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Health

Does Double-Masking Assist Sluggish the Unfold of Covid?

Football coaches do it. The elected presidents do it. Even academically savvy senators do. As coronavirus cases continue to rise around the world, some of the country’s most famous people have begun doubling down on masks – a move that researchers say is increasingly being backed by data.

Double masking is not necessary for everyone. But for people with thin or thin face coverings, “When you combine layers, you get pretty high levels of efficiency” by preventing viruses from leaking out of the airways and into the airways, said Linsey Marr, virus transmission expert at Virginia Tech and author of a recent commentary describes the science behind mask wearing.

Of course there is a compromise: at some point we run the risk of making it too difficult to breathe, she said. But there is plenty of room to breathe before mask wearing approaches this extreme.

A year after the Covid-19 pandemic, the world looks very different. More than 90 million confirmed coronavirus infections have been documented worldwide, leaving millions dead and countless others with lingering symptoms in ongoing economic hardship and closed schools and businesses. New variants of the virus have emerged that bring about genetic changes that appear to improve their ability to spread from person to person.

And while several vaccines have now cleared regulatory hurdles, injections adoption has been stuttering and slow – and there’s still no definitive evidence that gunshots will have a significant impact on how quickly and by whom the virus spreads.

Through all of these changes, researchers have kept the line with masks. “Americans don’t have to wear masks forever,” said Dr. Monica Gandhi, an infectious disease doctor at the University of California at San Francisco and author of the new comment. But for now they have to stay and offer protection to both those wearing the mask and the people around them.

The case for masking spans several areas of science, including epidemiology and physics. A host of observational studies have shown that the widespread use of masks can curb infection and death on an impressive scale, in settings as small as hair salons and at the country level. A study that tracked government policies that make face coverings mandatory in public found that known Covid cases with mask-wearing rules increased and decreased almost in lockstep. Another who followed coronavirus infections among health care workers in Boston saw a drastic decrease in the number of positive test results after masks became a universal part of the workforce. A study in Beijing found that face masks were 79 percent effective at blocking transmission from infected people to their close contacts.

Recent work by researchers like Dr. Marr now lay down the basis of these links on a microscopic scale. The science, she said, is pretty intuitive: respiratory viruses like the coronavirus, which move between people in spit and spray marks, need clear piping to get into the airways, which are overcrowded with the types of cells that the viruses infect. Masks that cover the nose and mouth prevent this invasion.

It’s not about making a mask airtight, said Dr. Marr. Instead, the fibers that make up masks create a random obstacle course that air – and any contagious cargo – must navigate.

“The air must follow this tortuous path,” said Dr. Marr. “The great things it bears will not be able to follow these turns.”

Experiments testing the ability of masks to block incoming and outgoing spray showed that even relatively simple materials, such as fabric covers and surgical masks, can be at least 50 percent effective in either direction.

Several studies have reinforced the notion that masks seem to protect people around the mask wearer better than mask wearers themselves. “That’s because you stop it at the source,” said Dr. Marr. Based on the latest research, the Centers for Disease Control and Prevention has found that there are great benefits for those who wear masks too.

The best masks remain N95, which are designed with ultra-high filtration efficiency. However, they are still in short supply for health workers who need them to safely treat patients.

Layering two less specialized masks can provide comparable protection. Dr. Marr recommended wearing face masks over surgical masks, which are typically made from more filter-friendly materials but fit more loosely. An alternative is to wear a cloth mask with a pocket that can be filled with filter material, as is the case with vacuum bags.

However, wearing more than two masks or applying masks that can already filter very well quickly leads to falling yields and makes normal breathing considerably more difficult.

Other improvements can improve the fit of a mask, e.g. B. Ties that secure the fabric at the back of the head instead of relying on ear loops to allow masks to hang and gape. Nose bridges, which can help the top of a mask fit tighter, also provide a protection boost.

Achieving great fit and filtration “is really easy,” said Dr. Gandhi. “It doesn’t have to contain anything special.”

No mask is perfect, and wearing a mask does not prevent other public health measures such as physical distancing and good hygiene. “We have to be honest that the best answer is one that requires multiple interventions,” said Jennifer Nuzzo, a public health expert at Johns Hopkins University.

Wearing masks is uncommon in some parts of the country, partly due to the politicization of the practice. However, experts found that the model behavior of heads of state and government could help turn the tide. In December, President-elect Joseph R. Biden Jr. pleaded with Americans to wear masks during his first 100 days in office and said he would make it compulsory in federal buildings as well as on planes, trains, and buses crossing state lines .

A comprehensive review of the evidence for masking published this month in PNAS magazine concluded that masks are a key tool in reducing community transmission and are “most effective at reducing the spread of the virus with high compliance.”

Some of the messages may also require more empathy, open communication, and voice recognition that “people don’t wear masks,” said Dr. Nuzzo. Without more patience and compassion, simply doubling the limits to “fix” poor compliance will backfire: “No policy will work if no one adheres to it.”

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Business

Brooklyn Nets star Kyrie Irving fined for violating NBA Covid-19 guidelines

Kyrie Irving # 11 of the Brooklyn Nets looks on during the game against the Washington Wizards on February 1, 2020 at Capital One Arena in Washington, DC. (Photo by Ned Dishman / NBAE via Getty Images)

Ned Dishman / NBAE via Getty Images

Brooklyn Nets stars Kyrie Irving have been fined $ 50,000 for violating Covid-19 protocols, the National Basketball Association said on Friday.

The NBA President Byron Spruell made the decision after Irving was seen wearing no mask at a “private indoor party” last weekend. His presence violated NBA rules, which prohibit players from “attending indoor social gatherings of 15 or more people or entering bars, lounges, clubs, or similar facilities.”

Irving, who will be paid $ 33 million by the Nets this season, will lose his salary for games he missed during his quarantine period. Despite having to suspend the networks for the last five games, Irving will only be docked for two games and will have to forego over $ 400,000 per game.

The NBA said Irving will be allowed to return on Saturday if he clears league logs.

Covid-19 outbreaks have hit the NBA hard this week, forcing the league to postpone numerous games since Monday, including Saturday’s Indiana Pacers competition against the Chicago Bulls. The league also released its latest pandemic test report, which found 16 new players tested positive.

To combat the outbreaks, the NBA tightened Covid-19 protocols to mandate more masks in team areas and issued a two-week stay-at-home policy. Players and team members must remain in their homes outside of team activities at practice areas or in arenas in their home markets.

In addition to Irving’s possible return, the Nets will also welcome James Harden to the club. The team traded with four teams for Harden on Wednesday.

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Business

Marsha Zazula, ‘Metallic Matriarch’ of Metallica and Others, Dies at 68

“Marsha and I went to bars and changed all the leaflets every two to three days,” wrote Mr. Zazula in his book, “and we posted telephone poles as if we were going to vote.”

In 1982 someone brought a demo tape from a West Coast band into the store. Realizing they were hearing something special, the zazulas urged the unknown band Metallica to come east to play some shows. The group crashed at the Zazula’s home for a while, “and things went a little crazy when women followed them home and ran around the house,” Ms. Zazula told Courier Post in Camden, New Jersey, in 2009. The Zazulas started Megaforce to release the band’s “Kill ‘Em All”.

Other bands and albums followed, with the zazulas often giving the musicians a place to stay and feeding them while barely feeding themselves.

“Marsha and I didn’t make any money,” Zazula-san said in Louder Than Hell. “We had just got into our first house and all of this happened when our children were born.”

As Ms. Zazula said in her interview with “Moguls and Madmen”: “Bologna was our filet mignon.”

Mr. Hetfield alluded to this time and Ms. Zazula’s role in his Instagram post.

“She was our mother when I didn’t have one,” he said. “She made great sacrifices to make Metallica grow.”

And the band or their popularity grew so much that after the release of the second Megaforce album “Ride the Lightning” in 1984 Metallica switched to a bigger label, Elektra. Other bands, including Anthrax, followed a similar path, breaking on the Megaforce label (Anthrax with the 1984 album “Fistful of Metal”) and then switching to a bigger one.

Categories
Health

Peter Thiel-backed psychedelics start-up ATAI targets schizophrenia

LONDON – ATAI Life Science, a Peter Thiel-backed start-up, has acquired a majority stake in Recognify, a company that develops drugs to treat schizophrenia.

ATAI is headquartered in Berlin and aims to manufacture psychedelics that can be used to treat mental disorders. Recognify, meanwhile, is specifically aiming to create a drug that can be used to treat the cognitive impairment associated with schizophrenia, or CIAS.

The latter company was co-founded by the German-American biochemist Thomas Sudhof, who received a Nobel Prize in Physiology or Medicine in 2013.

The terms of the deal were not disclosed, but ATAI said it was in the “tens of millions”.

ATAI, calling itself a drug development platform, was formed to acquire, incubate, and develop psychedelics and other drugs that can be used to treat depression, anxiety, addiction, and other mental illnesses. In return for a controlling stake in the drugs they develop, ATAI helps scientists raise money, work with regulators, and conduct clinical trials.

Treatment of schizophrenia

Recognify’s lead drug, RL-007, has been tested in nine clinical studies on 508 people, including rats, according to ATAI. Clinical trial results were not published.

Srinivas Rao, co-founder and chief scientist of ATAI, told CNBC through Zoom that Recognify has developed a “very interesting” compound that has been shown to have benefits.

“Things like verbal memory and things like that were actually greatly enhanced with this connection,” said Rao. “And that’s something that is deficient in patients with schizophrenia. So that’s really the requirement here. We want to extend the results that exist now to the schizophrenic population.”

Schizophrenia affects around 20 million people, according to the World Health Organization, which results in people hearing voices and seeing things that are not real through hallucinations, and can also cause disorganized and confused thinking.

IPO plans

The news of the Recognify deal comes after ATAI raised $ 125 million from investors like Thiel in November, ahead of a listing this year. The total investment in the company is now over $ 210 million.

“The great virtue of ATAI is taking mental illness as seriously as we should have,” said Thiel, co-founder of Palantir and PayPal, in a statement shared with CNBC at the time. “The company’s most valuable asset is its urgency.”

The two-year company, which has offices in Berlin, New York and San Diego, currently works with around 10 drug development companies.

According to an industry source who wanted to remain anonymous due to the nature of the discussions, there are plans to launch ATAI with a value between $ 1 billion and $ 2 billion in the next few months.

Categories
Business

NRF mentioned vacation gross sales rose 8.3%, topping estimates

People shop for vacation items at the country store on Main Street in Stockbridge, Massachusetts on December 13, 2020.

Joseph Prezioso | AFP | Getty Images

According to the National Retail Federation on Friday, holiday retail sales rose 8.3% from 2019 as consumers used the gift season as a way to cheer themselves up during the Covid pandemic.

“With the spread of the virus on the rise, government restrictions on retailers, and heightened political and economic uncertainty, consumers chose gifts that lifted the spirits of their families and friends and conveyed a sense of normalcy in the challenging year,” said Matthew Shay, president and CEO of the National Retail Federation, in a statement.

That is more than expected by the large retail group and more than double the average annual increase. NRF forecast in November that Christmas sales in 2020 will increase between 3.6% and 5.2% year over year, ranging from $ 755.3 billion to $ 766.7 billion. Americans were said to be spending more as they had less travel and dining expenses and were hoping for the Covid vaccine to be distributed.

Christmas sales have increased by an average of 3.5% over the past five years, and they have increased 4% in 2019, the NRF said. The sales exclude car dealerships, gas stations and restaurants.

The pandemic has messed up typical holiday shopping patterns. Many retailers started selling back in October and closed their shops on Thanksgiving. You have put more offers online and expanded contactless options, e.g. B. Roadside collection to reduce the number of shoppers in stores.

Even so, there were some factors that the retailer could not get hold of, such as economic insecurity and unemployment during the recession and fewer gatherings with family and friends.

NRF chief economist Jack Kleinhenz said the surge in Christmas sales was “truly phenomenal given the extremes this economy has been through”. He said the month-to-month numbers reflect push and pull of factors from temporary store closures and vacations to stimulus payments.

Ultimately, he said, consumer mindset and savings accounts inspired them to spend. He said the sales indicate that more people want a vacation that’s better than normal during a difficult year and that money has been put aside after they canceled their vacation and had fewer options to spend their money safely.

He said the desire to celebrate the holidays is great, even for low-income families and people who are unemployed.

“Vacation comes once a year and even the most economically challenged people still have an emphasis on vacation,” he said. “They will try to do the best they can.”

The Christmas sales also reflected pandemic trends such as: B. Cooking and sports at home and DIY projects. Online and other off-store sales saw the largest increase of nearly 24% year over year, according to the NRF.

Sales in building materials and gardening supplies stores rose nearly 20%. This was followed by sales of sports stores, which grew about 15%, and grocery and beverage stores, which grew nearly 10%. Sales in the health and personal care and furniture and home decor stores increased 5% and 2%, respectively.

Sales in general merchandise stores were virtually unchanged. However, sales in the electronics and housewares stores were down 14%. Sales in clothing and apparel accessory stores were down about 15%. Some laptop or pajama purchases were likely classified as online or non-in-store sales, as customers made purchases from their couches or used options like roadside pickup. Some electronics purchases may have been made earlier in the year when people were working at home and going to school.

Retailers have started reporting some of their individual sales results. Lululemon, which had strong sales in the leisure industry while working from home, forecast a fourth quarter profit at the high end of its expectations due to the strong holiday season. Comparable sales online and in-store rose 17% in November and December, according to Target, as vacation shoppers flocked to convenient, contactless options like roadside pickup. However, Nordstrom and Urban Outfitters reported disappointing holidays as many shoppers stayed away from malls.

Categories
Politics

A person with a gun arrested by Capitol Police at a safety checkpoint calls it an ‘sincere mistake.’

The US Capitol Police arrested a man at a security checkpoint in Washington on Friday after he flashed a personal identification card that an officer had labeled “unauthorized” and found an unregistered pistol and ammunition during a search of his truck.

A federal police officer said the man, Wesley A. Beeler, 31, was a contractor and that his ID was issued by the park police but not recognized by the police officer. The officer spoke on condition of anonymity as he was not authorized to discuss the arrest. Mr. Beeler has no known extremist relationships, the official said.

“It was an honest mistake,” Beeler told the Washington Post after he was charged with illegal possession of a firearm and released on Saturday afternoon. He said he did a security job in Washington, was late for work and forgot his gun was in his truck.

“I drove to a checkpoint after getting lost in DC because I’m a compatriot,” he told the Post. “I showed you the initiation badge that was given to me.”

The arrest comes after police officers tried to fortify Washington ahead of the inauguration day on Wednesday, fearing extremists encouraged by President Trump’s supporters’ attack on the Capitol on January 6, may attempt violence cause. A militarized “green zone” is being established in the city center, members of the National Guard are flooding the city, and a metal fence is being erected around the Capitol grounds prior to the swearing-in of President-elect Joseph R. Biden Jr.

Mr. Beeler of Front Royal, Virginia, drove to a security checkpoint less than half a mile from the Capitol compound on Friday evening and produced “an unauthorized personal induction badge” according to a statement from a Capitol police officer filed in a District court of Columbia on Saturday. The officer, Roger Dupont, said he checked the ID against a list and found that Mr Beeler was not allowed to enter the restricted area.

Officers searched his truck, which had several weapon-related bumper stickers, and found a loaded Glock pistol, 509 cartridges for the pistol, and 21 shotgun shells, police said. Mr Beeler had admitted having the Glock in the center console of the truck when asked if there were guns in the car, they said.

Mr. Beeler has been charged with five crimes, including possession of a gun and ammunition in Washington without proper registration. He and his lawyer did not respond to requests for comment on Saturday, but in his interview with The Post, Mr Beeler denied having 500 rounds of ammunition.

In an interview, Paul Beeler said Mr Beeler’s father, his son, a father of four, had been doing security near the Capitol grounds for the past few days and had other security duties in Washington over the years. Mr. Beeler has an active private security license in Virginia and is licensed to carry firearms while in use there, according to a state website.

“He was proud of the work he did with the police and the National Guard,” said his father. When asked if he believed his son would support a peaceful transfer of power, he said, “That’s why he’s there.”

The elder Beeler said he became concerned when his son didn’t return text messages on Friday night and called him Saturday morning thinking his son would be returning to Virginia after his shift. He and his wife discovered that Mr Beeler had been arrested when they received a call from a reporter, he said.

Police officials said they were alarmed by the chatter from far-right groups and other racist extremists threatening to target the nation’s capital to protest Mr Biden’s election victory. Federal authorities tried to prevent some people who violated the Capitol with weapons earlier this month from returning to the city, including by restricting their ability to board commercial aircraft, according to an administrative official.

For security reasons, Mr Biden has resisted requests to move the inauguration ceremony inside. His inauguration committee had already planned a reduced celebration with virtual components because of the corona virus.

Categories
World News

UK man makes last-ditch effort to get better misplaced bitcoin onerous drive

The reflection of bitcoins on a computer hard drive.

Thomas Trutschel | Photo library via Getty Images

LONDON – A British man who accidentally threw away a hard drive containing a lot of Bitcoin, again urges local city officials to have him look for it in a landfill.

James Howells, a 35-year-old IT engineer from Newport, Wales, said he threw the device away when he cleared his house in 2013. He claims he has two identical laptop hard drives and wrongly needed the one with the cryptographic “private key” to access his bitcoins and spend them in the trash.

After all these years, Howells is still confident that he can get the bitcoin back. Although the outer part of the hard drive could be damaged and rusted, he believes the hard drive inside could still be intact.

“There’s a good chance the disk in the drive is still intact,” he told CNBC. “Data recovery experts could then rebuild the drive or read the data directly from the platter.”

Howells says he has 7,500 bitcoins, which at today’s prices would be worth more than $ 280 million. He says the only way to get it back is by using the hard drive that he threw in the trash eight years ago.

But he needs permission from his local council to search a dump that he believes contains the lost hardware. The landfill is not open to the public and entering it is considered a criminal offense.

Howells has offered to donate 25% of the shipment, valued at around $ 70.8 million, to a Covid Relief Fund for his hometown if he can dig up the hard drive. He has also promised to fund the excavation project with the support of an undisclosed hedge fund.

However, Newport City Council has so far denied its search requests, citing environmental and financial concerns. And it doesn’t seem like local officials will budge anytime soon.

“As far as I know, they have already turned down the offer,” Howells said. “Without even hearing our plan of action or having the opportunity to present our mitigation of their environmental concerns, it’s just a resounding no every time.”

A spokesman for the council told CNBC that it had “been contacted several times since 2013 to investigate the possibility of retrieving a piece of IT hardware believed to contain bitcoins.” The first time “several months” after Howells first discovered the drive was gone.

“The council has told Mr Howells on several occasions that excavations are not possible under our permit and that excavations themselves would have a huge impact on the environment in the area,” said the council spokesman.

“The cost of digging the landfill, storing and treating the waste could run into millions of pounds with no guarantees that it will be found or that it will still work.”

It’s not hard to imagine why Howells would want to save the equipment. Bitcoin prices have skyrocketed in the last few months, hitting an all-time high near $ 42,000 last week before falling sharply.

The New York Times reported Tuesday that a programmer in San Francisco was banned from 7,002 bitcoins – valued at around $ 267.8 million today – for forgetting the password used to unlock a small hard drive with the private one Key to a digital wallet was required.

Bitcoin’s network is decentralized, which means that it is not controlled by a single person but by a computer network. Every transaction comes from a wallet with a “private key”. This is a digital signature and provides mathematical proof that the transaction came from the owner of the wallet.

Categories
Health

Want a New Knee or Hip? A Robotic Might Assist Set up It

“When I started practicing 30 years ago, if someone had hip pain we would take an x-ray, and even if they had arthritis and were in their forties, we told them to change their activity and wait,” he told Dr . William Maloney, professor of orthopedic surgery at Stanford University.

No longer. “The technology has fulfilled our patients’ desire to stay active,” he said.

One of the greatest innovations came in the late 1990s and early 2000s – just in time for the marathon runners who play tennis and play tennis to show signs of wear and tear.

“The industry has found a way to make the implants better,” said Robert Cohen, president of digital, robotic and activation technologies at Stryker’s orthopedic joint replacement division in Mahwah, New Jersey. and subject it to a post process of heat and radiation that made it even stronger. “

The implants made of “highly cross-linked polyethylene” significantly reduced the need for revision surgery. “One of the main reasons for the revision was the breakdown of polyethylene in the replacement compound,” he said.

Thanks to the advent of the stronger and more durable material, he says, “We’ve all but eliminated that.”

The new implants also contributed to faster recovery times.

“When I was a resident, people were hospitalized for 10 days after a total hip or knee,” said Dr. Dorothy Scarpinato in Melville, NY. “Now they’ll bring her out in a day or two.” As a result, she added, “People are no longer as afraid of this operation as they used to be.”

Some of the factors that contribute to shorter hospital stays, according to Dr. Maloney less invasive surgery, accelerated rehabilitation protocols, better pain management methods and the use of regional as opposed to general anesthesia.

Categories
Business

With Vaccines Arriving, Worth Traders Strive for a Comeback

Bill Nygren, vice president of Oakmark Funds, says his firm holds shares in CBRE, an office leasing company that he expects to appreciate in an economic recovery. Office work, he says, will recover. “Any company with a differentiated culture that believes they can remotely keep it alive is wrong,” said Nygren.

At the same time, like some other value investors, Mr. Nygren has bought stocks that, by most definitions, are on the growth side rather than the value side of the stock spectrum. The three largest holdings in the Oakmark mutual fund are Alphabet, Facebook, and Netflix, which make up just over 11 percent of its portfolio.

“People say a growing company can’t be a value stock,” said Nygren. “But to us, a value stock means that the stock sells for less than the deal is worth.” Netflix’s rapidly growing subscriber base is more valuable than conventional metrics such as price-to-book values ​​would suggest.

Comcast is one of the largest holdings in the Dodge and Cox Stock Fund, which highlights high capital value stocks, said Charles Pohl, chairman and chief investment officer of Dodge and Cox. While Comcast’s traditional television business faces stiff competition from online competitors such as Netflix, the company is successful in providing high-speed Internet services to customers and should benefit from a broad economic recovery.

He is also confident that financial stocks will recover with the economy. As of September 30, the fund held shares in Capital One, Charles Schwab, Bank of America and Wells Fargo, and financial stocks should lose value as the economy recovers.

Steve Watson, Portfolio Manager at Capital Group, who works for the American Funds Capital Income Builder, among others, said: “If we look at the world again, the market will look across the valley to the other side. “” He pointed to Total, the French oil company, as one of the stocks that would return when the world returned. And he noted that chemical company Dow’s shares rose sharply late in the year “because it is a company with a broad portfolio of chemical products that will help the global economy recover.”

In his view, value stocks were wrongly “knocked down”. “The market has been overwhelmed by growth,” he said.

Categories
Entertainment

‘Surprise Girl 1984’ | Anatomy of a Scene

I am Patty Jenkins. I’m the director of Wonder Woman 1984. “” We need the police here now! ” So this is a scene that we enjoyed so much. It is the first scene in the film that takes place today. The only thing we’ve seen in advance is a look back. And the first scene where we see Wonder Woman as an adult in our film. “What you are doing?” What was most important to me about this scene was that when I was thinking about what we were going to do with the second film, I realized that we wanted to say something much more serious and important than we were saying with the first film. So the immediate thing is, how do you do this and reach the audience that is most important to reaching out with this type of message? Which is the youth audience. It is the heroes of tomorrow who want to inspire you. We wanted to have a fun and engaging playful scene right away, and I’m really excited to be with kids and watch them see that scene. I also longed to see Wonder Woman at the peak of her powers and have a good time to save the day without effort. It’s something I love in so many superhero films. “We won’t do that today.” Where they are only on top of the world and you watch how they take care of everything. Another thing was the 80s of everything. Lynda Carter’s Wonder Woman was such a big moment for Wonder Woman and her story in the world and a big moment for me because that is exactly what I saw as a kid. Playing with that version of Wonder Woman that we hadn’t touched on in the first film made me realize that I wanted to do it in the first place because our story wouldn’t allow it. I have a lot more of it because I’m always with myself deal with the main character’s point of view. Of course, she gets into trouble right away and can’t just let go and have fun. It was a great thing to get into the 80s, but also to use new technology. All of these things, including this setting where these human bodies slam and Wonder Woman jumping over the barrier and flying through the air. 100% real, no digidouble, no special effect to achieve this. This was all wire work that we could design and engineer to get every single move there because no one has ever tried to do something like that in a real place. That was an amazing challenge, great craftsmen, and my great second unit director Dan Bradley, my great stunt coordinator Rob Inch. We just had amazing people working on it and making these magical things possible. And of course my cast here made it a sheer delight. [SIRENS]