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Health

For Sleep Apnea, a Mouth Guard Could also be a Good Different to CPAP

But many patients find sleeping with a face mask less awkward or uncomfortable than using a CPAP machine. The technical term for these devices is mandibular advancement device, so named because it pushes the mandible forward, which in most people helps keep the airway open. There are many variations of these devices in drug stores, but a dentist can design a more effective personalized device and modify or customize it if necessary. The patients in the laryngoscope study were all reexamined after the initial adjustment and most adjustments needed over a period of two to four weeks.

“We recommend a custom device made by a dentist,” said Dr. Benjamin. “And you should be retested to see how well it works. There are subjective and objective improvements that should be pursued. “

But there are people for whom neither CPAP nor dental devices work, either because they cannot use them consistently and correctly, or because the devices themselves do not solve the problem if they are used correctly. Various effective surgical procedures exist for these patients.

The most common is soft tissue surgery, which involves modifying or removing tissue from the back of the mouth. Depending on the structures and muscles of the mouth, the surgeon can trim the soft palate and uvula, remove the tonsils, shrink tissue with a heated instrument, straighten a crooked septum or change the position of the tongue muscles – all with the aim of improving airflow.

There are also bone surgeries that move the jaw forward to increase the total breathing space, a procedure that can involve a lengthy recovery period.

In 2014, the Food and Drug Administration approved a device called the Inspire Upper Airway Stimulation. This is a small device that is implanted under the skin like a pacemaker. Using two electrical wires, it detects the breathing pattern and stimulates the nerve that controls the tongue to move it out of the way and allow the air to flow freely. Implantation is a daily surgical procedure that takes about two hours.

“It doesn’t change the anatomy, and recovery is easier than with other surgeries,” said Dr. Maria V. Suurna, Associate Professor of Otorhinolaryngology at Weill Cornell Medicine, who specializes in sleep apnea surgery. “It’s effective. It has the lowest complication rate of any surgery.

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Business

Creating Asia’s first whole-plant primarily based various meat model

The appetite for alternative meat is growing worldwide.

With increasing awareness of the nutritional and environmental effects of meat consumption, producers and consumers are looking for various sources to meet the continuing demand for protein.

One of them is Dan Riegler, whose evolving relationship with meat inspired him to co-found Karana.

“I’ve been a vegan skeptic, a carnivore for much of my life, and I’ve taken a big turn,” Riegler told CNBC Make It.

A meat alternative for Asia

Karana is the food start-up in Singapore that is positioning itself as Asia’s first plant-based meat brand. The flagship – a substitute for pulled pork – is made entirely from jackfruit, oil, and salt, with no processed ingredients or preservatives.

Started in 2018 when the demand for meat alternatives increased, Riegler saw a market niche for meat substitute products that were specially developed for Asian cuisine.

We saw a great need to identify products with more local applications for APAC.

And Riegler

Co-founder Karana

“We saw a great need to identify products with more local applications for APAC,” said Riegler, now 35, who built a career in agricultural supply chains across Southeast Asia.

“Pork is the number one meat consumed in this region and we haven’t seen many products there that are really tailored to a need.”

Asia is responsible for producing and consuming half of the world’s pork.

CNBC

In fact, half of the world’s pork is produced and consumed in Asia, with most of that demand coming from China.

So Riegler and his co-founder Blair Crichton, formerly Impossible Foods, which also produces plant-based meat alternatives, set out to find an environmentally friendly alternative.

Creating Pork from Jack All

It wasn’t long before the couple identified Karana’s first product: a jackfruit pork substitute sourced from smallholders in Sri Lanka.

Jackfruit has a long history in South and Southeast Asian cuisine, especially in vegetarian and vegan dishes. The unripe young jackfruit is known for its tightly packed, fibrous texture and meat-like properties. It is widely used in savory foods, while the sweet ripe jackfruit is consumed raw.

Jackfruit is widely used in many South and Southeast Asian dishes.

CNBC

“Jackfruit as a harvest does not need irrigation, does not need pesticides, does not need herbicides. So it is a very robust tree, and when it bears fruit, it is very, very productive,” said Carsten Carstens, scientific director of Karana and first hire.

In fact, there are so many jackfruit in the region that tons of them are wasted every year. This is due in part to the complexity of the preparation and cooking.

We knew jackfruit was not reaching its potential.

And Riegler

Co-founder Karana

“The formats it was available in … just weren’t exciting to us. They were very difficult to work with, they didn’t give interesting textures and end results, and we knew jackfruit was not reaching its potential.” Said Riegler.

So the founders set about adapting the fruit for a mass market – and soon developed a chemical-free, mechanical process at their Singapore manufacturing facility to convert the fruit into a shredded, meat-like product that is easy for cooks and consumers to use.

“Our intention was really to create something that chefs can use to create fantastic dishes,” said Carstens. “It’s just too labor-intensive for the modern kitchen in a modern establishment (food and beverages).”

Opening up a growing market

Karana’s invention whets the appetite for more ethical and sustainable foods growing across Asia and beyond.

Even before the pandemic, the alternative meat market was estimated at $ 140 billion, or 10% of the world’s meat industry, within a decade.

The alternative meat industry is estimated to be worth $ 140 billion by 2029.

Barclays

Mirte Gosker, acting executive director of the Good Food Institute in Asia Pacific, said the demand for meat substitutes in Asia is increasing as awareness of food safety and nutrition increases.

“Here in Asia we see a real demand for healthy products with high nutritional value,” said Gosker. “And especially in China, one of the reasons people buy plant-based meat, actually the biggest reason, is a desire to lose weight.”

Animal husbandry is currently making the largest two or three contributions to the most pressing environmental challenges on our planet.

Myrtle Gosker

Acting Managing Director of the Good Food Institute Asia Pacific

In addition, the environmental impact of traditional animal husbandry is no longer sustainable.

“Animal husbandry is currently making the largest two or three contributions to the most pressing environmental challenges on our planet. These include air pollution, water pollution, water scarcity and loss of biodiversity,” said Gosker.

“If we didn’t use these fields to grow animal feed, we could actually use these fields for reforestation, to create greater biodiversity or, for example, for renewable energies,” she added.

Whet the appetite of investors

The investment community also sees the benefits of alternative proteins. Global investment in alternative proteins increased 300% in 2020 alone, according to the Asia-Pacific Good Food Institute.

In July 2020, Karana raised $ 1.7 million in seed capital from investors such as Big Idea Ventures, a plant-based food fund backed by Singapore state-owned investment company Temasek and US meat company Tyson Foods.

Karana’s flagship product is a pulled pork substitute made entirely from jackfruit, oil, and salt.

Karana

The investment fueled the company’s 2021 debut in Singapore, where the whole plant’s pork is now available and counted in nine restaurants – from dumplings to “ngoh hiang,” a local pork bun.

Next up is the Hong Kong launch as well as the launch of a range of ready-to-cook retail products. In the meantime, Karana will be able to continue experimenting with jackfruit and other whole plant meat substitutes by investing in a new innovation laboratory.

The more good products there are, the more consumers will increasingly switch to herbal products.

And Riegler

Co-founder Karana

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Health

A Colonoscopy Different Comes House

The task force has found several types of screening tests effective, but the ones most commonly used for those at moderate risk are colonoscopy at a recommended 10-year interval, or FIT annually.

A more recent entry, a home test sold under the brand name Cologuard that detects blood and cancer biomarkers in stool, can be used every three years. However, one study found it to be less effective than most other methods and far more expensive than FIT.

How can FIT compete against colonoscopy when screening is recommended?

Patients at higher risk – including those with colon cancer or parents or siblings with colon cancer, patients with inflammatory bowel disease such as Crohn’s disease, and those with abnormal previous tests, including multiple or large polyps – should get a colonoscopy. often on an accelerated schedule. The method includes inserting a viewing instrument through the anus to directly view the colon of an anesthetized patient.

A colonoscopy has one key benefit: if the gastroenterologist detects polyps that can become cancerous over time (although most don’t), they can be removed immediately. “You prevent cancer by cutting out the things that could lead to cancer,” said Dr. Goodwin. After a negative colonoscopy, patients do not need another for a decade.

However, the complications of the procedure increase with age, although they remain minor. The most serious, a perforated colon, requires hospitalization. Cleansing the bowel the day before the procedure in preparation is bothersome and uncomfortable, and Dr. Goodwin notes that elderly patients sometimes have cycles of diarrhea and constipation for weeks.

Rural residents may have difficulty traveling to an establishment. The use of anesthesia means that every patient needs someone to drive or accompany them home. The prospect of spending two to four hours in a facility, even if one has strict security measures in place, will cause some older adults to postpone testing over concerns about Covid-19.

FIT, which is much more widely used in other countries, avoids many of these difficulties. This is a significant improvement over previous home stool exams. It requires a one day sample instead of three and is not subject to any food or drug restrictions. A positive result still requires a colonoscopy, but the vast majority of patients avoid this result.

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Entertainment

‘Comfortable Face’ Assessment: Various Remedy

“Happy Face” is a defiant, generically unclassifiable film that dares viewers to question its sensitivity. The focus is on a 19 year old named Stan (Robin L’Houmeau) who wraps gauze around his head and joins a support group for people with atypical facial appearances. When the enforcement exercises suggested by group leader Vanessa (Debbie Lynch-White) don’t do much good, Stan takes command and shows his new friends that cognitive behavioral therapy is nowhere near as cathartic as dumping trash in a gaping restaurant patron. Stan’s vision for the cohort is a cross between an intrusive version of the talk cure and a fighting club.

In Montreal, Happy Face stars as Alison Midstokke, who has a rare disease that affects the bones and tissues of the face. She plays a hand-held model with full-body shots in its sights, and ER Ruiz as a police officer whose appearance has changed as a result of a car accident during a chase. They project nuanced, charismatic mixtures of confidence and wounded pride. But is it problematic to make a movie in which they need an implausible cheater to lead them to personal breakthroughs using character building lessons derived from Dungeons & Dragons?

The director Alexandre Franchi, who wrote the script with Joëlle Bourjolly, safeguards himself against this accusation by drawing a tense comparison between Stan and Don Quixote and presenting Stan himself with unsolved challenges. (His mother, played by Noémie Kocher, with whom he is worryingly close – she is shown scrubbing him in the bathtub – dies of multiple brain tumors.)

“Happy Face” dares to be distinctive, and that’s something even if the demeanor – especially Stan’s – isn’t always convincing.

Happy face
Not rated. Running time: 1 hour 40 minutes. Watch virtual cinemas.

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Business

How baseball playing cards turned one million greenback different funding

Packs of 2019 Topps cards spread out on a table.

Sam Rega

Interest in collecting and in values ​​has grown steadily over the past decade, and prices went up really faster sometime around 2016 or 2017. With the outbreak of the pandemic earlier this year, card collecting reached new heights. These individuals were largely driven by people in their thirties and forties collecting at a young age and were at home revisiting their card collections.

Then came ESPN’s release of the Michael Jordan documentary series “The Last Dance”. Auction houses and eBay saw an increase in Michael Jordan cards and memorabilia, followed by even greater interest in basketball cards and beyond.

“It brought back nostalgia. It brought back memories of the greatness of Michael Jordan, and his maps and memorabilia grew. And in our industry, it’s definitely one case where rising tides raise all boats,” said Ken Goldin, Founder and CEO of Goldin Auctions said CNBC.

A 15 card pack of Panini Chronicles basketball tickets for the 2019-2020 period.

Sam Rega

As sports cards increase in value, many collectors collect high value collections as part of a diversified investment portfolio. What sets this era apart from the previous one is the recognition that these cards are a legitimate alternative good. Alt, a Silicon Valley startup founded by Leore Avidar, aims to create clarity and security for alternative assets, especially sports cards.

Collectors and investors see a bright future for sports cards. Card companies are aware of their past mistakes and collectors have more information than ever before. If growth continues, Leore Avidar expects records to continue to be broken.

“I’ll say we’ll see our first $ 10 million card in the next two years,” Avidar says.

Check out the video above to find out why sports cards are a popular alternative.