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Small Examine Seems at Kids With Covid Inflammatory Syndrome

Dr. Newburger, who was not involved in the UK report, called it a “small but important study” that “adds new information to the knowledge gap about the long-term effects of MIS-C”.

They and the authors themselves noted that the results were limited because the children in the study were not compared with a control group of children without MIS-C or those with other diseases. For example, it is unclear whether her emotional problems and muscle weakness were the result of the syndrome, the process of being hospitalized for an illness, or other stressors during that time. “Mental health and physical condition affected children and adolescents in general during the pandemic,” said Dr. Newburger.

Dr. Srinivas Murthy, an associate professor of pediatrics at the University of British Columbia who was not involved in the new study, said it may be difficult to figure out which residual problems were directly due to the syndrome and which could result from critical illness. He said the fact that some of the children still had problems with muscle weakness and stamina could bring important lessons as such problems may require different types of care, including “post-hospital rehabilitation options.”

Dr. Penner said the Great Ormond Street Hospital team had made changes to the way they treat children hospitalized with the syndrome since the fall because they recognized “how badly their muscles are initially affected and how much they are tired and these children are weakened. “

In the hospital, for example, “it is extremely difficult for these children to just go from bed to the bathroom,” he said.

The hospital is now more focused on providing hospitalized physiotherapy and working with musculoskeletal therapists to the children, sending them home with a customized rehabilitation plan linked to an app.

“We also involved our occupational therapists and developed a once-a-month fatigue program where parents dial in for a group session,” said Dr. Jerk. “I think the main message we are giving them is to avoid this boom-and-bust cycle where the kids try to do the things they used to do at full speed and then kind of crash afterwards – as opposed to a gradual increase in activity back to its normal state. “

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Provide chains could return to China amid Covid resurgence in India, Vietnam

The Covid-19 resurgence in some parts of Asia could lead to a change in fortunes for China, according to an economist.

Previously, the U.S.-China trade war caused companies to move their supply chains out of China, shifting their production and distribution networks for products and services. As a result, countries like Vietnam and India benefited as companies moved to set up shop in their countries.

But the situation appears to be changing, and supply chains could pivot back to China as cases spike in India and Vietnam, according to Zhang Zhiwei, chief economist at Pinpoint Asset Management.

Read more about China from CNBC Pro

“Before the pandemic, we saw factories moving out of China — Samsung, Foxconn these big name companies — setting up factories in Vietnam, India,” he told CNBC’s “Street Signs Asia” on Monday.

The spike in cases in those two countries has forced factories owned by Taiwanese contract manufacturer Foxconn, a major Apple supplier, to shut down facilities in India and Vietnam, he said.

“This could put the relocation of supply chains on hold for quite some time. The key issue here is that international travel is suspended, so multinational companies can’t send their staff to India and Vietnam to set up new factories,” Zhang added.

Cases in India surged to record-breaking highs in April and shows little signs of abating significantly —economists have predicted the South Asian economy will likely contract this quarter.

In Vietnam, the northern province of Bac Giang on Tuesday ordered four industrial parks — including three that house production facilities of Taiwan’s Foxconn — to temporarily shut down due to an outbreak of Covid-19.

The situation could benefit China, Zhang suggested. However, he pointed out that the extent of how much China could stand to gain will depend on how long the situation in India and Vietnam continues for.

Right now, export growth in China is between 20% to 40% a month, he said. If the factories in India and Vietnam return to production very soon, China’s exports would be expected to slow down in the second half of the year as companies move their manufacturing to those two countries.

“But if supply chain (in India and Vietnam) is disrupted for a long time, we could see this kind of 20%, 30% export growth (in China) to continue into next year,” Zhang said.

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Kids With Covid Inflammatory Syndrome Might Overcome Their Most Critical Signs

Dr. Newburger, who was not involved in the UK report, called it a “small but important study” that “adds new information to the knowledge gap about the long-term effects of MIS-C”.

They and the authors themselves noted that the results were limited because the children in the study were not compared with a control group of children without MIS-C or those with other diseases. For example, it is unclear whether her emotional problems and muscle weakness were the result of the syndrome, the process of being hospitalized for an illness, or other stressors during that time. “Mental health and physical condition affected children and adolescents in general during the pandemic,” said Dr. Newburger.

Dr. Srinivas Murthy, an associate professor of pediatrics at the University of British Columbia who was not involved in the new study, said it may be difficult to figure out which residual problems were directly due to the syndrome and which could result from critical illness. He said the fact that some of the children still had problems with muscle weakness and stamina could bring important lessons as such problems may require different types of care, including “post-hospital rehabilitation options.”

Dr. Penner said the Great Ormond Street Hospital team had made changes to the way they treat children hospitalized with the syndrome since the fall because they recognized “how badly their muscles are initially affected and how much they are tired and these children are weakened. “

In the hospital, for example, “it is extremely difficult for these children to just go from bed to the bathroom,” he said.

The hospital is now more focused on providing hospitalized physiotherapy and working with musculoskeletal therapists to the children, sending them home with a customized rehabilitation plan linked to an app.

“We also involved our occupational therapists and developed a once-a-month fatigue program where parents dial in for a group session,” said Dr. Jerk. “I think the main message we are giving them is to avoid this boom-and-bust cycle where the kids try to do the things they used to do at full speed and then kind of crash afterwards – as opposed to a gradual increase in activity back to its normal state. “

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NY Covid vaccine charges plummet as states roll out extra freebies for pictures

Naomi Hassebroek receives her second COVID-19 vaccine at NYC Health+Hospitals Gotham Health Sydenham, in the Manhattan borough of New York City, New York, March 29, 2021.

Caitlin Ochs | Reuters

New York’s Covid-19 vaccination rate has declined dramatically in recent days, Gov. Andrew Cuomo said Monday as he pleaded with residents to get immunized against the disease that’s claimed more than 590,000 lives in America.

The state administered just 63,000 vaccines in the last 24 hours, with a seven-day average of about 133,000 shots administered in the past week as of May 24, according to state data.

The current seven-day average is a small increase from last week’s but a sharp drop from the state’s peak when it reported a seven-day average of about 266,000 vaccinations on April 4.

Cuomo urged New Yorkers to take vaccines seriously, saying the coronavirus pandemic is still a cause for caution.

“It’s not over, it’s managed, but it’s not over,” Cuomo said at a press briefing. “The number of vaccinations is dropping off dramatically, we’re now doing fewer than 100,000 per day — that’s a dramatic decline, 55% decline in how many vaccines we’re doing.”

Data from the Centers for Disease Control and Prevention shows the U.S. is reporting an average of 1.8 million vaccinations per day over the past week. About 49% of the U.S. population has had at least one shot with 39% fully vaccinated.

The nationwide seven-day average for reported administered vaccines is currently 1.7 million, down from a peak seven-day immunization average of 3.4 million reported on April 13.

The slowing immunization rate has public officials like Cuomo and New York City Mayor Bill de Blasio offering different perks to convince reluctant people to get their vaccine shots. They’ve previously offered free Yankees tickets, “vax & scratch” lottery tickets, free subway and railroad rides, and tickets to popular attractions like zoos and gardens and more.

State parks will now be offering free passes with access to any of New York’s 16 state parks to anyone who gets the vaccine this week at a state park vaccination site, a campaign Cuomo dubbed “a shot in the park.”

Cuomo said he’s targeting the “youthful and the doubtful” with the latest round of incentives.

“Enjoy the park, come get a vaccine, we’re going to set up a vaccine site at everyone of the 16 state parks,” he said.

Maryland, Ohio and Oregon have set up vaccine lotteries to increase declining vaccination rates.

In Ohio, where vaccination rates were falling, the number of people 16 and older getting the shots jumped 28% the weekend after the state announced its vaccine lottery program. Ohio also announced that it would give five full college scholarships to randomly chosen vaccinated students.

New Jersey is offering anyone who gets their Covid shot in May a free beer at several local breweries as part of Gov. Phil Murphy’s “shot and a beer” campaign.

Private businesses across the U.S. have also offered incentives to vaccinated patrons like gift cards, free snacks, marijuana, beer and even free tickets to Six Flags in Illinois.

— CNBC’s Nate Rattner contributed to this report.

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Cease Kissing and Snuggling Chickens, C.D.C. Says After Salmonella Outbreak

A salmonella outbreak related to backyard poultry has led U.S. health officials to issue a stern warning: do not kiss or cuddle your ducks and chickens.

163 illnesses and 34 hospital admissions have been reported in 43 states, the Centers for Disease Control and Prevention said last week. North Carolina had the highest number of reported cases at 13, followed by Iowa at 11. About a third of the cases involved children under the age of 5, the agency said.

The true number of those sick is most likely higher as many recover without medical help and not tested for salmonella, according to the CDC.

The likely source of the outbreak is exposure to backyard poultry, the agency said.

“Do not kiss or cuddle the birds as it can spread germs in your mouth and make you sick,” the agency said.

This was among the guidelines the CDC offered to people who keep poultry at home, whether they are seasoned owners or building their first backyard pen. You should always wash their hands for 20 seconds after contact with birds or related materials, the agency said, and don’t allow children under the age of 5 to touch the birds.

Emily Shoop, poultry educator at Penn State Extension, said Monday poultry farming is “the fastest growing animal-related hobby in the US.”

The CDC has routinely issued similar guidelines over the years, she said, adding that this is the time of year when hatcheries and feeders sell chicks to people who start herding at home.

“You bring these chickens home, you cuddle them close to your face or you kiss them, and then we see some bugs and a salmonella outbreak,” said Ms. Shoop. “The best way to prevent this from happening is to wash your hands after touching chickens, their dung, eggs, or meat.”

Animals can ingest salmonella from contaminated food or the bacteria can live naturally in their intestines. According to the CDC website, some may even pick up the bacteria from their mothers before they are born.

Raising backyard poultry has become more common in recent years, and some have described the process of rearing chickens as an exercise of inter-species respect.

Chick sales often go up during times of anxiety or economic stress, such as being at home. B. Stock market slumps and presidential election years. At the onset of the coronavirus pandemic in the United States, a combination of unemployment, anxious leisure time for those not struggling with illness, and financial instability led people to panic buying chickens, much like toilet paper. Many were first-time buyers.

Although their intentions may have been good, there were health consequences. By mid-December 2020, there had been more than 1,700 salmonella infections in all 50 states, the CDC said, noting that exposure to backyard poultry was the likely cause of the outbreaks. More than 300 people have been hospitalized and one death has been reported. The number of diseases reported was higher than any previous backyard-related outbreak.

Ms. Shoop said that there is a risk with all types of livestock. “These are not pets, and a lot of people get them confused,” she said. Poultry, she said, is usually kept outside and outside of the food preparation areas.

“If you cuddle them close to your face or mouth, you should probably wash your face and brush your teeth as well to prevent cross-contamination from these birds,” she said. “Chickens are by no means dirty animals, but of course they have a lot of bacteria around their bodies.”

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Two doses of Covid vaccines present safety in opposition to India variant

A healthcare worker holds syringes with the Moderna and Pfizer vaccines against the coronavirus disease (COVID-19) at a vaccination centre, in El Paso, Texas, May 6, 2021.

Jose Luis Gonzalez | Reuters

A new study has found that two doses of either the Pfizer-BioNTech or AstraZeneca-University of Oxford vaccine give effective protection against the Covid variant first discovered in India, however it underscored the need for two doses, as both vaccines were significantly less effective after only one shot.

The study, led by Public Health England, also found that two doses of one of those vaccines were similarly as effective at protecting against the variant that first emerged in the U.K. and has since become a dominant strain in the West.

Dr. Jenny Harries, CEO of the U.K. Health Security Agency, told the BBC that the study provided the “first real-world evidence of vaccine effectiveness” against the variant first identified in India.

Conducted between April and May, the research found that the Pfizer-BioNTech vaccine was 88% effective against symptomatic disease from the B.1.617.2 Covid variant — a subtype of a variant that emerged in India last fall which has since spread to Europe — two weeks after the second dose. The vaccine was 93% effective two weeks after the second dose against the B.1.1.7 variant. which was first discovered in the U.K. last fall.

Meanwhile, two doses of the AstraZeneca vaccine were found to be 60% effective against symptomatic disease from the B.1.617.2 variant from India, compared with 66% effective against the strain from the U.K.

“Vaccine effectiveness against symptomatic disease from the B.1.617.2 variant is similar after 2 doses compared to the B.1.1.7 (Kent) variant dominant in the U.K., and we expect to see even higher levels of effectiveness against hospitalisation and death,” the study authors wrote. The results were published Saturday as a preprint and the study has not yet been peer-reviewed.

PHE said the difference in effectiveness between the vaccines after two doses “may be explained by the fact that rollout of second doses of AstraZeneca was later than for the Pfizer-BioNTech vaccine, and other data on antibody profiles show it takes longer to reach maximum effectiveness with the AstraZeneca vaccine.”

However, both vaccines were only 33% effective against symptomatic disease from B.1.617.2 three weeks after the first dose. In the same time frame, they were found to be 50% effective against the B.1.1.7 variant.

Variant of concern

The variant first discovered in India has been blamed for causing a dramatic third wave of infections in the country, overwhelming hospitals and causing thousands of deaths this spring. There were concerns that Covid vaccines could be rendered less effective by the variant so the latest data should help allay those worries.

The India variant has been detected in numerous other countries now, according to the World Health Organization, which dubbed it a “variant of concern” in early May.

The PHE study analyzed data from 1,054 people, of all age groups and several ethnicities, confirmed as having the B.1.617.2 variant through genomic sequencing. The data was collected from April 5 and hence covers the period since the B.1.617.2 variant (one of three variant subtypes found in India) emerged in parts of the U.K.

“As with other variants, even higher levels of effectiveness are expected against hospitalisation and death. There are currently insufficient cases and follow-up periods to estimate vaccine effectiveness against severe outcomes from the B.1.617.2 variant. PHE will continue to evaluate this over the coming weeks,” the study’s authors added.

Responding to the study, the U.K.’s health secretary, Matt Hancock, described the findings as “groundbreaking – and proves just how valuable our Covid-19 vaccination programme is in protecting the people we love.”

The U.K. has given more than 22 million people two doses of a Covid vaccine, while 72% of the population (or almost 40 million people) have had one shot, government data shows.

Hancock said the latest data emphasized “how important the second dose is to secure the strongest possible protection” against Covid-19 and its variants.

Separate PHE analysis indicated that the country’s Covid-19 vaccination program has so far prevented 13,000 deaths and around 39,100 hospitalizations in older people in England, up to May 9.

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The Perilous Hunt for Coconut Crabs on a Distant Polynesian Island

We meet Adams Maihota in front of his house in the middle of the night. As a crab hunter, he wears white plastic sandals, board shorts, a tank top, and a cummerbund to keep string lengths up. He takes a sprig of wild mint and puts it behind his ear for good luck.

Photographer Eric Guth and I follow Mr. Maihota’s blazing headlights into the forest in search of coconut crabs, locally known as kaveu. The largest terrestrial invertebrates in the world, they are delicious, cooked or fried with coconut milk. Since phosphate mining stopped here in 1966, they have become one of Makatea’s greatest exports.

It’s ankle-breaking terrain. We negotiate the roots of pandanus trees and the infinite Feo, a Polynesian name for the ancient reef rocks that stand tall everywhere. The vegetation hits us in the face and legs, and our skin becomes drenched in sweat.

The traps Mr Maihota set earlier this week are made of notched coconuts tied to trees with fibers from their own shells. When we reach one, we turn off our lights to quietly approach. Then Mr. Maihota throws himself.

A moment later he stands up with a sky-blue crab that kicks its ten legs in wide circles. Even if its fleshy belly curls under the rest of its body, the animal is much longer than the hunter’s hand.

Makatea, part of the Tuamotu Archipelago in French Polynesia, is located in the South Pacific about 150 miles northeast of Tahiti. It is a small raised coral atoll just under four and a half miles in diameter at its widest point with sheer limestone cliffs rising up to 250 feet straight out of the sea.

From 1908 to 1966, Makatea was home to the largest industrial project in French Polynesia: eleven million tons of phosphate-rich sand were excavated and exported for agriculture, pharmaceuticals and ammunition. When mining stopped, the population fell from around 3,000 to less than 100. Today, there are around 80 full-time residents. Most of them live in the central part of the island, near the ruins of the old mining town that is now rotting in the jungle.

A third of Makatea is made up of a maze of more than a million deep, circular holes known as the Extraction Zone – a legacy of mining. Crossing this area, especially at night when coconut crabs are active, can be fatal. Many of the holes are over 30 meters deep and the ledges between them are narrow. Even so, some hunters do it to get to the rich crab habitat on the other side.

One evening before sunset, a hunter named Teiki Ah-scha meets us in a notoriously dangerous area called Le Bureau, named after the mining buildings that used to be there. Mr Ah-scha wears flip-flops and trudges around the holes and balances on their edges. When he chases through the extraction zone, he comes home in the dark with a sack full of crabs on his back.

Mr. Maihota hunted this way too – and he tells me he misses it. However, since his wife fell into a shallow hole a few months before our 2019 visit, she has forbidden him to cross the extraction zone. Instead, he sets traps around the village.

Coconut crabs live in a wide range, from the Seychelles in the Indian Ocean to the Pitcairn Islands in the southern Pacific. They were part of the local diet long before mining. The largest specimens, “les monstres”, can be the length of your arm and live for a century.

There is no population study of Makatea, so the crabs’ conservation status is unclear – although they seem to be everywhere at night when they rattle over the rocks.

If we catch crabs that are not legal – either women or those less than six centimeters above the shell – Mr Maihota lets them go.

If the islanders aren’t careful, the crabs might not be there for future generations. In many locations in the Indo-Pacific, the animals were hunted to extinction or local extinction.

Makatea is at a crossroads. Half a century after the first mining era, a proposal for more phosphate extraction is pending. Although the island’s mayor and other supporters cite the economic benefits of labor and income, opponents say new industrial activity will destroy the island, including its fledgling tourism industry.

“We can’t let her suffer again,” a woman says to me, referring to the island as a living being.

Still, it’s hard to make a living here. “There’s no work,” says Mr. Maihota as we stand under the stars and sweat drips onto the forest floor. He doesn’t want to talk about the mine. The previous month, he shipped 70 coconut crabs to buyers in Tahiti for $ 10 each.

In popular hunting areas, hunters say the crabs are smaller or smaller, but hunters depend on income and no one has a complete picture of how the population as a whole is doing.

The next morning we visit Mr. Maihota’s garden, where the crabs are confiscated in individual boxes so that they do not attack each other. He will feed them coconut and water to cleanse their systems as they eat all kinds of foods in the wild, including carrion.

In daylight, their shells are rainbows of purple, white, orange, and many shades of blue. For now, at least – with no mining and although the crops are still sustainable – they seem perfectly adapted to makatea, holes and everything.

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Instances could have peaked however deaths hit new document

People receive their Covid-19 vaccines from medical workers at a vaccination centre set up in the classroom of a government school on May 04, 2021 in New Delhi, India.

Getty Images | Getty Images News | Getty Images

India reported its highest single-day increase in Covid-19 deaths as cases stayed below 300,000 for the third straight day.

On Wednesday, health ministry data showed at least 4,529 people succumbed to the disease over a 24-hour period as 267,334 new cases were registered.

India has reported more than 25 million cases and over 283,000 deaths so far. But experts suggest the figures undercount the actual toll as testing is limited in some places, particularly in rural areas currently experiencing a surge in cases. Many patients who have died at home — due to hospitals running out of beds — are also typically left out of the official tally.

The South Asian nation has been testing anywhere between 1.5 million to 2 million samples daily over the last seven days, according to government data. The test positivity rate has come down from 19.45% last Thursday to 13.31% on Wednesday as of 8 a.m. local time.

Some have suggested that the second wave may have already reached its peak after daily cases reached a record high of over 414,000 on May 7. But there is growing concern over the pandemic’s spread into rural India, where smaller towns and villages do not have adequate health-care infrastructure to handle a sharp rise in cases that left big metropolitan cities like New Delhi and Mumbai scrambling.

In its newest weekly epidemiological update on the pandemic, the World Health Organization said that all regions reported a decline in new cases apart from the Western Pacific Region last week, where the reported number was similar to the week before.

The South-East Asia region, which includes South Asian and Southeast Asian member states, saw a 12% decline in cases and a 7% increase in death toll last week compared with the previous week. Nepal, which is also facing a Covid crisis, saw an 8% rise in new cases and a 266% jump in the death toll to about 4.2 new fatalities per 100,000 people.

WHO Director-General Tedros Adhanom Ghebreyesus last week urged member countries to continue donating vaccines to the Covax initiative so that it can increase vaccine supply to low-income countries, which are receiving only about 0.3% of global doses.

He pointed out that beyond India, countries like Nepal, Sri Lanka, Vietnam, Cambodia, Thailand and Egypt are also dealing with spikes in cases and hospitalizations.

“Trickle down vaccination is not an effective strategy for fighting a deadly respiratory virus,” he said.

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Uncover a Water Sport – The New York Instances

Sales of kayaks – along with other outdoor gadgets like bicycles and camping gear – soared during the pandemic, so you may have to wait a few months for your boat.

“People are rediscovering how great it is to get outside in their own neighborhood,” said Anton Willis, founder and chief design officer at Oru Kayak, a folding kayak company that has since seen a sales increase of more than 100 percent in 2019 and 2020. “We’re building kayaks as fast as we can. Many other companies are in the same boat, no pun intended. “

Pro tip for new paddlers: “People think they’re going to capsize in the water, but it usually happens if you tip over when you get on or off the boat,” Willis said. “Just start in a flat and undulating spot, like a floating dock or a gentle, sandy beach.”

Sailing has a reputation for being difficult and expensive, but that’s not necessarily the case. “Sailing can be very affordable and accessible. It’s not just for America’s Cup billionaires, ”said Bob Ross, president of the Seattle Sailing Club, which teaches sailing and rents boats to its members. “Yacht clubs have sailing schools for children and adults that are very inexpensive.”

Sailing is about joining a community of other sailors. Get it serious and become part of a racing team, or take it easy and drop anchor in a sheltered harbor for lunch. Most sailors love to share their knowledge and welcome newcomers. You don’t necessarily need experience to work on a larger boat. Check the notice boards or show up at the dock at the local sailing clubs – or try the Go Sailing app – to see if anyone needs a crew member.

“You can sign up as ‘rail meat’ – that’s someone who sits on the rail and weighs the boat down on your heel,” said Michael Campbell, founder of the Universal Sailing Club in Baltimore. “It’s the fastest learning environment you’ll find.”

And you don’t need access to the sea to sail. “There are lakes all over the country and each lake has a small yacht or sailing club that is usually very accessible,” said John Kettlewell, executive director of Sail Martha’s Vineyard, a nonprofit sailing organization in Vineyard Haven, Mass. The yacht club sounds snooty, but usually isn’t. “

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Jury can hear restricted proof of CEO way of life

Theranos founder Elizabeth Holmes leaves the Robert F. Peckham Federal Building with her defense team in downtown San Jose, Calif., on Tuesday, May 4, 2021.

MediaNews Group/The Mercury News via Getty Images | MediaNews Group | Getty Images

Jurors in the trial of Elizabeth Holmes will hear evidence about her extravagant lifestyle as Theranos CEO but with some limitations.

That’s the ruling issued by U.S. District Court Judge Edward Davila late Saturday as part of a 100 page response to motions in Holmes’ upcoming criminal trial.

The judge granted in part Holmes’ motion to exclude evidence referencing her extravagant lifestyle outside of her position as chief executive of the blood-testing start-up.

“The Government may introduce evidence that Holmes enjoyed a lifestyle as Theranos CEO that is comparable to those of other tech company CEOs. This includes salary, travel, celebrity, and other perks and benefits commensurate with the position,” Davila wrote in the filing.

However, “references to specific purchases or details reflecting branding of clothing, hotels, or other personal items is not relevant, and the prejudicial effect of that evidence outweighs any probative value,” the judge added.

The ruling is a partial victory for Holmes as prosecutors cannot introduce details about Holmes’ specific purchases and personal items outside of her position as CEO. Holmes lived in an expensive rental home, traveled by private jet, stayed at luxury hotels and employed Theranos-paid assistants to run her lavish shopping sprees.

“Each time Holmes made an extravagant purchase, it is reasonable to infer that she knew her fraudulent activity allowed her to pay for those items,” Davila wrote. “While the benefits of these purchases are not as directly tied to the fraud…it may still be probative of Holmes’ scienter.”

The ruling comes two weeks after Holmes battled it out with prosecutors in court over whether details of her wealth, lifestyle and perks she attained as CEO would be relevant to jurors in her trial.

At the height of Theranos, the start-up was valued at $9 billion and Holmes was touted as the world’s youngest self-made woman billionaire. The company collapsed in 2018 following a Wall Street Journal investigation that revealed failings in the blood-testing technology.

Davila ruled on more than 20 dueling motions on what jurors can hear in her trial, scheduled to begin on Aug. 30.

A motion by the government to admit business-related text messages between Holmes and her co-defendant Ramesh “Sunny” Balwani was denied by Davila.

Prosecutors say the messages show the two top executives knew how much trouble Theranos was in before it collapsed. In a November 2014 text to Holmes, Balwani describes one Theranos lab as a “f*cking disaster zone,” adding he would “work on fixing this.”

Holmes and Balwani have both pled not guilty to a dozen criminal wire fraud charges in connection with deceiving investors, patients and doctors.