Categories
Business

Britain’s Ports Are Jammed, and Brexit Is Round Nook

“It still works by itself,” said Alex Veitch, general manager of public order for Logistics UK, a trading group.

The problem in the UK was exacerbated by a large shipment of medical masks, gowns, gloves and other equipment ordered for the National Health Service and temporarily stored in Felixstowe. At the end of November, the port operator announced that it was working with the government to free the mountain of shipping containers, some of which had been moved to former airfields. The port had also hired staff and extended its opening hours to remove the congestion.

Felixstowe had filed complaints prior to the pandemic. According to IHS Markit, it is one of the least efficient container ports in the world. It is struggling to cope with growing international trade and larger ships with more containers. Moving a container onto or from a ship in Felixstowe takes twice as long as some of China’s busiest ports, IHS Markit data shows.

With Felixstowe and other deep-sea ports mostly handling trade from Asia, these delays are not the same as in the New Year when the UK breaks away from its largest trading partner.

From January 1st, the UK’s trade relations with the European Union will change, introducing customs controls and possibly tariffs. While a trade deal is still being negotiated, the border processes will change regardless. For the first time, hundreds of thousands of businesses will have to meet customs controls and other new trade requirements.

The government has warned companies to prepare, but trade groups say some companies are too busy with the aftermath of the pandemic. Mr Ward said importers and exporters are less prepared, even though warehouses and transport companies have done what they can.

The crux of the matter is likely to be on the south coast, in Dover or Folkestone, the busiest places for goods to be transported between Great Britain and the European Union, either with trucks, which are transported by ferries across the English Channel, or with trains through the Channel Tunnel.

Categories
Health

‘Small City, No Hospital’: Covid-19 Is Overwhelming Rural West Texas

ALPINE, Texas – It’s one of the fastest growing coronavirus hotspots in the nation, but there are no long lines of cars piled up for drive-through tests and no rush of appointments to be wiped down at CVS.

That’s because in the rugged, rural expanse of far west Texas, there isn’t a county health department that can get daily tests and no CVS business for more than 100 miles. A handful of clinics offer tests for those who can make an appointment.

Behind the teetering oil platforms of Midland and Odessa, where real road runners scurry down two-lane roads and desert bushes freckle the long, beige horizon, the Big Bend region of Texas is one of the most remote parts of the American mainland and one of the least equipped to break out to treat infectious diseases. There is only one 12,000 square kilometer hospital and no heart or lung specialists to treat serious cases of Covid-19.

But as a sign that the virus is on the rise almost everywhere, the counties that Big Bend belongs to were in the nation’s top 20 for most new cases per capita last week.

Known for its sprawling national park and the artist town of Marfa, Big Bend provides an extreme example of the danger that is unfolding across the country as the virus flares further and more furiously than ever, driving deaths to levels seen since spring and push many places into crisis at the same time. From California to Texas to Mississippi, hospitals and health officials in rural communities are increasingly concerned that they are alone.

“There is no neurologist, there is no long-term care specialist,” said Dr. JP Schwartz, Big Bend’s Presidio County health department and a doctor at a local clinic. “We don’t want to help them at all. There isn’t even a nursing home out here. “

Even with Texas hospitalizations and deaths near their summer peaks, local officials fear they have little power to intervene beyond the measures taken by Republican Governor Greg Abbott.

“My hands are tied,” said Eleazar R. Cano, the Brewster County judge, who said he was advised against issuing a stay at home order or other stricter measures that could violate the governor’s order. Mr. Cano, a Democrat, likened governing during the pandemic to driving his truck through the desert with an empty gas tank without a cell phone operator calling for help.

“It’s helpless, frustrating, almost panicking,” he said.

On the long miles between the sparsely populated cities of Big Bend, it’s hard to fathom how a virus that thrives on human contact can flare up in a place so vast. Falcons rule in the great blue sky. Cell phone service is spotty. Christmas decorations along the street are not in people’s homes, but on the gates of their ranch.

But somehow new cases have exploded in the past few weeks.

In Brewster County, a sprawling giant of 9,200 residents in an area of ​​6,000 square miles, more than half of the 700+ known cases were identified last month. In neighboring Presidio County of 6,700 people near the Mexico border, cases have quadrupled from less than 100 to more than 470 in the past two months. Both communities are older, with 65 and over making up about a quarter of the population.

“The numbers are rising at this point,” said Malynda Richardson, the presidio city ambulance director, who coughed sporadically as she recovered from the freezing chills and knockout exhaustion of Covid-19.

There are a number of reasons for the spike.

The area is so remote that local residents have to travel to El Paso or Odessa to schedule a doctor’s appointment and buy essentials at Walmart. With cases popping up across west Texas, the virus may have come back with them. Officials also cited border traffic from Mexico, cases among young people at Sul Ross State University, and an increase in tourists who were not deterred by the pandemic.

Big Bend National Park visitor numbers rose 20 percent in October, park officials said, and so many cars clogged the park over Thanksgiving weekend that it jammed. In the liberal artist outpost of Marfa, young people from Austin and Dallas roam the city, sipping on almond milk and photographing murals that ask existential questions such as, “Is austerity an illusion?” A recent art installation caused a stir during the pandemic with an obvious message against tourism: “Everyone here hates you.”

However, it turns out that tourism isn’t the biggest part of the problem.

The limited contact tracing in the region shows greater local penetration – in bars, in multi-generational homes, and by people who ignore positive test results and continue to work and socialize as usual.

In Alpine, the largest city with 5,900 residents, residents wear masks with their cowboy hats to shop at Porter’s grocery store, but remove them to eat inside at local restaurants. There is no general consensus on whether masks are necessary and effective. In a sign of the controversy that has played out on social media and off-social media, the county was left without a local health authority when the doctor in the position, a volunteer pediatrician, resigned this fall after being told by local residents who opposed, had been pushed back mask orders and other restrictions.

Brewster County, which also includes Alpine, has already ordered bars to shut down and reduce food in indoor restaurants from 75 percent to 50 percent, as the governor’s order for counties with a high percentage of Covid-19 hospital stays prescribes. However, enforcement is incomplete, and the governor has prohibited local officials from imposing stricter rules than his own.

Because of the scarcity of resources, local health clinics are a prime option for testing, but even then, the swabs must be driven to El Paso for three hours and flown out of Dallas for processing in Arlington. The National Guard also offers regular tests. In response to the growing crisis, new mobile test vehicles should arrive this week.

For those who get seriously ill, the hospital, the Big Bend Regional Medical Center in Alpine, only has 25 beds and a makeshift Covid ward where patients were confiscated at the end of the lonely, L-shaped hallway.

Dr. John Ray, a family doctor who works shifts at the hospital, said the hospital had received consecutive calls for incoming coronavirus patients on a final day. One of them had to be taken to a larger hospital in Odessa to receive special care.

Not long after that, said Dr. Ray, he saw the patient’s obituary in the newspaper.

“I don’t want to see Alpine like the pictures you see in New York, just people dying in hallways and waiting for a bed,” said Dr. Ray, 44, who grew up in the small town of Troup, East Texas, Wisconsin for his residency and then returned to Texas to settle in the Big Bend for Beauty and People area in 2013. He and his wife, also a doctor, usually treat a lot of sore throats, urinary tract infections, and pregnancy visits. Now he said: “It’s Covid, Covid, Covid.”

Higher-level hospitals are also full across West Texas. El Paso, which was recently so inundated with infection that it created mobile morgues, is still recovering from its own virus deluge. Lubbock recently had up to 50 percent of beds filled with Covid patients, and on a particularly bad day last week, the city reported that overall hospital capacity was depleted.

Dr. Ray fears there may be a day when critically ill patients who would normally be moved to another location run out of options. “To be very clear,” he said, “if you can’t go anywhere else, you will die here.”

A spokeswoman for Big Bend Regional Medical Center said the hospital has had room so far, adding ventilators, oxygen tanks and nurses to prepare for a surge. Of nine patients in the hospital on Wednesday, four had Covid-19.

Even so, many remain concerned. Simone Rubi, 46, graphic designer and musician who owns a café in Marfa, about 30 minutes by car from the Alpine hospital, hung a poster in front of her to-go window and summarized the precarious situation in four words: “Small town, no hospital . “

“There will be no place for us if we get sick – that’s the bottom line,” she said, sitting on a picnic bench outside her shop on a Saturday morning.

“We’d have to go to Dallas,” said her husband Rob Gungor, who said he had asthma and was resigned to making the nearly eight-hour drive to an Airbnb near a major hospital if he contracted the virus to get it to be around in case it turns bad. Like most people in Marfa, who accepted masks more easily than some other cities in Big Bend, he also wore a mask outdoors.

“Maybe Phoenix,” he added, “because it’s only a nine-hour drive.”

For those living in even more rural parts of West Texas, navigating the coronavirus spike has consequences that go well beyond the virus itself.

There is only one full-service ambulance covering 3,000 square miles in the border community of Terlingua. In some cases, paramedics had to drive coronavirus patients to Alpine hospital for three hours to clear the area for other serious emergencies.

“That has always been our draw – it’s an isolated, beautiful, pristine landscape,” said Sara Allen Colando, Terlingua District Commissioner. But as the cases rise, the wilderness is also its own peril.

“If you have to take someone to God with Covid, where, how long does it take to get this ambulance back up and running?” She said. “Who will be there to take the call?”

Mitch Smith contributed to coverage from Chicago.

Categories
Entertainment

‘A Canine Referred to as Cash’ Assessment: Lyrical Encounters With PJ Harvey

While she was making her album “The Hope Six Demolition Project” in 2016, musician PJ Harvey did something rare: she opened up her recording process to the public. She and her team built a studio in London in which fans of the musician or just the curious could see Harvey and her musical staff laying down the tracks.

In the chronicles of “A Dog Called Money” this was the culmination of a lengthy workflow. The songs began as writings when Harvey spent time in Kabul, Kosovo, and Washington DC with photojournalist Seamus Murphy, who also directed this picture

In search of inspiration, Harvey visited not only places of plague, but also places of joy, such as a musical instrument shop on the upper floor of a shop window in Afghanistan. She thought about her own privilege – she explored the destroyed records and pieces of furniture in a bombed-out house in Kosovo and remarked: “I step on your things in my expensive leather sandals.”

A scene with a DC gospel choir contributing to one of Harvey’s songs is a bit awkward. Harvey is respectful and kind. But even in the supposedly best of circumstances, white artists who guarantee some form of authenticity by inviting people of color to expand their work can seem a little patronizing.

The most compelling sections of this film take place in this temporary London studio. Harvey is detail-oriented, in a good mood, dedicated and encourages her fellow musicians. The melodies she crafted for the resulting record are complex and eclectic, yet still honor the raw directness of her early work.

A dog called money
Not rated. Running time: 1 hour 34 minutes. Take a look at the virtual cinema of the Filmforum.

Categories
Business

Lowe’s expects gross sales to rise about 22% in fiscal 2020

Customers support Lowes Hardware Store in Farmingdale, New York on May 20, 2020.

Bruce Bennett | Getty Images

Lowe’s said Wednesday that it expects sales to grow about 22% over the next year as its turnaround efforts gain momentum and the popularity of home improvement projects receives a boost during the coronavirus pandemic.

Revenue in the same store is expected to grow about 23% over the same period, helping the company earn between $ 7.53 and $ 7.63 per share. After adjustments, Lowe projects earnings of $ 8.62 to $ 8.72 per share.

Speaking at an investor meeting, Lowe CEO Marvin Ellison said the company will pursue a “total home” strategy as it expands its strategy A selection of products that homeowners and home professionals need, from kitchen appliances to home decor, and provide a better customer experience.

He highlighted the investments and improvements Lowe’s already made in brick and mortar and digital businesses. A loyalty program was launched among them to attract more business from home professionals such as electricians and building contractors. The website has been redesigned to simplify navigation and better handle data traffic. In addition, new digital fulfillment options have been added, such as: B. Roadside pickup and in-store lockers.

“Our commitment to retail fundamentals was critical to our financial success in 2020,” he said. “Our supply chain, in-store and digital systems would have collapsed under the weight of the unprecedented customer demand created by the pandemic without that focus.”

Still, he added, “The best days at Lowe are ahead of us,” as the company turns its attention to entering the home improvement market, valued at approximately $ 900 billion.

Dave Denton, Lowe’s chief financial officer, said his efforts over the coming months would increase the company’s revenue per square foot. He said it expects to reach $ 423 per square foot by the end of this year and will increase its target to $ 460 for the future.

“2020 was a pivotal year for the company,” he said. “We are taking market share earlier than expected and making the right investments for future growth.”

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Categories
Health

UK regulator warns these with historical past of serious allergic reactions

Assistant Nurse Katie McIntosh gives Vivien McKay, Clinical Nurse Manager at Western General Hospital, the first of two Pfizer / BioNTech COVID-19 stitches on the first day of the largest vaccination program in UK history in Edinburgh, Scotland, UK December 8 2020.

Andrew Milligan | Reuters

LONDON – People with a history of “significant” allergic reactions should not receive the coronavirus vaccine developed by Pfizer and BioNTech, the UK Medicines Agency said on Wednesday.

The UK drug and health products regulator has updated its guidance to UK health care providers on who should get the vaccine after two members of the UK National Health Service had allergic reactions to the shot. Both are recovering well, according to the NHS national medical director.

“People with a history of significant allergic reaction to a vaccine, drug, or food (such as a history of anaphylactoid reaction or someone recommended to wear an adrenaline auto-injector) should not receive the Pfizer BioNtech vaccine received, “the regulator said.

Stephen Powis, national medical director for the NHS, said such a precaution was “common with new vaccines”.

The UK was the first country to approve and administer the Pfizer BioNTech vaccine. A massive vaccination campaign began on Tuesday that began in hospitals, with health and nursing home workers and those over 80 being vaccinated first.

Dr. June Raine, head of MHRA, told a UK government selection committee on Wednesday that the regulator would maintain “real-time vigilance” of the vaccine after its use.

“Last night we looked at two case reports of allergic reactions,” she said.

“We know from extensive clinical studies that this was not a feature. However, if we need to step up our advice after having this experience in vulnerable populations, the priority groups, we will get that advice on the spot immediately.”

Categories
Politics

We’ve Reached ‘Secure Harbor’ – The New York Occasions

  • With a flick of the wrist the Supreme Court reduce a Republican attempt to reverse the loss of President Trump in Pennsylvania. In a one-sentence ruling yesterday, the court declined to hear a challenge to the use of postal ballot papers in Pennsylvania without public opposition from the judges.

  • It was a clear rejection of Trump’s attempts to contest the election by a court that includes three judges he appointed and which he had hoped for after the election.

  • The country yesterday hit what electoral officials call the “safe harbor,” which is widely viewed as the date by which all state-level electoral challenges, such as recounts and audits, must be completed. State courts will likely commence a new lawsuit against the election after this period. Whether he openly admits it or not, Trump’s attempt to overturn the election seems nearing the inevitable end.

  • The White House submerged again Stimulus negotiations with Congressional Democrats yesterday with a $ 916 billion proposal that Treasury Secretary Steven Mnuchin shared with House Speaker Nancy Pelosi and Senate Majority Leader Mitch McConnell. The deal would include one-time cash payments to Americans and aid to state, local, and tribal governments.

  • The proposal also includes a provision that gives employers who have employed workers during the pandemic full immunity. This is an important Republican request, but Democratic leaders have said they are unwilling to cross that line.

  • McConnell announced early yesterday that if the Democrats gave up seeking billions of dollars for state and local governments, he would be dropping his demand for full liability coverage. But democratic leaders were quick to reject the idea.

  • Now that it’s in a lame duck sessionCongress seems unusually busy. The House yesterday passed a military spending bill that includes the removal of Confederate names from American military bases, which President Trump has vetoed.

  • This creates the potential for the first veto suspension of Trump’s presidency. The law was passed with a veto-proof bipartisan majority of 335 to 78 and is now going to the Senate, where overwhelming support is expected.

  • Congress has passed a successful law on military spending for the past 60 years. But the president remains against it. “I hope the Republicans of the House will vote against the very weak National Defense Authorization Act (NDAA) that I will VETO,” Trump wrote on Twitter.

  • Joe Biden will elect Marcia Fudge to represent herThe Ohio Democrat is slated to serve as secretary for housing and urban development, bringing Tom Vilsack back to his old job as secretary of agriculture, according to people familiar with the president’s transition process.

  • Meanwhile, retired General Lloyd Austin, whom Biden wants to appoint as Secretary of Defense, encounters bipartisan opposition over concerns about choosing another former commander to run the Pentagon. The recent trend has defied the longstanding tradition of civilian control over the military.

  • Austin, who would become the country’s first black Secretary of Defense, would face a waiver from Congress because he left the service less than seven years ago. Congress granted Jim Mattis a waiver four years ago to serve as Trump’s first secretary of defense.

  • Adding to concerns about Austin, however, are its ties to Raytheon, a defense company that makes billions of dollars selling weapons and military equipment to the US and other countries, creates what critics have termed a conflict of interest.

  • Biden officially introduced the core team of health officials This will guide his response to the Wilmington, Delaware pandemic to announce an ambitious plan to “get at least 100 million Covid vaccine shots into the arms of the American people” in his first 100 days as president.

  • The promise poses at least some risk to Biden, as fulfilling the promise does not require any problems in making or distributing the vaccine and the willingness of Americans to be vaccinated.

  • As he spoke, Biden was flanked by members of his team, some of whom joined by video. These included Dr. Anthony Fauci, who will serve as Biden’s premier medical advisor while continuing to serve as the country’s foremost infectious disease expert, and Dr. Rochelle Walensky, who will be director of the Centers for Disease Control and Prevention.

  • Both made speeches, as did Xavier Becerra, Biden’s candidate for the Ministry of Health and Human Services, and Dr. Marcella Nunez-Smith from Yale University Medical School, who will lead a new Covid-19 Equity Task Force. The virus’s impact has been disproportionately focused on color communities, and Nunez-Smith spoke of “centering equity in our response to this pandemic rather than a secondary concern, not a checkbox, but a shared value.”

  • Britain became the first yesterday Land to begin administering the Pfizer BioNTech coronavirus vaccine to civilians, the start of a mass vaccination campaign unlike anything seen in recent times. (And trust the UK was very British indeed: the second person to receive the vaccine was none other than William Shakespeare, 81), a Warwickshire man who had been hospitalized for several weeks after having had a stroke was.)

  • The FDA is expected to approve the vaccine this week, and Trump celebrated the milestone at a “vaccine summit” near the White House. He spoke to a fully occupied, mostly masked crowd of industry representatives and members of his administration and declared the development of the vaccine a “monumental national achievement”.

  • When asked why he hadn’t invited Biden’s transition team to the summit, Trump reiterated his baseless claims that the election had been stolen and said he was still expecting another term.

  • Categories
    World News

    Iran Claims Arrests in Killing of High Nuclear Scientist

    Iranian authorities have arrested a number of people allegedly involved in the murder of the country’s top nuclear scientist last month near Tehran, a parliamentary adviser told an Iranian state broadcaster on Wednesday.

    The adviser, Hossein Amir Abdollahian, did not say how many people had been arrested in connection with the death of scientist Mohsen Fakhrizadeh and did not reveal their identity, according to Al Alam News Agency.

    “Those involved in this attack, some of whom have been identified and even arrested by security services, cannot escape the judiciary,” said Abdollahian, a former deputy foreign minister who is now an adviser to the President of Parliament. after a transcript of the interview. He added that the authorities would “react firmly to them and make them regret their actions”.

    According to American and Israeli officials, Fakhrizadeh was seen as the driving force behind Iran’s secret nuclear weapons program, and the brazen assassination left Tehran in shock and embarrassment. The scientist was ambushed on a country road, although conflicting reports about the conduct of the assassination exposed tensions between rival factions in the Iranian government as each tried to shift the blame.

    Shortly after the murder, at least three officials said Israel was behind the attack, and since then Israeli officials have all but publicly acknowledged the responsibility.

    It remained unclear how much the United States might have known about the operation in advance, but the two allies have long exchanged information about Iran, particularly its nuclear program.

    Mr Abdollahian said that the Iranian authorities believed the Israelis had help coordinating the assassination of Mr Fakhrizadeh, adding “there is no doubt” that there was also American involvement.

    Categories
    Business

    Consultants Debate How To Put together For the Subsequent Pandemic

    The Food and Drug Administration will hold a hearing this week to determine whether to grant emergency authorization to a coronavirus vaccine developed by Pfizer and BioNTech. The vaccine, which the companies claim is 95 percent effective, is one of two that could be ready for injections in the United States before the end of this year. The other, by Moderna, will be considered by the regulator for emergency approval next week. In early trials, the vaccine appeared to prevent the development of Covid-19 in around 94 percent of recipients.

    The news is a welcome development in the otherwise grim saga of the fight against the coronavirus. The United States averages around 200,000 new cases each day, and more than 2,000 deaths.

    An effective and widely available vaccine has long been promoted as the lifeline that will curb infections, save lives and pull a battered economy back from the brink. Yet the impending arrival of one or more vaccines raises questions about equity, education and how battered American institutions should prepare for the next pandemic, while repairing the damage wrought by this one.

    As part of the DealBook D.C. Policy Project, The New York Times gathered a virtual panel of experts in early December to discuss the policy environment in a post-Covid world — or, at least, a post-Covid vaccine world.

    The participants:

    • Ruth Faden, professor of bioethics at Johns Hopkins University

    • James E.K. Hildreth, professor of internal medicine, president and chief executive of Meharry Medical College

    • Marc Lipsitch, professor of epidemiology and director of the Center for Communicable Disease Dynamics at Harvard T.H. Chan School of Public Health

    • Thomas M. Moriarty, chief policy and external affairs officer and general counsel at CVS Health

    • Gregory A. Poland, professor of medicine and infectious diseases and director of the Vaccine Research Group at the Mayo Clinic

    • Monica Schoch-Spana, medical anthropologist and senior scholar with the Johns Hopkins Center for Health Security

    • Moderated by Carl Zimmer, The Times’s “Matter” columnist

    An effective vaccine will be a huge breakthrough for society and the economy. But will it as effective in practice as in studies?

    Gregory Poland of the Mayo Clinic, who is also editor in chief of the journal Vaccine, explained the extent to which early results of the various vaccine trials have defied even optimistic expectations. He described it as “as nothing short of dizzying,” and added:

    “We were all prepared to see something like 50 to 70 percent efficacy, something like that. And to be in excess of 90 percent, 95 percent, puts it on par with the best vaccines that have ever been developed — and with apparent acceptable short-term safety. I think this is really going to have a profound effect on the field of vaccinology. I hate to overuse the word ‘paradigm-breaking,’ but it is, in many ways, to see something come to fruition within eight months like this.”

    But Mr. Poland also warned of “surprises” when measuring the impact of the first generation vaccines:

    “The efficacy measures we have were at times of relatively low transmission of disease compared to now. It was with masks on with people distanced, none of which will be true in time. So we may see some differences.”

    Who should be first in line for the vaccinations? What’s fair when allocating a limited number of shots?

    Even if vaccine injections are approved for use before the end of the year, the vast majority of people in the United States won’t notice any appreciable difference in their lives for at least three months, said Marc Lipsitch. Cases will continue to rise as winter temperatures force more people indoors, and there won’t yet be enough doses to cover the population.

    That raises some thorny questions.

    Earlier this month, the Advisory Committee on Immunization Practices at the Centers for Disease Control and Prevention voted to vaccinate health care workers and nursing home residents first. It proposed placing essential workers like bus drivers and grocery workers in the next tier of recipients.

    Mr. Lipsitch is among those who supports the alternative recommendation of the National Academies of Sciences, Engineering and Medicine to dole out the vaccine based on people’s health conditions rather than their working ones:

    “The only certain way, given what we know about the vaccine now, to get society back to being able to function is to have this be a less-severe disease. And the way you do that is to make the people in whom it’s severe no longer vulnerable.”

    But Mr. Lipsitch also acknowledged that the vaccine might never fully rid the world of Covid-19. “I can’t conceive of its disappearing,” he said. “Viral infections this widespread don’t disappear on their own that I’m aware of, unless they’re out-competed by some new strain.”

    He suggested, however, that Covid-19 might become less severe in the long term. “If everybody essentially in the world who’s not a newborn has either had the virus or had the vaccine,” he said, “there would be some immunity to severity, and some immunity to transmission, and so if I had to make a guess I would say it would become a seasonal disease like the flu.”

    Your neighborhood pharmacy will soon become a major player in vaccine distribution.

    Getting a Covid-19 vaccine to millions of people in every corner of the country is, of course, a huge logistical undertaking. Rather than relying on public health networks, the Trump administration has placed the nation’s two largest for-profit pharmacy chains, CVS and Walgreens, at the center of the nation’s vaccination effort.

    That also puts those chains at the forefront of an effort to educate the public about a new vaccine, and to convince the many skeptics that the rapidly developed shot is safe. Thomas Moriarty of CVS Health shared a little of what that task looks like, noting that about three-quarters of all Americans live within three miles of a CVS, “and we have the ability to extend beyond that through vaccination clinics.”

    The Road to a Coronavirus Vaccine

    Words to Know About Vaccines

    Confused by the all technical terms used to describe how vaccines work and are investigated? Let us help:

      • Adverse event: A health problem that crops up in volunteers in a clinical trial of a vaccine or a drug. An adverse event isn’t always caused by the treatment tested in the trial.
      • Antibody: A protein produced by the immune system that can attach to a pathogen such as the coronavirus and stop it from infecting cells.
      • Approval, licensure and emergency use authorization: Drugs, vaccines and medical devices cannot be sold in the United States without gaining approval from the Food and Drug Administration, also known as licensure. After a company submits the results of  clinical trials to the F.D.A. for consideration, the agency decides whether the product is safe and effective, a process that generally takes many months. If the country is facing an emergency — like a pandemic — a company may apply instead for an emergency use authorization, which can be granted considerably faster.
      • Background rate: How often a health problem, known as an adverse event, arises in the general population. To determine if a vaccine or a drug is safe, researchers compare the rate of adverse events in a trial to the background rate.
      • Efficacy: The benefit that a vaccine provides compared to a placebo, as measured in a clinical trial. To test a coronavirus vaccine, for instance, researchers compare how many people in the vaccinated and placebo groups get Covid-19. Effectiveness, by contrast, is the benefit that a vaccine or a drug provides out in the real world. A vaccine’s effectiveness may turn out to be lower or higher than its efficacy.
      • Phase 1, 2, and 3 trials: Clinical trials typically take place in three stages. Phase 1 trials usually involve a few dozen people and are designed to observe whether a vaccine or drug is safe. Phase 2 trials, involving hundreds of people, allow researchers to try out different doses and gather more measurements about the vaccine’s effects on the immune system. Phase 3 trials, involving thousands or tens of thousands of volunteers, determine the safety and efficacy of the vaccine or drug by waiting to see how many people are protected from the disease it’s designed to fight.
      • Placebo: A substance that has no therapeutic effect, often used in a clinical trial. To see if a vaccine can prevent Covid-19, for example, researchers may inject the vaccine into half of their volunteers, while the other half get a placebo of salt water. They can then compare how many people in each group get infected.
      • Post-market surveillance: The monitoring that takes place after a vaccine or drug has been approved and is regularly prescribed by doctors. This surveillance typically confirms that the treatment is safe. On rare occasions, it detects side effects in certain groups of people that were missed during clinical trials.
      • Preclinical research: Studies that take place before the start of a clinical trial, typically involving experiments where a treatment is tested on cells or in animals.
      • Viral vector vaccines: A type of vaccine that uses a harmless virus to chauffeur immune-system-stimulating ingredients into the human body. Viral vectors are used in several experimental Covid-19 vaccines, including those developed by AstraZeneca and Johnson & Johnson. Both of these companies are using a common cold virus called an adenovirus as their vector. The adenovirus carries coronavirus genes.
      • Trial protocol: A series of procedures to be carried out during a clinical trial.

    One of Mr. Moriarity’s biggest concerns is whether people will be willing to take the vaccine. His team surveys up to 7,000 people two to three times a week about what he called the “hesitancy rate,” he explained:

    “What we have seen in the data since getting past the election, and with the efficacy results of these vaccines becoming public, is that the hesitancy rate is starting to drop. There’s still going to be a core element of hesitancy — no question about it — but getting past the politics and seeing the results of the science is helping alleviate some of that hesitancy.”

    The country needs to re-establish trust in institutions, because pandemics are here to stay.

    Much of the conversation about the coronavirus pandemic has focused, understandably, on “getting back to normal.” Yet the inescapable truth is that, in many ways, there is no going back to the world as it was before the coronavirus. In a global economy in which pathogens can spread more quickly than ever before, the question is not if there will be another global pandemic, but when.

    Monica Schoch-Spana, a medical anthropologist who studies the ways communities respond to disaster, talked about what needed to be done to repair institutions that struggled during this crisis to clearly and effectively communicate with the public:

    “This is about trust, and trust building, and processes of reconciliation. And that takes time. And during that time, we can improve our messaging and involve trusted messengers. But what we’re talking about is re-establishing trust in institutions. We have to build processes for that, and strengthen the ones that are already there.”

    She said that efforts to persuade the public to accept the vaccine will have to include different messages targeted at different communities:

    “There will be certain messages that resonate really well in Baltimore City among local Black communities that may not resonate well with rural frontier Hispanics in southeastern Idaho. So we have to have those very hyperlocal perspectives.”

    When it comes to public health education, the messenger is at least as important as the message.

    Black, Latino and Asian communities have disproportionately borne the brunt of coronavirus cases in the United States. And yet, thanks to a legacy of racism in the American medical system, many in those communities are particularly wary of receiving the vaccine. Black adults, in particular, have expressed higher rates of vaccine hesitancy than others in the United States, a wariness fueled by the historical example of forced injections, forced sterilizations, unethical experimentation and other acts administered in the name of public health.

    Opposition to the vaccine within these communities is of particular concern to James Hildreth, an immunologist who spent decades on H.I.V. and AIDS research as a professor at Johns Hopkins before taking over in 2015 as president of Meharry Medical College, a historically Black medical school in Nashville. He discussed his experience with what works in public health education — and what does not. “We discovered that the messages were fine, but if the messenger is not trusted you’re wasting your time,” he said:

    “So we identified trusted messengers in those communities. We empowered them with the information they needed. They needed to believe it first — and accept it first — and they were the ones that delivered the messages that turned out to be quite effective. So that’s the model we’ve adopted to try to engage and reach minority communities with the vaccine.”

    We have to take care of the virus. Then we have to take care of everything else.

    The vaccine is not the end of the pandemic recovery period, but the beginning. Once the virus is under control, the nation faces disarray: millions of people unemployed, communities shattered by the loss of businesses, a generation with a disrupted education and deepened systemic inequalities.

    “The pandemic did more than just make us physically sick,” said Ruth Faden, a bioethicist. But she explained how this pain could become a catalyst for a better society:

    “I think it’s possible to envision a way in which for some of these horrible gaps in access, and the consequences that are lifelong for people’s prospects for a decent life, there will be an effort to fix them, perhaps with some urgency. I have to hope that something like that will happen as a consequence of what we’ve all gone through — and if not, it will be profoundly depressing.”

    Categories
    Health

    Kids’s hospitals are pitching in to assist with the flood of grownup Covid-19 sufferers.

    With Covid-19 patients on the rise threatening to overwhelm hospitals, U.S. public health officials are reaching for a safety valve the Northeast used in the spring: borrowing beds in children’s hospitals to care for adults.

    U.S. hospital stays hit a record high of 104,600, according to the Covid Tracking Project, and the nation set a record for the most deaths in a seven-day period last week.

    “When the fall came in and the second spike hit, we’re seeing a lot more of it now,” said Amy Knight, president of the Children’s Hospital Association, a national group that represents more than 200 US facilities.

    According to Dr. Peter Jay Hotez, Professor of Pediatrics and Molecular Virology and Microbiology, it is rare in American children’s hospitals to admit adult patients or to relax their admission criteria. The fact that this is happening now speaks to the severity of the crisis at Baylor College of Medicine and co-director of Texas Children’s Hospital Center for Vaccine Development.

    “I don’t even know if this happened during the first half of 2009, so I can’t think of too many modern precedents,” he said.

    Since coronavirus infections appear to largely spare younger children compared to teenagers and adults, children’s hospitals and the children’s wards of general hospitals tended not to be flooded at the beginning of the pandemic.

    “It was more like a trickle of children being hospitalized,” Ms. Knight said.

    Since then, however, the number of children who become infected and need hospital care has risen sharply, and children’s hospitals may have less space and resources available if the need for pediatric beds due to influenza increases anyway.

    “We are much less able to treat pediatric critical diseases across the country,” said Dr. Brian Cummings, who works in the intensive care unit at MassGeneral Hospital for Children in Boston. “Obviously we are overwhelming the capacity of the adult intensive care unit, and using an even scarcer resource affects all of us who care about children.”

    Even so, children’s hospitals are helping with the rise in the coronavirus in a number of ways. The Association of Children’s Hospitals published guidelines in April for several possible approaches, including admitting pediatric patients from general hospitals to free up space in these facilities and increasing their maximum admission age.

    St. Louis Children’s Hospital, part of BJC HealthCare, opened its doors to adult patients in November, and another St. Louis children’s hospital, Cardinal Glennon Children’s Hospital, has accepted transfers for adults without Covid-19. Oishei Children’s Hospital in Buffalo said it will temporarily raise the admission limit to admit patients up to 25 years of age.

    During the first major surge in the northeast from April to June, the MassGeneral Hospital for Children admitted adult patients to its 14-bed intensive care unit. “When we saw how hospitals were overwhelmed, everyone wanted to do their part,” said Dr. Cummings.

    The unit returned to normal in the summer, but with Massachusetts cases picking up again, he said, “We’re definitely worried we’ll have patients again in the next week or two.”

    Categories
    Politics

    Biden defends nomination of not too long ago retired Gen. Austin for Protection secretary

    WASHINGTON – President-elect Joe Biden on Tuesday defended his decision to appoint retired four-star Army General Lloyd Austin as his Secretary of Defense, a personnel election that could become one of the future president’s most controversial.

    Under the National Security Act of 1947, Congress prohibited anyone from serving as secretary of defense for seven years after active service. But Austin only left the army four years ago, and he would require a special waiver from Congress to circumvent the seven-year rule.

    Biden wrote in The Atlantic, tacitly admitting that Austin’s nomination was against civilian requirements, but argued that the strength of Austin’s qualifications outweighed the potential damage caused by blurring the civil-military divide.

    “I respect and believe in the importance of civilian control of our military and the importance of a strong civil-military working relationship at DoD – as does Austin,” Biden wrote.

    “Austin also knows that the Secretary of Defense has different responsibilities from an officer-general and that the civil-military dynamic has been under great pressure over the past four years,” Biden wrote.

    If this were confirmed by the Senate, the 1975 graduate of West Point would be the first black Pentagon leader to break through one of the more permanent glass ceilings of the US government.

    U.S. Central Command Commander General Lloyd Austin III holds a press conference on Operation Inherent Resolve, the international military effort against the Islamic State Group (IS), on October 17, 2014 at the Pentagon in Washingon, DC.

    Paul J. Richards | AFP | Getty Images

    Austin also has a personal relationship with Biden after gaining the President-elect’s trust and confidence in leading the global coalition against ISIS, which began in 2014, while Biden was Vice President and Austin led US Central Command.

    Biden also emphasized in his Atlantic essay that despite Austin’s recent active service, he understands “that our military is only an instrument of our national security”.

    “To keep America strong and secure, we must use all of our tools,” wrote Biden. “He and I share an obligation to empower our diplomats and development experts to guide our foreign policy, using violence only as a last resort.”

    Still, news of Austin’s likely nomination this week on Capitol Hill was met with skepticism, and several key Senators said they were not sure they would vote to give Austin the waiver necessary to take the position of Secretary of Defense .

    “That’s the exception, not the rule,” Majority Whip John Thune, RS.D., told reporters Tuesday. “I’m not including or excluding it. But I think it’s something we need to consider when the time comes.”

    Montana Democratic Senator Jon Tester also said he was unwilling to give Austin a waiver, even though the retired commanding officer would be “a great secretary”.

    “I think this guy is going to be a great secretary,” Tester told reporters. “I just think we should look at the rules.”

    Congress put aside its concerns about a military officer’s leadership of the Pentagon in 2016 when President Donald Trump addressed retired four-star general of the U.S. Marine Corps, Jim Mattis, who at the time had only been out of uniform for three years .