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C.D.C. Inner Report Calls Delta Variant as Contagious as Chickenpox

The Delta variant is much more contagious, is more likely to breach vaccine protection, and can cause more serious illness than any other known version of the virus, according to an internal presentation spread within the Centers for Disease Control and Prevention.

Dr. Rochelle P. Walensky, the agency’s director, admitted on Tuesday that vaccinated people with so-called breakthrough infections of the Delta variant carry just as much virus in their nose and throat as unvaccinated people and can spread it just as easily, albeit less often.

But the internal document sets out a broader and even more somber view of the variant.

The delta variant is more transmissible as the viruses that cause MERS, SARS, Ebola, the common cold, seasonal flu, and smallpox, and according to the document copied by the New York Times, it is as contagious as chickenpox.

The immediate next step for the agency is to “realize that the war has changed,” the document reads. The content was first reported by the Washington Post on Thursday evening.

The tone of the document echoes CDC scientists’ concern about the spread of Delta across the country, said a federal official who saw the research described in the document. The agency plans to publish further data on the variant on Friday.

“The CDC is very concerned about the incoming data that Delta is a very serious threat that requires action now,” the official said.

Coronavirus Pandemic and Life Expectancy in the United States

In the US, there were an average of 71,000 new cases a day as of Thursday. The new data suggests that vaccinated people spread the virus and contribute to these numbers – albeit likely to a far lesser extent than those who were not vaccinated.

Dr. Walensky has called transmission by vaccinated people a rare occurrence, but other scientists have suggested it is more common than previously thought.

The agency’s new masking guidelines for vaccinated individuals, introduced on Tuesday, were based on information contained in the document. The CDC recommended that vaccinated people wear masks indoors in public settings in communities with high virus transmission levels.

Updated

July 31, 2021 at 11:50 p.m. ET

However, the internal document indicates that even this recommendation may not go far enough. “In view of the higher transferability and current vaccination protection, universal masking is essential,” the document says.

The agency’s data suggests that people with weak immune systems should wear masks even in places with low virus transmission. This should include vaccinated Americans who are in contact with young children, older adults, or other vulnerable people.

According to the July 24 CDC quoted in the internal presentation, there are about 35,000 symptomatic infections per week among 162 million Americans vaccinated. However, the agency does not track all mild or asymptomatic infections, so the actual incidence may be higher.

Understand the state of vaccine mandates in the United States

Infection with the delta variant produces amounts of virus in the airways that are ten times higher than in people infected with the also highly contagious alpha variant, the document says.

According to a recent study, the amount of virus in a person infected with Delta is a thousand times higher than in people infected with the original version of the virus.

The CDC document draws on data from several studies, including an analysis of a recent Provincetown, Massachusetts outbreak that began in the city after the July 4th celebrations. By Thursday, that cluster had grown to 882 cases. About 74 percent had been vaccinated, said the local health authorities.

A detailed analysis of the prevalence of the cases showed that people infected with Delta carry enormous amounts of virus in their nose and throat regardless of vaccination status, according to the CDC document.

“This is one of the most impressive examples of citizen science I’ve seen,” said Dr. Celine Gounder, an infectious disease specialist at Bellevue Hospital Center in New York. “The people involved in the Provincetown outbreak meticulously created lists of their contacts and exposures.”

Infection with the Delta variant can be more likely to lead to serious illness, the document says. Studies from Canada and Scotland found that people infected with the variant were more likely to be hospitalized, while research in Singapore suggested that they were more likely to need oxygen.

Still, the CDC’s numbers show the vaccines are highly effective at preventing serious illness, hospitalization and death in people who have been vaccinated, experts said.

“Overall, Delta is the disturbing variant that we already knew it was,” said John Moore, a virologist at Weill Cornell Medicine in New York. “But the sky is not falling and vaccinations are still very protective against the worst of the consequences.”

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CDC warns as contagious as chickenpox, could make individuals sicker

The CDC warned House lawmakers that the delta variant sweeping across the country is as contagious as chickenpox, has a longer transmission window than the original Covid-19 strain and may make older people sicker, even if they’ve been fully vaccinated.

The warning on Thursday was made in a confidential document that was reviewed by CNBC and authenticated by the federal health agency.

Delta, now in at least 132 countries and already the dominant form of the disease in the United States, is more transmissible than the common cold, the 1918 Spanish flu, smallpox, Ebola, MERS and SARS, according to the document. Only measles appears to spread faster than the variant.

“The war has changed,” officials of the Centers for Disease Control and Prevention wrote.

Healthcare personnel work in a coronavirus disease (COVID-19) intensive care unit where they are dealing with a surge in cases of the Delta variant at Intermountain Medical Center in Murray, Utah, U.S., in this handout photo provided July 23, 2021.

Intermountain Health | Reuters

Health officials said federal and state leaders should communicate to the public the benefits of getting vaccinated, adding the Covid vaccine shots reduce the risk of severe disease and death “10-fold or greater” and reduce the risk of infection “3-fold.”

Vaccines prevent more than 90% of severe disease, but may be less effective at preventing infection, they said, making community spread among the vaccinated more likely. The document said 35,000 symptomatic infections are occurring per week among 162 million vaccinated Americans.

Separately, the CDC has said 5,914 fully vaccinated people have been hospitalized or have died with Covid infections as of July 19, the most recent data available. Breakthrough cases, which occur in the fully vaccinated, happen more frequently in gatherings of people and in groups at risk of primary vaccine failure, according to the document.

Health officials also said federal and state leaders should consider vaccine mandates, particularly for health-care workers, universal masking and other community mitigation strategies. President Joe Biden announced on Thursday his administration would require federal workers to prove their vaccination status or submit to a series of rigorous safety protocols.

The documents presented to lawmakers came two days after the CDC reversed course on its prior guidance and recommended fully vaccinated Americans who live in areas with high Covid infection rates resume wearing face masks indoors. The guidelines cover about two-thirds of the U.S. population, according to a CNBC analysis.

“My first thoughts in reading it was that everything is a little bit worse than I thought,” said Dr. Robert Wachter, chairman of the Department of Medicine at the University of California at San Francisco, who reviewed the document.

“This document and some of the other information says you’ve got to be open to the possibility that delta is worse in a number of ways and may upend some of our prior assumptions in ways that are meaningful,” he said.

Dr. Paul Offit, who advises the FDA on Covid vaccines, said Friday it is “profoundly” upsetting that the U.S. hasn’t gotten a critical portion of the population vaccinated, adding delta has “changed the game.” About half of the U.S. population is fully vaccinated, according to CDC data.

“Yesterday, you had 90,000 cases and close to 400 deaths,” Offit said. “Those are same numbers you saw last summer. I mean, last summer, you had a fully susceptible population and you had no vaccine.”

He said the CDC documents highlight just how “frustrated” federal officials are, given that there are safe and effective vaccines.

“The war isn’t against the virus anymore. It’s also at some level a war against ourselves,” he said.

People infected with the delta variant carry up to 1,000 times more virus in their nasal passages than other strains, resulting in higher transmissibility, even among the vaccinated, according to federal health officials. The CDC noted that studies in Canada, Singapore and Scotland found higher odds of hospitalization, ICU admission, oxygen needs, pneumonia or death among people infected with the delta variant.

While the variant, which surfaced in India, continues to hit unvaccinated people the hardest, some vaccinated people could be carrying higher levels of the virus than previously understood and are potentially transmitting it to others, CDC Director Dr. Rochelle Walensky said Tuesday. She added the variant behaves “uniquely differently from past strains of the virus.”

“This pandemic continues to pose a serious threat to the health of all Americans,” Walensky told reporters on a call.

Rep. James E. Clyburn, D-S.C., chairman of the Select Subcommittee on the Coronavirus Crisis, said Walensky and White House chief medical advisor Dr. Anthony Fauci briefed the committee on the new data Thursday.

“I am deeply concerned about the rapidly increasing rates of coronavirus infections in states around the country that is being driven by the Delta variant,” Clyburn said in a statement, noting that Covid cases have increased by 145% in the last two weeks and hospitalizations and deaths are rising again, particularly in areas with low vaccination rates. “This sudden turn of events threatens to undermine the significant progress we have made this year to overcome the pandemic.”

–CNBC’s Rich Mendez, Robert Towey and Nate Rattner contributed to this report.

Download the full CDC presentation here.