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Hashish Was Domesticated in East Asia, New Research Suggests

By sequencing genetic samples from the plant, they found that the species was most likely domesticated in the early Neolithic. They said their conclusion is supported by pottery and other archaeological evidence from the same period discovered in what is now China, Japan, and Taiwan.

But Professor Purugganan said he was skeptical of the conclusions that the plant was developed for drug or fiber consumption 12,000 years ago, as archaeological evidence shows that cannabis was consistently used or present for these purposes around 7,500 years ago.

“I would like a much larger study with a larger sample,” he said.

Luca Fumagalli, author of the study and a biologist in Switzerland who specializes in conservation genetics, said the theory of Central Asian origin is largely based on observational data from wild samples in that region.

“It is easy to find wild samples, but they are not wild types,” said Dr. Fumagalli. “These are plants that have escaped captivity and adapted to the wild environment.”

“That’s why you call it grass, by the way, because it grows all over the place,” he added.

The study was led by Ren Guangpeng, a botanist at Lanzhou University in western China’s Gansu Province. Dr. Ren said in an interview that the original location of cannabis domestication was most likely in northwest China and that the discovery could help in the country’s current efforts to breed new strains of hemp.

To conduct the study, Dr. Ren and colleagues 82 samples, either seeds or leaves, from around the world. Samples included strains selected for fiber production and others from Europe and North America bred to produce high levels of tetrahydrocannabinol (THC), the plant’s most mood-altering compound.

Dr. Fumagalli and his colleagues then extracted genomic DNA from the samples and sequenced them in a laboratory in Switzerland. They also downloaded and re-analyzed sequencing data from 28 other samples. The results showed that the wild varieties they analyzed were indeed “historical escapes from domesticated forms” and that existing varieties in China – cultivated and wild – were their closest offspring of the ancestral gene pool.

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Medical hashish agency backed by Snoop Dogg begins buying and selling in London

Recording artist Snoop Dogg speaks on stage on day one of TechCrunch Disrupt SF 2015 at Pier 70 on September 21, 2015 in San Francisco, California.

Getty Images

LONDON – Oxford Cannabinoid Technologies, happily endorsed by rapper Snoop Dogg and tobacco giant Imperial Brands, launched on the London Stock Exchange on Friday.

The British company, which specializes in developing pain relieving cannabinoid drugs, grossed £ 16.5 million ($ 23.4 million) in gross proceeds on its IPO with a starting market value of just over £ 48 million ($ 69 million) .1 million USD).

The share price hovered around 5p on Friday lunchtime after opening near 8p.

Snoop Dogg, whose real name is Calvin Broadus Jr., has invested in several cannabis startups, including OCT, through his venture capital firm Casa Verde. His firm has also supported plant-based food companies like Outstanding Foods and tech names like Klarna, Robinhood, and Reddit.

Cannabinoids are naturally occurring compound chemicals found in the cannabis sativa plant and are commonly used for medicinal purposes to treat symptoms such as chronic pain.

OCT’s strategy is to develop cannabinoid drugs for the non-addictive treatment of painful conditions. CEO John Lucas told CNBC on Friday the company plans to use the proceeds of its IPO to develop four new drugs.

“The key here is getting cannabinoids into the hands of patients and the way you do that happens through the drug development process,” Lucas told CNBC’s Squawk Box Europe.

“With medical cannabis, the problem is that doctors can’t prescribe it, so we want a drug that we can get into the hands of doctors, into the hands of patients.”

In its listing announcement, OCT said its “primary market focus is on the total addressable pain market, valued at at least £ 42.5 billion through the commercialization of the first drug manufactured by OCT, currently expected in 2027.”

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Business

GrowGeneration seems to be east with New York nearer to legalizing hashish

Darren Lampert, CEO of GrowGeneration, told CNBC on Thursday that the company is focused on expansion on the east coast as New York State gets just inches closer to legalizing recreational marijuana.

“You will see us shortly enter the markets on the east coast,” he said in an interview with Jim Cramer about “Mad Money”.

New York lawmakers could put a bill to legalize marijuana for a vote in the congregation as early as next week, Associated Press reports. If passed, the bill is expected to be signed by Democratic Governor Andrew Cuomo.

Next door in New Jersey, marijuana is now legal for recreational use, though the state still has rules and regulations for its sale. GrowGeneration, which operates dozen of grow businesses across the country, plans to open stores in New Jersey soon.

“We are still waiting for the licensing to confirm how big the licensing will be, how restrictive it will be,” he said. “More importantly, craft licensing … unlimited craft licensing, which is great for GrowGeneration.”

GrowGeneration operates more than 50 grow shops in 12 states. Most are in the western part of the country, many in California. The company operates a handful of stores in Maine, Florida and Massachusetts.

The company sells the “picks and shovels” products like lights and hydroponics that are used to grow cannabis indoors, Lampert said.

“What you are seeing now, Jim, is a fundamental change [in] controlled environment ag, “he said.” We sell the inputs. We sell the technologies, the solutions that control the environment in which plants live. “

On Wednesday, GrowGeneration reported total annual sales of $ 193.0 million in 2020, up 143% year over year. It was the third year in a row that the company had posted triple-digit sales growth. Executives expect business to more than double again this year.

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Business

Virginia will get near legalizing leisure weed as different states eye hashish tax windfalls

A customer sets fire to a shop in Lowell Farms, America’s first official cannabis cafe serving farm-to-table dining and smoking cannabis on October 1, 2019 in West Hollywood, California.

Mike Blake | Reuters

Virginia is on the verge of becoming the first southern state to generate high tax revenues when it comes to legalizing recreational herbs.

A bill passed on Sunday Democratic Governor Ralph Northam’s signature awaits in both the State House of Representatives and the Senate.

Once signed, the Old Dominion would officially join 15 other states and the District of Columbia that have legalized marijuana for recreational adult use. Under Virginia law, legal sales and ownership would not take effect until 2024.

States from Wisconsin to Kansas – many of them strapped for money amid the Covid pandemic – are calling for similar measures as they struggle to balance their budgets. The governors also cite racial justice as a reason for legalizing marijuana. Black and Latin American men across the country are more likely to be incarcerated than their white counterparts for the same offenses.

Support for marijuana legalization has grown steadily over the years. Recent Gallup polls found that 68% of adults in the US think marijuana should be legalized for recreational use, up from 66% last year. With Democratic President Joe Biden in the White House and the party currently holding a majority in both the House of Representatives and Senate, federal marijuana legalization could be closer than ever.

For now, however, it remains a state-to-state decision.

New Jersey is the youngest to join the party. Democratic Governor Phil Murphy signed a reform bill in late February after voters approved the measure in November. A report by the bipartisan think tank New Jersey Policy Perspective estimates the state could generate at least $ 300 million in tax revenue annually.

For Virginia, legalizing pots could bring in $ 698 million to $ 1.2 billion annually in economic activity and up to $ 274 million in tax revenue annually, according to a study by the governors’ office.

Northam also acknowledged racial differences in drug abuse convictions in his most recent State of the Commonwealth address. “Reforming our marijuana laws is one way to ensure Virginia is a fairer state that works better for everyone,” he said.

Not all constituents are happy with the pace of change. The American Civil Liberties Union of Virginia said the legislation paid “lip service” but “does nothing to address the persistent racial gaps we see decriminalizing through 2024,” reported WWBT, an NBC partner in television Richmond, Virginia.

A governor’s spokesman told CNBC: “We have a lot of work to do, but this bill will help reinvest in our communities and reduce inequalities in our criminal justice system.” The spokesman said the governor’s top priority is making sure Virginia legalizes marijuana fairly.

Other governors are calling for legalization

In Pennsylvania, Governor Tom Wolf again called for marijuana legalization in his state budget address, highlighting it as a priority for this year after neighboring states either approve or are considering legalization.

“I urge lawmakers to work with me to build a foundation to strengthen the Pennsylvania economy by legalizing adult cannabis,” the Democratic governor said in a message to lawmakers in September.

The governor also highlighted racial justice as a priority for legalization. “These are proceeds that can help criminal justice-affected Pennsylvanians gain access to restorative justice programs.”

Pennsylvania blacks are three times more likely to be arrested for marijuana possession than whites, according to the state’s ACLU chapter. Wolf’s office did not respond to a request for comment.

Highlight the cons

Washington, which was one of the first states to legalize recreational herbs in 2012, made a total of $ 395.5 million in legal marijuana tax revenue and royalties in fiscal 2019, according to the state’s annual report. The legal marijuana market in the state supports more than 18,500 jobs, according to a recent study by Washington State University.

But as with many good things, there are often downsides. A University of Washington study published in the American Journal of Preventive Medicine showed that the legalization of cannabis in the state and a general change in attitudes towards the plant began to slow the downward trend in cannabis use among teenagers.

Study lead author Jennifer Bailey said, “We really don’t want teenage consumption to increase,” but added that it will be several decades before the effects of legalization are fully understood, as is the case with post-alcohol alcohol Prohibition was the case. She also highlighted racial justice, tax issues, and cannabis research as important benefits of legalization.

Many states are incorporating the language into cannabis legislation, according to which communities affected by racial inequalities in criminal justice will benefit most from legalization. But even guidelines developed for the benefit of color communities sometimes fail.

In Illinois, for example, a year after the state legalized the plant, there are still no minority-owned cannabis stores, even though the legislation includes language to limit pharmacies to give minority communities an advantage. The Illinois governor’s office did not immediately return a request for comment.

“There is a small fraction of the people who have cash and control over the money. If you have an industry and an emerging market and you can only join when you have cash, you’ve already eliminated the blacks,” said the Democratic La Shawn Ford, a member of the state legislature’s Black Caucus, told Politico.

Government shared roadblocks

States that have split government like Wisconsin may find it more difficult to pass comprehensive cannabis reform. Democratic Governor Tony Evers recently said he would propose legalizing recreational marijuana in Wisconsin, citing potential tax revenues of more than $ 165 million a year for the state.

“The legalization and taxation of marijuana in Wisconsin – just like we already do with alcohol – ensures that a controlled market and a safe product are available for both recreational and medical users, and can open up myriad opportunities for us to be in our communities to invest and create more just state, “he said in a recent statement.

With Republican lawmakers currently controlling the Wisconsin legislature, it is unlikely to pass.

Many southern states share a similar fate. Legislators in the Mississippi House and Senate are currently fighting over the language for a medical marijuana bill after a measure mandating a state medical marijuana program was approved by Mississippi voters.

In Minnesota, HF 600 was recently the first adult recreational use bill to stand out of the state’s committee. Minnesota’s Senate is controlled by Republicans and the House is controlled by Democrats, diminishing the likelihood of the bill being passed. Democratic Governor Tim Walz recently urged lawmakers to consider legalizing marijuana to boost the state’s economy in a briefing focused on his budget proposal. Comments from Walz’s office were not immediately returned.

Even election initiatives approved by voters can go up in smoke. A Circuit Court judge appointed by Republican Governor Kristi Noem recently ruled that a constitutional amendment approved by South Dakota voters to legalize recreational marijuana was unconstitutional. The ruling said the change would have “far-reaching implications for the fundamental nature” of the state government.

Recently, Democrat Laura Kelly, Kansas governor, announced a proposal to legalize medical marijuana in the deep red state to increase the revenue needed to expand Kansas’s Medicaid program to nearly 200,000 residents, who currently lack coverage. The Republican-controlled legislature is expected to reject the proposal, but Majority Leader Dan Hawkins did not take medical marijuana off the table. In a statement to Politico, he acknowledged growing support for drug reform but said it was too early to predict how the debate would develop.

In total, around 12 countries are currently considering some kind of cannabis reform legislation. States like New York, Connecticut, New Mexico, and Hawaii could soon see laws covering governors’ desks.

“It’s not about whether a deal comes about,” New York State Senate Democratic Majority Leader Andrea Stewart-Cousins ​​told the New York Times in January. “It’s about how and when.”

CORRECTION: This story has been updated to reflect the University of Washington study published in the American Journal of Preventive Medicine. In a previous version, the name of the university was incorrectly entered.

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Health

Tilray CEO expects U.S. federal hashish legalization inside two years

Brendan Kennedy, CEO of medical cannabis producer Tilray, poses in a greenhouse of the Canadian company’s European production site in Cantanhede on April 24, 2018.

Patricia De Melo Moreira | AFP | Getty Images

Brendan Kennedy, CEO of Canadian cannabis company Tilray, is optimistic that the US will take steps to federally legalize marijuana in the near future, which will shake the industry forever.

“I assume that the pressure from the north and the south will eventually cause the US to implement a federal program here sometime in the next 18 to 24 months,” said Kennedy in an interview on CNBC’s “Squawk on the Street” on Wednesday.

Mexico released regulations on medical cannabis use earlier this month, and Kennedy is confident that Mexico and Canada’s positive stance on marijuana will put more pressure on the US

Tilray announced Tuesday that it has been selected by the country’s National Agency for the Safety of Medicines and Health Products as a supplier of medical cannabis for experiments in France.

The company has been selling its cannabis products in Germany since 2017. With the French program launched in the first quarter, Kennedy is optimistic that other European countries will run medical marijuana programs as well.

“While we look forward to our opportunities in Germany and France, we expect additional opportunities for our European companies in the coming quarters,” said Kennedy in an interview with CNBC.

Tilray has licenses to produce cannabis in Canada and Portugal, where the main cannabis facility is located.

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Tilray inventory soars, firm to offer medical hashish in French examine

A worker inspects cannabis plants in the grow room of Aphria Inc.’s diamond factory in Leamington, Ontario, Canada on Wednesday, January 13, 2021. Tilray Inc. and Aphria Inc. have agreed to combine their activities to form a new giant in the fast growing cannabis industry.

Annie Sakkab | Bloomberg | Getty Images

Shares in Canadian cannabis company Tilray rose nearly 10% Tuesday after it was announced that the French government had been using it to provide cannabis for medical experiments.

The French National Agency for the Safety of Medicines and Health Products will start the 18- to 24-month study in the first quarter. Tilray’s products will treat patients with neuropathic pain, epilepsy and multiple sclerosis that are not relieved by existing treatments.

Tilray will export the medical cannabis products from its facility in Cantanhede, Portugal, which serves as the central research and development center for medical cannabis.

“Today’s announcement marks another milestone for Tilray as we expand our operations in Europe,” said Brendan Kennedy, Tilray chief executive.

Tilray stock is down about 2% in the past 12 months, increasing its market value to $ 2.53 billion.