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Health

A U.N. Declaration on Ending AIDS Ought to Have Been Simple. It Wasn’t.

The United Nations on Tuesday adopted new targets for ending AIDS as a public health threat by 2030, a target that most countries could seemingly easily agree to. But consensus was elusive.

In early negotiations on what is known as the Political Declaration, the United States and the European Union fought to outlaw policies and laws that stigmatize or even criminalize high-risk groups – and drastically scaled back measures to relax patent protection for HIV drugs .

The UN Declaration sets priorities for the global fight against AIDS and guides national policy. There are also opportunities for global health groups and civil society organizations to put pressure on governments to honor their commitments.

After several days of intensive work by delegates from some countries and skilful negotiations by others, the member countries adopted a final version of the declaration on Tuesday morning. The final draft includes an important new goal of having most nations reform discriminatory laws so that less than 10 percent of the world’s countries would take action that unfairly targets people at risk of or living with HIV

“These laws drive the most severely affected by HIV away from HIV prevention and treatment,” said Matthew Kavanagh, director of the Global Health Policy and Politics Initiative at Georgetown University. “This could be a vital tool to get the world back on track to end AIDS.”

On Monday, Dr. Kavanagh and colleagues have a new piece of work showing that countries that criminalize same-sex relationships, drug use, and sex work have had far less success in fighting HIV

But the declaration does not move the needle to patent protection. The United States was among the nations whose delegates significantly watered down or shortened the language to relax patents to provide better access to affordable HIV medicines in low and middle income countries, an attitude endorsed by the Biden government directly contradicted patent waiver for Covid vaccines.

“The mixed messages from the government in the face of recent support for the waiver of Covid-19 vaccine patents are confusing and disappointing,” said Annette Gaudino, director of policy at the Treatment Action Group, an advocacy group in New York. “This would by far not be the first time the US has put drug company profits above people and public health.”

The UN brings together heads of state, health ministers and non-governmental organizations to set priorities for the fight against the HIV pandemic every five years. At a similar meeting in 2016, member countries agreed to aim for less than 500,000 new HIV infections per year, less than 500,000 AIDS-related deaths and the eradication of HIV-related discrimination by 2020.

The world did not achieve these goals: in 2020 around 1.5 million people became infected with HIV and around 690,000 died.

Ending AIDS by 2030 was an ambitious goal adopted by the UN in 2015 as part of a broader agenda for sustainable development. But without more advanced policies and laws, the goal is not achievable, said Dr. Kavanagh.

“To end AIDS by 2030, governments must commit to taking a people-centered, rights-based approach to HIV, working on policy and legal reform, engaging and supporting communities, and ending inequalities,” said Winnie Byanyima, Executive Director from executive UNAIDS said in an email statement.

The original draft of the April 28 statement included a commitment to end “criminal laws, policies and practices, stigma and discrimination based on HIV status, sexual orientation and gender identity.”

Delegates from a few countries, including the Africa Group, China, Russia and Iran, tried to erase allusions to sexual or gender identity or to sex education for girls. This has only partially succeeded: the current text calls for prevention approaches that are tailored to risk groups, including sex workers, men who have sex with men, drug users and transgender people.

Delegates from African countries have successfully inserted a language in which they reaffirm “the sovereign rights of member states” and emphasize that the commitments in the declaration would be implemented “in accordance with national laws, national development priorities and international human rights”. About half of the countries where homosexuality is illegal are in Africa.

The declaration in its current form also calls on countries to “empower women and girls to take care of their sexual and reproductive health and reproductive rights,” a section that Saudi Arabia, Russia and the Holy See attempted remove the text.

Representatives from Belarus, China and Russia also deleted a section calling on member countries to recognize citizens’ autonomy in matters of sexuality; its replaced text encouraged “responsible sexual behavior, including abstinence and fidelity”. The final document has been reverted to the original text.

Including language through high-risk groups is critical to success, some experts said. Gays and other men who have sex with men, people who inject drugs, and female sex workers are almost 30 times more likely to have HIV than the general population.

If these groups don’t have access to preventive therapy, clean needles, condoms, or education, “we will undermine the possibility of actually ending AIDS by 2030,” said Eric Sawyer, an advocate for people living with HIV and long-term survivors.

An early draft of the declaration also contained a longer section aimed at relaxing patent protection. Under the current global rules, only the 50 least developed countries are allowed to delete patents on pharmaceutical products in order to distribute them to citizens.

The draft called for “an indefinite moratorium on international intellectual property regulations for drugs, diagnostics and other health technologies”. Representatives from the United States and Switzerland deleted this section. A representative from the European Union said: “This is not the place to discuss these general issues.”

The United States also added language to the reduced version to recognize the “importance of the intellectual property rights regime in contributing to a more effective AIDS response.”

Activists said an anti-patent waiver stance was perfectly consistent for the European Union, which also spoke out against waiving patents on Covid vaccines. Vaccine manufacturers have argued that patent protection is essential to fuel innovation.

Citing the urgent need for vaccines, however, Biden government officials have said they would support a patent waiver that would allow companies to manufacture cheaper versions of the vaccines for the rest of the world.

Given this trend, “it would be really inconsistent” for the US to oppose a relaxation of patent protection for HIV drugs, said Brook Baker, law professor at Northeastern University and senior policy analyst with the Health Global Access Project, an advocacy group.

“Why in the world should the US be talking on a seemingly almost identical subject from two sides of the mouth?”

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Health

Ganga Stone, Who Gave Sustenance to AIDS Sufferers, Dies at 79

Ganga Stone, who survived on odd jobs in Manhattan until she discovered that her life’s mission was to bring free homemade meals to bedridden AIDS patients on her bicycle, then expanded her volunteer corps of cooks and couriers into an enduring organization called God’s Love We Deliver, died on Wednesday in Saratoga Springs, N.Y. She was 79.

Her death, at a health care facility, was confirmed by her daughter, Hedley Stone. She said a cause had not been determined.

In 1985, Ms. Stone was selling coffee from a cart on Wall Street and feeling unfulfilled. She came to the conclusion, she later told The New York Times, that “if my life were not useful to God in some direct way, I didn’t see the point in living it.”

But while volunteering at the Cabrini Hospice on the Lower East Side, she had an epiphany. She was asked to deliver a bag of groceries to Richard Sale, a 32-year-old actor who was dying of AIDS. When she realized that he was too weak to cook, she rounded up friends, who agreed to bring him hot meals.

“I had never seen anyone look that bad,” she recalled. “He was starving, and he was terrified.”

Legend has it that when she returned to the neighborhood with food tailored to Mr. Sale’s nutritional needs, she ran into a minister, who recognized her. When she told him what she was doing, he replied: “You’re not just delivering food. You’re delivering God’s love.” (In another version of the origin story, Ms. Stone said she was brushing her teeth when she envisioned “We Deliver” signs on restaurant storefronts.)

“It’s the perfect thing — it’s so nonsectarian it’s impossible to misunderstand,” she told The New Yorker in 1991.

The fledgling organization — made up of Ms. Stone and a few friends, including her roommate, Jane Ellen Best, with whom she founded the organization — began by delivering meals, home-cooked or donated by restaurants, to mostly gay men who were too incapacitated by a then-mysterious disease to shop or cook. They left their orders on her answering machine.

Not everyone wanted a gourmet meal.

“One guy wanted a can of Cheez Whiz and saltines,” Ms. Stone said.

In the first year alone, 400 of their clients died.

As the epidemic spread, the group attracted publicity and support from religious groups, government agencies and celebrities. (Blaine Trump, the former wife of former President Donald J. Trump’s brother Robert, is the vice-chairwoman.)

This year, God’s Love We Deliver, with a budget of $23 million, hopes to distribute 2.5 million meals to 10,000 people in the New York metropolitan area who are homebound with various diseases.

Ingrid Hedley Stone was born on Oct. 30, 1941, in Manhattan and raised in Long Island City, Queens, and the Bronx. Her father, M. Hedley Stone, a Jewish immigrant from Warsaw who was born Moishe Stein, was a Marxist who was an organizer for the National Maritime Union and later its treasurer.

Her mother, Winifred (Carlson) Stone, a daughter of Norwegian immigrants, was a librarian (she established the library for the National Council on Aging), who suffered from Lou Gehrig’s disease when Ms. Stone was in her mid 20s.

A graduate of the Fieldston School in the Bronx, Ms. Stone studied comparative literature at Carleton College in Minnesota and attended Columbia University’s School of General Studies, but never graduated.

Her eclectic résumé of jobs included driving a cab and working as a morgue technician. She was hired as a waitress at the Manhattan nightclub Max’s Kansas City, where she met Gerard Hill, an Australian busboy. They married in 1970, but she left the marriage after 13 months, and the couple divorced in 1973.

In addition to her daughter, her survivors include a son from that marriage, Clement Hill, and a sister, Dr. Elsa Stone.

A self-described radical feminist, Ms. Stone was steered by her yoga instructor to the spiritual teachings of Swami Muktananda. In the mid-1970s, after sending her 6-year-old son to live with his father, she embarked on a two-year retreat to the swami’s ashram in Ganeshpuri, India. She cleaned laundry, washed floors and went nine months without speaking. The swami named her Ganga, for the Ganges River.

When she returned to New York, Ms. Stone resumed her composite career until the mid-1980s, when she was inspired to start God’s Love.

She retired as the organization’s executive director in 1995 and was succeeded by Kathy Spahn. The next year, Ms. Stone, who taught courses about dying, published “Start the Conversation: The Book About Death You Were Hoping to Find.” She lived in Saratoga Springs.

“I’ve always been attracted to working with dying people, since it seems to me that there’s no more important moment in a human life than that one,” Ms. Stone told The New Yorker. “Everything else can go badly, but if that moment goes well, it seems to make a difference, and I wanted to make a difference in those moments for people.”

She added, “My sense of my own role in life was to share with people what I know about the deathless nature of the human self, but you can’t comfort people who haven’t eaten.”

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Politics

Former Trump lawyer Michael Cohen aids DA Vance felony probe

Michael Cohen, former attorney for President Donald Trump, testifies before the House Oversight Committee in the Rayburn House Office Building in Washington, DC on Wednesday, February 27, 2019.

Matt McClain | The Washington Post | Getty Images

Senior officials in the Manhattan Attorney’s Office this week asked ex-President Donald Trump’s former personal attorney Michael Cohen to return for his eighth interview with the firm, which is conducting a far-reaching criminal investigation related to the Trump Organization.

One person familiar with the case said that when Cohen was interviewed for the seventh time by officials via videoconference earlier this week, he was asked to be available for a face-to-face interview at DA Cyrus Vance Jr.’s office soon.

Cohen, who is now an avowed enemy of Trump, agreed, the person said.

Cohen declined to speak to CNBC, as did Vance’s spokesman Danny Frost. A Trump Organization spokeswoman did not immediately respond to a request for comment.

The interest in speaking to Cohen repeatedly comes because Vance has strengthened its investigative team, recently gained access to Trump’s financial records, and reportedly broadened the scope of his investigation to investigate Trump’s longtime CFO Allen Weisselberg and the Sons of Weisselberg.

One of these sons works for the Trump Organization and runs the company’s Central Park ice rinks. The other works for Ladder Capital Finance, which has borrowed Trump’s company nearly $ 300 million in connection with four buildings in Manhattan. Vance is known to watch the Trump organization rate its buildings.

These developments, as well as Vance’s long-awaited announcement on Friday that he will not seek re-election this fall, have sparked speculation that the prosecutor will attempt to indict Trump or officials at his company in the coming months.

Vance’s investigation originally focused on how the Trump organization recorded hush money payments made or facilitated by Cohen, prior to the 2016 presidential election, to two women, porn star Stormy Daniels and playboy model Karen McDougal.

When Cohen pleaded guilty to financial financing violations and other crimes in 2018, he told a federal judge that he arranged these payments on Trump’s orders to calmly approve the women over their allegations of having sex with Trump hold. The former president denies the women’s claims.

Cohen later testified to Congress that the Trump Organization would inflate and deflate the value of real estate assets to either gain favorable loan and insurance terms or to reduce the amount of taxes owed on them.

These Cohen allegations are now being investigated in both Vance’s investigation and a civil investigation by Attorney General Letitia James.

Vance court records suggest that his investigation is investigating possible “insurance and banking fraud by the Trump organization and its officials” and possible tax crimes.

Vance last month hired Mark Pomerantz, a private practice criminal defense attorney, as a special assistant prosecutor to work solely on the Trump investigation.

Pomerantz’s career included a stint as head of the criminal justice department of the US Attorney’s Office in Manhattan, where he was responsible for securities fraud and organized crime cases.

Pomerantz was one of the investigators who spoke to Cohen about the video call this week, along with Vance and other top officials in the office, NBC News reported.

The DA office also kept the consulting firm FTI to analyze Trump’s financial records.

In February, shortly after Pomerantz was hired, the US Supreme Court rejected Trump’s efforts to prevent Vance from obtaining his tax returns and other financial records from his longtime accountants through a grand jury subpoena.

The investigators received these documents immediately.

Cohen began working with Vance’s investigation in 2018 before being sentenced to three years in prison for his crimes in 2019.

Investigators from the district attorney’s office visited him at federal prison in Otisville, New York.

Cohen was released from prison last May on fear of being particularly vulnerable to Covid-19 due to several health problems.

He was thrown back in jail in July after defying demands from federal probation officers not to publish a book about Trump or anyone else while he was serving the remainder of his sentence.

About two weeks later, Cohen was released again after an outraged federal judge declared that he had been the victim of retaliation by the Bureau of Prisons for failing to meet this condition. Cohen later published his book on Trump called “Disloyal”.

Since then, Cohen has not only moderated the investigation with Vance, but also hosts a podcast, Mea Culpa, whose guests include other Trump critics such as Daniels and Rosie O’Donnell.

Audio Up, which produces the podcast, touted it Friday as “the fastest growing podcast in the world” with “5 million downloads”.

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Health

David Katzenstein, AIDS Researcher With Deal with Africa, Dies at 69

This obituary is part of a series about people who died from the coronavirus pandemic. Read about others here.

Dr. David Katzenstein was perhaps a dreamer, “with sometimes brilliant and sometimes a little aloof ideas,” said a colleague recently. But from the start he was in a biosphere that spawned new undiscovered and casual killers, not an ivory tower researcher looking at the world through a microscope.

After studying medicine, he did an internship at the University of New Mexico, where his work with indigenous peoples became a permanent commitment to helping underserved populations prevent and control infectious diseases.

As a virologist and clinician, he has not only contributed to advancing the prevention, diagnosis and treatment of HIV and AIDS for 35 years. He also made these techniques available to middle- and low-income patients in sub-Saharan Africa.

Dr. Katzenstein, professor emeritus of infectious diseases and global health at Stanford Medicine, California, died on January 25 in Harare, Zimbabwe, where he had moved after retiring in 2016. He was 69 years old. The cause was Covid-19, said his stepdaughter Melissa Sanders-Self.

“Imbued with a passionate belief in social justice, David Katzenstein had an overwhelming influence on the fight against HIV in sub-Saharan Africa,” said Dr. Lloyd Minor, dean of Stanford University medical school, in a statement.

David Allenberg Katzenstein was born on January 3, 1952 in Hartford, Connecticut, to physicist Henry Katzenstein and clinical psychologist Constance (Allenberg) Katzenstein.

He graduated from the University of California at San Diego in 1973 with a bachelor’s degree in biology and received a medical degree there in 1977.

He married Sharon Mayes, who died in 2007. In addition to his stepdaughter, his sisters Ruth Souza and Amy Harrington survive him. his brother Rob Katzenstein; two bootlegs; and a step great-granddaughter.

After his stay in San Diego, Dr. Katzenstein at the University of California at Davis and the University of Minnesota until 1986.

While at the University of California, the International Antiviral Society-USA said he established a relationship with the Department of Medical Microbiology at the University of Zimbabwe Medical School and became “one of the first US-based HIV researchers to do the committed to work in this region around the world. “

From 1987 to 1989, Dr. Katzenstein as Senior Research Fellow at the Center for Biologics Evaluation and Research of the Food and Drug Administration.

In 1989, he moved to Stanford Faculty as Assistant Clinical Professor of Infectious Diseases and was appointed Assistant Medical Director of Stanford’s AIDS Clinical Trial Unit, which, among other things, conducted clinical trials of antiretroviral drugs that prolong the lives of people with HIV

He focused on the challenges posed by resistance to HIV antiviral drugs and was one of the first researchers to publicize the problem in Africa.

In Zimbabwe, he directed the Institute of Biomedical Research and Education in Harare, where he trained clinical researchers, introduced advanced diagnostic and monitoring techniques into community health programs, and continued to publish research studies until his death.

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Health

Listening to Aids Might Use Some Assist

But Dr. Lin said, “Most of what you see out there – ’50 dollar wonder device! ‘ – is complete rubbish. People can’t tell who to trust. “

However, once the state requirements for over-the-counter hearing aids are established, manufacturers of high-quality PSAPs can apply for approval. “All other PSAPs will fall by the wayside,” said Dr. Lin. If their labels say they’re not FDA approved, “Nobody is going to buy them, and they shouldn’t.”

In the face of a huge and underserved market, consumer electronics companies (allegedly Apple and Samsung) as well as startups stand ready. “There’s a lot of venture capital into hearing technology once the barriers come down,” said Dr. Rathi.

Bose acted early and received FDA approval in 2018 for its Hearphone, which the buyer could set with a smartphone app. But without the new rule, government restrictions would have prevented national sales so Bose wouldn’t market them.

However, the company is working on a new over the counter product. “We are cautiously optimistic that 2021 will be the year,” said Brian Maguire, director of the Bose Hear Group.

Once the FDA takes action and companies and retailers ramp up, expect new products and advertisements to appear in stores and online. “We’re going to have some Wild West time,” said Ms. Kelley. “People will be confused. You will need a lot of information. “

From this point onwards, audiologists will no longer act as exclusive gatekeepers for hearing aids. But they can still provide important services: testing, education and advice, adapting devices – even if customers bought them elsewhere.