Categories
Health

GPS monitoring, precedence touchdown for coronavirus vaccines, FedEx, UPS say

Wesley Wheeler, President of Global Healthcare at United Parcel Service (UPS), holds up a sample of the vial used to ship the Pfizer COVID-19 vaccine, as presented during a hearing of the Subcommittee on Commerce, Science and Transportation of the Senate testifies on logistics for shipping a COVID-19 vaccine on December 10, 2020 in Washington, DC.

Samuel Corum | Getty Images

Location tracking and priority flights are among the special treatments FedEx and United Parcel Service are planning to deliver coronavirus vaccines, executives said Thursday.

The shipping giants told a Senate transportation subcommittee that even when the busiest shipping season peaks during the holiday season, vaccines will be given priority over all other items. Richard Smith, executive vice president of FedEx Express, said the company is calling it the “Shipathon.”

Smith and Wes Wheeler, president of UPS Global Healthcare, expressed confidence that their companies could get the vaccines to administrative centers in the US and explained how they plan to divide the work.

Your comments come as federal health officials appear to be on the verge of deciding whether to accelerate approvals for Pfizer’s Covid-19 vaccine.

“Just to point out how deep this is, you have two strong rivals … in FedEx and UPS who are literally joining forces to make this happen,” said Smith. UPS also supplies materials for the vaccine kits such as diluents, syringes, and protective equipment for the medical personnel who administer the shots.

According to Wheeler from UPS, vaccine and dry ice shipments – Pfizer’s vaccine must be stored at minus 94 degrees Fahrenheit – will each have special labels with tracking technology. Vaccine shipments are also transported using devices that monitor temperature, location and movement.

He added that vaccines are loaded first and unloaded first on UPS planes. Executives said they are working with the Federal Aviation Administration to alert them to airplanes carrying the vaccine so that they can get priority take-off and landing permits.

“We are in constant communication with the aviation industry on daily command center calls and weekly calls with industry executives,” the FAA said in a statement. “We’re working with the industry to identify priority flights and prioritize our resources to meet the greatest demand.”

Categories
Business

Covid pandemic drove a file drop in international carbon emissions in 2020

The empty Champs Elysees avenue is pictured in Paris, France on March 28, 2020. The country has fined people who violate its statewide lockdown measures to stop the spread of COVID-19.

Pascal Le Segretain | Getty Images

Global greenhouse gas emissions have decreased by around 2.4 billion tons this year, a 7% decrease from 2019 and the largest decrease in history triggered by global Covid-19 restrictions. This is the result of new research from the University of East Anglia, the University of Exeter and the University of East Anglia, the Global Carbon Project.

The researchers said carbon emissions are likely to rise again in 2021, and urged governments to prioritize a shift to clean energy and action to combat climate change in their recovery plans.

Daily global carbon emissions fell 17% during the peak of the pandemic lockdowns in April, but have since risen again, approaching 2019 levels, according to the report published Thursday in Earth System Science Data.

“All the elements to sustainably reduce global emissions are not yet in place, and emissions are slowly falling back to 2019 levels,” Corinne Le Quere, professor at the UEA’s School of Environmental Sciences, said in a statement.

“Government action to stimulate the economy at the end of the Covid-19 pandemic can also help cut emissions and combat climate change,” she added.

The US saw the largest drop in CO2 emissions at 12%, followed by the European Union at 11%, the report said. In both cases, pandemic restrictions accelerated the decline in the use of coal in power generation and oil in transportation.

In developing countries, CO2 emissions fell by 9% in India, but only by 1.7% in China. China’s lockdown took place earlier in the year and was shorter in duration. In addition to the country’s rising CO2 emissions, there have been restrictions on CO2 emissions.

A decline in transport activity led to a global decrease in CO2 emissions. Emissions from automobiles and air travel fell by about half during the peak of Covid restrictions in April, and by December they were down about 10% and 40%, respectively, from 2019, according to the report.

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“Incentives that help accelerate the use of electric cars and renewables and encourage walking and cycling in cities are particularly timely given the significant disruption seen in the transport sector this year,” said Le Quere.

The historical decline in global emissions has also had a negligible impact on the levels of carbon in the atmosphere, which are warming the earth and worsening climate catastrophes, melting ice, and rising sea levels.

In 2020 alone, forest fires caused by climate change burned a record amount of land in the western United States, and the most active hurricane season in the Atlantic ravaged Central America and the Gulf Coast states.

“The climate system is powered by the total amount of CO2 that has been released into the atmosphere over centuries,” said Glen Peters, Research Director of International Climate Research in Norway and a member of the Global Carbon Project.

“Although emissions decreased in 2020, they were still at 2012 levels and the decrease is insignificant compared to the total amount of CO2 emitted over the past few centuries,” he said.

While global carbon emissions have steadily increased over the past few decades, researchers have found that emissions growth has increased more slowly in recent years, mainly due to changes in coal production.

“Global warming stops when emissions go to zero and Covid-19 hasn’t changed that,” Peters said.

Categories
Entertainment

‘Star Wars,’ ‘Pinocchio’ and Extra as Disney Leans Sharply Into Streaming

But there are huge challenges ahead of us. Streaming services are immensely expensive to build, and Disney now has four: Disney +, Hulu (39 million subscribers), ESPN + (11.5 million), and Star +, an overseas version of Hulu that will be available in the coming months is introduced in Latin America. Disney’s direct customer business losses were $ 2.8 billion in fiscal 2020. The company has ditched billions in royalties for amassing library content on Disney + instead of selling it to outside companies like Netflix.

Disney is also facing an increasingly competitive streaming environment. HBO Max, CBS All Access (soon to be renamed Paramount +), Peacock, Apple TV +, and the recently announced Discovery + are determined to keep moving forward. Netflix and Amazon continue to invest billions of dollars annually in the original programming.

A significant portion of the presentation was dedicated to Star, which will feature programs from Disney real estate such as ABC, FX, Freeform, Searchlight and 20th Century Studios, which Rupert Murdoch sold to Disney last year. In Latin America, Star + will be launched as a standalone service in June and will also include ESPN coverage of sporting events. In Europe, Canada, Australia and several other markets, Star + is being integrated directly into Disney +, adding a variety of more sophisticated programming to the service (“Deadpool 2”, the animated series “Family Guy”) that Disney potentially has an audience reach far beyond families.

The addition of a Star channel in Disney + also justifies a price hike of around 28 percent to around $ 11 per month.

New shows are also being routed to Disney’s Hulu, including the series “Nine Perfect Strangers,” a David E. Kelley puzzle starring Regina Hall, Nicole Kidman and Melissa McCarthy – which Dana Walden, chairwoman of entertainment at Walt Disney Television, called “juicy content that can’t be turned off”. Disney-owned FX, which broadcasts its programs on several Disney streaming services, is working with one on a TV spin-off of the film franchise “Alien” and a retelling of “Shogun”, the James Clavell saga half a dozen other highs profile projects.

During the presentation, Disney discussed its evolving approach to film distribution. The coronavirus pandemic has forced Disney and other studios to cut back on the release of big budget movies – more than half of US cinemas are closed – and redirect others to streaming services. In September, Disney debuted “Mulan” on Disney + as part of a “Premium Access” experiment and billed subscribers $ 30 for perpetual access. Pixar’s latest film, Soul, will be released on Disney + on Christmas Day at no additional cost.

Categories
World News

Covid-19 Information: Reside Updates – The New York Occasions

Here’s what you need to know:

Credit…Steve Helber/Associated Press

Pennsylvania announced statewide restrictions on Thursday that ban indoor dining and close gyms, theaters and casinos for three weeks to stem a “dire” surge in coronavirus cases, and Virginians were asked to stay home from midnight to 5 a.m. until the new year.

The clampdowns came as states across the country reported deaths and cases in numbers never seen before, and hospitals filled beyond capacity. Through Wednesday, there were seven-day records in both cases and deaths.

In Pennsylvania, Gov. Tom Wolf was unsparing Thursday in his characterization of the threat facing his state.

“This virus continues to rage in Pennsylvania,” Mr. Wolf said at a news conference. “Clearly we need to take future mitigation actions and stop the spread of Covid-19. We all hoped it would not come to this. The current state of the surge in Pennsylvania will not allow us to wait.”

And in Virginia, Gov. Ralph Northam announced a new executive order that imposes a nightly curfew, but it was unclear how — and how vigorously — it would be enforced.

The order lists categories of activity that will still be permitted during the curfew, including obtaining food, goods or services; seeking medical or law enforcement help; taking care of people or animals; child care; exercise; traveling to work, school or a house of worship; volunteering for charity; and leaving home to seek safety.

The governor urged residents not to go out without good reason. “We need to take this seriously,” Mr. Northam said. “We need to stay at home.”

But asked how the curfew would be enforced, the governor said it was “about messaging.”

Virginia reported at least 21 new coronavirus deaths and 4,398 new cases on Wednesday. Over the past week, the state has reported an average of 3,521 cases a day, an increase of 41 percent from the average two weeks earlier.

The new order also prohibits all public and private in-person gatherings of more than 10 people who do not live together, with exceptions for work and education, and requires people to wear masks “if they are in an indoor setting shared by others.” The state already requires masks outdoors.

Oklahoma also limited indoor activity, restricting indoor youth sporting events and public gatherings — which includes weddings, funerals and holiday parties held at event centers — to 50 percent capacity for the next 30 days. Places of worship are excluded.

On Wednesday, Pennsylvania reported 8,626 new cases and an additional 247 coronavirus deaths. The daily average over the past week has hovered near 10,000 cases per day, an increase of 51 percent from the average two weeks earlier.

Dr. Jaewon Ryu, the president and chief executive officer of Geisinger Health System, a regional hospital system, said the network was “operating pretty close to 100 percent capacity.”

Mr. Wolf, who announced on Wednesday that he had tested positive for the coronavirus and would be performing his duties remotely, said he was feeling well and that he had tested negative on Thursday. Mr. Wolf’s wife, Francis Wolf, also tested negative.

It was not immediately clear what type of test Mr. Wolf took, or if he had previously felt sick. Some types of coronavirus tests are prone to delivering incorrect results, especially when they are taken by people who are not experiencing symptoms.

Even before Governor Wolf issued his new order, the Pennsylvania House majority leader, Kerry Benninghoff, a Republican, pushed back against what many suspected was coming.

“Governor Wolf, do not cancel Christmas,” Mr. Benninghoff said in a statement. “Do not use your executive order pen to devastate lives and livelihoods. Government mandates will not cure COVID-19 and unilateral shutdowns will not create personal responsibility.”

In Virginia, speaking on the first night of Hanukkah, the governor also called on citizens to remember service members and essential workers during the holiday season.

“I know that Christmas and Hanukkah are truly cherished times,” he said. “The holidays look a bit different this year, and some of the traditions we treasure just aren’t possible.”

But he added, “As we look ahead to a new year, I see reason for hope and optimism that in the coming months, things will be better.”

The Pfizer/BioNTech vaccine being administered at a London hospital this week.Credit…Pool photo by Victoria Jones

Pfizer’s Covid-19 vaccine passed a critical milestone on Thursday when a panel of experts formally recommended that the Food and Drug Administration authorize its use.

The F.D.A.’s vaccine advisory panel, composed of independent scientific experts, infectious disease doctors and statisticians, voted in favor of emergency authorization for people 16 and older.

Although the F.D.A. does not have to follow the advice of its advisory panel, it usually does, and it is likely to do so within days, giving health care workers and nursing home residents first priority to begin receiving the first shots early next week.

The agency may act as soon as Saturday, though officials cautioned that last-minute legal or bureaucratic requirements might delay an announcement.

With that formal blessing, the nation may finally begin to slow the spread of the virus just as infections and deaths surge, reaching a record of more than 3,000 daily deaths on Wednesday.

The initial shipment of 6.4 million doses will leave Pfizer warehouses within 24 hours of being cleared by the F.D.A., according to federal officials. About half of those doses will be sent across the country, and the other half will be reserved for the initial recipients to receive their second dose about three weeks later.

It is the beginning of a complex, monthslong distribution plan coordinated by federal and local health authorities, as well as large hospitals and pharmacy chains.

If successful, the vaccine campaign should help return a grieving and economically depressed country back to some semblance of normal.

“With the high efficacy and good safety profile shown for our vaccine, and the pandemic essentially out of control, vaccine introduction is an urgent need,” Kathrin Jansen, a senior vice president and the head of vaccine research and development at Pfizer, said at the meeting.

The recommendation vote caps a whirlwind year for Pfizer and its German partner BioNTech, which began working on the vaccine 11 months ago, shattering all speed records for vaccine development, which typically takes years.

The Pfizer vaccine has already been given to people in Bahrain and Britain. Canada approved it on Wednesday. A U.S. authorization for it is expected to be followed soon by one for Moderna’s vaccine, which uses similar technology and has also shown promising results in clinical trials.

Dr. Robert Redfield, director of the Centers for Disease Control and Prevention, testifying before Congress in September.Credit…Anna Moneymaker/The New York Times

The editor in chief of a weekly report from the Centers for Disease Control and Prevention has told House Democrats that she was ordered to destroy an email showing that Trump political appointees attempted to interfere with its publication — and that she believes the order came from Dr. Robert R. Redfield, the agency’s director.

The explosive allegation from Dr. Charlotte Kent, the editor of the C.D.C.’s Morbidity and Mortality Weekly Report — the so-called “holiest of the holy” of health reports — is contained in a letter that Representative James E. Clyburn of South Carolina, the No. 3 House Democrat, sent Thursday morning to Dr. Redfield and the health secretary, Alex M. Azar II.

The email in question, dated Aug. 8, was sent by Dr. Paul Alexander, then a senior H.H.S. adviser, Mr. Clyburn’s letter said. In it, Dr. Alexander demanded that the C.D.C. insert new language in a previously published scientific report on coronavirus risks to children, or “pull it down and stop all reports immediately.”

Dr. Kent was on vacation when it arrived; the request to delete the message, she told investigators, was passed on to her by the woman who was filling in for her. She considered the request “very unusual,” she said. And when she tried to comply, she discovered the email had already been deleted — but she told investigators she had “no idea” by whom.

Dr. Redfield has said that the scientific integrity of the M.M.W.R., as the reports are known, has never been compromised — a point he reiterated in a statement on Thursday. He did not deny the order to delete the email, but said he had “instructed C.D.C. staff to ignore” Mr. Alexander’s comments.

“As I testified before Congress, I am fully committed to maintaining the independence of the M.M.W.R., and I stand by that statement.” Dr. Redfield said.

A separate statement from the C.D.C.’s parent agency, the Department of Health and Human Services, called Mr. Clyburn’s letter “irresponsible” and said it mischaracterized Dr. Kent’s testimony. House Republicans then released excerpts from Dr. Kent’s testimony in which she said she was “very committed to maintaining the scientific integrity of the M.M. WR.,” and would never let anything interfere with that.

Mr. Clyburn, who leads a committee that is investigating political interference with the C.D.C., wrote that after Dr. Kent spoke to the panel on Monday, the Trump administration abruptly canceled four more interviews with top C.D.C. scientists and officials, a move the congressman said amounted to obstructing his investigation.

“I am deeply concerned that the Trump administration’s political meddling with the nation’s coronavirus response has put American lives at greater risk,” Mr. Clyburn wrote, “and that administration officials may have taken steps to conceal and destroy evidence of this dangerous conduct.”

He told Mr. Azar and Dr. Redfield that if theydid not produce documents requested by his panel by Dec. 15, he would subpoena the records.

The issue of political interference in the weekly reports burst into the news in September, when current and former senior health officials disclosed that H.H.S. political appointees had repeatedly asked the C.D.C. to revise, delay and even scuttle reports on the coronavirus that they believed were unflattering to President Trump.

One point of contention was the C.D.C.’s guidance on school openings.

Mr. Clyburn’s letter quoted Mr. Alexander’s email as saying: “C.D.C. tried to report as if once kids get together, there will be spread and this will impact school reopening. … Very misleading by C.D.C. and shame on them. Their aim is clear. … This is designed to hurt this Presidnet [sic] for their reasons which I am not interested in.”

Mr. Alexander was dismissed from the department in September.

The committee is now seeking to interview the four other C.D.C. officials whose appearances were canceled: Dr. Anne Schuchat, the principal deputy director; Nina Witkofsky, the acting chief of staff; Trey Moeller, the acting deputy chief of staff; and Kate Galatas, the acting associate director for communications.

Volunteers for coronavirus vaccine trials in Soweto, South Africa.Credit…Jerome Delay/Associated Press

Wealthy nations have a firm upper hand in securing a coronavirus vaccine compared with developing countries, a global coalition of organizations and activists warned on Wednesday.

In about 70 developing countries, only one in 10 residents is expected to receive a Covid-19 vaccine within the next year, according to the People’s Vaccine Alliance, which consists of organizations such as Amnesty International, Frontline AIDS, Global Justice Now and Oxfam.

“The hoarding of vaccines actively undermines global efforts to ensure that everyone, everywhere can be protected from Covid-19,” said Steve Cockburn, Amnesty International’s head of economic and social justice. “Rich countries have clear human rights obligations not only to refrain from actions that could harm access to vaccines elsewhere, but also to cooperate and provide assistance to countries that need it.”

Rich countries representing 14 percent of the global population have bought over 50 percent of promising Covid-19 vaccines, according to data collected by Airfinity, a London-based software company tracking deals between countries and manufacturers. It looked at supply deals that included eight vaccine candidates in Phase 3 clinical trials.

The alliance called on pharmaceutical companies along with researchers to “share the science, technological know-how and intellectual property” of their vaccines. They also asked governments to ensure their Covid-19 vaccines are free to the public and equitably available.

Recently, countries including South Africa and India have pushed for loosened restrictions on intellectual property rights for Covid-19 vaccines, proposing that the World Trade Organization end global enforcement of the rights in the interest of accessibility.

“Governments must also ensure the pharmaceutical industry puts people’s lives before profits,” said Heidi Chow, a senior campaign and policy manager at Global Justice Now.

Developing countries that the alliance focused on currently have access to the vaccine only through Covax, a global initiative to vaccinate much of the world population. (The United States declined to be a part of the effort.)

The United Kingdom started vaccinations this week, after becoming the first Western country to authorize a Covid-19 vaccine. On Wednesday, the United Arab Emirates approved China’s coronavirus vaccine, signaling a win for that country’s vaccine ambitions. Canada approved Pfizer and BioNTech’s coronavirus vaccine, which was also approved in Britain. Both Pfizer and Moderna have submitted their applications for emergency approvals the U.S. Food and Drug Administration and vaccinations in the U.S. could start before next month.

However, the news of vaccination success in wealthy nations hasn’t necessarily equated to access for developing countries: Wealthy nations have purchased enough doses to vaccinate their populations three times over by the end of 2021, the alliance said.

“By buying up the vast majority of the world’s vaccine supply, rich countries are in breach of their human rights obligations,” Mr. Cockburn said. “Instead, by working with others to share knowledge and scale up supply, they could help bring an end to the global Covid-19 crisis.”

Weekly initial jobless claims through the week ending Dec. 5

Pandemic Unemployment

Assistance claims

Jump in claims the week after Thanksgiving

Weekly initial jobless claims through the week ending Dec. 5

Pandemic Unemployment

Assistance claims

Jump in claims the week after Thanksgiving

Applications for jobless benefits resumed their upward march last week as the worsening pandemic continued to take a toll on the economy.

More than 947,000 workers filed new claims for state unemployment benefits last week, the Labor Department said Thursday. That was up nearly 229,000 from the week before, reversing a one-week dip that many economists attributed to the Thanksgiving holiday. Applications have now risen three times in the last four weeks, and are up nearly a quarter-million since the first week of November.

On a seasonally adjusted basis, the week’s figure was 853,000, an increase of 137,000.

Nearly 428,000 applied for Pandemic Unemployment Assistance, a federal program that covers freelancers, self-employed workers and others who don’t qualify for regular state benefits.

Unemployment filings have fallen greatly since last spring, when as many as six million people a week applied for state benefits. But progress had stalled even before the recent increases, and with Covid-19 cases soaring and states reimposing restrictions on consumers and businesses, economists fear that layoffs could surge again.

“It’s very clear the third wave of the pandemic is causing businesses to have to lay people off and consumers to cut back spending,” said Daniel Zhao, senior economist for the career site Glassdoor. “It seems like we’re in for a rough winter economically.”

Jobless claims rose in nearly every state last week. In California, where the state has imposed strict new limits on many businesses, applications jumped by 47,000, more than reversing the state’s Thanksgiving-week decline.

The monthly jobs report released on Friday showed that hiring slowed sharply in early November and that some of the sectors most exposed to the pandemic, like restaurants and retailers, cut jobs for the first time since the spring. More up-to-date data from private sources suggests that the slowdown has continued or deepened since the November survey was conducted.

“Every month, we’re just seeing the pace of the recovery get slower and slower,” said AnnElizabeth Konkel, an economist with the job site Indeed. Now, she said, the question is, “Are we actually going to see it slide backward?”

Many economists say the recovery will continue to slow if the government does not provide more aid to households and businesses. After months of gridlock in Washington, prospects for a new round of federal help have grown in recent days, with congressional leaders from both parties signaling their openness to a compromise and the White House proposing its own $916 billion spending plan on Tuesday. But the two sides remain far apart on key issues.

The stakes are particularly high for jobless workers depending on federal programs that have expanded and extended unemployment benefits during the pandemic. Those programs expire later this month, potentially leaving millions of families with no income during what epidemiologists warn could be some of the pandemic’s worst months.

Richard Hinch was elected speaker of the New Hampshire House of Representatives at an outdoor meeting Dec. 2. He died a week later.Credit…Elise Amendola/Associated Press

The New Hampshire State Legislature was already fiercely divided over the coronavirus when the new Republican speaker of the House of Representatives, Richard Hinch, died suddenly on Wednesday. Then came the news on Thursday that the cause of his death was Covid-19.

Mr. Hinch, who was 71, died just a week after he was sworn in as speaker — and about three weeks after an indoor meeting of his caucus that led to several members contracting the virus, an event that Mr. Hinch had tried to play down in public remarks. It was not clear whether he, too, had caught the virus at the caucus meeting.

The news will undoubtedly heighten tensions among state lawmakers, who have been at odds over the refusal of many Republican lawmakers to wear masks or take other pandemic precautions seriously. Splits have opened not just along partisan lines but also within the Republican ranks.

William M. Marsh, a Republican state representative, said the responsibility for Mr. Hinch’s death lies on the shoulders of a group of Republican members who refused to take precautions like wearing masks and maintaining social distance, and who leaned on others to do the same. “The peer pressure from colleagues is the root cause of what happened to my friend,” Mr. Marsh said of Mr. Hinch.

Democratic lawmakers, who held a majority before the Nov. 3 election, have been in an uproar over the Republican caucus meeting, which was held on Nov. 20 at a ski area. Democrats say they were kept in the dark about the infected lawmakers while Republicans were informed.

The Democratic former speaker, Steve Shurtleff, said he was troubled by Mr. Hinch’s support of Republican lawmakers who refused to wear masks on the House floor, whom Mr. Hinch had called the “patriot section” and the “freedom group.”

“It’s so ironic, looking back,” Mr. Shurtleff said on Thursday. “I know he was just doing his job as a Republican leader, defending his members and his caucus, but it seems so senseless now.”

Mr. Shurtleff said he hoped that the acting speaker would arrange for the House to meet remotely when its next session convenes in January, because he did not expect the mask-resistant Republicans to change their behavior. “I don’t think there will be any remorse,” he said. “There may be remorse at his passing, but not so much at the cause.”

Gov. Chris Sununu, a Republican, said on Wednesday that Mr. Hinch was “a fierce defender” of the state, “a close friend and a respected public servant.” He, too, was critical of lawmakers who refuse to wear masks. “For those who are out there doing just the opposite, just to make some sort of bizarre political point, it’s horribly irresponsible,” he said. “Use your heads, don’t act like a bunch of children.”

The State Senate and House each held their organizational meetings outdoors in 40-degree weather last week. About 130 members of the 400-seat House did not attend in person and were sworn in remotely, according to The Associated Press.

Republican lawmakers in at least two other states where mask wearing and other restrictions have been politically contentious have tested positive in recent days:

  • A South Dakota state senator who attended a dinner with the governor on Monday, and then joined dozens of lawmakers for a budget speech on Tuesday, tested positive on Wednesday. Senator Helene Duhamel of Rapid City posed for a group photo, shoulder to shoulder with Gov. Kristi Noem and more than two dozen other women who attended the dinner. Governor Noem has fiercely resisted imposing a mask mandate or any other restrictions throughout the pandemic, even as the coronavirus raged through the state in the fall, overwhelming its hospitals. The governor’s office insisted that she had not had close contact with Ms. Duhamel, even though they were photographed standing only a few feet apart.

  • The chairman of the appropriations committee in the North Dakota State Senate, Ray Holmberg, confirmed to The Bismarck Tribune on Thursday that he had tested positive, and said he believed he was infected with the virus during the legislature’s organizational session last week. Three employees of the legislature’s nonpartisan research agency have also tested positive, The Associated Press reported.

Ellen DeGeneres announced in a tweet on Thursday that she had tested positive for the coronavirus.Credit…Chris Pizzello/Invision, via Associated Press

“The Ellen DeGeneres Show” has paused filming after its host said on Thursday that she had tested positive for the coronavirus.

“Fortunately, I’m feeling fine right now,’’ Ms. DeGeneres wrote in a statement she posted to Twitter.

Ms. DeGeneres said that anyone who had been in close contact with her had been notified, and that she was following guidelines from the Centers for Disease Control and Prevention.

“I’ll see you all again after the holidays,’’ she wrote. “Please stay healthy and safe.’’

The production company Telepictures, which is a unit of Warner Bros. Television, said in a statement that it had paused filming until January.

The talk show, which films in Burbank, Calif., has been a staple of daytime television since 2003.

After shifting to virtual audiences amid the pandemic, Ms. DeGeneres had resumed filming with a limited live audience in late October. Attendees were required to wear face masks and sit six feet apart.

Ms. DeGeneres had faced accusations of leading a toxic workplace earlier this year, after BuzzFeed News published an article in July in which former staff members said they faced “racism, fear and intimidation” on set. Warner Bros. announced an investigation, three producers left the show, and Ms. DeGeneres apologized on camera and to employees.

The European Medicines Agency, located in Amsterdam, did not disclose who was behind the cyberattack.Credit…Remko De Waal/EPA, via Shutterstock

The European Medicines Agency, the European Union’s top drug regulator, whose approval is necessary for countries in the bloc to begin rolling out the coronavirus vaccine, has begun an investigation after it was hit by a cyberattack, it said on Wednesday.

The agency, which is reviewing vaccine candidates, did not provide details about the target or the date of the attack. But shortly after the announcement, Pfizer and BioNTech said in their own statement that some documents related to the regulatory submission of their vaccine and which were hosted on a server of the European agency, had been “unlawfully accessed.”

Pfizer and BioNTech said their systems had not been breached, and that no study participants appeared to have been identified as a result of the cyberattack.

The breach comes at a time of heightened threats faced by pharmaceutical companies, health care institutions and agencies involved in the production, approval and distribution of the vaccine.

Last week, IBM said it had detected a series of cyberattacks in September against companies involved in the distribution of coronavirus vaccines across the world and against a branch of the European Commission, the E.U.’s executive arm.

The European Medicines Agency is set to announce a decision on the Pfizer/BioNTech vaccine by Dec. 29. Although each country in the bloc will be in charge of its own rollout, the agency’s approval will pave the way for the largest vaccination campaign in the West, dwarfing the rollout that started this week in Britain and most likely posing more considerable logistical and security challenges.

Canada approved the Pfizer/BioNTech vaccine on Wednesday, becoming the second Western country to do so. Russia began the rollout of its own Sputnik 5 vaccine on Saturday.

The European Medicines Agency didn’t disclose who was behind the cyberattack, saying that it “cannot provide additional details whilst the investigation is ongoing.” Pfizer and BioNTech said in their statement that they were awaiting further information from the agency.

Cybersecurity experts have said that only state actors could carry out such operations. Microsoft revealed last month that hacker groups backed by Russia and North Korea had targeted several vaccine makers in the United States, Canada and France, among other countries.

“The intentions behind those attacks are to parasite Western efforts on the vaccine,” said Julien Nocetti, a researcher at the French Institute of International Relations who studies cybersecurity with a focus on Russian activities.

By breaking into the system of key actors involved in the vaccine or by disrupting distribution efforts, attackers could exact considerable damage, said Claire Zaboeva, a senior cyberthreat analyst at IBM’s Security X-Force.

Ms. Zaboeva said about the production and delivery of the vaccine: “If you manage to get the key to the whole kingdom, you have 500 options on the menu: collecting key timetables, which nations will get the vaccine, how it will get there, what companies will be associated with the delivery, or how it will be handled.”

Healthcare workers and the Connecticut National Guard administering coronavirus tests in Stamford, Conn., on Wednesday.Credit…Dave Sanders for The New York Times

Months into the pandemic, many people still are frustrated and confused about virus testing.

Long lines at testing sites, delays in getting results and even surprise testing bills have discouraged some people from getting tested.

And many people don’t understand what a test can and can’t tell you about your risk, and wrongly think a test result that comes back negative guarantees they can’t spread the virus to others.

We asked some of the nation’s leading experts on testing to help answer common questions about how to get tested, what to expect and what the different tests and results really mean.

Among them:

  • When should be people be tested?

  • What are the tests like?

  • What type of test should people get?

  • And how do you interpret the results?

Airlines are just one piece of a massive global machine cranking up to tackle one of the biggest logistical challenges in recent memory.Credit…Kriston Jae Bethel for The New York Times

Months before anyone knew which of the coronavirus vaccine candidates would pull ahead or when they’d be available, airlines were trying to figure out how to transport doses around the world.

Over the summer, American Airlines, Delta Air Lines and United Airlines spoke with government officials, pharmaceutical companies and experts to understand where vaccines might be produced, how they would be shipped and how best to position people and planes to get them moving. More recently, they have flown batches of vaccines for use in trials and research or to prepare for wider distribution.

The industry will play a vital role in moving billions of doses in the months ahead, putting underused planes and crews to work while circulating the very medicine that airlines hope will get people to book tickets again.

“When a request comes in, it’s going to be urgent and we have to act immediately,” said Manu Jacobs, who oversees shipments of pharmaceuticals and other specialty products for United.

One of the biggest challenges for airlines has been ensuring that vaccines are transported at frigid temperatures. Pfizer’s must be stored at an incredibly low minus-94 degrees Fahrenheit. Moderna’s can be kept at a more easily managed minus-4 degrees.

For its vaccine, Pfizer designed special cooler containers that can be stuffed with dry ice, which is solid carbon dioxide. But aviation authorities limit how much dry ice can be carried on planes because it turns to gas, making the air potentially toxic for pilots and crews.

After running tests that showed it was safe, United last month asked the Federal Aviation Administration to raise the limit so it could fly the Pfizer vaccine from Brussels International Airport to Chicago O’Hare International Airport, according to an F.A.A. letter. The agency allowed the airline to carry up to 15,000 pounds of dry ice aboard a Boeing 777-224 plane, compared to the previous limit of 3,000 pounds, according to the letter. A single 777 can carry up to one million doses, the airline said.

In normal times, about half of all air cargo is transported by airlines, often beneath the feet of passengers. The steep decline in flights this spring removed much of that capacity, but the urgent need for masks, gloves and ventilators created a big opportunity for cash-starved carriers, allowing them to recapture at least some of that lost business.

Quarantine orders for the passenger’s close contacts aboard the ship were rescinded after he tested negative.Credit…Edgar Su/Reuters

An 83-year-old passenger who initially tested positive for the coronavirus on a “cruise to nowhere” from Singapore this week, forcing thousands of passengers and crew members to return to port a day early, did not have the virus after all, officials said on Thursday.

The passenger, who had diarrhea aboard the ship Quantum of the Seas and had taken a mandatory Covid-19 test, has since tested negative several times, Singapore’s Ministry of Health said in a statement.

“The sample taken from the individual this morning came back negative for the virus,” officials said on Thursday. It was the third negative test after two on Wednesday also came back negative.

Quarantine orders for the man’s close contacts and other passengers aboard the ship were then rescinded, the ministry said.

Singapore’s Tourism Board said that contact tracing began immediately after the man’s positive test and that all leisure activities on board were canceled. The ship’s captain had also ordered guests to remain in their cabins during the investigation.

Quantum of the Seas, which is owned by Royal Caribbean, returned to the Marina Bay Cruise Center in Singapore at 8 a.m. Wednesday. All remaining passengers and crew members were required to undergo mandatory testing upon disembarking, the tourism board said.

The board also asked that passengers monitor their health for 14 days and to undergo a swab test at a designated government center at the end of the monitoring period.

When the cruise left the city-state on Monday, all 1,680 passengers and 1,148 crew members had tested negative for Covid-19, according to the tourism board.

The incident underscores the uncertainties the global tourism industry, battered by the pandemic, faces as it struggles to restart. The cruise ship is one of two to operate out of Singapore this month while putting in place a long list of safety precautions to reassure passengers.

A New York Times reporter recently took a trip on the other one, the World Dream.

In February, the coronavirus infected more than 200 people board the Diamond Princess cruise ship, trapping its 3,600 passengers and crew. Governments later banned cruises, crews were sent home, and passengers canceled their bookings. But countries like Singapore, Japan and several in Europe have since allowed cruises to restart under the watchful eye of officials.

Dr. Vivek H. Murthy advised the N.C.A.A. Board of Governors in the early days of the coronavirus pandemic.Credit…Hilary Swift for The New York Times

President-elect Joseph R. Biden Jr.’s choice for surgeon general, Dr. Vivek H. Murthy, had a central role in the National Collegiate Athletic Association’s decision in March to cancel this year’s national basketball tournaments — one of the earliest and most culturally significant signs that the virus would upend ordinary life in America.

The work of Dr. Murthy, a member of the association’s powerful Board of Governors who was surgeon general during part of the Obama administration, offers a view into how he approached the pandemic’s initial threat in the United States, and how he might help shape the federal government’s response under Mr. Biden.

A newcomer to the insular world of college athletics, Dr. Murthy proved a cautious, deliberate expert who was wary of making drastic decisions prematurely, interviews with more than a dozen people who participated in the N.C.A.A.’s meetings suggest. But they said that as the tournaments approached and more data and scientific research emerged, Dr. Murthy was a forceful and effective champion of measures that had been unthinkable to most of society only days or weeks earlier.

Indeed, it was Dr. Murthy who urgently told board members that they risked fueling a deadly crisis if they allowed the tournaments to proceed as scheduled.

“He was instrumental in convincing the board that the time to act was now,” said Kenneth I. Chenault, a former chairman of American Express who sits on the N.C.A.A. board.

But board members like Mr. Chenault said that it was plain that Dr. Murthy understood the cultural and financial repercussions of a decision like canceling the basketball tournaments, which generate hundreds of millions of dollars.

GLOBAL ROUNDUP

A market in Seoul, South Korea, on Tuesday. Health officials warned that ​the number of coronavirus cases could rise to record highs in coming days.Credit…Kim Hong-Ji/Reuters

For most of the year, South Korea has kept its coronavirus numbers so low it was the envy of the world. Now, the country is grappling with the most elusive wave of infections it has seen, just as other nations prepare to roll out vaccinations.

South Korea’s daily number of new cases was once as low as two per day. That number soared to​ 682 on Thursday, with health officials warning it could reach record highs in coming days. On Wednesday​, 686 new cases were reported, the highest daily count since Feb. 29.

“We must exert all we can, considering this is our last hurdle to clear ​in our efforts to curb the coronavirus before vaccines and treatments come online,” President Moon Jae-in said this week. He has instructed his government to mobilize ​​soldiers​, police officers and civil servants ​to help epidemiologists’ contact-tracing efforts.

The country’s struggle to contain the recent surge is a race against time. Mr. Moon’s government announced this week that it had secured enough doses of coronavirus vaccines from companies like AstraZeneca and Pfizer to inoculate roughly 86 percent of the population, but that the first batch would not arrive until March.

South Korea has been hit by four waves of infections since its first case was reported in January. But the latest is by far the ​hardest to control, health officials said.

Previous waves included mass clusters that health officials were able to target and trace. The current wave spread through numerous small clusters that erupted in nursing homes, hospitals, saunas, bars, restaurants, music halls and factories, most of them in the Seoul metropolitan area, but also in towns farther away.

Daily cases continue to rise despite tightened social-distancing ​guidelines and other measures. Na Seong-woong, a deputy commissioner of the Korea Disease Control and Prevention Agency, warned that the daily caseload could surpass 900 next week.

“We are facing our biggest ever coronavirus crisis because the current wave is neither temporary nor regional, but steady and nationwide,” he said. “We don’t have one central cluster that we can shut down with a focused testing and isolating campaign, but it’s popping up here and there and everywhere through our daily lives.”

In other developments across the world:

  • Spain was hit far worse during the first wave of the coronavirus than official data showed at the time, according to new statistics published by Spain’s national statistics institute on Thursday. The institute said 45,684 people had died of Covid-19 between March and May, compared to the 27,127 dead that Spain’s health ministry had reported by May 31. The health ministry counts only deaths officially attributed to Covid-19, while the statistics institute counted those who died with the disease as the most likely cause.

  • Hospitals in Tokyo were strained as Japan’s capital city reported 602 new cases on Thursday, its first time topping 600 cases in a day, officials said. Government officials have recommended that residents avoid outings.

  • Pope Francis will hold midnight Mass in Rome two hours earlier on Christmas Eve than he has in previous years, beginning at 7:30 p.m. to comply with Italy’s 10 p.m. curfew. The pope will also give his annual Christmas Day blessing at noon from inside St. Peter’s Basilica instead of from the loggia, where thousands would usually gather.

  • Secondary school students in the seven worst-hit areas of London will be tested for the virus, Britain’s health secretary, Matt Hancock, said at a news conference on Thursday evening. Mr. Hancock said that group of students, which he described as being ages 11 to 18, is by far accounting for the fastest rise in cases, and that the virus rate among adults in London is “broadly flat.” He urged secondary school students to get tested regardless of whether they had symptoms and said more details on the plan would follow Friday. Mr. Hancock said with the vaccine now being administered in Britain, there is hope on the horizon. “So don’t blow it now.”

  • In New York City, Mayor Bill de Blasio outlined a plan on Thursday, without providing much specific detail, to help students recover from the educational disruption caused by the pandemic. “Clearly, there will be a Covid achievement gap, and we have to close that,” he said. The mayor noted several areas he would focus on before the start of the next school year in September: finding a baseline for the academic ground lost; developing digital content and a learning hub; expanding professional development; enlisting parents to help more in education; and helping students deal with mental health issues and trauma related to the pandemic.

The reopening of theaters, museums and cinemas in France will be delayed for another three weeks.Credit…Abdulmonam Eassa/Agence France-Presse — Getty Images

The French government on Thursday said that it will delay relaxing some Covid-19 lockdown restrictions because rates of new cases were not falling as fast as expected.

The reopening of theaters, museums and cinemas, which was planned for Dec. 15, will be pushed back another three weeks, and a curfew that will replace the current lockdown will run earlier than planned.

The authorities had announced that a reprieve from the restrictions would be implemented on the condition that France reached a target of 5,000 new cases per day and fewer than 3,000 Covid-19 patients in intensive care.

Although the target of 3,000 patients in intensive care is within sight, France on Wednesday reported about 15,000 new cases, dampening hopes that daily new cases could fall to 5,000 by next Tuesday.

“We are not yet at the end of this second wave and we will not reach the objectives we had set,” Prime Minister Jean Castex said at a news conference on Thursday.

“The battle is far from won,” he said, adding that although the health situation improved for the past few weeks, it has plateaued in recent days.

The health minister Olivier Véran said that “we know that from plateau to peak sometimes things can go very fast.”

France will stick to a previously announced plan to end the lockdown on Dec. 15 and replace it with a nightly curfew. But in a departure from the plan, the curfew will start one hour earlier, at 8 p.m., and will not be waived for New Year’s Eve.

An exception will be made for Dec. 24, Christmas Eve, when people will be allowed to move freely during the night.

“The risk is that if we don’t change anything, the second wave will start again in the next few weeks,” Mr. Véran said.

On Thursday, the French Senate released a scathing report of a parliamentary commission that dissected the government’s failures in its handling of the coronavirus crisis and denounced “late and uncoordinated decisions” that delayed the government’s response to the pandemic.

The report specifically pointed to the failure of the government’s management of critical stocks of face masks. “The shortage of masks will remain the unfortunate symbol of the unpreparedness of the country and the lack of anticipation of the health authorities in the face of the crisis,” the report said.

It pointed out that Jérome Salomon, a top official at the health ministry, chose not to replenish stocks of masks in 2018, despite being warned about risks of shortages, and lobbied to retrospectively amend a scientific report in order to justify this decision. In a statement sent on Thursday night, Mr. Salomon denied that any pressure was exerted on the authors of the report.

“The mask fiasco was deliberately concealed by the government during the crisis,” the report said, adding that “a communication crisis has undermined the credibility of public and scientific discourse, the effects of which will be lasting.”

The parliamentary commission added that France’s strategy to test, trace and isolate in order to prevent a second wave of the virus proved unsuccessful, because of backlogs of test results, a limited contact tracing operation and an almost nonexistent isolation strategy.

Mr. Castex did not comment on the report, but acknowledged that a sense of fatigue surrounding the pandemic was growing in the country.

“I know your weariness, your doubts, your suffering,” Mr. Castex said. “I share them.”

Staff aides to Senate Majority Leader Mitch McConnell warned that most Republicans are unlikely to support the bipartisan plan.Credit…Anna Moneymaker for The New York Times

Staff aides to Senator Mitch McConnell of Kentucky, the majority leader, have informed other congressional leaders that it is unlikely that the majority of Republicans could support compromise provisions addressing liability protections and state and local government funding in a $908 billion stimulus deal being hammered out by a bipartisan group of moderates.

Their warning reflected the deep resistance among several Republicans for another large round of federal relief. For months their reluctance has helped to stymie agreement on an economic recovery plan to help struggling businesses and individuals amid the pandemic. Mr. McConnell and Republicans have been particularly resistant to providing billions of dollars to cash-strapped state and local governments, a top Democratic priority that would receive $160 billion under the moderates’ emerging outline.

That package is likely to contain some form of limited liability protection to businesses, schools and hospitals, which most Democrats have dismissed as a nonstarter, but the shield could be temporary and not as sweeping as the one that Mr. McConnell has demanded, which prompted the private skepticism.

The potential Republican antipathy for the compromise that was conveyed by Mr. McConnell’s staff was first reported by Politico, and was relayed on condition of anonymity by a senior Democrat familiar with the conversation. Mr. McConnell’s office declined to comment.

“My view is that the best thing that could happen is the pieces of this that everybody agrees on, take that out — take the funding for state local governments out — and pass the rest of it,” Senator John Thune of South Dakota, the No. 2 Republican, told reporters, offering a suggestion Democrats have panned.”

The bipartisan group is still struggling to finalize its agreement, let alone produce legislation that could be voted on in the coming days.

With just a handful of days before the end of the 116th Congress and a number of critical programs established in previous coronavirus legislation set to expire, lawmakers agree that both chambers should not leave Washington until they reach consensus on both an omnibus government spending package and a pandemic aid deal.

The Senate is expected to approve a one-week stopgap bill before funding lapses on Friday, intended to buy additional time for negotiators on both issues. But the timing of the vote was unclear as of Thursday afternoon.

Top Democrats have signaled support for the bipartisan discussions, led by a handful of moderate lawmakers in both chambers, as a possible avenue for a final agreement. But in doing so, Democrats also rejected a proposal from Mr. McConnell to remove the provisions related to state and local government and liability protections and focus on approving funding for schools, education and small businesses.

Steven Mnuchin, the Treasury Secretary, presented Ms. Pelosi on Tuesday with a $916 billion alternative, but she and other Democrats rejected it given that it failed to revive lapsed federal supplemental jobless payments. Instead, it would include a round of $600 stimulus checks, half the amount initially approved earlier this year.

Categories
Business

Deb Worth, a First as a Columnist on Homosexual Life, Dies at 62

After stints at The Northern Virginia Sun and the States News Service, which covered Washington news for dozens of newspapers across the country, she joined the Washington Post in 1984. Both she and Ms. Murdoch were editors at the newspaper’s National Desk, and they became a couple in 1985.

They were the first to register as Domestic Affiliates in Takoma Park, Md., Where they lived, in 1993, and joined a civil union in Vermont in 2000. In 2003 they were finally able to legally marry in Toronto was the first same-sex wedding announcement that the Washington Post put on their wedding website.

“Enthusiastic tennis players, world travelers and certified divers, the newlyweds will be celebrating their honeymoon in Hawaii later this year,” the announcement said.

The couple produced two well-received books. “And say hello to Joyce, America’s First Gay Column Coming Out” (1995) garnered most of Ms. Price’s columns with comments from Ms. Murdoch. They dedicated it to “all gay readers who put 25 cents in a newspaper box and found nothing that reflects their own life”.

Her second was “Courting Justice: Gays and Lesbians v. The Supreme Court” (2001), described by a Kirkus reviewer as “a Crackerjack resource volume on gay legal history”.

Ms. Price continued her column until 2010 when she received a Nieman Fellowship to study at Harvard.

In Hong Kong, where the couple was moving when Ms. Murdoch was given an academic appointment there, Ms. Price, a long-time business and finance specialist, worked for the Asian Wall Street Journal. She became editor-in-chief of Caixin Global, an independent financial publication in China, and senior business editor at The South China Morning Post.

Mrs. Murdoch is her only immediate survivor. Ms. Price’s older brother Stephen died in 2018.

“We never had children,” said Ms. Murdoch. “We knew that our gay rights work would be our most important legacy.”

Categories
Health

F.D.A. Panel Provides Inexperienced Mild to Pfizer’s Covid Vaccine

Pfizer’s Covid-19 vaccine passed a critical milestone on Thursday when a panel of experts formally recommended that the Food and Drug Administration authorize the vaccine. The agency is likely to do so within days, giving health care workers and nursing home residents first priority to begin receiving the first shots early next week.

The F.D.A.’s vaccine advisory panel, composed of independent scientific experts, infectious disease doctors and statisticians, voted 17 to 4, with one member abstaining, in favor of emergency authorization for people 16 and older. With rare exceptions, the F.D.A. follows the advice of its advisory panels.

With this formal blessing, the nation may finally begin to slow the spread of the virus just as infections and deaths surge, reaching a record of more than 3,000 daily deaths on Wednesday. The F.D.A. is expected to grant an emergency use authorization on Saturday, according to people familiar with the agency’s planning, though they cautioned that last-minute legal or bureaucratic requirements could push the announcement to Sunday or later.

The initial shipment of 6.4 million doses will leave warehouses within 24 hours of being cleared by the F.D.A., according to federal officials. About half of those doses will be sent across the country, and the other half will be reserved for the initial recipients to receive their second dose about three weeks later.

The arrival of the first vaccines is the beginning of a complex, monthslong distribution plan coordinated by federal and local health authorities, as well as large hospitals and pharmacy chains, that if successful, will help return a grieving and economically depressed country back to some semblance of normal, maybe by summer.

“With the high efficacy and good safety profile shown for our vaccine, and the pandemic essentially out of control, vaccine introduction is an urgent need,” Kathrin Jansen, a senior vice president and the head of vaccine research and development at Pfizer, said at the meeting.

The vote caps a whirlwind year for Pfizer and its German partner BioNTech, which began working on the vaccine 11 months ago, shattering all speed records for vaccine development, which typically takes years. It is also a triumph for the F.D.A., which has upheld its reputation as the world’s gold standard for drug reviews despite months of political pressure from President Trump, who has sought to tie his political fortunes to the success of a vaccine. The Pfizer vaccine has already been given to people in Bahrain and Britain, where it was authorized on Dec. 2. Canada approved it on Wednesday.

The U.S. authorization of Pfizer’s vaccine is expected to be followed soon by one for Moderna’s version, which uses similar technology and has also shown promising results in clinical trials. Operation Warp Speed, the Trump administration’s multi-billion-dollar program to fast-track vaccine development, pre-ordered 100 million doses of Pfizer’s vaccine in July and heavily backed the development and manufacturing of Moderna’s vaccine.

More than 100 F.D.A. employees have worked nearly round the clock to review the application Pfizer submitted on Nov. 20, compressing months of analysis into weeks as they pored over thousands of pages of clinical trial and manufacturing data.

Earlier this week, career scientists at the F.D.A. published an analysis showing the vaccine worked across a variety of demographic groups and that it was somewhat effective even after the first of two doses.

During the daylong meeting on Thursday, panel members peppered company and agency experts with detailed questions about the safety and efficacy of the vaccine, which was found to be 95 percent effective in a late-stage clinical trial. Some members expressed concern that there was not enough data from 16- and 17-year-olds to know whether the vaccine would help them, but the committee decided the benefits for that group outweighed the risks.

Some members asked about the likelihood for serious allergic reactions, given the news that regulators in Britain recommended this week that people with a history of anaphylactic allergic reactions to medicines and foods not get the vaccine while they investigate two cases of allergic reactions among health care workers. Pfizer officials said there were no cases of serious allergic reactions in the trial of 44,000 participants. People with a history of allergic reactions to vaccines were excluded from the study.

One of the panel members, Dr. Paul Offit of the Children’s Hospital of Philadelphia, said he feared that statements by British regulators as well as remarks by Moncef Slaoui, a top U.S. vaccine official, could lead “tens of millions” of people with severe allergies to reject the vaccine even though evidence of a link to the shots was unclear. He asked Pfizer to conduct a separate study of people with a history of severe allergies, because “this issue is not going to die until we have better data.”

The F.D.A. said that it had asked Pfizer to include allergic reactions in its safety tracking plan and would include a warning in its instructions on the use of the vaccine.

One of the most hotly contested issues was how the broad authorization of the vaccine might affect the continuing clinical trial. Some experts have argued that, ethically, trial volunteers who received a placebo should be offered the vaccine once it is authorized, but others worried that move could tarnish the long-term results of the trial.

During the public portion of the meeting, consumer and public health advocates largely pushed the agency to authorize the vaccine, noting the urgency of the pandemic. One speaker, who identified himself as Kermit Kubitz, noted that he had no conflicts of interest to declare except for “a lot of elderly relatives.”

“They need this vaccine yesterday,” he said.

But advocates also asked regulators to be transparent about potential safety issues and to closely track the vaccine once it becomes available. Several said such measures were necessary to reassure a public that is hesitant to take a new vaccine, particularly Black and Native American people who have historically been mistreated by the medical community. “Before authorization is granted, affected communities need to have confidence that the vaccine is safe and effective,” said Sarah Christopherson of the National Women’s Health Center.

By insisting that the advisory committee vote on any vaccine, regulators created a shield against White House pressure to approve a product before the presidential election. When the panelists met in October to discuss the F.D.A.’s guidelines for approving Covid-19 vaccines, they urged the agency to take its time and cautioned that rushing the process could risk missing vital safety data and further erode public trust.

The scene that played out on Thursday — in which outside experts spent hours engaging government officials in an intense but often highly technical discussion about vaccine science — did not always make for exciting viewing. But the circumstances were certainly dramatic, as the experts were being asked to carefully weigh the risks and benefits of the vaccine, even as the United States reached the grim milestone of recording more than 3,000 Covid deaths on Wednesday and as thousands of people in Britain had already received it.

The F.D.A. has struggled, internally and externally, to move fast on its vaccine and treatment deliberations in order to curb the deadly virus’s spread — but not so fast as to undermine public confidence. It was a thin line to walk, and not helped by the torrent of troubling accusations by Mr. Trump and his advisers that the agency was moving too slowly.

Just days before Pfizer submitted its application, the company sent an enormous tranche of manufacturing data to the F.D.A. — including materials on how it was scaling up production — leaving regulators scrambling to evaluate it in time for a possible authorization.

As part of its oversight, the F.D.A. also had teams review company production facilities and clinical trial sites, where they verified that records corresponded to the accounts Pfizer had submitted to federal regulators.

At the same time, regulators were evaluating an equally complex emergency authorization application submitted by Moderna, whose data will be examined publicly during another F.D.A. outside advisory meeting next week.

The Road to a Coronavirus Vaccine ›

Answers to Your Vaccine Questions

As the coronavirus vaccine get closer to U.S. authorization, here are some questions you may be wondering about:

    • If I live in the U.S., when can I get the vaccine? While the exact order of vaccine recipients may vary by state, most will likely put medical workers and residents of long-term care facilities first. If you want to understand how this decision is getting made, this article will help.
    • When can I return to normal life after being vaccinated? Life will return to normal only when society as a whole gains enough protection against the coronavirus. Once countries authorize a vaccine, they’ll only be able to vaccinate a few percent of their citizens at most in the first couple months. The unvaccinated majority will still remain vulnerable to getting infected. A growing number of coronavirus vaccines are showing robust protection against becoming sick. But it’s also possible for people to spread the virus without even knowing they’re infected because they experience only mild symptoms or none at all. Scientists don’t yet know if the vaccines also block the transmission of the coronavirus. So for the time being, even vaccinated people will need to wear masks, avoid indoor crowds, and so on. Once enough people get vaccinated, it will become very difficult for the coronavirus to find vulnerable people to infect. Depending on how quickly we as a society achieve that goal, life might start approaching something like normal by the fall 2021.
    • If I’ve been vaccinated, do I still need to wear a mask? Yes, but not forever. The two vaccines that will potentially get authorized this month clearly protect people from getting sick with Covid-19. But the clinical trials that delivered these results were not designed to determine whether vaccinated people could still spread the coronavirus without developing symptoms. That remains a possibility. We know that people who are naturally infected by the coronavirus can spread it while they’re not experiencing any cough or other symptoms. Researchers will be intensely studying this question as the vaccines roll out. In the meantime, even vaccinated people will need to think of themselves as possible spreaders.
    • Will it hurt? What are the side effects? The Pfizer and BioNTech vaccine is delivered as a shot in the arm, like other typical vaccines. The injection won’t be any different from ones you’ve gotten before. Tens of thousands of people have already received the vaccines, and none of them have reported any serious health problems. But some of them have felt short-lived discomfort, including aches and flu-like symptoms that typically last a day. It’s possible that people may need to plan to take a day off work or school after the second shot. While these experiences aren’t pleasant, they are a good sign: they are the result of your own immune system encountering the vaccine and mounting a potent response that will provide long-lasting immunity.
    • Will mRNA vaccines change my genes? No. The vaccines from Moderna and Pfizer use a genetic molecule to prime the immune system. That molecule, known as mRNA, is eventually destroyed by the body. The mRNA is packaged in an oily bubble that can fuse to a cell, allowing the molecule to slip in. The cell uses the mRNA to make proteins from the coronavirus, which can stimulate the immune system. At any moment, each of our cells may contain hundreds of thousands of mRNA molecules, which they produce in order to make proteins of their own. Once those proteins are made, our cells then shred the mRNA with special enzymes. The mRNA molecules our cells make can only survive a matter of minutes. The mRNA in vaccines is engineered to withstand the cell’s enzymes a bit longer, so that the cells can make extra virus proteins and prompt a stronger immune response. But the mRNA can only last for a few days at most before they are destroyed.

Regulators sometimes received documents from the companies as late as midnight and worked through the Thanksgiving holiday. Dr. Peter Marks, the top vaccine regulator at the F.D.A., joked last week at an event hosted by the American Medical Association that his team ate turkey sandwiches while examining documents.

“Among all global regulators, we are the ones that actually don’t just look at the company’s tables. We actually get down and dirty and we look at the actual adverse event reports, the bad spelling errors that are made by physicians sometimes, et cetera,” he said at the event.

Dr. Stephen M. Hahn, the F.D.A. commissioner, kept a careful distance from the review, according to people familiar with it.

Dr. Hahn had caved to pressure earlier in the summer to authorize an old malaria drug, hydroxychloroquine, for use in Covid patients even though there was little evidence that it worked. That decision was reversed after the agency found the drug was unlikely to be effective in Covid patients and carried a risk of potentially dangerous side effects. And Dr. Hahn faced withering criticism from the scientific community after he exaggerated the benefits of another treatment, convalescent plasma, an error he later corrected.

Mr. Trump accused agency officials of being part of the “deep state” and hinted that a vaccine could come before “a very special day” — Election Day. The F.D.A.’s reputation appeared to be headed in the same direction as that of the Centers for Disease Control and Prevention, which was widely criticized for not standing up to the president.

But senior regulators — and eventually Dr. Hahn himself — pushed back. The agency’s top career officials published an opinion piece in USA Today, acknowledging that the F.D.A.’s integrity had been called into question and insisting that they would “follow the science” during the pandemic. The agency prevailed in a battle with the White House over imposing more stringent guidelines for companies developing Covid vaccines.

“In this sort of environment, where there has been so much pressure and concern, the process does provide an important check and balance,” said Dr. Jesse L. Goodman, who previously served as the F.D.A.’s chief scientist. Holding an open meeting also allows the public to “be sure that a broader scientific and clinical community is comfortable with the decision.”

On Tuesday, the president held a summit intended to showcase the administration’s role in developing a vaccine. “We are just days away from authorization from the F.D.A. and we’re pushing them hard,” Mr. Trump said at the event.

Many health care workers around the country are already raring to get the vaccine. Dr. Andrew Barros, a critical care physician in Charlottesville, Virginia, who is scheduled to get his Pfizer shot at 2:30 p.m. on Dec. 15, said he is “looking forward to having a sore arm and hopefully being one step closer to having Covid under control.”

Pfizer’s clinical trial will continue even after its vaccine is authorized by the F.D.A., and the company and F.D.A. will continue to watch for safety concerns.

Pfizer said on Thursday that it planned to apply for full approval in April of 2021, after the company had collected six months of safety data. At that point, Pfizer would be allowed to sell its vaccine directly to hospitals and other health care providers.

Carl Zimmer and Katherine J. Wu contributed reporting.

Categories
Politics

Pentagon Weighs Sharp Disadvantage in Assist for C.I.A.

WASHINGTON – The Trump administration is considering withdrawing military support to the CIA, including the potential withdrawal of much of the CIA-operated drone fleet, according to current and former officials. The postponement could severely limit the agency’s counter-terrorism efforts, which expanded significantly after the September 11, 2001 attacks.

The government is considering several options that could go into effect as early as January 5th. One would reduce the number of Pentagon personnel posted to the agency – many of them special forces forces who work in the CIA’s paramilitary division. However, other changes that are being considered would be far broader and more consistent, making it difficult for the agency to operate from military bases, use the Department of Defense’s medical evacuation capabilities, or conduct covert drone strikes against terrorists at hot spots around the world.

Former officials warned President-elect Joseph R. Biden Jr. can reverse changes immediately as soon as he takes office next month. However, depending on how quickly the Pentagon makes such decisions, it might be more difficult for the new administration to reverse them quickly.

It wasn’t clear why the Trump administration was pushing its review as Mr Biden could easily turn it back. Some former agency officials viewed the move as a final attempt by President Trump, who has long berated intelligence services for their assessment that Russia intervened to support its 2016 presidential campaign and downsize the CIA

The Pentagon is currently reviewing a 15-year-old memorandum of understanding with the CIA to move some staff from supporting the agency to other posts, a senior administration official said. Some in the Pentagon believe the CIA has received too many military assets, and the Department of Defense wants a greater say in their allocation.

Ezra Cohen-Watnick, who was appointed assistant secretary of defense for intelligence last month and seen among some career officials as a highly ideological Trump loyalist, pushed the effort forward, current and former officials said. Christopher C. Miller, the acting Secretary of Defense and longtime Army Green Beret, supports it as long overdue and part of the business as usual for the Pentagon, which, according to a senior American official, has to constantly review how it is using its assets.

“The Pentagon has tried to better use its resources to focus more on the so-called great power competition with China,” Air Force Lt. Col. Uriah L. Orland replied to a request for comment when asked for comment.

“Much has changed in the first two decades of this century, and DOD is only working with the CIA to ensure that both DOD and CIA are able to work together to address United States national security challenges,” he said.

While the CIA refused to discuss the deliberations, Nicole de Haay, a spokeswoman for the agency, said she was confident that close cooperation with the Department of Defense would continue “for years to come.”

“There is no stronger relationship and no better partnership,” she said. “This partnership has resulted in achievements that have greatly improved US national security.”

The review includes the assignment of counter-terrorism military experts, which the Pentagon referred to the CIA, but the changes could be more extensive, according to those briefed on the effort.

One version of the plan could reduce the number of military bases the Pentagon makes available to the CIA and even reduce the number of places in the world where the Department of Defense provides medical evacuation and treatment to officials and contractors.

“That would be a setback for US national security,” said Michael P. Mulroy, former Pentagon chief Middle East policy officer and former CIA paramilitary officer, in an email about the proposed changes. “As a team, this relationship resulted in some of the greatest successes in Afghanistan, Iraq and the global war on terrorism.”

Defense One covered the Pentagon Review earlier.

Since the 9/11 attacks, the CIA has replenished its small number of unmanned armed drones with assets and pilots on loan from the Pentagon. According to former officials, around two-thirds to three-quarters of the CIA’s drone fleet is now owned and loaned to the agency by the Air Force.

The CIA’s strikes are undercover and are not recognized by the agency. During the Bush and Obama administrations, the CIA used military drones to carry out increasingly deadly air strikes in Pakistan, Yemen, Somalia and elsewhere. The CIA, not the military, has carried out some of the government’s airstrikes in recent decades because some host countries prevented the American military from operating on their territory. The CIA can also act faster, argued former officials.

“The CIA’s process of authorizing lethal strikes against individuals is faster than the military’s more bureaucratic procedures,” said Kevin Carroll, a former CIA officer. “In this way, decaying, time-critical counter-terrorism goals could be missed.”

CIA drone strikes have decreased in recent years, and the agency has pulled back from strikes in some countries, such as Pakistan, that were once the focus of its operations, according to former officials.

Last year, the Trump administration began curtailing the nation’s counter-terrorism efforts to shift the focus of intelligence agencies to China. That year, Richard Grenell, then acting director of the National Intelligence Service, ordered a review of the National Counter-Terrorism Center, which resulted in its size being reduced.

Human rights groups are likely to welcome a further reduction in CIA air strikes. You have long spoken out against the targeted murder of terrorist suspects by the government, but you were particularly frustrated with the secret nature of the CIA program.

“The CIA shouldn’t be responsible for targeted murders because it can’t naturally meet international transparency standards,” said Andrea J. Prasow, Washington deputy director at Human Rights Watch.

The Pentagon has told Biden interim officials that it is reviewing its agreement to assist the CIA in the effort to shift resources from the counter-terrorism mission to the Chinese threat.

Most administrations withhold important decisions in the final days of a president’s term with profound consequences. Former officials say the revision of the operating agreement between the CIA and the Pentagon is exactly that kind of change with global implications that should be left to the Biden administration.

However, the deal could make it difficult for the CIA to conduct some of its operations in Afghanistan next month as the Pentagon tries to reduce the number of soldiers there. However, people who have been briefed on the matter say the military continues to support the CIA despite the drawdown orders.

The close ties between the CIA and special military operations personnel were underscored last month when a CIA paramilitary officer was killed in Somalia. General Mark A Milley, chairman of the joint chiefs of staff, publicly announced the official’s death in a comment last week to a think tank. General Milley noted that the officer had previously served in the military as a member of the Navy SEALs.

The Pentagon announced last week that virtually all of Somalia’s 700 or so troops – most of the special forces that have conducted training and counter-terrorism missions – will leave by January 15, five days before Mr Biden’s inauguration.

Military officials said the Pentagon will continue to conduct counter-terrorism operations from neighboring Djibouti and Kenya, but the withdrawal of American forces is likely to complicate the role of CIA paramilitary officers remaining in Somalia.

Over the past two decades, the military-CIA partnership has halted “numerous terrorist attacks,” said Marc Polymeropoulos, a former CIA officer who has spent much of his career fighting terrorism.

“The fight against terrorism is not over yet, even if we turn to competition from China and Russia,” he said. “This reported move also puts CIA staff at considerable risk. At a time when a CIA officer was recently killed in Somalia, it is hard to imagine why the Department of Defense would pull the necessary Medevac platforms for our officers at the tip of the spear. “

Categories
Business

Disney Investor Day 2020 bulletins

Bob Chapek, CEO of the Walt Disney Company and former head of Walt Disney Parks and Experiences, speaks during a media preview of the 2019 D23 Expo in Anaheim, California on August 22, 2019.

Patrick T. Fallon | Bloomberg via Getty Images

The SDisney streaming service Disney + continues to gain subscribers. On Thursday, the company announced that the platform now has 86.8 million subscribers on its annual investor day. That’s more than the 73 million the company reported at the end of its fourth fiscal quarter.

The company’s shares rose 3% on the news.

As of December 2, the company also has 38.8 million Hulu subscribers and 11.5 million ESPN + subscribers.

The entertainment giant’s stock hit a record close of $ 154.69 on Thursday, just before the company’s annual investor event, which is set to announce plans for 2021 and beyond. Disney stock hit an intraday all-time high of $ 155.34 on Thursday.

After rival Warner Bros. announced that it would release 17 films the same day on HBO Max and in theaters the next day, analysts and investors are excited to see how Disney will maneuver through the uncertainty still looming from a global pandemic is.

Kareem Daniel, head of the company’s new media and entertainment sales group, said theatrical releases help build franchises. Something Disney has done well with blockbusters from Marvel and Star Wars over the past decade.

Daniel announced that in Disney + 10 Marvel series, 10 Star Wars series, 15 Disney live action, Disney animation and Pixar series, and 15 Disney live action, Disney animation and Pixar series -Films will be shown.

The company will simultaneously be releasing the Raya and the Last Dragon animated feature on premium video-on-demand via Disney + and in theaters.

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Categories
Health

Unwanted effects are indicators shot is constructing safety, says ex-FDA chief

Covid-19 vaccine side effects are signs that the shots are helping to protect against the disease, said former FDA chief Dr. Margaret Hamburg on Thursday opposite CNBC.

“The data tell us that this vaccination produces a fairly routine response at the time of administration, but it is noteworthy when you receive the vaccine,” she said on Squawk Box. “You will know when you will receive the vaccine, but that will also show you that it works and that your body is reacting,” added Hamburg, who headed the regulator in the Obama administration from 2009 to 2015.

The Hamburg statements come when the vaccine committee of the Food and Drug Administration meets on Thursday whether Pfizer and German partner BioNTech should vote for the emergency approval of the Covid-19 candidate. The non-binding decision by the panel of experts is a final step before the FDA is expected to approve the vaccine for limited use.

The agency will meet next week at the request of Massachusetts-based Moderna to obtain the same approval. The vaccine is similar to Pfizer’s in that they both take a new approach that uses genetic material to trigger an immune response.

Pfizer’s vaccine was approved by regulators in the UK last week, where the first shots for non-trial participants were given on Tuesday. However, the two allergic reactions reported by UK health workers prompted UK regulators to advise people with a history of “significant” allergic reactions to abstain from the vaccine for the time being.

Coronavirus vaccine development deadlines have been hastened this year by drug makers and governments alike in hopes of finding a solution to the devastating pandemic that killed at least 1,571,890 people worldwide, according to Johns Hopkins University. The US recorded a record 3,124 deaths on Wednesday.

Both Pfizer’s and Moderna’s vaccines were shown to be more than 94% effective in preventing symptomatic Covid-19, according to data from large-scale clinical trials.

Some of the reported side effects are “local swelling, irritation, pain, fatigue, sometimes headache,” said Hamburg. “A percentage of the patients had chills and a slight fever.”

Dr. Moncef Slaoui, who leads the Trump administration’s vaccine development efforts, has defended the safety of Pfizer and Moderna vaccines. He said earlier this month that “significantly noticeable” side effects from the admissions were reported in only 10% to 15% of study participants, which may lasted up to a day and a half.

Both Pfizer’s and Moderna’s vaccines require two doses. Some doctors have tried to raise awareness of the side effects so that vaccine recipients aren’t deterred from getting the second shot.

“We really need to make patients aware that this is not going to be a walk in the park,” said Dr. Sandra Fryhofer of the American Medical Association in November at an advisory panel meeting of the Centers for Disease Control and Prevention. “You will know you had a vaccine. You probably won’t feel wonderful. But you have to come back for that second dose.”

Categories
World News

ABNB begins buying and selling on the Nasdaq

The NASDAQ market page will display an AirBnb sign on their billboard on the day of their IPO in Times Square in the Manhattan neighborhood of New York City, New York, United States, on December 10, 2020.

Carlo Allegri | Reuters

Airbnb is set to double its share price by its IPO debut on Thursday at the latest in a wave of hotly anticipated tech IPOs in a year that has been tumultuous due to the pandemic.

The shares were priced at $ 68 on Wednesday and are expected to hit around $ 152.30 when the stock starts trading, according to early signs prior to initial trading. Airbnb is traded on the Nasdaq under the ticker “ABNB”.

The stock is expected to trade between 12:30 p.m. and 1:00 p.m. Eastern Time, a well-placed source CNBC’s Leslie Picker said. Speculation that it would join one of the major indexes in the next few years seems to be sparking interest, the source said.

The company is going public at a time when the sector was hit by reduced travel trends during the public health crisis. Revenue last quarter was down nearly 19% to $ 1.34 billion year over year. But it still managed to make a profit of $ 219 million, and there were other intermittently profitable quarters as well.

While travel was less, Airbnb managed to find a sweet spot for those willing to hit the road who prefer home stays over traditional hotels. That could change when vaccines make travel more accessible again, possibly as early as late next year.

Airbnb’s CEO Brian Chesky said in an interview with CNBC’s Deirdre Bosa on the Thursday ahead of its IPO that the platform is considering changing the way travelers want to plan their trips as remote working is an option for many.

“Now that people come to Airbnb, they don’t even necessarily have a destination or dates in mind because they’re flexible. We’re all obviously zoomed in, and that’s why people say, ‘I want to go anywhere 300 miles around me around, what can you show me? ‘”he said. “Now we’re going to dig a little more into the game of inspiration and tune people into the perfect home experience for them.”

Chesky also said he wasn’t too concerned about the rating.

“I don’t think I’ll be more concerned than I did in April and May when our business fell 80% in eight weeks in the middle of a pandemic,” he said.

Airbnb struggled with complaints from hosts on its platform at the beginning of the pandemic, when the company indulged guest cancellations, leaving hosts with no expected payments. A Texas-based host filed a class action lawsuit against the company last month alleging that Airbnb breached its contract with hosts by offering the refunds. Airbnb called the lawsuit “frivolous and without merit” in a statement at the time.

As part of its IPO, Airbnb set up a Host Endowment Fund made up of 9.2 million non-voting shares. Airbnb said in its IPO prospectus that the fund would benefit hosts through programs and grants.

“We want hosts to share in our success, not just for a moment, but as long as Airbnb exists in the world,” the company wrote. “We intend that the Host Endowment Fund will be a long-term investment in the future of our hosting community, built by hosts for hosts.”

Airbnb was listed eight times on CNBC’s annual Disruptor 50 list and ranks 41st in 2020 Disruptor 50 companies.

This story evolves. Check for updates again.

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WATCH: Airbnb is battling through its Covid-19 response