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Health

Specialists Urge Air High quality Requirements as Safeguard Towards Coronavirus

Clean water in 1842, food safety in 1906, ban on leaded paints in 1971. These sweeping public health reforms have changed not only our environment but also expectations of what governments can do.

According to a group of 39 scientists, now is the time to do the same for indoor air quality. In a sort of manifesto published Thursday in Science magazine, researchers called for a “paradigm shift” in the way citizens and government officials think about the quality of the air we breathe indoors.

The timing of the scientists’ call to action coincides with the large-scale reopening of the country as coronavirus cases drop sharply: Americans are about to return to offices, schools, restaurants, and theaters – exactly the kind of crowded indoor spaces that the coronavirus is thought to thrive.

There is little doubt that the coronavirus can linger in the air indoors and soar well beyond the recommended six-foot distance, the experts said. The accumulated research places policymakers and civil engineers under an obligation to provide clean air in public buildings and to minimize the risk of respiratory infections.

“We expect clean water from the taps,” said Lidia Morawska, group leader and aerosol physicist at the Queensland University of Technology in Australia. “We expect clean and safe food when we buy it in the supermarket. We should also expect clean air in our buildings and in all common spaces. “

Fulfilling the group’s recommendations would require new workplace air quality standards, but the scientists claimed that remedial action needn’t be onerous. Indoor air quality can be improved with a few simple fixes: adding filters to existing ventilation systems, using portable air purifiers and ultraviolet lights – or just opening windows where possible.

Dr. Morawska led a group of 239 scientists who last year called on the World Health Organization to recognize that the coronavirus can spread in tiny droplets, or aerosols, that drift through the air. WHO had insisted that the virus only spread in larger, heavier droplets and by touching contaminated surfaces, which went against their own 2014 rule of assuming that all new viruses are in the air.

The WHO admitted on July 9th that aerosol transmission of the virus could be responsible for “Covid-19 outbreaks that have been reported in some closed settings, such as in a public house. For example, in restaurants, night clubs, places of worship or workplaces where people may shout, speak or sing ”, but only at a short distance.

The pressure to take measures to prevent airborne spread has increased recently. In February, more than a dozen experts requested the Biden administration to update workplace standards for high-risk environments such as meat packers and prisons where Covid outbreaks were widespread.

Last month, a separate group of scientists detailed 10 lines of evidence demonstrating the importance of indoor air transmission.

On April 30, the WHO pushed forward and allowed aerosols to “float in the air or move more than 1 meter (long range)” in poorly ventilated rooms. The Centers for Disease Control and Prevention, which were also slow to update their guidelines, realized last week that the virus can be breathed indoors, even if a person is more than three feet from an infected person.

“You have ended up in a much better, more scientifically feasible place,” said Linsey Marr, Virginia Tech airborne virus expert and signatory of the letter.

Updated

May 17, 2021 at 11:35 a.m. ET

“It would be helpful if they ran a public service messaging campaign to promote this change more widely,” she said, especially in parts of the world where the virus is soaring. For example, in some East Asian countries, stacked toilet systems could transport the virus between the floors of a multi-story building, she noted.

Further research is also needed to determine how the virus moves indoors. Researchers at the Department of Energy’s Pacific Northwest National Laboratory modeled the flow of aerosol-sized particles after a person in a three-room office with a central ventilation system had a five-minute coughing fit. Clean outside air and air filters reduce the flow of particles in this room, the scientists reported in April.

A rapid exchange of air – more than 12 in an hour – can move particles into connected rooms, just as second-hand smoke can pour into lower levels or nearby rooms.

“A lot more ventilation is a good thing for the source room,” said Leonard Pease, chemical engineer and lead author of the study. “But this air goes somewhere. Perhaps more ventilation is not always the solution. “

In the United States, the CDC’s license can cause the Occupational Safety and Health Agency to change its air quality regulations. Air is harder to hold and clean than food or water. However, OSHA already prescribes air quality standards for certain chemicals. The guide for Covid does not require ventilation improvement except in healthcare.

“Ventilation is really part of the approach OSHA takes to all airborne hazards,” said Peg Seminario, who served as the AFL-CIO’s director of safety and health at work from 1990 until her retirement in 2019 these approaches should apply to the air. “

In January, President Biden instructed OSHA to issue temporary emergency guidelines for Covid by March 15. OSHA missed the deadline, however: the draft is reportedly under review by the White House regulator.

In the meantime, companies can do as much or as little as they want to protect their workers. Citing concerns about the continuing shortage of protective equipment, the American Hospital Association, an industry trade group, endorsed N95 respirators for healthcare workers only during medical procedures known to produce aerosols or when in close contact with an infected person Patients have. These are the same guidelines that the WHO and CDC offered at the start of the pandemic. Face masks and plexiglass barriers would protect the rest, the association said in a March statement to the House Committee on Education and Labor.

“They are still stuck in the old paradigm, they have not accepted the fact that speaking and coughing often produce more aerosols than these so-called aerosol producing processes,” said Dr. Marr from the hospital group.

“We know plexiglass barriers don’t work,” she said and can actually increase the risk, possibly because they obstruct proper airflow in a room.

The improvements don’t have to be expensive: in-room air filters cost less than 50 cents per square foot, although a lack of supply has raised prices, said William Bahnfleth, professor of architectural engineering at Penn State University and head of the Epidemic Task Force at Ashrae ( the American Society for Heating, Cooling and Air Conditioning Engineers), which sets standards for such devices. UV light built into a building’s ventilation system can cost up to $ 1 per square foot. Those that are installed room-by-room perform better, but could cost ten times as much, he said.

If OSHA rules change, demand could lead to innovation and lower prices. There are precedents to believe that this could happen, according to David Michaels, a professor at George Washington University who served as OSHA director under President Barack Obama.

When OSHA tried to control exposure to a carcinogen called vinyl chloride, which is the building block of vinyl, the plastics industry warned about it threatening 2.1 million jobs. In fact, within a few months, companies have “actually saved money and not a single job has been lost,” recalls Dr. Michaels.

In either case, absentee workers and healthcare costs can prove more costly than ventilation system updates, the experts said. Better ventilation helps thwart not only the coronavirus but other respiratory viruses that cause influenza and colds, as well as pollutants.

Before people realized the importance of clean water, cholera and other water-borne pathogens claimed millions of lives worldwide each year.

“We live with colds and runny nose and just accept them as a way of life,” said Dr. Marr. “Maybe we don’t really have to.”

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Health

How the USA Beat the Coronavirus Variants, for Now

On December 29, a National Guard in Colorado became the first known case in the United States of a contagious new variant of the coronavirus.

The news was unsettling. The variant, named B.1.1.7, had upset Britain, began to grow in Europe, and threatened to do the same in the United States. And while scientists didn’t know it yet, other mutants began popping up across the country. These included variants that had ravaged South Africa and Brazil that appeared to bypass the immune system, as well as others that were native to California, Oregon, and New York.

This mixture of variants could not have come at a worse time. The nation was at the beginning of a spate of post-vacation cases that would dwarf any previous waves. And the spread of powerful vaccines from Moderna and Pfizer-BioNTech has been botched by chaos and misunderstandings. Scientists warned that the variants – and especially B.1.1.7 – could lead to a fourth wave and that the already strained health system could give way.

That didn’t happen. B.1.1.7 became the predominant version of the virus in the United States and now accounts for nearly three quarters of all cases. But the surge experts feared they were just a slip-up in most of the country. The nationwide total daily new cases began to decline in April and is now down more than 85 percent from horrific highs in January.

“It’s pretty humble,” said Kristian Andersen, a virologist at Scripps Research in La Jolla, California.

Dr. Andersen and other virus watchers still see variants as a potential source of problems in the coming months – especially one that has ravaged Brazil and is growing rapidly in 17 US states. But they are also taking stock of the past few months to better understand how the nation has evaded the variant threat.

Experts point to a combination of factors – masks, social distancing, and other restrictions, and possibly a seasonal decline in infections – that gave tens of millions of Americans crucial time to vaccinate. They also attribute a good dose of serendipity as B.1.1.7 is powerless against the vaccines unlike some of its competitors.

“I think we were lucky to be honest,” said Nathan Grubaugh, an epidemiologist at Yale University. “We are saved by the vaccine.”

After B.1.1.7 appeared at the end of December, new variants with combinations of disruptive mutations came to light. Scientists worried about how competition between the variants might develop.

In January, researchers in California discovered a variant with 10 mutations that was becoming more common there and drifting to other states. Laboratory experiments suggested that the variant of antibody treatment that had worked well against previous forms of the virus could be evaded, and that it was possibly more contagious as well.

In the months that followed, the United States dramatically improved its surveillance for the mutation of the variants. Last week, more than 28,800 virus genomes, nearly 10 percent of all positive test cases, were uploaded to an international online database called GISAID. This clearer picture has allowed scientists to observe how the mutants compete with each other.

The California variant proved a weak competitor, and its numbers fell sharply in February and March. It’s still common in parts of northern California, but it has virtually disappeared from the southern parts of the state and never gained a foothold anywhere else in the country. As of April 24, it made up only 3.2 percent of all virus samples tested in the country, while B.1.1.7 rose to 66 percent.

“B.1.1.7 went to knockout and it’s like ‘Bye bye, California variant’,” said Dr. Andersen.

Across the country, researchers reported in February that a variant called B.1.526 spread quickly in New York and appeared to be a formidable opponent for B.1.1.7. By February, each of these variants was down to about 35 percent of the Dr. Grubaugh’s Connecticut laboratory has grown. But B.1.1.7 has the edge.

Updated

May 16, 2021, 6:13 p.m. ET

In fact, B.1.1.7 seems to have an advantage over almost every variant identified so far. At a congressional hearing on Tuesday, Dr. Rochelle P. Walensky, director of the Centers for Disease Control and Prevention, that B.1.1.7 accounts for 72 percent of cases in the country.

“We really see how B.1.1.7 decisively pushes out other variants,” said Emma Hodcroft, epidemiologist at the University of Bern.

The variants identified in California and New York were found to be only moderately more contagious than older versions of the virus, and much of their initial success may have been luck. The general boom in cases last fall exacerbated what might otherwise have gone undetected.

It is unclear what gives B.1.1.7 an advantage over the others. “Is it the largest of all the variants? It’s hard to tell right now, ”said Angela Rasmussen, virologist at the University of Saskatchewan’s Vaccines and Infectious Diseases Organization. “We need more research to find out what all these combinations of mutations do.” Some of the answers may come from California, where researchers are holding a head-to-head competition in a laboratory and injecting mice with a cocktail of B.1.1.7 and six other variants.

“The idea is to see who will prevail,” said Dr. Charles Chiu, a virologist at the University of California at San Francisco, who was the first scientist to discover the California variant.

In Michigan, one of the few states to see an increase in projected cases this spring, B.1.1.7 found a catch in younger people returning to school and engaging in contact sports.

“Because it’s more transmissible, the virus finds behavioral cracks that normally wouldn’t have been as problematic,” said Emily Martin, an epidemiologist at the University of Michigan.

But in the rest of the country, of course, people became more cautious when faced with the terrible numbers of the virus after the holidays. B.1.1.7 is thought to be about 60 percent more contagious than previous forms of the virus, but the way it spreads is no different. Most states had at least partial restrictions on indoor eating and introduced mask mandates.

“B.1.1.7 is more transferable but cannot jump through a mask,” said Dr. Hodcroft. “So we can still stop its spread.”

However, other experts are still concerned about how much the virus appears to have defied predictions.

“I can’t necessarily attribute it to behavior,” said Sarah Cobey, an evolutionary biologist at the University of Chicago. Respiratory viruses sometimes go through seasonal cycles, but it’s not clear why the coronavirus cycle would have caused it to go back in the middle of winter. “That might make me even more ignorant,” she said.

It is also puzzling why variants that have beaten other countries have not yet become widespread in the United States. B. 1,351 rapidly dominated South Africa and several other African countries late last year. It was first reported in the US on January 28, but it still only accounts for 1 percent of the cases. This may be because it is not ahead of the rapidly expanding B.1.1.7.

“I think that’s because it doesn’t really have much of a transmission benefit,” said William Hanage, an epidemiologist at Harvard TH Chan School of Public Health.

P.1, a variant that is devastating Brazil, got off to a sluggish start in the US but is now estimated to account for more than 10 percent of the country’s cases.

“I think it is a matter of time before the P.1 variant becomes one of the most widespread in the US,” warned Dr. André Ricardo Ribas Freitas, a medical epidemiologist at the Faculdade São Leopoldo Mandic in Brazil.

Still, Nels Elde, an evolutionary biologist at the University of Utah, said the events of the past four months had raised questions about whether it was worth fretting over different variations rather than focusing on the behaviors that can limit them all.

“We split the hair between a handful of mutations here and there, we lost perspective,” he said. “It’s catnip for an inquisitive mind.”

The United States also has a plethora of powerful vaccines that make variants an academic problem rather than a concern for the average person. The vaccines may be slightly less effective against the variants identified in South Africa and Brazil, but prevent serious illness in all known variants.

It is not impossible that the situation could get worse. Only about 35 percent of people in the United States are fully immunized, and protection from the vaccines could wear off by winter. Nobody knows how variants that appear in other parts of the world, like one that has grown in importance in India and is circulating at a low level in the US, will behave here. And even more variants will inevitably appear in places where the virus is widespread, warned Dr. Cobey: “There is still a lot to be done.”

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World News

Singapore to close faculties as coronavirus instances rise

People take their lunch break in the Raffles Place financial district in Singapore on May 5, 2021.

Facebook Facebook Logo Log in to Facebook to connect with Roslan Rahman AFP | Getty Images

Singapore will close most schools from Wednesday after the city-state reported the highest number of local COVID-19 infections in months, including several that were unrelated, on Sunday, according to authorities.

All primary, secondary and junior colleges will switch to full home learning from Wednesday through the end of the school year on May 28th.

“Some of these (virus) mutations are much more virulent and seem to attack younger children,” said Education Minister Chan Chun Sing.

On Sunday, Singapore confirmed 38 locally transmitted COVID-19 cases, the highest daily number since mid-September, of which 18 are currently unlinked.

Singapore has reported more than 61,000 virus cases, with the majority linked to dormitory outbreaks of foreign workers last year and 31 deaths. The new cases on Sunday were the highest number of local infections outside of the dormitories in a year.

“The surge in the number of community cases today requires us to significantly reduce our movements and interactions in the coming days,” added Chan.

The Asian commercial and financial center with 5.7 million inhabitants had until recently reported almost zero or single-digit daily infections locally for months.

Although Singapore’s daily cases are still only a fraction of the numbers reported among its Southeast Asian neighbors, infections have increased in recent weeks. As of Sunday, the government rolled out its toughest restrictions on gatherings and public activities since a lockdown last year.

Over a fifth of the country’s population has completed the vaccination schedule with two doses of vaccines from Pfizer-BioNTech and Moderna. The authorities will invite people under 45 years of age to take pictures from the second half of May.

The speed of the vaccination program in Singapore is limited by the pace of arrival of vaccine supplies. Experts are investigating whether to give a dose of the vaccine and lengthen the interval between shots, Health Minister Ong Ye Kung said.

The government is also working on plans to vaccinate children under the age of 16 once regulatory approval is granted.

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Health

Sophomore 12 months 2020: College students Wrestle With the Coronavirus Pandemic

Before the pandemic, he would have said he was a kid on his way to a scholarship, maybe even to a college like Northwestern, where his father briefly studied before dropping out. When obsessed with the musical Hamilton in seventh grade, he read the Federalist Papers to see what they had to say. He played as Macbeth in a school production and liked it so much that he read other Shakespeare plays for fun. He never wanted to sound conceited, but in the past he would have said school came easily. At the same time, he found it all overwhelming at times. As a black teenager now approaching six feet, he was very much aware of what his mother’s – a PhD school administrator – expected were. – went against the expectations of the rest of the world. “To keep proving these stereotypes wrong,” he said, “it costs me a lot.”

And then, last spring, when the school closed its doors, he was left alone with thoughts that had been waiting for that very opportunity – for an enormous amount of time and space. These new thoughts flooded in, leaving little room for concern about Othello’s motivation or the subjunctive in French. More and more, when he was alone in his room there was only one voice, and that voice told Charles that no matter how promising his start was, that he would surely follow what he saw as his father’s downward slide felt. His fate was failure.

During the first few days of the school year, Charles’ laptop kept crashing during Zooms, which felt like a metaphor for what the year would bring: a big mess, a break, a technological headache he was left to solve. In the following weeks the days were empty and long; The more time that voice had, the louder it got and the harder it was to get out of it. Since he did all of his chores in his bedroom, it was easy to go back to sleep after his first grade if he made it to his first grade. “When I woke up, I could either a) get up and do what I had to do,” he said, trying to grasp his typical schedule, “or b) look at the time, be disappointed in myself, and go back to bed . “During distance learning, attendance was not included in a student’s final grade. However, Charles not only skipped class – he hardly gave any assignments. And suddenly there he was, no longer a kid getting A, but a kid who it had blown so early in the semester.

The voice in his head exhausted him so that Charles began to sleep more during the day. Sometimes the voice frightened him. His heart would start pounding and he would feel overwhelmed by a sense of an impending crisis: it was all over and there was nothing he could do about it. It was too late.

How could EK possibly get him out of the hole he was in? She had no idea how big it was already. At the beginning of October he decided to stay with Zoom after class when she offered to help all the students who were left behind. At least he could tell his mother that he had tried. He stayed and Sarah, a classmate everyone liked. She cheered and he played JV football, but they didn’t move in the same circles. She really was a smiley face – he considered her one of those people who were always happy.

When Sarah stayed After class to attend this additional help session with Ms. EK in early October, she was surprised to see Charles was there too. Charles, she had already learned, was smart. He often had an answer to everything Mrs. EK asked; In fact, the students had quickly come to rely on him to save them all from the silence that often hung in the air in their online classes. While talking to each other and Ms. EK that day, Charles and Sarah quickly found common ground and diagnosed their common problems: lack of motivation, loneliness, a feeling of hopelessness. Charles suggested that Sarah might need help, to which Sarah said, What about you?

During that conversation, Sarah told the first of many lies she would tell her teachers, mother, and herself over the coming months. OK, she would say, I’m ready to turn a new leaf. Now I’m really going to apply. But she still rarely made it to class. When her laptop died in the middle of a zoom, she decided that this was God’s way of telling her that she had done enough for the day. About six weeks into school, her mother, whose health was still shaky, whose mind was still foggy, looked at a mid-term academic assessment that landed in her email inbox and said, “What do all these NHIs mean?” Sarah said : “Huh, I don’t know”, as if she wanted to decipher one of the great bureaucratic secrets of her time, although she knew exactly what they stood for: not given up. She got used to piling up emails from teachers. “Just make sure you saw. … “” A reminder that your essay. … ”Everyone wanted something from her. Whoa, whoa, whoa. She would come back to them – someday.

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Business

Seychelles Sees Rise in Coronavirus Circumstances Regardless of Vaccinations

Marie Neige, a call center operator in the Seychelles, really wanted to be vaccinated. Like the majority of residents of the tiny island nation, she received China’s Sinopharm vaccine in March and should be fully protected in a few weeks.

She tested positive for the coronavirus on Sunday.

“I was shocked,” said Ms. Neige, 30, who is isolated at home. She said she had lost her sense of smell and taste and had a slight sore throat. “The vaccine should protect us – not from the virus, but from the symptoms,” she said. “I took precautionary measures after precautionary measures.”

China expected its Sinopharm vaccines to be the linchpin of the country’s vaccine diplomacy program – an easy-to-carry dose that would protect not only Chinese citizens but much of the developing world as well. China has donated 13.3 million doses of Sinopharm to other countries to gain goodwill, according to Bridge Beijing, a consulting firm tracking China’s impact on global health.

Instead, the company that made two types of coronavirus vaccines faces growing questions about the vaccinations. First, there was a lack of transparency in the late-stage experimental data. Now, Seychelles, the world’s most vaccinated nation, has seen increases in some cases, despite the fact that much of its population has been vaccinated with Sinopharm.

For the 56 countries that are counting on Sinopharm’s shot to stop the pandemic, the news is a setback.

For months, public health experts had focused on bridging the access gap between rich and poor nations. Now scientists are warning that developing countries that choose to use the Chinese vaccines, with their relatively weaker efficacy rates, could lag behind those choosing vaccines from Pfizer-BioNTech and Moderna. This loophole could allow the pandemic to continue in countries with fewer resources to fight the pandemic.

“You have to be using really powerful vaccines to get this economic benefit or you will be living with the disease long term,” said Raina MacIntyre, who heads the biosecurity program at the Kirby Institute, University of New South Wales in Sydney, Australia. “The choice of vaccine is important.”

Nowhere have the consequences been more apparent than in the Seychelles, which relied heavily on a Sinopharm vaccine to vaccinate more than 60 percent of their population. The tiny island nation in the Indian Ocean, northeast of Madagascar and with a little over 100,000 inhabitants, is fighting a wave of the virus and had to impose another lockdown.

Of the vaccinated population who received two doses, 57 percent received Sinopharm while 43 percent received AstraZeneca. Thirty-seven percent of the new active cases, according to the Ministry of Health, are fully vaccinated people who did not indicate how many people among them received the Sinopharm shot.

“At first glance, this is an alarming finding,” said Dr. Kim Mulholland, a pediatrician at Murdoch Children’s Research Institute in Melbourne, Australia who has been involved in overseeing many vaccine studies, including those for a Covid-19 vaccine.

Dr. Mulholland said the first reports from the Seychelles correlate with a 50 percent rate of effectiveness for the vaccine instead of the 78.1 percent rate the company has touted.

“We would expect in a country where the vast majority of the adult population has been vaccinated with an effective vaccine to see the disease melt away,” he said.

Scientists say breakthrough infections are normal because no vaccine is 100 percent effective. The Seychelles experience, however, is in stark contrast to Israel, which has the second highest vaccination rate in the world and has managed to fight back the virus. A study showed that the Pfizer vaccine used by Israel was 94 percent effective at preventing transmission. On Wednesday, the number of new confirmed Covid-19 cases per million people in the Seychelles stood at 2,613.38 compared to 5.55 in Israel, according to The World In Data project.

Updated

May 12, 2021, 12:34 p.m. ET

Wavel Ramkalawan, the President of Seychelles, defended the country’s vaccination program, saying that the vaccines against Sinopharm and AstraZeneca “have served our people very well”. He pointed out that the Sinopharm vaccine was given to people aged 18 to 60, and that in that age group, a total of 80 percent of patients who had to be hospitalized were not vaccinated.

“People may be infected, but they are not sick. Only a small number, ”he told the Seychelles News Agency. “So what happens is normal.”

Minister for Foreign Affairs and Tourism Sylvestre Radegonde said the surge in cases in Seychelles was partly due to people abandoning their vigilance, according to the Seychelles News Agency. Sinopharm did not respond to a request for comment.

In response to a Wall Street Journal article on Seychelles, a Chinese Foreign Ministry spokeswoman accused the Western media of attempting to discredit Chinese vaccines and “cultivating the mentality that” everything related to China must be smeared “.

In a press conference, Kate O’Brien, director of vaccinations at the World Health Organization, said the agency assessed the rise in infections in the Seychelles and called the situation “complicated”. Last week the global health group approved the Sinopharm vaccine for emergency use, raising hopes of an end to the global supply crisis.

She said that “some of the cases that are reported occur either shortly after a single dose, or shortly after a second dose, or between the first and second dose.”

According to Ms. O’Brien, WHO is studying the strains currently circulating in the country, when the cases occurred, relative to when someone was dosed and the severity of each case. “Only through this type of assessment can we judge whether or not it is vaccination failure,” she said.

However, some scientists say it is becoming increasingly clear that the Sinopharm vaccine does not offer a clear path to herd immunity, especially considering the numerous variants that appear around the world.

Governments using the Sinopharm vaccine must “accept a significant failure rate and plan accordingly,” said John Moore, a vaccine expert at Cornell University. “You need to make the public aware that you still have a good chance of getting infected.”

Many in Seychelles say the government was not ready.

“My question is, why did you push everyone to take it?” said Diana Lucas, a 27-year-old waitress who tested positive on May 10th. She said she received her second dose of the Sinopharm vaccine on February 10th.

Government attorney Emmanuelle Hoareau, 22, tested positive on May 6th after the second dose of the Sinopharm vaccine in March. “It doesn’t make sense,” she said. She said the government failed to provide enough information about the vaccines to the public.

“They don’t explain the real situation to people,” she said. “It’s a big deal – a lot of people get infected.”

Ms. Hoareau’s mother, Jacqueline Pillay, is a nurse at a private clinic in Victoria, the capital. She believes there is a new variant in the Seychelles because a lot of foreigners have arrived in the last few months. The tourism-dependent country opened its borders to most travelers without quarantine on March 25.

“People are very scared now,” said Ms. Pillay, 58. “If you gave people the right information, people wouldn’t speculate.”

Health officials recently appeared on television to encourage those who only took the first dose of the Sinopharm vaccine to come back for the second shot. But Ms. Pillay said she was frustrated that the public health officer hadn’t addressed why the vaccines don’t seem to be working as well as they should.

“I think a lot of people don’t come back,” said Ms. Pillay.

Marietta Labrosse, Elsie Chen, and Claire Fu have contributed to the research.

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Health

Airborne Coronavirus Is a Risk, the C.D.C. Acknowledges

The federal health authorities updated the public guidelines on the spread of the coronavirus on Friday, emphasizing that the transmission occurs through inhalation of very fine respiratory droplets and aerosolized particles, as well as through contact with sprayed droplets or by touching contaminated hands with the mouth, nose or eyes.

The Centers for Disease Control and Prevention now explicitly state – in large, bold letters – that airborne viruses can be breathed even if you are more than three feet from an infected person. The new language, released online, is a change from the agency’s previous position that most infections were acquired through “close contact, not airborne transmission”.

As the pandemic played out last year, infectious disease experts warned for months that both the CDC and the World Health Organization were overlooking research that strongly suggested the coronavirus was floating in the air in small particles. Several scientists on Friday welcomed the agency’s abolition of the term “close contact”, which they criticized as vague and which did not necessarily capture the nuances of aerosol transfer.

“Now the CDC has caught up with the latest science, got rid of some old problematic terms and thought about how the transmission happens,” said Linsey Marr, aerosol expert at Virginia Tech.

The new focus underscores the need for the federal agency for occupational safety and health to issue standards for employers to address potential hazards in the workplace, some experts said.

“They hadn’t talked much about aerosols and focused more on droplets,” said David Michaels, an epidemiologist at the George Washington School of Public Health and head of OSHA in the Obama administration.

He and other researchers expressed concern that the CDC has not yet reaffirmed its recommendations on preventing exposure to aerosolized viruses.

The new information has a significant impact on the indoor climate and especially on the workplaces, said Dr. Michaels. Virus-laden particles “retain their properties in the air for hours and accumulate in a room that is not well ventilated.”

“There’s more exposure closer,” said Dr. Michaels. “But if you are further away there is still a risk, and those particles are still in the air.”

Donald Milton, an aerosol scientist at the University of Maryland, agreed that federal officials should come up with better guidelines for workplace safety.

“We need to better focus on good breathing apparatus for people who have to be around other people for long periods of time,” said Dr. Milton. “A surgical mask, even if it’s hidden around the edges, still doesn’t give you enough protection when you’re elbow-to-elbow with other people in a meat packing facility.”

Health care workers, bus drivers, and other workers may also need respirators, said Dr. Michaels. Customers in retail stores should continue to keep their distance and wear masks, he added. Good ventilation is of the utmost importance with these settings.

Dr. Marr pointed out that an updated page on the CDC website entitled “How Covid-19 Spreads” states that inhaling the virus when people are far apart is “unusual”. The statement is “misleading and potentially harmful,” said Dr. Marr.

“If you are in a poorly ventilated area, a virus will build up in the air and everyone in that room will be exposed.”

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Health

Need a Coronavirus Vaccine? U.S. Pharmacies Say Stroll Proper In

Just a few weeks ago, people were sneaking across state lines, designing websites to search the internet, and even trying to pay for coronavirus vaccination appointments.

In much of the US, getting vaccinated can be as simple as entering a pharmacy.

Earlier this week, President Biden urged pharmacies to provide walk-in vaccinations to encourage reluctant people to get the shot. He also announced a new federal website and phone number that will help people find the website that is closest to them.

“We’re going to make it easier than ever to get vaccinated,” Biden said on Tuesday.

Chains like Walmart, Walgreens, Safeway, and Stop & Shop have announced that they are now offering vaccinations for walk-in customers in some locations or in mobile clinics. Other pharmacies preceded the president’s announcement. Rite Aid said there would be a limited number of walk-ins last week, for example. Biden’s administration is expanding access to meet its goal of getting at least the first shot at 70 percent of American adults by July 4th.

Many of the chains qualified the offer and found that walk-ins are subject to availability and that it is better to make an appointment on the same day as well.

Federal health officials have also ordered drug stores and grocery pharmacies to offer second doses of the vaccine to people who received their first shot from another provider.

The Biden government is hoping for a surge in vaccinations before the Food and Drug Administration expects the Pfizer BioNTech vaccine to be approved for adolescents ages 12-15 early next week. The president has said age group is important in the fight against the virus because, while adolescents are not as susceptible to serious illnesses, they can still get sick and infect others.

Convenience isn’t the only way officials have encouraged people to get vaccinated. In exchange for a free vaccination against a potentially fatal disease, you can now get a ticket to a baseball game, a stiff drink, or $ 100.

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Business

IPL suspended indefinitely over coronavirus considerations

Bowler Trent Boult from Delhi Daredevils plays against the Rajasthan Royals during an IPL cricket match.

Vishal Bhatnagar | NurPhoto | Getty Image

The 2021 Indian Premier League has been suspended amid concerns about coronavirus levels in the country.

The number of new coronavirus infections in India exceeded 20 million on Tuesday. 357,229 new cases have been reported in the past 24 hours, adding further strain to an already overwhelmed health system.

Three Australian cricketers – Adam Zampa, Kane Richardson and Andrew Tye – have already dropped out of their IPL season to go home while Indian weirdo Ravichandran Ashwin has taken a break to spend time with his family.

The regular season should end on May 23rd. Qualifiers and eliminators should follow before the final on May 30th.

“The Indian Premier League Governing Council (IPL GC) and the Board of Control for Cricket in India (BCCI) unanimously decided in an emergency meeting to postpone the IPL 2021 season with immediate effect,” said an IPL statement.

“BCCI does not want to compromise on the safety of players, support staff and other participants involved in organizing the IPL. This decision was made with the safety, health and wellbeing of all involved in mind.

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“These are difficult times, especially in India, and while we have tried to bring something positive and cheer, it is imperative that the tournament is now suspended and everyone returns to their families and loved ones during these difficult times.”

Three Australian cricketers – Adam Zampa, Kane Richardson and Andrew Tye – have already dropped out of their IPL season to go home while Indian weirdo Ravichandran Ashwin has taken a break to spend time with his family.

Several English players – including Captain Eoin Morgan, Jos Buttler, Jonny Bairstow and Moeen Ali – took part in the tournament. The ECB had already announced on Tuesday that the decision on whether or not to continue participating would be left to the individual.

People like Buttler, Bairstow and Ali, who are members of the English testing team, had the chance to miss England’s five-day streak against New Zealand in early June, but the postponement of the IPL could cause them to become available.

The statement goes on to say: “The BCCI will do everything in its power to ensure the safe passage of all participants in IPL 2021.

“The BCCI would like to thank all employees in the healthcare system, government associations, actors, support staff, franchise companies, sponsors, partners and all service providers who have done their best to organize IPL 2021 even in these extremely difficult times.”

In this image, taken on October 10, 2020, a taxi drives past a hoard of Mumbai Indian cricket players at the Indian Premier League (IPL) cricket tournament in Mumbai.

INDRANIL MUKHERJEE | AFP | Getty Images

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Health

Biden Confronts Coronavirus Vaccine Patents

WASHINGTON – President Biden is under increasing pressure from the international community and his party’s left flank to improve vaccine supplies by easing the protection of patonavirus vaccines through patents and intellectual property in the face of the escalating Covid-19 crisis in India and South America commit.

Pharmaceutical and biotech companies, which were also under pressure, tried on Monday to prevent such a move, which could detract from future profits and jeopardize their business model. Pfizer and Moderna, two major vaccine manufacturers, each announced steps to expand the supply of vaccines around the world.

The issue came to a head when the General Council of the World Trade Organization, one of its highest decision-making bodies, met on Wednesday and Thursday. India and South Africa are pressing for the panel to renounce an international intellectual property treaty protecting the trade secrets of pharmaceuticals. The United States, Britain and the European Union have so far blocked the plan.

In the White House, the president’s health advisors admit they’re divided. Some say Mr. Biden has a moral imperative to act and that it is bad policy for the president to side with the pharmaceutical executives. Others say spilling closely guarded but highly complex trade secrets would do nothing to expand the global vaccine supply.

Having the prescription for a vaccine doesn’t mean a drug company could make it, especially not quickly, and opponents argue that such a move would harm innovation and entrepreneurship – and harm America’s pharmaceutical industry. Instead, it is said, Mr. Biden can address global needs in other ways, such as by urging companies that own patents to donate large quantities of vaccines or sell them at cost.

“That would be a terrible precedent for the industry,” said Geoffrey Porges, an analyst at investment bank SVB Leerink. “It would be extremely counterproductive in the extreme because what it would tell the industry is, ‘Don’t work on something that is really important to us because if you do, we’ll just take it away from you. ‘”

Dr. Anthony S. Fauci, Mr. Biden’s senior medical advisor for the pandemic, said in an interview Monday that drug manufacturers must act themselves, either by significantly expanding their manufacturing capacity to serve other nations at “an extremely reduced price” , or by transferring their technology to make cheap copies in the developing world. He said he was agnostic about giving up.

“I always respect the needs of companies to protect their interests in order to keep them in business, but we cannot do this fully if we don’t allow life-saving vaccines to get to the people who need them,” said Dr. Fauci, adding, “You can’t let people around the world die because they don’t have access to a product that rich people have access to.”

For Mr Biden, the surrender debate is both a political and a practical issue. As a presidential candidate, he promised liberal health activist Ady Barkan, who suffers from amyotrophic lateral sclerosis (ALS), that he would be “absolutely positive” for technology sharing and access to a coronavirus vaccine if the US developed one first. Activists plan to remind Mr. Biden of this pledge during a rally scheduled for Wednesday in the National Mall.

“He’s not brave about this,” said Gregg Gonsalves, a Yale epidemiologist who fought similar battles during the AIDS crisis of the 1980s and 1990s and is expected to speak at the rally. “That’s what you said during the AIDS epidemic. Still, the same excuses come from 20 years ago. “

India and South Africa’s proposal would exempt World Trade Organization member countries from enforcing some patents, trade secrets or pharmaceutical monopolies under the agency’s trade-related intellectual property agreement known as TRIPS. The idea would be to allow pharmaceutical companies in other countries to make or import cheap generic copies.

Proponents say the waiver would allow innovators in other countries to pursue their own coronavirus vaccines without fear of patent infringement lawsuits. They also note that the proposed waiver goes beyond vaccines to include intellectual property for therapeutics and medical supplies.

“A lot of people say, ‘Don’t you need the secret recipe? “That’s not necessarily the case,” said Tahir Amin, founder of the Drugs, Access and Knowledge Initiative, a nonprofit dedicated to eliminating health inequalities. “There are companies that feel they can do it on their own, provided they don’t have to look over their shoulder and feel like they are taking over someone’s intellectual property.”

The pharmaceutical industry counters that withdrawing intellectual property protection would not help boost vaccine production. It is said that other issues around the world act as barriers to shooting up, including access to raw materials and distribution challenges in the field.

Updated

May 3, 2021, 8:53 p.m. ET

Just as important as the right to manufacture a vaccine is the technical expertise that must be provided by vaccine developers like Pfizer-BioNTech and Moderna – a process known as technology transfer.

Sharon Castillo, a Pfizer spokeswoman, said the company’s vaccine required 280 components from 86 suppliers in 19 countries. They also need highly specialized equipment and employees as well as complex and time-consuming technology transfers between partners and global supply and manufacturing networks.

“We just find it unrealistic to believe that doing without it makes startup easier so quickly that the supply problem can be addressed,” she said.

On Monday, Pfizer CEO Albert Bourla announced on LinkedIn that his company will donate over $ 70 million worth of drugs to India immediately and is also trying to expedite the vaccine approval process in India. The company also posted on Twitter promising “the greatest humanitarian relief effort in the history of our company to help the people of India”.

Moderna, which developed its vaccine with US taxpayer funding, has already announced that it will “not enforce our patents related to Covid-19 against those who make vaccines to fight the pandemic.” But activists are not only calling for a waiver, but also for companies to share their expertise in setting up and running vaccine factories – and for Mr. Biden to rely on it.

More than 170 former heads of state and Nobel Prize winners last month, including Gordon Brown, the UK’s former Prime Minister; Ellen Johnson Sirleaf, the former President of Liberia; and François Hollande, the former President of France, issued an open letter asking Mr Biden to support the proposed waiver.

On Capitol Hill, 10 Senators, including Bernie Sanders, independent of Vermont, and Elizabeth Warren, Democrat of Massachusetts, urged Mr. Biden to “give people priority over pharmaceutical company profits” and to reverse the Trump administration’s opposition to renunciation . More than 100 House Democrats have signed a similar letter.

“This is one of the most important moral questions of our time,” said Representative Ro Khanna, Democrat of California. “Denying other countries the ability to make their own vaccines is just cruel.”

Katherine Tai, Mr. Biden’s sales representative, has held more than 20 meetings in the past few weeks with various stakeholders – including global health activists, pharmaceutical executives, members of Congress, Dr. Fauci and the philanthropist Bill Gates – to find a way forward.

“Ambassador Tai reiterated that the Biden Harris administration’s top priority is to save lives and end the pandemic in the United States and around the world,” Ms. Tai’s office said in a carefully worded statement Monday after she had spoken about the proposed waiver with the government director-general of the World Intellectual Property Organization, an arm of the United Nations.

In a letter to Ms. Tai last month, the Biotechnology Innovation Organization, a trade group, warned against licensing other countries – some of them our economic competitors – to undermine our world-leading biotechnology base, export jobs overseas, and undermine incentives to invest in such technologies in the future. “

One of the pharmaceutical industry’s concerns about a patent waiver for coronavirus vaccines is that a precedent could be created that undermines intellectual property protection for other drugs that are central to making money.

“The pharmaceutical industry is extremely protective of its intellectual property,” said Dr. Aaron Kesselheim, Professor of Medicine at Harvard Medical School and Brigham and Women’s Hospital. “This kind of violent resistance is a reflex from the pharmaceutical industry.”

However, it is not seen that such a move would have any impact on intellectual property protection for other treatments after the coronavirus crisis ended in the particular circumstances of the pandemic, industry researchers said.

In the 2000s, a handful of governments, including the Brazilian and Thai, bypassed patents of the developers of antiviral drugs for HIV / AIDS, paving the way for lower-cost versions of the treatments.

However, HIV drugs involve a much simpler manufacturing process than the coronavirus vaccines, especially those using messenger RNA technology that have never been used in an approved product.

On a Twitter thread, Mr. Amin offered another example: In the 1980s, Merck and GlaxoSmithKline had developed recombinant hepatitis B vaccines and had a monopoly of more than 90 patents on manufacturing processes. The World Health Organization recommended vaccination for children, but it was expensive – $ 23 per dose – and most Indian families couldn’t afford it.

The founder of Shantha Biotechnics, an Indian manufacturer, was told that “even if you can afford to buy the technology, your scientists cannot in the least understand the recombinant technology,” wrote Amin.

But Shantha, he added, went on to “make India’s first homegrown recombinant product for $ 1 a dose”. This enabled UNICEF to run a mass vaccination campaign.

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World News

How Can the Olympics Defend 78,000 Volunteers From the Coronavirus?

TOKYO – For Olympic host cities, one of the keys to successful games is having an army of volunteers gleefully performing a range of tasks, such as: B. fetching water, driving Olympic vehicles, interpreting for athletes or taking medals to ceremonies.

If the planned games in Tokyo take place as planned this summer, around 78,000 volunteers will have another responsibility: They will prevent the spread of the coronavirus both among the participants and among themselves.

For protection, the volunteers are only offered a couple of cloth masks, a bottle of disinfectant, and mantras about social distancing. Unless they qualify for vaccination through Japan’s slow age-dependent rollout, they will not be vaccinated against the coronavirus.

“I don’t know how we can do this,” said Akiko Kariya, 40, a paralegal in Tokyo who volunteered to be an interpreter. The Olympic Committee “didn’t tell us exactly what they were going to do to protect us.”

While organizers have gone out of their way to reassure the globe that Tokyo can end the Games amid a pandemic, volunteers are largely on their own figuring out how to avoid infection.

Much of the planning for the postponed Olympics has seating quality. Less than three months before the opening ceremony, the organizers still have to decide whether to allow local spectators.

An update to the “Game Books” released last week says that those who come in regular contact with athletes are tested, in principle, daily, while those who do not interact with athletes are tested every seven days during their Olympic participation .

Tens of thousands of participants will come to Tokyo from more than 200 countries after almost a year of largely closing Japan’s borders to outsiders. The volunteer duties will put them in contact with many Olympic visitors as they step in and out of a “bubble” that encompasses the Olympic Village and other venues.

“There are many people who have to go in and out of the bladder and they are not protected at all and are not even tested,” said Barbara G. Holthus, volunteer and deputy director of the German Institute for Japanese Studies in Tokyo. “I see the risk of a superspreader event.”

A leaflet distributed to volunteers recommends asking visitors to stand at least three feet away from each other. You should disinfect your hands frequently during the shift. When offering help to someone, avoid facing the other person directly and never speak without a mask.

“Wearing masks and washing hands are very easy, but doing the maximum is the most important thing we can do,” said Natsuki Den, senior director of volunteering on the Tokyo Organizing Committee.

“People often say, ‘It’s that simple, is that all you can do? “Said Ms. Den. But when every volunteer implements these basic measures, she said,” That can really limit the risk. Furthermore, it’s hard to imagine magical countermeasures because they don’t really exist. “

While the majority of the Japanese public continues to oppose hosting the Olympics this year, many volunteers say they are at least in principle committed to promoting the international community after more than a year of isolation. (The number of volunteers has had a noticeable success with approximately 1,000 volunteers quitting after the first president of the Tokyo Organizing Committee, Yoshiro Mori, made sexist comments.)

However, volunteers worry about their own health, as well as the safety of athletes and other Olympic participants, especially as Tokyo has new spikes in virus cases. The capital is currently in a state of emergency.

“I’m afraid I’ll get the virus and show no symptoms and accidentally give it to the athletes,” said Yuto Hirano, 30, who works for a tech company in Tokyo and is supposed to help athletes behind the scenes at Paralympic events, bocce, a Ball sports. “I want to protect myself so that I can protect them.”

In addition to the Olympic volunteers, the organizers will need to recruit medical personnel for the staff of the Games. Doctors and nurses usually volunteer at the Olympics too, but this year healthcare workers have started to reluctance as the medical system was overwhelmed after a year of fighting the coronavirus.

“We are surprised by the conversation calling for 500 nurses to be sent to the Tokyo Olympics,” the Japanese Federation of Medical Workers’ Unions said in a statement posted on its website, adding, “Now is not that Time for the Olympics. ” It’s time to take countermeasures against coronavirus. “

As the pandemic rages on, some non-medical volunteers will go to great lengths to ensure safety. Yoko Aoshima, 49, who teaches English at a business school in Shizuoka, about 90 miles outside of Tokyo, has booked a hotel for the days she is supposed to work, which costs 110,000 yen, or about $ 1,000. That means she doesn’t have to commute.

To avoid public transportation in Tokyo, she plans to buy a bike when she arrives in Tokyo to commute to the field hockey stadium where she’s assigned shifts.

But Ms. Aoshima, who volunteered in part to honor the legacy of her father, a former physical education teacher, wonders how she will protect her family when she returns home after the Games.

“If I go back to Shizuoka, will it be safe enough for my family to stay with me?” Ms. Aoshima asked. “Can I go back to work?” She said she had already bought some home coronavirus tests for use after the Olympics.

For volunteers who have spent the last year avoiding the crowds, the concept of suddenly coming into contact with athletes, coaches, officials, or media representatives from outside Japan creates a sense of cognitive dissonance.

“I only saw one friend last year when she had a baby,” said Ms. Kariya, the Tokyo paralegal. “I go to the supermarket or the bank where I really have to go. The last time I took the train was last March. “

In the absence of further security measures, Ms. Kariya said she was considering quitting as a volunteer.

Many volunteers are disappointed that they are not offered vaccines before the games. So far, organizers have stated that they are not considering giving priority to Japan’s Olympic athletes for vaccination, let alone volunteers.

“You can’t say it’s priority because then people would start yelling at you,” said Chiharu Nishikawa, 61, who passed Charles. He volunteered for the Olympic Games in Rio de Janeiro in 2016 and London in 2012 and advises the Olympic Committee on volunteering.

Some volunteers said they were concerned that the organizers did not have the resources to monitor everyone for compliance with the rules. These include wearing masks, avoiding eating in restaurants, and avoiding public transportation.

Ms. Holthus said volunteers could be taken to a difficult place as their main job is to project an image of harmonious hospitality.

A handbook for volunteers published ahead of the Olympics last year encouraged them to “speak to people with a smile”. In online sessions and other messages since then, Ms. Holthus has said, “You still say, ‘Oh, and your smile will be so important. ‘“

“We’re supposed to wear masks,” she said. “So I find that very insensitive.”

Not every volunteer has serious safety concerns. Some said they expected broad compliance with the rules, given what is at stake.

“I think the athletes will do whatever it takes to compete in the Olympics,” said Philbert Ono, travel writer, photographer and translator.

“If we tell them to wear a mask, they will wear a mask,” he said. “When they eat, they sit far apart and apart and only look in one direction. I think they are very disciplined and know what it’s about. “

Hikari Hida contributed to the coverage.