous women’s centers called CAMIs (Casas de la Mujer Indígena o Afromexicana), where women can also seek help with domestic violence, which according to CAMI staff has increased. However, austerity measures in connection with the pandemic have deprived the centers of essential funds from the federal government.

Other women have chosen to quarantine themselves in their communities for help from midwives like Isabel Vicario Natividad, 57, who continues to work despite their own health conditions making them vulnerable to the virus.

As Covid-19 cases in Guerrero increased, state health officials reached out to women and midwives in remote areas with potentially high maternal and child mortality rates.

Updated

Apr. 24, 2020, 8:33 am ET

“If the women are too scared to come to our hospitals, we should look for them where they are,” said Dr. Rodolfo Orozco, director of reproductive health in Guerrero. With the support of a handful of international organizations, his team recently started visiting traditional midwives for workshops and handing out personal protective equipment.

In the capital Chilpancingo, many women discovered the Alameda Midwifery Center, which opened in December 2017. In the early stages of the pandemic, the center’s birth rate doubled. In October, Anayeli Rojas Esteban, 27, traveled to the center for two hours after her local hospital was unable to admit her. She was pleasantly surprised to find a place with midwives who actually allowed her to give birth in the company of her husband, José Luis Morales.

“We’re especially grateful that they weren’t cut like they were when they were first born in the hospital,” said Morales, referring to an episiotomy, a surgical procedure that is routine in hospital settings but is increasingly viewed as unnecessary.

While Mexico’s state health authorities battled to contain the virus, the situation in the country’s capital highlighted the dangers and frustrations women felt.

In the spring, health officials in Iztapalapa, Mexico City’s most densely populated neighborhood, got mixed up as the area became the center of the country’s coronavirus outbreak. The city government converted several large public hospitals in Iztapalapa into treatment facilities for Covid-19 patients, leaving thousands of pregnant women desperate for alternatives. According to Marisol del Campo Martínez, the clinic’s manager, many have sought refuge in maternity clinics such as Cimigen, where the number of births doubled and the number of prenatal visits quadrupled.

Other expectant mothers joined the growing number of women seeking a home delivery experience for safety reasons and to avoid potentially unnecessary cesarean sections. In Mexico, around 50 percent of babies are delivered by caesarean section, and pregnant women are pressured by their peers, family members and doctors to perform the procedure.

In July, 30-year-old Nayeli Balderas, who lived near Iztapalapa, reached out to Guadalupe Hernández Ramírez, an experienced perinatal nurse and president of the Association of Professional Midwives in Mexico. “When I started doing research on humanized childbirth, breastfeeding, etc., a whole new world opened up to me,” said Ms. Balderas. “But when we told our gynecologist about our plan, her whole face changed and she tried to scare us.” Undaunted, Mrs. Balderas proceeded with her birth plan.

Their work was long and increasingly difficult. After 12 hours, Ms. Balderas and her husband discussed with Ms. Hernández and decided to activate their plan B. At 3 a.m., they rushed to Dr. Fernando Jiménez, a gynecologist and colleague of Ms. Hernández, where it was decided that a caesarean section was needed.

Across Mexico City, 26-year-old Maira Itzel Reyes Ferrer had also screened home births in September and found María Del Pilar Grajeda Mejía, a 92-year-old certified traditional midwife who works with her granddaughter Elva Carolina Díaz Ruiz, 37 , trained obstetrician. They guided Ms. Reyes through a successful home birth.

“My family admitted that sometimes they were concerned during childbirth,” Ms. Reyes said. “But in the end they loved the experience so much that my sister is now taking a midwifery course. She has already paid and started! “

At the start of winter, Mexico faces a devastating second wave of the coronavirus. The hospitals in Mexico City are quickly running out of space. The much-discussed birth centers run by state midwives have not yet come into being, and medical staff in renowned hospitals such as the National Institute of Perinatology or INPer work around the clock.

At the beginning of the pandemic, INPer employees found that around a quarter of all women admitted to the hospital tested positive for the coronavirus. The administrators set up a separate Covid-19 ward, and Dr. Isabel Villegas Mota, head of the hospital’s epidemiology and infectious diseases department, managed to ensure adequate personal protective equipment for staff. Not all front-line workers in Mexico were so lucky. The Covid-19 death rate for medical workers in Mexico is among the highest in the world.

When Grecia Denise Espinosa learned that she was pregnant with twins, she planned to give birth in a well-known private clinic. But she was shocked at the high cost and decided to see doctors at INPer instead. To her surprise, when she got to the hospital in November, she tested positive for the virus and was sent to the Covid-19 department, where doctors performed a c-section.

Maternal health advocates have long said that Mexico’s model of obstetrics needs to change to focus on women. If ever there was a moment for health officials to dedicate themselves fully to the midwife, now is the time to argue that the thousands of midwives across the country could help ease the pressure on an overburdened and often suspicious healthcare system and provide quality care to women.

“The model we have in Mexico is an outdated model,” said Dr. David Meléndez, technical director of the Safe Motherhood Committee Mexico, a non-profit organization. “It’s a model where we all lose. The women lose, lose the land, and lose the health system and medical staff. We are stuck in the middle of a global pandemic with a bad model at the worst possible moment. “

picture

Janet Jarman is a Mexico-based photojournalist and documentary filmmaker and director of the documentary “Birth Wars”. It is represented by Redux Pictures.

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Health

Covid-19 vaccine shortfalls attributable to confusion over FDA necessities

Employees move boxes of Pfizer-BioNTech Covid-19 vaccine as they prepare for shipment at Pfizer Global Supply’s Kalamazoo manufacturing facility in Kalamazoo, Michigan on December 13, 2020.

Morry Gash | AFP | Getty Images

Officials at Operation Warp Speed, the U.S. government’s program to distribute Covid-19 vaccines to Americans, had to cut doses for several states due to confusion over the U.S. Food and Drug Administration’s certificate of analysis for rounds of vaccination.

The federal government’s mistake disrupted vaccination distribution plans in at least 14 states and frustrated governors and state health officials who said they were surprised to learn of shipping shortages.

Operation Warp Speed ​​has put 2 million Pfizer vaccine doses ready for delivery next week, after the US shipped 2.9 million doses last week. Officials also plan to ship 5.9 million doses of Moderna’s vaccine this week.

Dr. Moncef Slaoui, chief advisor to Operation Warp Speed, said the agency mistakenly assumed that Pfizer’s vaccine was ready to ship when there was actually a two-day delay in which the FDA required a certificate of analysis for each batch of vaccines.

“This delay has led to differences in the plan and in the actual measures,” Slaoui said in an interview on CNN’s State of the Union on Sunday. “We’ve looked at it and optimized what we’re doing every day.”

The FDA requires a certificate of analysis for each round of Pfizer vaccines at least 48 hours prior to distribution, but does not require the certificate to be verified prior to shipment. The certificate contains quality control test results and is required when Pfizer uses an emergency approval under the FDA.

Former GlaxoSmithKline pharma executive Moncef Slaoui, who will serve as the chief advisor in the search for a vaccine against the coronavirus disease (COVID-19) pandemic, speaks while President Donald Trump during a coronavirus response event Illness in the rose garden at the White Hearts House in Washington.

Kevin Lamarque | Reuters

Operation Warp Speed’s Chief Operating Officer, General Gustave Perna, who is responsible for the logistics for shipping the vaccines, repeatedly apologized for smaller vaccine shipments on Saturday and took responsibility for the “planning error”.

“The mistake I made is not really understanding – again my responsibility – what steps are needed to make sure the vaccine is releasable,” Perna said at a press conference.

States where fewer than expected numbers occur include Washington state, New Jersey, Virginia, Idaho, Michigan, Connecticut, California, Nevada, Minnesota, Wisconsin, Vermont, Massachusetts, Iowa, and Oregon.

Washington Governor Jay Inslee said Thursday that the Centers for Disease Control and Prevention had told him that vaccine allocations for his state had been cut by 40% and that other states had similar deficits.

General Gustave Perna, Chief Operating Officer for the Department of Defense’s Warp Speed ​​Project, speaks during a White House Coronavirus Task Force press conference in the James Brady Press Room at the White House in Washington, DC on November 19, 2020.

Tasos Katopodis | Getty Images News | Getty Images

“It’s disruptive and frustrating. We need accurate, predictable numbers to plan and ensure on-site success,” wrote Inslee in a tweet. “No explanation was given.”

Pfizer spokeswoman Kim Bencker told CNBC in an email after Perna apologized that the company had millions of cans in warehouses ready to ship once the company received confirmation from Operation Warp Speed.

“We remain confident that we can dispense up to 50 million doses worldwide this year and up to 1.3 billion doses next year,” said Bencker.

U.S. Surgeon General Jerome Adams said the introduction of the vaccine will be the toughest vaccination program in history, warning that there will be inconsistencies in the number of planned doses and the doses actually allocated.

“This will be the technically and logistically most difficult vaccination project of all time,” said Adams on Sunday in an interview with CBS ‘”Face The Nation”. “We started slowly and will continue to grow. The American people should be hopeful about the vaccines, but we also need to remain vigilant.”

– CNBC’s Noah Higgins-Dunn contributed to the coverage

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Business

Why adverts might be a discount amid Covid-19

The Kansas City Chiefs celebrate with the Vince Lombardi Trophy after defeating the San Francisco 49ers 31-20 in Super Bowl LIV at Hard Rock Stadium on February 2, 2020 in Miami, Florida.

Ronald Martinez | Getty Images

There’s no better commercial on TV than the National Football League Super Bowl Sunday. Companies are using the NFL’s title game to launch new products and campaigns and raise consumer awareness.

But with the pandemic affecting NFL planning, advertisers who are not yet committed could get last-minute discounts on Super Bowl slots.

Kevin Krim, founder and CEO of advertising data company EDO, said advertisers had raised concerns about the NFL’s postponement of some regular season games when players with Covid-19 went out. They want security around the February 7th game.

“The marketers put a lot of emphasis on predictability,” Krim said in an interview with CNBC. “They don’t want things to keep changing and the NFL knows it. The playoffs are too valuable to be disturbed.”

“Nothing would be more devastating than a postponement,” added Dave Morgan of advertising data analytics company Simulmedia. The company uses its metrics to help advertisers measure the impact of national ad slots on network programming.

New York Giants wide receiver Sterling Shepard (87) caught a pass in the first half at MetLife Stadium in front of Pittsburgh Steelers strong security Terrell Edmunds (34) and linebacker Devin Bush (55).

Vincent Carchietta | USA TODAY Sports

NFL’s nightmare

The NFL’s most recent Covid-19 outbreak hit Baltimore Ravens, causing their contest three times in week 12 with the Pittsburgh Steelers postponed.

That hurt NBC. Advertising paid top dollar for the game originally scheduled for Thanksgiving – when everyone is home and enjoys watching football – but was eventually moved to the following Wednesday at 3:40 p.m. CET. Raven’s star quarterback LaMar Jackson was out due to Covid-19, which further dulled interest in the game.

Crimea estimates that advertisers have lost value for the game. His firm estimated that the NFL’s 2019 Thanksgiving night game generated $ 62.8 million for the network, and Morgan added that the 2020 competition would have been worth $ 70 million.

The Wednesday game drew 10.8 million viewers on NBC, compared to last year’s regular Thanksgiving game, which drew around 21 million viewers. When companies don’t get their negotiated audience value for the commercials, networks usually compensate for this with “make goods” – free commercials elsewhere.

Tony Ponturo, longtime sports marketing manager, said advertisers shouldn’t settle for the free commercials because “it’s an easy way for the network to pay off – with more units,” said Ponturo. “Yeah, it’s weight, but it’s not exactly the pressure you wanted it to be.”

Ponturo, the former vice president of global media sports and entertainment marketing for Anheuser-Busch, noted that advertisers want safe dates for NFL games because they too have plans for promotions. Should NFL games continue to be postponed, it will affect their marketing.

“You have to plan and put the weekly goals under pressure,” said Ponturo. “You can do promotions, you can have retail displays, you can have all sorts of things. And when games are moving, it’s not what you bought.”

“It’s a big problem,” added Morgan. “Corporations are planning to bring automobiles to market. They are planning pizza specials. You can’t postpone this for a week. You must already have your thousands of franchises out of sign and supplies. You must have trained teams, and they must. ” ahead. “

To combat more post-season postponements, the NFL hovered to keep teams in market-friendly hotels and considered a training camp model. But on Wednesday, League Commissioner Roger Goodell said the idea had been discarded.

Instead, the NFL will seek to combat further outbreaks by providing household members of players and team staff with Covid-19 tests that lead to the Super Bowl. Morgan said the training camp model could have reassured potential advertisers looking to do deals with CBS before the Super Bowl.

“The NFL needs to make sure it hits that date,” Morgan said. “I have to believe they are on top of it. They will control the environment for the players going to the Super Bowl.”

CBS ready to close a deal?

On the broadcast side, CBS may have to get creative with the remaining Super Bowl slots.

The ads are valued at $ 5 million to $ 6 million. According to Bloomberg, Fox raised more than $ 400 million last year and sold around 77 paid ads at around $ 5.6 million each. According to sources familiar with the network’s NFL pricing, CBS is charging roughly $ 5.5 million for 2021 spots.

The network has sold nearly 80% of its package, according to the Sports Business Journal, and national companies like Toyota have already secured spots. However, marketers estimated that most of the slots sold consist of pre-negotiated packages.

To keep the ad price on the remaining slots, media pundits said CBS would likely package the Super Bowl with other NFL or sports programming packages to make it attractive to companies that are still on the fence.

Ponturo said the move protects CPM (cost per thousand impressions) and CBS “can and will maintain credibility about the Super Bowl award.” [companies] was given different inventory to make all CPM work. Nobody knows what the secret sauce is to keep this unit price going, but they are all packages to some extent. “

But with Covid-19 intercepting portions of the NFL’s schedule, Krim says he isn’t “surprised that CBS didn’t sell as much of the game as Fox or NBC in the past”. He predicted that CBS could generate less than $ 600 million in revenue for the game’s commercials if the uncertainty surrounding the NFL persists.

“Nobody is going to try to close the last 20% until you’re sure,” added Morgan.

Lamar Jackson # 8 of the stiff arms of the Baltimore Ravens Juan Thornhill # 22 of the Kansas City Chiefs at M&T Bank Stadium on September 28, 2020 in Baltimore, Maryland.

Todd Olszewski | Getty Images

Morgan anticipates the ads will be sold out, but it could be up to the last few days. He said the move could also help CBS, as the network could pack in too much content to secure Super Bowl deals.

“They won’t negotiate until the days before,” said Morgan. “With alternative pricing models, money is always available – available the day before [the Super Bowl]literally. “

Crimea said the 2021 Super Bowl ads could also be influenced by movie studios holding back movies. Studios tend to be last minute buyers who wait to know the movies are complete. As theaters are either closed or could close again due to the recent surge in Covid-19, this may have an impact on buyers.

Crimea said non-tied businesses should “stay close” as discounts may be available too late.

“At the right price, especially if you can get a discount, you will get great results with an NFL ad,” said Krim. “The only thing you know about the NFL is the most exciting thing on TV, followed by the NBA.”